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| 1 | Prevalence of Autism Spectrum Disorder in China:A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years显示文摘This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children. | Hao Zhou Xiu Xu Weili Yan Xiaobing Zou Lijie Wu Xuerong Luo Tingyu Li Yi Huang Hongyan Guan Xiang Chen Meng Mao Kun Xia Lan Zhang Erzhen Li Xiaoling Ge Lili Zhang Chunpei Li Xudong Zhang Yuanfeng Zhou Ding Ding Andy Shih Eric Fombonne Yi Zheng Jisheng Han Zhongsheng Sun Yong-hui Jiang Yi Wang LATENT-NHC Study Team | 2020 | Neuroscience Bulletin2020，36，9： | 158 |
| 2 | A novel method for purification of recombinant adeno-associated virus vectors on a large scale显示文摘A novel method for recombinant adeno-associ-ated virus (rAAV) purification on large scale is described. The method involves three steps, including chloroform treatment, PEG/NaCl precipitation and chloroform extraction. The whole procedure can be performed in four hours. Using this purification method, we can reproducibly obtain, from 4 × 109 of proviral cells cultured in roller bottles, purified rAAV-GFP stocks with titers of around 5×1013 particles/mL and purity greater than 95%. The infectious titers of the vector stocks were up to 2×1012 TU/mL, thus particle-to-infectivity rate was about 25. Under an electronic microscope, most rAAV particles appeared full and a few were in intermediate form. Empty particles were rarely seen. The purified rAAV-GFP stocks have been successfully used in in vitro and in vivo transfection experiments. Therefore, this new method offers a simple, rapid and cost-effective way for large-scale rAAV purification. | WU Xiaobing DONG Xiaoyan WU Zhijian CAO Hui NIU Dongbin QU Jianguo WANG Hong HOU Yunde | 2001 | Chinese Science Bulletin2001，46，6： | 21 |
| 3 | Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment显示文摘Tumor cells along with a small proportion of cancer stem cells exist in a stromal microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells and extracellular components.Recent epidemiological and clinical studies strongly support that vitamin D supplementation is associated with reduced cancer risk and favorable prognosis. Experimental results suggest that vitamin D not only suppresses cancer cells, but also regulates tumor microenvironment to facilitate tumor repression. In this review, we have outlined the current knowledge on epidemiological studies and clinical trials of vitamin D. Notably, wesummarized and discussed the anticancer action of vitamin D in cancer cells, cancer stem cells and stroma cells in tumor microenvironment, providing a better understanding of the role of vitamin D in cancer. We presently re-propose vitamin D to be a novel and economical anticancer agent. | Xu Wu Wei Hu Lan Lu Yueshui Zhao Yejiang Zhou Zhangang Xiao Lin Zhang Hanyu Zhang Xiaobing Li Wanping Li Shengpeng Wang Chi Hin Cho Jing Shen Mingxing Li | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 20 |
| 4 | Soil Bacterial Communities Under Different Long-Term Fertilization Regimes in Three Locations Across the Black Soil Region of Northeast China显示文摘Although soil bacteria play critical roles in agro-ecosystems, the knowledge of their response to long-term fertilization across the black soil region of Northeast China is limited. In this study, we sequenced 16 S rRNA genes to assess the effects of four long-term fertilization regimes—non-fertilization(NoF), chemical fertilizer(CF), manure(M), and chemical fertilizer plus manure(CFM)—on soil properties and bacterial communities in three locations, the northern, middle, and southern parts, across the black soil region. Results showed that the influence of fertilization regimes on soil properties varied significantly among the three locations. Manure fertilization significantly increased microbial biomass carbon and relative abundance of copiotrophic bacteria. Principal component analysis(PCA)showed that the total bacterial communities were separated into three groups according to the sampling location despite long-term fertilization, and that soil pH was the most important factor in shifting bacterial communities. In addition, similar fertilization regimes resulted in different influences on bacterial community composition, and the most influential soil properties varied among the three locations. Our results highlighted that geographical separation was a more dominant factor affecting bacterial communities than fertilization, and that long-term similar fertilization regimes did not induce consistent changes in bacterial community composition in the black soil region. | HU Xiaojing LIU Junjie WEI Dan ZHU Ping CUI Xi'an ZHOU Baoku CHEN Xueli JIN Jian LIU Xiaobing WANG Guanghua | 2018 | Pedosphere2018，28，5： | 17 |
| 5 | Estimation of carbon sinks in chemical weathering in a humid subtropical mountainous basin显示文摘The fluvial geochemistry of the mainstream and tributaries of the Zengjiang River was investigated,and the mass balance approach and deduction methods were used to estimate the uptake of atmospheric CO2 through rock chemical weathering.The results showed that the chemical runoff mainly consisted of HCO3-,Ca2+,Na+,and dissolved Si,and that silicate mineral weathering was significant,but carbonate mineral weathering was a minor source of dissolved loads in the Zengjiang River basin because of the low amount of interlayered carbonate rock strata in the catchment.The ion composition indicated that atmospheric CO2 was the primary erosive agent for rock chemical weathering in the Zengjiang River basin.The CO2 consumption fluxes caused by rock chemical weathering were(3.50-3.81) × 105 mol km-2 a-1,which is just lower than that in tropical and subtropical basalt and carbonate regions,and is much higher than that in temperate and cold-temperate regions,indicating that surficial chemical weathering processes in the humid and hot monsoon current influencing the low-middle latitude zone of the Northern Hemisphere constitutes a significant carbon sink in the global biogeochemical cycle. | TAO Zhen GAO QuanZhou WANG ZhenGang ZHANG ShengHua XIE ChenJi LIN PeiSong RUAN XiaoBing LI ShuHong MAO HaiRuo | 2011 | Chinese Science Bulletin2011，56，35： | 15 |
| 6 | Paleo-Tethyan Oceanic Crust Subduction in the Eastern Section of the East Kunlun Orogenic Belt:Geochronology and Petrogenesis of the Qushi'ang Granodiorite显示文摘The Qushi'ang granodiorite(QSG) is located at the central east of the ophiolitic melange belt in the East Kunlun Orogenic Belt(EKOB) in the northern margin of the Qinghai-Tibetan Plateau. LA-MC-ICP-MS zircon U–Pb dating suggests that the granodiorite and mafic microgranular enclaves(MMEs) crystallized 246.61±0.62 and 245.45±0.9 Ma ago, respectively. Granodiorite, porphyritic diorite, and MMEs are metaluminous and medium-K calk-alkaline series, with island-arc magma features, such as LILE enrichment and HFSE depletion. The porphyritic diorite has high Cr(13.50 ppm to 59.01 ppm), Ni(228.53 ppm to 261.29 ppm), and Mg~#(46–54). Granodiorite and porphyritic diorite have similar mineral compositions and evolved major and trace elements contents, particularly Cr and Ni, both of which are significantly higher than that in granites of the same period. The crystallization age of MMEs is close to that of granodiorite, and their major and trace elements contents are in-between porphyritic diorite and granodiorite. The results suggest that the original mafic magma, which was the product of mantle melting by subduction process, intruded into the lower crust(Kuhai Rock Group), resulting in the formation of granodiorite. Countinous intrusion of mafic magma into the unconsolidated granodiorite formed MMEs and porphyritic diorite. The granodiorite reformed by late-stage strike-slip faulting tectonic event indicates that the strike-slip fault of Middle Kunlun and the collision of the Bayanhar block with East Kunlun were later than 246 Ma. Therefore, the formation of the QSG not only indicates the critical period of evolution of East Kunlun but also represents the tectonic transition from oceanic crust subduction to slab breaking. | CHEN Guochao PEI Xianzhi LI Ruibao LI Zuochen LIU Chengjun CHEN Youxin PEI Lei WANG Meng LI Xiaobing | 2017 | Acta Geologica Sinica(English Edition)2017，91，2： | 14 |
| 7 | Growth and Common Prosperity in China显示文摘This paper introduces a decomposition method that quantifies the contributions to common prosperity of labor market performance and social policies and extends the idea of shared prosperity to a new measure of inequity in opportunities.The resulting common prosperity indices and opportunity equality indices are then applied to five waves of the Chinese Household Income Project data from 1988 to 2018.This paper shows that the labor market performance and social policies have been improving over the last 30 years and have helped China move towards common prosperity for everyone.The indices developed in this paper allow us to quantify the extent of shared prosperity that a country has achieved and to carry out empirical studies on which policy is working and which is not.It can also help us identify the fundamental causes of inequality and aid us in achieving equality in opportunity among all members of society. | Nanak Kahwani Xiaobing Wang Ning Xue Peng Zhan | 2022 | China & World Economy2022，30，1： | 13 |
| 8 | High-accuracy primary and transfer standards for radiometric calibration显示文摘The first research and experimental results obtained in China of high-accuracy radiometric calibration based on cryogenic radiometer are reported. Uncertainties of cryogenic radiometer and trap detectors at 7 wavelengths in the visible spectrum (488-786 nm) were less than 0.023% and 0.035% respectively, which proved the reasonability and possibility of establishing and transferring high-accuracy radiometric standards based on detectors. | Xiaobing Zheng Haoyu Wu Junping Zhang Yucheng Liu Wei Zhou Leyi Wang Yanli Qiao | 2000 | Chinese Science Bulletin2000，45，21： | 12 |
| 9 | Gold nanorod-photosensitizer conjugate with extracellular pH-driven tumor targeting ability for photothermal/photodynamic therapy显示文摘氯 e6-pHLIP <候补选手class=“ a-plus-plus ”> ss -AuNRs,金使nanorod具有感光性结合包含 pH (低)有给予细胞外的 pH 的一张二硫化物契约的插入肽( pHLIP )( pH <候补选手class=“ a-plus-plus ”> e )-driven 肿瘤指向能力,成功地为光力学的 bimodal 和 photothermal 治疗被开发了。在这 bimodal 治疗,氯 e6 (Ce6 ) ,第二代的 photosensitizer (PS ) ,被用于光力学的治疗(太平洋夏季时间) 。金 nanorods (AuNRs ) 作为 Ce6 的 nanocarrier 和 quencher 为 photothermal 治疗(PTT ) 并且也被用作一个过高热代理人。pHLIPss 作为一根驾驶 pHe 的指向探针被设计在低 pH 在癌症房间提高 Ce6 和 AuNRs 的累积。在 Ce6-pHLIP < 潜水艇 class= “ a-plus-plus ” > ss -AuNRs, Ce6 接近并且由 AuNRs 熄灭了,引起小太平洋夏季时间效果。当暴露了到正常生理的 pH 时 7.4, Ce6-pHLIP < 潜水艇 class= “ a-plus-plus ” > ss -AuNRs 泛泛地与房间膜联系。然而,曾经暴露了到酸的 pH 6.2, pHLIP 活跃地插入到房间膜,和 conjugates 是进房间的 translocated。当这发生时, Ce6 由于二硫化物与 AuNRs 分开细胞内部的谷胱甘肽(GSH ) 引起的契约劈开,和汗衫氧在光之上为太平洋夏季时间被生产照耀。作为单个 PTT 代理人,另外, AuNRs 能由提高的浸透和保留(EPR ) 效果在肿瘤提高 PS 的累积。因此由我们的数据显示了当暴露了到酸的 pH 时, Ce6-pHLIP < 潜水艇 class= “ a-plus-plus ” > ss -AuNRs 能为癌症治疗完成 synergistic PTT/PDT bimodality。 | Nannan Wang Zilong Zhao Yifan Lv Huanhuan Fan Huarong Bai Hongmin Meng Yuqian Long Ting Fu Xiaobing Zhang Weihong Tan | 2014 | Nano Research2014，7，9： | 11 |
| 10 | Characteristic Rainfall for Warning of Debris Flows显示文摘A characteristic rainfall is introduced to overcome the difficulties encountered in determining a critical rainfall value for triggering debris flow.The characteristic value is defined as the rainfall at which debris-flow occurrence probability shows a rapid increase,and can be used as a warning rainfall threshold for debris flows.Investigation of recorded debris flows and 24-hour rainfall data at Jiangjia basin,Yunnan Province,in southwestern China,demonstrates the existence of such a characteristic rainfall.It was found that the characteristic rainfall corresponds to the daily rainfall of 90% cumulative probability by analyzing the basin's daily rainfall histogram.The result provides a simple and useful method for estimating a debris-flow warning rainfall threshold from the daily rainfall distribution.It was applied to estimate the debris-flow warning rainfall threshold for the Subaohe basin,a watershed in the 2008 Wenchuan earthquake zone with many physical characteristics similar to those of the Jiangjia basin. | HU Kaiheng Cui Peng Wang Chuanchang Li Yong Lu Xiaobing | 2010 | Journal of Mountain Science2010，7，3： | 11 |
| 11 | TNF-α suppresses sweat gland differentiation of MSCs by reducing FTO-mediated m^6 A-demethylation of Nanog mRNA显示文摘An effect of inhibition of tumor necrosis factor-α(TNF-α)on differentiation of mesenchymal stromal cells(MSCs)has been demonstrated,but the exact mechanisms that govern MSCs differentiation remain to be further elucidated.Here,we show that TNF-αinhibits the differentiation of MSCs to sweat glands in a specific sweat gland-inducing environment,accompanied with reduced expression of Nanog,a core pluripotency factor.We elucidated that fat mass and obesity-associated protein(FTO)-mediated m^6 A demethylation is involved in the regulation of MSCs differentiation potential.Exposure of MSCs to TNF-αreduced expression of FTO,which demethylated Nanog m RNA.Reduced expression of FTO increased Nanog m RNA methylation,decreased Nanog m RNA and protein expression,and significantly inhibited MSCs capacity for differentiation to sweat gland cells.Our finding is the first to elucidate the functional importance of m^6 A modification in MSCs,providing new insights that the microenvironment can regulate the multipotency of MSCs at the post-transcriptional level.Moreover,to maintain differentiation capacity of MSCs by regulating m^6 A modification suggested a novel potential therapeutic target for stem cellmediated regenerative medicine. | Yihui Wang Rui Wang Bin Yao Tian Hu Zhao Li Yufan Liu Xiaoli Cui Liuhanghang Cheng Wei Song Sha Huang Xiaobing Fu | 2020 | Science China(Life Sciences)2020，63，1： | 9 |
| 12 | Experimental investigation and modeling of flotation column for treatment of oily wastewater显示文摘A unique cyclonic static microbubble flotation column was developed for oily wastewater separation.The separation effciency was found to be highly dependent on gas holdup and bubble size distribution.By changing the circulation pressure,gas flow rate,frother concentration,the effect of operation parameters on gas holdup and oil removal effciency were attained.A mathematical modeling between the kinetic constant and the gas holdup was established for oily water separation process.The results show that higher gas holdup and smaller microbubble sizes are benefcial to improve oil removal effciency. | Ran Jincai Liu Jiongtian Zhang Chunjuan Wang Dengyue Li Xiaobing | 2013 | International Journal of Mining Science and Technology2013，23，5： | 9 |
| 13 | Effects of long-term fertilizer applications on peanut yield and quality and plant and soil heavy metal accumulation显示文摘The status of essential and potentially toxic trace elements in soils and crops can be affected by long-term fertilization practices. This study aimed to investigate changes in peanut (Arachis hypogaea L.) yield and kernel quality, and changes in copper (Cu), zinc (Zn), lead (Pb), and cadmium (Cd)concentrations in soil and peanut kernels after 16 years of continuous cropping with different fertilization treatments. Five fertilization treatments were applied at a red soil site in Southeast China:chemical fertilizer (F) containing nitrogen, phosphorus, and potassium, F+trace elements (FT), pig manure (M), M+effective microorganisms (MB), and MB+trace elements (MBT). Properties of soil and pig manure, heavy metal contents in soil and peanut kernels, and the compositions of amino and fatty acids in kernels were determined. Application of pig manure significantly increased peanut biomass, kernel yield, and crude protein and total amino acid contents in kernels, but led to higher amounts of Cu, Zn, and Cd in soil and higher amounts of Zn and Cd in peanut kernels compared with that of chemical fertilizer. There should be greater concern about potential kernel Cd and Zn contaminations resulting from long-term application of pig manure contaminated with potentially toxic metals as an organic fertilizer. | Xiaobing WANG Wuxing LIU Zhengao LI Ying TENG Peter CHRISTIE Yongming LUO | 2020 | Pedosphere2020，30，4： | 9 |
| 14 | Percent free prostate-specific antigen for prostate cancer diagnosis in Chinese men with a PSA of 4.0-10.0 ng/mL:Results from the Chinese Prostate Cancer Consortium显示文摘Objective:To test the diagnostic performance of percent free prostate-specific antigen(%fPSA)in predicting any prostate cancer(PCa)and high-grade prostate cancer(HGPCa)in a retrospective multi-center biopsy cohort with a PSA level of 4.0e10.0 ng/mL in China.Methods:Consecutive patients with a PSA of 4.0-10.0 ng/mL who underwent transrectal ultrasound-guided biopsy were enrolled at 16 Chinese medical centers from January 1st,2010 to December 31st,2013.Total and free serum PSA determinations were performed using three types of electro-chemiluminescence immunoassays recalibrated to the World Health Organization(WHO)standard.The diagnostic accuracy of PSA,%fPSA,and %fPSA in combination with PSA(%fPSA t PSA)was determined using the area under the receiver operating characteristic(ROC)curve(AUC).Results:A total of 2310 consecutive men with PSA levels between 4.0 and 10.0 ng/mL were included,and the detection rate of PCa was 25.1%.The AUC of%fPSA and %fPSA t PSA in predicting any PCa was superior to PSA alone in men aged≥60 years(0.623 vs.0.534,p<0.0001)but not in men aged 40e59 years(0.517 vs.0.518,p=0.939).Similar result was yield in predicting HGPCa.Conclusion:In a clinical setting of Chinese men with 4.0e10.0 ng/mL PSA undergoing initial prostate biopsy,adding %fPSA to PSA can moderately improve the diagnostic accuracy for any PCa and HGPCa compared with PSA alone in patients≥60 but not in patients aged 40-59 years. | Rui Chen Liping Xie Xiaobing Cai Yiran Huang Liqun Zhou Lulin Ma Xu Gao Chuanliang Xu Shancheng Ren Pengfei Shao Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Li Lu Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tie Zhou Fubo Wang Biming He Yinghao Sun | 2015 | Asian Journal of Urology2015，2，2： | 8 |
| 15 | Gender and Off-farm Employment: Evidence from Rural China显示文摘现在的纸的目标是检验从 2000 的经济的扩大怎么影响了农村离开农场劳动市场参予。明确地,我们寻求决定离开农场劳动是否在 2000 以后增加了,什么雇用的形式并且是否在离开农场劳动正在驾驶趋势性差别能在离开农场雇用趋势被观察。用全国地代表性的数据集由在六个省在 2000 和 2008 进行的调查的二个波浪组成,这份报纸发现那离开农场劳动市场参予继续在 2000 年代初稳定地起床。然而,在在 2000 前后与职业选择联系的趋势有清楚的差别。另外,我们发现农村离开农场雇用趋势为男人和女人是不同的。我们的分析也证明挣工资的雇用的上升与增加相应为男人和女人的不熟练的工资。 | Xiaobing Wang Linghui Han Jikun Huang Linxiu Zhang Scott Rozelle | 2016 | China & World Economy2016，24，3： | 8 |
| 16 | Current status and future of acid rain in China显示文摘As a part of the national key project of acid rain research, chemical element analysis of rainwater has been carried out based on observation of acid rain network in Chinese MeteorologicalAdministration over the years of 1992 and 1993. Samples of precipitation collected from eachacid rain station were taken according to the standard established by Chinese MeteorologicalAdministration. pH value was measured with pH meter (accuracy of 0. 01) made in | DING Guo’an, XU Xiaobing, FANG Xiumei, JIN Shaping, XU Xia, Tang Jie, LIU Qijun, WANG Shufeng and WANG Wenxing1. Chinese Academy of Meteorological Sciences, Beijing 100081, China 2. Chinese Academy of Environment Sciences, Beijing 100012, China | 1997 | Chinese Science Bulletin1997，42，24： | 8 |
| 17 | Modifying the Autism Spectrum Rating Scale(6–18 years)to a Chinese Context:An Exploratory Factor Analysis显示文摘The purpose of this study was to explore the psychometric properties of the Chinese version of the autism spectrum rating scale(ASRS). We recruited 1,625community-based children and 211 autism spectrum disorder(ASD) cases from 4 sites, and the parents of all participants completed the Chinese version of the ASRS. A robust weighted least squares means and variance adjusted estimator was used for exploratory factor analysis. The3-factor structure included 59 items suitable for the current sample. The item reliability for the modi?ed Chinese version of the ASRS(MC-ASRS) was excellent. Moreover,with 60 as the cut-off point, receiver operating characteristic analysis showed that the MC-ASRS had excellent discriminate validity, comparable to that of the unmodi?ed Chinese version(UC-ASRS), with area under the curve values of 0.952(95% CI: 0.936–0.967) and 0.948(95% CI:0.930–0.965), respectively. Meanwhile, the con?rm factor analysis revealed that MC-ASRS had a better construct validity than UC-ASRS based on the above factor solution in another children sample. In conclusion, the MC-ASRS shows better ef?cacy in epidemiological screening for ASD in Chinese children. | Hao Zhou Lili Zhang Xuerong Luo Lijie Wu Xiaobing Zou Kun Xia Yimin Wang Xiu Xu Xiaoling Ge Yong-Hui Jiang Eric Fombonne Weili Yan Yi Wang | 2017 | Neuroscience Bulletin2017，33，2： | 8 |
| 18 | Ultrasound-triggered release of sinoporphyrin sodium from liposome-microbubble complexes and its enhanced sonodynamic toxicity in breast cancer显示文摘把超声(美国) 用于药交货和疾病治疗是重要工作。Sonodynamic 治疗(SDT ) 用在许多肿瘤的美国和一项 sonosensitizerexhibits antineoplastic 活动的全面治疗。在这研究,我们调查了使用新 sonosensitizer 的可行性(sinoporphyrin 钠, DVDMS ) 作为一个可能的候选人装进 liposome-microbubble 建筑群(DLMB ) 对乳癌提高 SDT。DLMB 经由 biotin 卵白素连接被综合并且证实了有好美国反应。导致美国的成穴起了一个关键作用从 DLMB 触发一个增加的收费载重版本并且改进细胞的举起和 DVDMS 的 intratumoral 散开认识到更好的 SDT 效果。DLMB 和美国治疗的联合在 vitro 导致了房间形态学,线粒体损坏,和房间 apoptosis 的重要变化。在 vivo,联合治疗显著地禁止了肿瘤生长,它看起来源于增加的 apoptosis 并且减少了增长活动。DLMB 正美国的 antitumor 效果的重要增加作为一条新途径建议他们的潜在的使用对乳癌支持 SDT 的杀死的活动。 | Yixiang Li Huanxiao An Xiaobing Wang Pan Wang Fei Qu Yan Jiao Kun Zhang Quanhong Liu | 2018 | Nano Research2018，11，2： | 8 |
| 19 | Fabrication,microstructure,and properties of SiC/Al4SiC4 multiphase ceramics via an in-situ formed liquid phase sintering显示文摘The SiC/Al4SiC4 composites with the improved mechanical properties and thermal conductivity were fabricated by the in-situ reaction of polycarbosilane(PCS)and Al powders using spark plasma sintering.The addition of 5 wt%yttrium(Y)sintering additive was useful to obtain fully dense samples after sintering at a relatively low temperature of 1650℃,due to the formation of a liquid phase during sintering.The average particle size of the in-situ formed SiC was^300 nm.The fracture toughness(4.9 MPa·m1/2),Vickers hardness(16.3 GPa),and thermal conductivity(15.8 W/(m·K))of the SiC/Al4SiC4 composite sintered at 1650℃were significantly higher than the hardness(13.2 GPa),fracture toughness(2.16 MPa·m1/2),and thermal conductivity(7.8 W/(m·K))of the monolithic Al4SiC4 ceramics.The improved mechanical and thermal properties of the composites were attributed to the high density,fine grain size,as well as the optimized grain boundary structure of the SiC/Al4SiC4 composites. | Junwen LIU Xiaobing ZHOU Peter TATARKO Qin YUAN Lan ZHANG Hongjie WANG Zhengren HUANG Qing HUANG | 2020 | Journal of Advanced Ceramics2020，9，2： | 7 |
| 20 | Effect of a thermokarst lake on soil physical properties and infiltration processes in the permafrost region of the Qinghai-Tibet Plateau, China显示文摘Changes in the hydrological processes in alpine soil constitute one of the several key problems encountered with studying watershed hydrology and ecosystem stability against the background of global warming. A typically developing thermokarst lake was chosen as a subject for a study using model simulation based on observations of soil physical properties, infiltration processes, and soil moisture. The results showed that the selected thermokarst lake imposed certain changes on the soil infiltration processes and, with the degree of impact intensifying, the initial infiltration rate decreased. The greatest reduction was achieved in the area of moderate impact. However, the stable infiltration rate and cumulative infiltration gradually increased in the surface layer at a depth of 10 and 20 cm, both decreasing initially and then increasing, which is correlated significantly with soil textures. Moreover, the cumulative infiltration changed in line with steady infiltration rate. Based on a comparative analysis, the Horton model helps better understand the effect on the soil infiltration processes of the cold alpine meadow close to the chosen thermokarst lake. In conclusion, the formation of the thermokarst lake reduced the water holding capacity of the alpine meadow soil and caused the hydraulic conductivity to increase, resulting in the reduction of runoff capacity in the area of the thermokarst lake. | WANG YiBo GAO ZeYong WEN Jing LIU GuoHua GENG Di LI XiaoBing | 2014 | Science China Earth Sciences2014，57，10： | 7 |
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