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| 1 | Pancreatic cancer and its stroma: A conspiracy theory显示文摘Pancreatic cancer is characterised by a prominent desmoplastic/stromal reaction that has received little attention until recent times. Given that treatments focusing on pancreatic cancer cells alone have failed to significantly improve patient outcome over many decades, research efforts have now moved to understanding the pathophysiology of the stromal reaction and its role in cancer progression. In this regard, our Group was the first to identify the cells(pancreatic stellate cells, PSCs) that produced the collagenous stroma of pancreatic cancer and to demonstrate that these cells interacted closely with cancer cells to facilitate local tumour growth and distant metastasis. Evidence is accumulating to indicate that stromal PSCs may also mediate angiogenesis, immune evasion and the well known resistance of pancreatic cancer to chemotherapy and radiotherapy. This review will summarise current knowledge regarding the critical role of pancreatic stellate cells and the stroma in pancreatic cancer biologyand the therapeutic approaches being developed to target the stroma in a bid to improve the outcome of this devastating disease. | Zhihong Xu Srinivasa P Pothula Jeremy S Wilson Minoti V Apte | 2014 | World Journal of Gastroenterology2014，20，32： | 10 |
| 2 | A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment显示文摘 | Minoti V. Apte Jeremy S. Wilson Aurelia Lugea Stephen J. Pandol | 2013 | Gastroenterology2013，，6： | 6 |
| 3 | Disturbance Observer Based Speed Control of PMSM Using Fractional Order PI Controller显示文摘In this paper, fractional order PI(FOPI) control is developed for speed control of permanent magnet synchronous motor(PMSM). Designing the parameters for FOPI controller is a challenging task, especially for nonlinear systems like PMSM.All three PI controllers in the conventional vector controlled speed drive are replaced by FOPI controllers. Design of these FOPI controllers is based on the locally linearized model of PMSM around an operating point. This operating point changes with the load torque. The novelty of the work reported here is in use of Non Linear Disturbance Observer(NLDO) to estimate load torque to obtain this new operating point. All three FOPI controllers are then designed adaptively using this new operating point. The scheme is tested on simulation using MATLAB/SIMULINK and results are presented. | Aishwarya Apte Ujjwala Thakar Vrunda Joshi | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，1： | 5 |
| 4 | Numerical simulations of smoke movement from a pool fire in a ventilated tunnel显示文摘 | Flecher D F Kent J H Apte V B | 1994 | Fire SafJ1994，23，3： | 3 |
| 5 | Self-assembled vertically aligned gold nanorod super-lattices for ultra-high sensitive detection of molecules显示文摘我们显示出超点阵能作为探针或底层服务为的那自我装配的垂直地排列的金 nanorod (VA-GNRs ) 超离频各种各样的分子的敏感察觉。d葡萄糖和2,4,6强烈炸药( TNT )由于他们的很低的拉曼剖面图被选择了为模型系统( 5.6 佩?????汣獡????汰獵瀭畬???㈠?猯'T￣慮潮畴敢??????????????????????吗???????????????????￡???霔?? | Amey Apte Prashant Bhaskar Raja Das Smita Chaturvedi PankajPoddar Sulabha Kulkarni | 2015 | Nano Research2015，8，3： | 3 |
| 6 | Alcoholic pancreatitis:A tale of spirits and bacteria显示文摘Alcohol is a major cause of chronic pancreatitis.About5%of alcoholics will ever suffer from pancreatitis,suggesting that additional co-factors are required to trigger an overt disease.Experimental work has implicated lipopolysaccharide,from gut-derived bacteria,as a potential co-factor of alcoholic pancreatitis.This review discusses the effects of alcohol on the gut flora,the gut barrier,the liver-and the pancreas and proposes potential interventional strategies.A better understanding of the interaction between the gut,the liver and the pancreas may provide valuable insight into the pathophysiology of alcoholic pancreatitis. | Alain Vonlaufen Laurent Spahr Minoti V Apte Jean-Louis Frossard | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，2： | 3 |
| 7 | 基于风险性能评价的深部地质介质的核废物安全隔离方法(英文)显示文摘性能评价(PA)是风险评估在核废物地质处置领域中的应用。PA原是用作定量地展示处置场的工程与天然屏障性能的手段,其目的是最终证明处置系统的安全性。为此PA的最高指导思想是国际上公认的原则和指南。在实际应用中,PA与处置项目的几个主要部分都有联系,包括废物描述、处置概念到场址选择和描述。因此,PA在核废物管理项目中占有很特殊的位置:PA可以作为决策工具,辅助处置项目的计划和管理,使项目能够有效益地进行,以达到预期的目标。从自上而下的视角介绍PA,包括方法论、模式、处理不确定性等。还为中国科学家列出了一些具体的建议。 | 周玮 朱严斯台 Apted M J | 2007 | 岩石力学与工程学报2007，26，10： | 2 |
| 8 | Activation of Pancreatic Stellate Cells in Human and Experimental Pancreatic Fibrosis显示文摘 | Paul S. Haber Gregory W. Keogh Minoti V. Apte Corey S. Moran Nancy L. Stewart Darrell H.G. Crawford Romano C. Pirola Geoffrey W. McCaughan Grant A. Ramm Jeremy S. Wilson | 1999 | The American Journal of Pathology1999，，4： | 2 |
| 9 | A phase II trial of docetaxel and bevacizumab in recurrent ovarian cancer within 12 months of prior platinum-based chemotherapy显示文摘 | Robert M. Wenham James Lapolla Hui-Yi Lin Sachin M. Apte Johnathan M. Lancaster Patricia L. Judson Jesus Gonzalez-Bosquet Amber Herschberger Laura J. Havrilesky Angeles Alvarez Secord | 2013 | Gynecologic Oncology2013，，1： | 2 |
| 10 | Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis显示文摘 | Zhihong Xu Alain Vonlaufen Phoebe A. Phillips Eva Fiala-Beer Xuguo Zhang Lu Yang Andrew V. Biankin David Goldstein Romano C. Pirola Jeremy S. Wilson Minoti V. Apte | 2010 | The American Journal of Pathology2010，，5： | 2 |
| 11 | Determining Size-Specific Emission Factors for Environmental Tobacco Smoke Particles显示文摘 | Neil E. Klepeis Michael G. Apte Lara A. Gundel Richard G. Sextro William W. Nazaroff | 2003 | Aerosol Science and Technology2003，，10： | 2 |
| 12 | Reducing Treatment Burden in AMD显示文摘VEGF-A antagonists have revolutionized wet AMD treatment.Several challenges remain including high treatment burden requiring repeated intraocular injections for persistent disease.Brolucizumab directly inhibits VEGF-A function,providing visual outcomes comparable to aflibercept(an FDA-approved VEGF-A antagonist).Anatomic retinal outcomes including retinal fluid,a marker of disease activity,favored brolucizumab.To view this Bench to Bedisde,open or download the PDF. | Apte RS | 2020 | 四川生理科学杂志2020，42，2： | 2 |
| 13 | Periacinar stellate shaped cells in rat pancreas- identification,isolation,and culture显示文摘 | Apte MV Haber PS Applegate TL | 1998 | Gut1998，43，： | 1 |
| 14 | Managing soil carbon 显示文摘 | Lal R Griffin M Apt J | 2004 | Science2004，304，5669： | 1 |
| 15 | Comparative toxicity of anoparticulate ZnO,bulk ZnO,and ZnCl2 to a freshwater microalga(Pseudokirchneriella subcapitata);the importance of particle solubility显示文摘 | Franklin N M Rogers N J Apte S C | 2007 | Enviro nmentalScience and Technology2007，41，24： | 1 |
| 16 | Exacerbation of Acanthamoeba keratitis in animals treated with anti-macrophage inflammatory protein 2 or antineutrophil antibodies显示文摘 | Hurt M Apte S Leher H Howard K Niederkorn J Alizadeh H | 2001 | Infect Immun2001，69，： | 1 |
| 17 | Managing soil carbon显示文摘 | Lal R Griffin M Apt J | 2004 | Science2004，304，4： | 1 |
| 18 | Matrix metalloproteinases:old dogs and new tricks显示文摘 | Somerville RPT Oblander SA Apte SS | | 0，，： | 1 |
| 19 | Chronic pancreatitis : challenoges and advances in pathogenesis, genetiea, diagnosis and therapy 显示文摘 | Witt H Apte MV Keim V | 2007 | Gas- troenterology2007，132，4： | 1 |
| 20 | Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy 显示文摘 | La Spada APt Wilson EM Luhahn DB | 1991 | Nature1991，352，： | 1 |
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