|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Molecular Mechanisms of Leaf Morphogenesis显示文摘工厂维持能力作为茎的主要侧面的附器在整个他们的生命周期和形式叶子形成侧面的附器。叶子在射击的外部地区开始顶端的分裂组织然后发展成弄平的结构。在大多数植物,叶作为一块太阳的面板工作,在光合作用把二氧化碳和水变换成糖类和氧的地方。为了生产结构,那能最佳地完成这功能,植物精确控制叶子的开始,形状,和极性。而且,叶开发是高度灵活的 ? 但是与保存规章的机制跟随普通主题。叶子可能从被变换成确定的、弄平的结构的侧面的分支演变。许多另外的植物部分例如花的器官,被认为专业化叶子,并且因此,叶开发位于他们的形态发生下面。这里,我们在三维的叶形式怎么被建立的理解考察最近的进展。我们集中基因,植物激素,和机械性质怎么调制叶开发,并且讨论 ? 在叶开始,极性建立和维护,变平的叶,和闰的生长的上下文的这些因素。 | Fei Du Chunmei Guan Yuling Jiao | 2018 | Molecular Plant2018，11，9： | 25 |
| 2 | Single-cell transcriptome analysis reveals widespread monoallelic gene expression in individual rice mesophyll cells显示文摘Monoallelic gene expression refers to the phenomenon that all transcripts of a gene in a cell are expressed from only one of the two alleles in a diploid organism. Although monoallelic gene expression has been occasionally reported with bulk transcriptome analysis in plants, how prevalent it is in individual plant cells remains unknown. Here, we developed a single-cell RNA-seq protocol in rice and investigated allelic expression patterns in mesophyll cells of indica(93-11) and japonica(Nipponbare) inbred lines, as well as their F1 reciprocal hybrids. We observed pervasive monoallelic gene expression in individual mesophyll cells, which could be largely explained by stochastic and independent transcription of two alleles. By contrast, two mechanisms that were proposed previously based on bulk transcriptome analyses, parent-oforigin effects and allelic repression, were not well supported by our data. Furthermore, monoallelically expressed genes exhibited a number of characteristics, such as lower expression levels, narrower H3K4me3/H3K9ac/H3K27me3 peaks, and larger expression divergences between 93-11 and Nipponbare. Taken together, the development of a single-cell RNA-seq protocol in this study offers us an excellent opportunity to investigate the origins and prevalence of monoallelic gene expression in plant cells. | Yingying Han Xiao Chu Haopeng Yu Ying-Ke Ma Xiu-Jie Wang Wenfeng Qian Yuling Jiao | 2017 | Science Bulletin2017，62，19： | 5 |
| 3 | Transcriptome Survey of the Contribution of Alternative Splicing to Proteome Diversity in Arabidopsis thaliana显示文摘 | Haopeng Yu Caihuan Tian Yang Yu Yuling Jiao | 2016 | Molecular Plant2016，9，5： | 4 |
| 4 | Colour compound lenses for a portable fluorescence microscope显示文摘In this article,we demonstrated a handheld smartphone fluorescence microscope(HSFM)that integrates dualfunctional polymer lenses with a smartphone.The HSFM consists of a smartphone,a field-portable illumination source,and a dual-functional polymer lens that performs both optical imaging and filtering.Therefore,compared with the existing smartphone fluorescence microscope,the HSFM does not need any additional optical filters.Although fluorescence imaging has traditionally played an indispensable role in biomedical and clinical applications due to its high specificity and sensitivity for detecting cells,proteins,DNAs/RNAs,etc.,the bulky elements of conventional fluorescence microscopes make them inconvenient for use in point-of-care diagnosis.The HSFM demonstrated in this article solves this problem by providing a multifunctional,miniature,small-form-factor fluorescence module.This multifunctional fluorescence module can be seamlessly attached to any smartphone camera for both bright-field and fluorescence imaging at cellular-scale resolutions without the use of additional bulky lenses/filters;in fact,the HSFM achieves magnification and light filtration using a single lens.Cell and tissue observation,cell counting,plasmid transfection evaluation,and superoxide production analysis were performed using this device.Notably,this lens system has the unique capability of functioning with numerous smartphones,irrespective of the smartphone model and the camera technology housed within each device.As such,this HSFM has the potential to pave the way for realtime point-of-care diagnosis and opens up countless possibilities for personalized medicine. | Bo Dai Ziao Jiao Lulu Zheng Hunter Bachman Yongfeng Fu Xinjun Wan Yule Zhang Yu Huang Xiaodian Han Chenglong Zhao Tony Jun Huang Songlin Zhuang Dawei Zhang | 2019 | Light(Science & Applications)2019，8，1： | 3 |
| 5 | Plant multiscale networks:charting plant connectivity by multi-level analysis and imaging techniques显示文摘In multicellular and even single-celled organisms,individual components are interconnected at multiscale levels to produce enormously complex biological networks that help these systems maintain homeostasis for development and environmental adaptation.Systems biology studies initially adopted network analysis to explore how relationships between individual components give rise to complex biological processes.Network analysis has been applied to dissect the complex connectivity of mammalian brains across different scales in time and space in The Human Brain Project.In plant science,network analysis has similarly been applied to study the connectivity of plant components at the molecular,subcellular,cellular,organic,and organism levels.Analysis of these multiscale networks contributes to our understanding of how genotype determines phenotype.In this review,we summarized the theoretical framework of plant multiscale networks and introduced studies investigating plant networks by various experimental and computational modalities.We next discussed the currently available analytic methodologies and multi-level imaging techniques used to map multiscale networks in plants.Finally,we highlighted some of the technical challenges and key questions remaining to be addressed in this emerging field. | Xi Zhang Yi Man Xiaohong Zhuang Jinbo Shen Yi Zhang Yaning Cui Meng Yu Jingjing Xing Guangchao Wang Na Lian Zijian Hu Lingyu Ma Weiwei Shen Shunyao Yang Huimin Xu Jiahui Bian Yanping Jing Xiaojuan Li Ruili Li Tonglin Mao Yuling Jiao Sodmergen Haiyun Ren Jinxing Lin | 2021 | Science China(Life Sciences)2021，64，9： | 3 |
| 6 | Condensation of STM is critical for shoot meristem maintenance and salt tolerance in Arabidopsis显示文摘The shoot meristem generates the entire shoot system and is precisely maintained throughout the life cycle under various environmental challenges.In this study,we identified a prion-like domain(PrD)in the key shoot meristem regulator SHOOT MERISTEMLESS(STM),which distinguishes STM from other related KNOX1 proteins.We demonstrated that PrD stimulates STM to form nuclear condensates,which are required for maintaining the shoot meristem.STM nuclear condensate formation is stabilized by selected PrD-containing STM-interacting BELL proteins in vitro and in vivo.Moreover,condensation of STM promotes its interaction with the Mediator complex subunit MED8 and thereby enhances its transcriptional activity.Thus,condensate formation emerges as a novel regulatory mechanism of shoot meristem functions.Furthermore,we found that the formation of STM condensates is enhanced upon salt stress,which allows enhanced salt tolerance and increased shoot branching.Our findings highlight that the transcription factor partitioning plays an important role in cell fate determination and might also act as a tunable environmental acclimation mechanism. | Xiuwei Cao Qingwei Du Yahe Guo Ying Wang Yuling Jiao | 2023 | Molecular Plant2023，16，9： | 2 |
| 7 | The 35S promoter-driven mDII auxin control sensor is uniformly distributed in leaf primordia显示文摘The DII auxin sensor has been an invaluable tool for mapping the spatiotemporal auxin response and distribution in the model plant Arabidopsis thaliana.The DII sensor and the m DII control sensor are driven by the widely used constitutive 35S promoter. | Chunmei Guan Fei Du Yuanyuan Xiong Yuling Jiao | 2019 | Journal of Integrative Plant Biology2019，61，11： | 2 |
| 8 | A near-complete assembly of an Arabidopsis thaliana genome显示文摘The genome sequence of Arabidopsis thaliana,a widely adopted model species,has greatly expedited plant molecular biology research.Over 20 years after the first release of the genome sequence(Arabidopsis Genome Initiative,2000),there remains unresolved gap regions that are presumably composed of highly repetitive sequences,such as telomeres,centromeres,5S rDNA clusters,and nucleolar organizerregions(NORs)containing 45S rDNA. | Xueren Hou Depeng Wang Zhukuan Cheng Ying Wang Yuling Jiao | 2022 | Molecular Plant2022，15，8： | 2 |
| 9 | A Rate of Convergence of Physics Informed Neural Networks for the Linear Second Order Elliptic PDEs显示文摘In recent years,physical informed neural networks(PINNs)have been shown to be a powerful tool for solving PDEs empirically.However,numerical analysis of PINNs is still missing.In this paper,we prove the convergence rate to PINNs for the second order elliptic equations with Dirichlet boundary condition,by establishing the upper bounds on the number of training samples,depth and width of the deep neural networks to achieve desired accuracy.The error of PINNs is decomposed into approximation error and statistical error,where the approximation error is given in C2 norm with ReLU^(3)networks(deep network with activation function max{0,x^(3)})and the statistical error is estimated by Rademacher complexity.We derive the bound on the Rademacher complexity of the non-Lipschitz composition of gradient norm with ReLU^(3)network,which is of immense independent interest. | Yuling Jiao Yanming Lai Dingwei Li Xiliang Lu Fengru Wang Yang Wang Jerry Zhijian Yang | 2022 | Communications in Computational Physics2022，31，4： | 2 |
| 10 | May the Force Be with You: Overlooked Mechanical Signaling显示文摘Within multicellular plants, cells constantly communicate with their neighbors and even distant cells. A cell may produce chemical signals, such as peptides and small molecules, and perceive chemical signals from other cells. Thus, signaling chemicals mediate the exchange of information between cells. There is a simpler and faster way for cells to communicate, i.e., a cell can mechanically nudge its neighbors to send a signal. However, mechanical force is often ignored by biologists, partially due to the difficulty in directly visualizing the force, in contrast to visual detection of signaling molecules. | Yuling Jiao | 2019 | Molecular Plant2019，12，4： | 1 |
| 11 | Global genome expression analysis of rice in response to drought and high-salinity stresses in shoot, flag leaf, and panicle显示文摘 | Junli Zhou Xiangfeng Wang Yuling Jiao Yonghua Qin Xigang Liu Kun He Chen Chen Ligeng Ma Jian Wang Lizhong Xiong Qifa Zhang Liumin Fan Xing Wang Deng | 2007 | Plant Molecular Biology2007，，5： | 1 |
| 12 | Flow Characteristics of Crude Oil with High Water Fraction during Non-heating Gathering and Transportation显示文摘In order to ensure the safety of the non-heating gathering and transportation processes for high water fraction crude oil,the effect of temperature,water fraction,and flow rate on the flow characteristics of crude oil with high water fraction was studied in a flow experimental system of the X Oilfield.Four distinct flow patterns were identified by the photographic and local sampling techniques.Especially,three new flow patterns were found to occur below the pour point of crude oil,including EW/O&W stratified flow with gel deposition,EW/O&W intermittent flow with gel deposition,and water single-phase flow with gel deposition.Moreover,two characteristic temperatures,at which the change rate of pressure drop had changed obviously,were found during the change of pressure drop.The characteristic temperature of the first congestion of gel deposition in the pipeline was determined to be the safe temperature for the non-heating gathering and transportation of high water cut crude oil,while the pressure drop reached the peak at this temperature.An empirical formula for the safe temperature was established for oil-water flow with high water fraction/low fluid production rate.The results can serve as a guide for the safe operation of the non-heating gathering and transportation of crude oil in high water fraction oilfields. | LüYuling Tan Hao Li Jiao Yang Donghai Xu Peiyang | 2021 | China Petroleum Processing & Petrochemical Technology2021，23，1： | 1 |
| 13 | Cellulose Microfibril-Mediated Directional Plant Cell Expansion:Gas and Brake显示文摘Directional cell expansion is a fundamental process that is involved in virtually all cellular processes.Divergence from isotropic growth is commonly associated with cell fate transition,organ shaping,or cell maturation.To obtain continuous direc-tional cell growth,and tissue and organ growth as well,positive feedback loops are needed to lock anisotropic cell expansion.On the other hand,antagonistic mechanisms are needed to terminate directional cell expansion.Many genes affecting cell shape have been identified,but only in a few cases do we under-stand the precise chains of molecular events to some extent.Recently,a cortical microtubule(CMT)-mediated mechanical feedback loop has been recognized that amplifies tensile stress anisotropy and leads to expansion perpendicular to the stress di-rection(Sampathkumar,2020;Zhao et al.,2020)(Figure 1A).By contrast,passive reorientation of cellulose microfibrils(CMFs)may form a combative mechanism that cancels directional cell expansion(Figure 1B).However,passive CMF reorientation is insufficiently recognized by developmental biologists who are interested in directional cell expansion,anisotropic tissue growth,and organ shaping. | Ying Wang Yuling Jiao | 2020 | Molecular Plant2020，13，12： | 1 |
| 14 | Dynamic patterns of gene expression during leaf initiation显示文摘The establishment of leaf dorsoventral(adaxial-abaxial)polarity conditions flattening of the leaf,an essential feature of land plants that optimizes light absorbance.Leaf primordia initiate from peripheral zone(PZ)at the flank of the shoot apical meristem(SAM),which maintains stem cells in the shoot apex.Soon after initiation,asymmetries in leaves become established.Extensive molecular genetic studies have identified a transcriptional regulatory network of adaxial-and abaxial-promoting genes,which | Ting Yu Chunmei Guan Jin Wang Muhammad Sajjad Lingjian Ma Yuling Jiao | 2017 | Journal of Genetics and Genomics2017，44，12： | 1 |
| 15 | A crosstalk between auxin and brassinosteroid regulates leaf shape by modulating growth anisotropy显示文摘Leaf shape is highly variable within and among plant species,ranging from slender to oval shaped.This is largely determined by the proximodistal axis of growth.However,little is known about how proximal–distal growth is controlled to determine leaf shape.Here,we show that Arabidopsis leaf and sepal proximodistal growth is tuned by two phytohormones.Two class A AUXIN RESPONSE FACTORs(ARFs),ARF6 and ARF8,activate the transcription of DWARF4,which encodes a key brassinosteroid(BR)biosynthetic enzyme.At the cellular level,the phytohormones promote more directional cell expansion along the proximodistal axis,as well as final cell sizes.BRs promote the demethyl-esterification of cell wall pectins,leading to isotropic in-plane cell wall loosening.Notably,numerical simulation showed that isotropic cell wall loosening could lead to directional cell and organ growth along the proximodistal axis.Taken together,we show that auxin acts through biosynthesis of BRs to determine cell wall mechanics and directional cell growth to generate leaves of variable roundness. | Yuanyuan Xiong Binbin Wu Fei Du Xiaolu Guo Caihuan Tian Jinrong Hu Shouqin Lii Mian Long Lei Zhang Ying Wang Yuling Jiao | 2021 | Molecular Plant2021，14，6： | 1 |
| 16 | Variable Selection via Generalized SELO-Penalized Cox Regression Models显示文摘The seamless-L_0(SELO) penalty is a smooth function that very closely resembles the L_0 penalty, which has been demonstrated theoretically and practically to be effective in nonconvex penalization for variable selection. In this paper, the authors first generalize the SELO penalty to a class of penalties retaining good features of SELO, and then develop variable selection and parameter estimation in Cox models using the proposed generalized SELO(GSELO) penalized log partial likelihood(PPL) approach. The authors show that the GSELO-PPL procedure possesses the oracle property with a diverging number of predictors under certain mild, interpretable regularity conditions. The entire path of GSELO-PPL estimates can be efficiently computed through a smoothing quasi-Newton(SQN) with continuation algorithm. The authors propose a consistent modified BIC(MBIC) tuning parameter selector for GSELO-PPL, and show that under some regularity conditions, the GSELOPPL-MBIC procedure consistently identifies the true model. Simulation studies and real data analysis are conducted to evaluate the finite sample performance of the proposed method. | SHI Yueyong XU Deyi CAO Yongxiu JIAO Yuling | 2019 | Journal of Systems Science & Complexity2019，32，2： | 1 |
| 17 | AUXIN RESPONSE FACTOR 3 integrates the functions of AGAMOUS and APETALA 2 in floral meristem determinacy显示文摘 | Xigang Liu Thanh Theresa Dinh Dongming Li Bihai Shi Yongpeng Li Xiuwei Cao Lin Guo Yanyun Pan Yuling Jiao Xuemei Chen | 2014 | Plant J2014，，4： | 1 |
| 18 | Multifaceted functions of auxin in vegetative axillary meristem initiation显示文摘Plants developed branching as an evolutionary mechanism to adapt to their sessile nature. In seed plants, branching requires the postembryonic initiation of axillary meristems (AMs). AMs are initiated in the leaf axils, where the boundary region separates the leaves from the stem. AMs share comparable developmental potential as the shoot apical meristem (SAM) and form axillary buds, which may either develop into branches or remain dormant. | Yahe Guo Caihuan Tian Yuling Jiao Ying Wang | 2020 | Journal of Genetics and Genomics2020，47，9： | 0 |
| 19 | The commensal consortium of the gut microbiome is associated with favorable responses to anti-programmed death protein 1 (PD-1) therapy in thoracic neoplasms显示文摘Objective:Immune checkpoint inhibitors have revolutionized cancer therapy for multiple types of solid tumors,but as expected,a large percentage of patients do not show durable responses.Biomarkers that can predict clinical responses to immunotherapies at diagnosis are therefore urgently needed.Herein,we determined the associations between baseline gut commensal microbes and the clinical treatment efficiencies of patients with thoracic neoplasms during anti-programmed death protein 1(PD-1)therapy.Methods:Forty-two patients with advanced thoracic carcinoma who received anti-PD-1 treatment were enrolled in the study.Baseline and time-serial stool samples were analyzed using 16S ribosomal RNA gene sequencing.Tumor responses,patient progression-free survival,and overall survival were used to measure clinical outcomes.Results:The diversities of the baseline gut microbiota were similar between responders(n=23)and nonresponders(n=19).The relative abundances of the Akkermansiaceae,Enterococcaceae,Enterobacteriaceae,Carnobacteriaceae and Clostridiales Family XI bacterial families were significantly higher in the responder group.These 5 bacterial families acted as a commensal consortium and better stratified patients according to clinical responses(P=0.014).Patients with a higher abundance of commensal microbes had prolonged PFS(P=0.00016).Using multivariable analysis,the abundance of the commensal consortium was identified as an independent predictor of anti-PD-1 immunotherapy in thoracic neoplasms(hazard ratio:0.17;95%confidence interval:0.05–0.55;P=0.003).Conclusions:Baseline gut microbiota may have a critical impact on anti-PD-1 treatment in thoracic neoplasms.The abundance of gut commensal microbes at diagnosis might be useful for the early prediction of anti-PD-1 immunotherapy responses. | Huihui Yin Lu Yang Gongxin Peng Ke Yang Yuling Mi Xingsheng Hu Xuezhi Hao Yuchen Jiao Xiaobing Wang Yan Wang | 2021 | Cancer Biology & Medicine2021，18，4： | 0 |
| 20 | Meristem Biology Flourishes Under Mt. Tai显示文摘 | Yuling Jiao Olivier Hamant Zhaojun Ding Xian Sheng Zhang | 2016 | Molecular Plant2016，9，8： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员