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| 1 | Developmental dysplasia of the hip: What has changed in the last 20 years?显示文摘Developmental dysplasia of the hip(DDH) describes the spectrum of structural abnormalities that involve the growing hip. Early diagnosis and treatment is critical to provide the best possible functional outcome. Persistence of hip dysplasia into adolescence and adulthood may result in abnormal gait, decreased strength and increased rate of degenerative hip and knee joint disease. Despite efforts to recognize and treat all cases of DDH soon after birth, diagnosis is delayed in some children, and outcomes deteriorate with increasing delay of presentation. Different screening programs for DDH were implicated. The suspicion is raised based on a physical examination soon after birth. Radiography and ultrasonography are used to confirm the diagnosis. The role of other imaging modalities, such as magnetic resonance imaging, is still undetermined; however, extensive research is underway on this subject. Treatment depends on the age of the patient and the reducibility of the hip joint. At an early age and up to 6 mo, the main treatment is an abduction brace like the Pavlik harness. If this fails, closed reduction and spica casting is usually done. After the age of 18 mo, treatment usually consists of open reduction and hip reconstruction surgery. Various treatment protocols have been proposed. We summarize the current practice for detection and treatment of DDH, emphasizing updates in screening and treatment during the last two decades. | Pavel Kotlarsky Reuben Haber Victor Bialik Mark Eidelman | 2015 | World Journal of Orthopedics2015，6，11： | 52 |
| 2 | A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value显示文摘 | Changsong Zou Aojun Chen Lihong Xiao Heike M Muller Peter Ache Georg Haberer Meiling Zhang Wei Jia Ping Deng Ru Huang Daniel Lang Feng Li Dongliang Zhan Xiangyun Wu Hui Zhang Jennifer Bohm Renyi Liu Sergey Shabala Rainer Hedrich Jian-Kang Zhu Heng Zhang | 2017 | Cell Research2017，27，11： | 22 |
| 3 | Overview of HIV drug resistance and its implications for China显示文摘 | Maria Au Jessica Haberer | 2006 | Chinese Medical Journal2006，，23： | 15 |
| 4 | 危险度评价最新进展显示文摘在过去的几十年里 ,人们开发了许多新的方法来改进化学品危险度评价中的剂量 反应关系的评定 :如采用定义较为完善的有效作用剂量来替代无可见有害作用水平(NOAEL) ,以及改进了的不确定 /安全系数的评定方法。本文将介绍目前国际上使用较为广泛的几种评定方法 :①采用剂量 反应关系数学模拟的方法来估计有效剂量以取代NOAEL作为安全剂量的出发起点值的剂量 反应关系的评定方法 ,包括 :“基准剂量法”和“分类回归法” ;②使用种系内和种系间毒代动力学和毒效动力学的资料来选择不确定系数的“基于数据的不确定系数法” ;③用于估计不确定系数的可信区间 ,以及计算安全剂量值的可信区间的“概率参考剂量法”。 | 赵启宇 阚海东 Lynne HABER 陈秉衡 Michael DOURSON | 2004 | 中国药理学与毒理学杂志2004，18，2： | 15 |
| 5 | Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation显示文摘AIM: To investigate over-expression of Osteopontin(OPN) pathway expression and mechanisms of action in human alcoholic liver disease(ALD), in vivo and in vitro acute alcohol models. METHODS: OPN pathway was evaluated in livers from patients with progressive stages of human ALD and serum from drinkers with and without liver cirrhosis. In vitro stellate LX2 cells exposed to acute alcohol and in vivo in acute alcoholic steatosis mouse models were also investigated for OPN pathway expression and function. WT and OPN-/- mice were administered an acute dose of alcohol and extent of liver injury was examined by histopathology and liver biochemistry after 16-24 h. The causative role of OPN was studied in OPN knockout animals and in vitro in stellate LX2 cells, utilizing siRNA, aptamer and neutralizing antibodies to block OPN and OPN pathway. OPN pathway expression and downstream functional consequences were measured for signaling by Western blotting, plasmin activation by spectrophotometric assays and cell migration by confocal imaging and quantitation. RESULTS: OPN expression positively correlated with disease severity in patients with progressive stages of ALD. In vivo, associated with alcoholic steatosis, a single dose of acute alcohol significantly increased hepatic OPN mRNA and protein, and a cleaved OPN form in a dose dependent manner. OPN mRNA and secreted OPN also increased in parallel with activation of LX2 stellate cells within 4 h of a single dose of alcohol. Expression of OPN receptors, αvβ3-integrin and CD44, increased in human ALD, and in vivo and in vitro with alcohol administration. This was accompanied by downstream phosphorylation of Akt and Erk, increased mRNA expression of several fibrogenesis, fibrinolysis and extracellular matrix pathway genes, plasmin activation and hepatic stellate cell(HSC) migration. Inhibition of OPN and OPN-receptor mediated signaling partially inhibited alcohol-induced HSC activation, plasmin activity and cell migration. CONCLUSION: OPN is a key mediator of the alcoholinduced effects on hepatic stellate cell functions and liver fibrogenesis. | Devanshi Seth Alastair Duly Paul C Kuo Geoffrey W McCaughan Paul S Haber | 2014 | World Journal of Gastroenterology2014，20，36： | 5 |
| 6 | Robot‐assisted partial nephrectomy ( RAPN ) for completely endophytic renal masses: a single institution experience显示文摘 | Riccardo Autorino Ali Khalifeh Humberto Laydner Dinesh Samarasekera Emad Rizkala Remi Eyraud Robert J. Stein Georges‐Pascal Haber Jihad H. Kaouk | 2014 | BJU Int2014，，： | 3 |
| 7 | Reproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation显示文摘 | Elizabeth Montgomery Mary P Bronner John R Goldblum Joel K Greenson Marian M Haber John Hart Laura W Lamps Gregory Y Lauwers Audrey J Lazenby David N Lewin Marie E Robert Alicia Y Toledano Yu Shyr Kay Washington | 2001 | Human Pathology2001，，4： | 3 |
| 8 | The Combination of Ribavirin and Peginterferon Is Superior to Peginterferon and Placebo for Children and Adolescents With Chronic Hepatitis C显示文摘 | Kathleen B. Schwarz Regino P. Gonzalez–Peralta Karen F. Murray Jean P. Molleston Barbara A. Haber Maureen M. Jonas Philip Rosenthal Parvathi Mohan William F. Balistreri Michael R. Narkewicz Lesley Smith Steven J. Lobritto Stephen Rossi Alexandra Valsamaki | 2011 | Gastroenterology2011，，2： | 2 |
| 9 | Activation of Pancreatic Stellate Cells in Human and Experimental Pancreatic Fibrosis显示文摘 | Paul S. Haber Gregory W. Keogh Minoti V. Apte Corey S. Moran Nancy L. Stewart Darrell H.G. Crawford Romano C. Pirola Geoffrey W. McCaughan Grant A. Ramm Jeremy S. Wilson | 1999 | The American Journal of Pathology1999，，4： | 2 |
| 10 | 1997—2000年美国胆管闭锁患儿转归的一项多中心研究 | Shneider B.L. Brown M.B. Haber B. 郭战宏 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，0，A10： | 2 |
| 11 | Liver Transplantation in Management of Alveolar Echinococcosis: Two Case Reports显示文摘 | G. Moray R. Shahbazov S. Sevmis H. Karakayali A. Torgay G. Arslan N. Savas U. Yilmaz M. Haberal | 2009 | Transplantation Proceedings2009，，7： | 2 |
| 12 | Single-port urological surgery:single-center experience with the first 100 cases显示文摘 | White WM Haber GP Goel RK | 2009 | Urology2009，，04： | 2 |
| 13 | Outcomes of Robotic Partial Nephrectomy for Renal Masses With Nephrometry Score of ≥7显示文摘 | Michael A. White Georges-Pascal Haber Riccardo Autorino Rakesh Khanna Adrian V. Hernandez Sylvain Forest Bo Yang Fatih Altunrende Robert J. Stein Jihad H. Kaouk | 2011 | Urology2011，，4： | 2 |
| 14 | Robotic Versus Laparoscopic Partial Nephrectomy for Complex Tumors: Comparison of Perioperative Outcomes 显示文摘 | Jean-Alexandre Long Rachid Yakoubi Byron Lee Julien Guillotreau Riccardo Autorino Humberto Laydner Remi Eyraud Robert J. Stein Jihad H. Kaouk Georges-Pascal Haber | 2012 | European Urology2012，，： | 2 |
| 15 | Meta-Analysis of Retrograde Signaling in Arabidopsis thaliana Reveals a Core Module of Genes Embedded in Complex Cellular Signaling Networks显示文摘Plastid-to-nucleus 发信号为响应 environmentaland 的细胞的新陈代谢的协作和调整是必要的植物房间的发展暗示。许多运作后退表明小径被描述了被反应的氧种类,光合作用氧化还原作用不平衡, tetrapyrrole 中介,和 othermetabolic 特点要触发的那 arethought。这里,我们基于 transcriptome 和蛋白质相互作用数据报导元分析。比较 outputof 这些小径揭示在 operationalretrograde 发信号上侵犯的六不同来源刺激的公共和怪癖。我们的学习提供新奇卓见进这些小径的相互影响,支持当还未知的存在 ofan 基因的核心反应模块在测试的所有条件下面正在被调整。我们的分析进一步的 highlightsaffiliated 规章的 cis 元素并且分类 abscisic 酸并且作为涉及反应 cascadesfollowing 的第二等的部件的基于植物生长素的发信号一个 plastidial 信号。我们的学习提供结构的全球分析和不同小径 involvedin plastid-to-nucleus 在这建筑群上发信号和一个新看法的接口细胞的通讯 network.Key 词: | Christine GlaiBer Georg Haberer Iris Finkemeier Thomas Pfannschmidt Tatjana Kleine Dario Leister KarI-Josef Dietz Rainer Erich Haiusler Bernhard Grimm Klaus Franz Xaver Mayer | 2014 | Molecular Plant2014，7，7： | 2 |
| 16 | Per-oral endoscopic myotomy white paper summary显示文摘 | Stavros N. Stavropoulos David J. Desilets Karl-Hermann Fuchs Christopher J. Gostout Gregory Haber Haruhiro Inoue Michael L. Kochman Rani Modayil Thomas Savides Daniel J. Scott Lee L. Swanstrom Melina C. Vassiliou | 2014 | Surgical Endoscopy2014，，7： | 2 |
| 17 | 252 Robotic Partial Nephrectomies: Evolving Renorrhaphy Technique and Surgical Outcomes at a Single Institution显示文摘 | Jihad H. Kaouk Shahab P. Hillyer Riccardo Autorino Georges-Pascal Haber Tianming Gao Fatih Altunrende Rakesh Khanna Gregory Spana Michael A. White Humberto Laydner Wahib Isac Robert J. Stein | 2011 | Urology2011，，6： | 2 |
| 18 | Oxidative degradation of polyaromatic hydrocarbons catalyzed by blue laccase from Pleurotus ostreatus D1 in the presence of synthetic mediators显示文摘 | Natalia N. Pozdnyakova Janina Rodakiewicz-Nowak Olga V. Turkovskaya Jerzy Haber | 2006 | Enzyme and Microbial Technology2006，，6： | 2 |
| 19 | Mobile NMR for geophysical analysis and materials testing显示文摘Initiated by well logging NMR,portable NMR instruments are being developed for a variety of novel applications in materials testing,process analysis and control,which provides new opportunities for geophysical investigations.Small-diameter cylindrical sensors can probe short distances into the walls of slim-line logging holes,and single-sided sensors enable non-destructive testing of large objects.Both sensors are characterized by small sensitive volumes.Barrel-shaped magnets that accommodate the sample in their center have higher sensitivity due to a larger sensitive volume but can accommodate only samples like drill cores,which fit in size to the diameter of the magnet bore.Both types of magnets can be scaled down to the size of a coffee mug to arrive at sub-compact NMR equipment.Portable NMR magnets are reviewed in the context of applications related to geophysics. | BLüMICH Bernhard MAULER Jrg HABER Agnes PERLO Juan DANIELI Ernesto CASANOVA Federico | 2009 | Petroleum Science2009，6，1： | 2 |
| 20 | Electrophoretic motion of a charged spherical particle normal to a planar dielectric wall显示文摘 | Haber S | 1998 | Int J Multiphase Flow1998，24，5： | 1 |
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