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    题名 作者 年代 出处 被引量
1Intussusception in adults:Clinical characteristics,diagnosis and operative strategies显示文摘AIM:To evaluate 20 adults with intussusception and to clarify the cause, clinical features, diagnosis, and management of this uncommon entity.METHODS: A retrospective review of patients aged >18 years with a diagnosis of intestinal intussusception between 2000 and 2008. Patients with rectal prolapse, prolapse of or around an ostomy and gastroenterostomy intussusception were excluded. RESULTS: There were 20 cases of adult intussusception. Mean age was 47.7 years. Abdominal pain, nausea, and vomiting were the most common symptoms. The majority of intussusceptions were in the small intestine (85%). There were three (15%) cases of colonic intussusception. Enteric intussusception consisted of five jejunojejunal cases, nine ileoileal, and four cases of ileocecal invagination. Among enteric intussusceptions, 14 were secondary to a benign process, and in one of these, the malignant cause was secondary to metastatic lung adenocarcinoma. All colonic lesions were malignant. All cases were treated surgically. CONCLUSION: Adult intussusception is an unusual and challenging condition and is a preoperative diagnostic problem. Treatment usually requires resection of the involved bowel segment. Reduction can be attempted in small-bowel intussusception if the segment involved is viable or malignancy is not suspected; however, a more careful approach is recommended in colonic intussusception because of a significantly higher coexistence of malignancy.Savas Yakan Cemil Caliskan Ozer Makay Ali Galip Denecli Mustafa Ali Korkut 2009World Journal of Gastroenterology2009,15,16:12
2用于优化生产线及装配线的Andon系统显示文摘根据实际生产以及装配过程中出现的生产效率低下、故障率高等现象而提出一套简易的、本地化的解决方案。介绍了用于优化生产线及装配线的Andon系统设计,通过使用这个系统,不仅解决了生产效率低下的缺点,而且可对生产进行可视化管理,同时方便了工人的操作。SAVAS Tuemis 张文明 2007机电工程2007,24,5:10
3Listening to Turkish classical music decreases patients’anxiety,pain,dissatisfaction and the dose of sedative and analgesic drugs during colonoscopy:A prospective randomized controlled trial显示文摘AIM: To determine whether listening to music decreases the requirement for dosages of sedative drugs, patients’ anxiety, pain and dissatisfaction feelings during colonoscopy and makes the procedure more comfortable and acceptable. METHODS: Patients undergoing elective colonoscopy between October 2005 and February 2006 were randomized into either listening to music (Group 1, n = 30) or not listening to music (Group 2, n = 30). Anxiolytic and analgesic drugs (intravenous midazolam and meperidine) were given according to the patients’ demand. Administered medications were monitored. We determined their levels of anxiety using the State-Trait Anxiety Inventory Test form. Patients’ satisfaction, pain, and willingness to undergo a repeated procedure were self-assessed using a visual analog scale.RESULTS: The mean dose of sedative and analgesic drugs used in group 1 (midazolam: 2.1 ± 1.4, meperidine: 18.1 ± 11.7) was smaller than group 2 (midazolam: 2.4 ± 1.0, meperidine: 20.6 ± 11.5), but without a significant difference (P > 0.05). The mean anxiety level in group 1 was lower than group 2 (36.7 ± 2.2 vs 251.0 ± 1.9, P < 0.001). The mean satisfaction score was higher in group 1 compared to group 2 (87.8 ± 3.1 vs 58.1 ± 3.4, P < 0.001). The mean pain score in group 1 was lower than group 2 (74.1 ± 4.7 vs 39.0 ± 3.9, P < 0.001).CONCLUSION: Listening to music during colonoscopy helps reduce the dose of sedative medications, as well as patients’ anxiety, pain, dissatisfaction during the procedure. Therefore, we believe that listening to music can play an adjunctive role to sedation in colonoscopy. It is a simple, inexpensive way to improve patients’ comfort during the procedure.Nimet Ovayolu Ozlem Ucan Seda Pehlivan Yavuz Pehlivan Hakan Buyukhatipoglu M Cemil Savas Murat T Gulsen 2006World Journal of Gastroenterology2006,12,46:10
4Intraoperative acidosis is a new predictor for postoperative pancreatic fistula after pancreaticoduodenectomy显示文摘BACKGROUND:Early diagnosis of postoperative pancreatic fistula(POPF) is important for proper interventions.The preoperative,intraoperative and early postoperative biochemical markers have predictive value of POPF.The present study was to evaluate several simple biochemical parameters in the prediction of POPF.METHODS:Patients who underwent pancreaticoduodenectomy in our center between 2006 and 2015 were reviewed retrospectively.Preoperative and early postoperative biochemical parameters were evaluated.Additionally,the relationship between POPF and p H and lactate level at the end of surgery were analyzed,and neutrophil-to-lymphocyte ratio(NLR),plateletto-lymphocyte ratio(PLR),and red cell distribution widthto-platelet ratio(RPR) were calculated for postoperative days(PODs) 1 and 3.Diagnosis and grading of POPF were performed according to the standards of the International Study Group on Pancreatic Fistula.The patients were divided into two groups:Group 1 with no fistula or grade-A fistula; group 2 with grade-B or-C fistula.These simple biochemical markers were then compared between the two groups.RESULTS:Serum amylase level was significantly higher at POD3,and p H level was significantly lower at the end of operation in group 2 compared with those in group 1.However,the serum amylase was below the upper limit of normal serum level and therefore,the difference was not significant in clinical practice.Receiver operating charecteristic curve analysis showed that p H level was a reliable predictor of POPF(area under the curve:0.713; 95% CI:0.573-0.853).CONCLUSIONS:A low p H level at the end of pancreaticoduodenectomy was a risk factor of POPF.NLR,PLR,and RPR had no predictive value of POPF after pancreaticoduodenectomy.Erdem Kinaci Mert Mahsuni Sevinc Abdulkerim Ozakay Savas Bayrak Ekrem Cakar Serkan Sari 2016Hepatobiliary & Pancreatic Diseases International2016,15,3:7
5Leptin levels in the differential diagnosis between benign and malignant ascites显示文摘AIM: To evaluate the role of leptin levels in the differential diagnosis of ascites. METHODS: Ascitic leptin, TNFα and serum leptin levels were measured in 77 patients with ascites (35 with malignancies, 30 cirrhosis and 12 tuberculosis). Control serum samples were obtained from 20 healthy subjects. Leptin and TNFα levels were measured by ELISA. Body mass index (BMI) and percentage of body fat (BFM) by skin fold measurement were calculated for all patients and control groups. Peritoneal biopsy, ascites cytology and cultures or biochemical values were used for the diagnosis of patients. RESULTS: In patients with malignancies, the mean serum and ascites leptin levels and their ratios were significantly decreased compared to the other patient groups and controls. In tuberculosis peritonitis, ascitic fluid TNFα levels were significantly higher than malignant ascites and cirrhotic sterile ascites. BMI and BFM values did not distinguish between patients and controls. CONCLUSION: In patients with malignant ascites, levels of leptin and TNFα were significantly lower than in patients with tuberculous ascites.Mehmet Buyukberber Mehmet Koruk M Cemil Savas Murat T Gulsen Yavuz Pehlivan Rukiye Deveci Alper Sevinc Serdar Gergerlioglu 2007World Journal of Gastroenterology2007,13,3:7
6Primary glomerular diseases in the elderly显示文摘Primary glomerular diseases in the elderly population are a frustrating topic due to difficulties in both the diagnosis and decision making about treatment. The most frequent type of primary glomerular disease in elderly is membranous nephropathy; while its counterpart in younger population is Ig A nephropathy. The most frequent cause of nephrotic syndrome in the elderly is also membranous nephropathy. Pauci-immune crescentic glomerulonephritis(GN) rate increases both in elderly and very elderly population. Pauci-immune crescentic GNs should be regarded as urgencies in elderly patients as in their younger counterparts due to potential for causing end-stage renal disease in case of delayed diagnosis and treatment, and also causing mortality due to alveolar hemorrhage in patients with pulmonary involvement. Renal biopsy is the inevitable diagnostic method in the elderly as in all other age groups. Renal biopsy prevents unnecessary treatments and provides prognostic data. So advanced age should not be the sole contraindication for renal biopsy. The course of primary glomerular diseases may differ in the elderly population. Acute kidney injury is more frequent in the course and renal functions may be worse at presentation. These patients are more prone to be hypertensive. The decision about adding immune suppressive therapies to conservative methods should be made considering many factors like co-morbidities, drug side effects and potential drug interactions, risk of infection, patient preference, life expectancy and renal functions at the time of diagnosis.Abdullah Sumnu Meltem Gursu Savas Ozturk 2015World Journal of Nephrology2015,4,2:6
7Experimental investigation of cutting parameters in machining of 100Cr6 with tangential turn-milling method显示文摘Vedat Savas Cetin Ozay Hasan Ballikaya 2016Advances in Manufacturing2016,4,1:4
8Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis显示文摘AIM: To evaluate the therapeutic role of caffeic acid phenethyl ester (CAPE) in a rat model of ceruleaninduced acute pancreatitis (AP).METHODS: Seventy male Wistar albino rats were divided into seven groups. Acute edematous pancreatitis was induced by subcutaneous cerulein injection (20 μg/kg) four times at 1-h intervals. CAPE (30 mg/kg) was given by subcutaneous injection at the beginning (CAPE 1 group) and 12 h after the last cerulein injection (CAPE 2 group). Serum amylase, lipase, white blood cell count, and tumor necrosis factor (TNF)-α levels were measured, and pancreatic histopathology was assessed. RESULTS: In the AP group, amylase and lipase levels were found to be elevated and the histopathological evaluation showed massive edema and inflammation of the pancreas, with less fatty necrosis when compared with sham and control groups. Amylase and lipase levels and edema formation decreased signif icantly in the CAPE therapy groups (P < 0001); especially in the CAPE 2 group, edema was improved nearly completely (P = 0001). Inflammation and fatty necrosis were partially recovered by CAPE treatment. The pathologicalresults and amylase level in the placebo groups were similar to those in the AP group. White blood cell count and TNF-α concentration was nearly the same in the CAPE and placebo groups.CONCLUSION: CAPE may be useful agent in treatment of AP but more experimental and clinical studies are needed to support our observation of benef icial effects of CAPE before clinical usage of this agent.Mehmet Buyukberber M Cemil Savas Cahit Bagci Mehmet Koruk Murat T Gulsen Ediz Tutar Tugba Bilgic Nurdan  Ceylan 2009World Journal of Gastroenterology2009,15,41:4
9Portopulmonary hypertension in liver transplant candidates显示文摘Pulmonary vascular disorders including portopulmonary hypertension(PoPHT) are among the common complications of liver disease and are prognostically significant. Survival is very low without medical treatment and liver transplantation. With advances in medical therapy for elevated pulmonary artery pressure(PAP) and liver transplant surgery, survival of patients with Po PHT and advanced liver disease is significantly improved. Because of the prognostic significance of Po PHT and the limited donor pool, a comprehensive preoperative cardio-pulmonary assessment is of great importance in cirrhotic patients prior to transplant surgery. Therefore, a detailed transthoracic Doppler echocardiographic examination must be an essential component of this evaluation. Patients with mild Po PHT can safely undergo liver transplant surgery. In cases of moderate to severe Po PHT, right heart catheterization(RHC) should be performed. In patients with moderate to severe Po PHT on RHC(mean PAP 35-45 mm Hg), vasodilator therapy should be attempted. Liver transplantation should be encouraged in cases that demonstrate a positive response. Bridging therapy with specific pulmonary arterial hypertension treatment agents should be considered until the transplant surgery and should be continued during the peri- and post-operative periods as needed.Serife Savas Bozbas Huseyin Bozbas 2016World Journal of Gastroenterology2016,22,6:4
10Cerebral venous thrombosis presenting with headache only and misdiagnosed as subarachnoid hemorrhage显示文摘INTRODUCTION Patients with headache constitute up to 4.5%of emergency department(ED)visits.[1]Cerebral venous thrombosis(CVT)is an important cause of the headache that is more common than once suspected.The diagnosis of CVT is often missed or delayed because of non-Aslihan Yuruktumen Unal Ali Unal Erkan Goksu Savas Arslan 2016World Journal of Emergency Medicine2016,7,3:4
11A survey on temporal logics for specifying and verifying real-time systems显示文摘Savas KONUR 2013Frontiers of Computer Science2013,7,3:4
12奥氏体不锈钢在干切削和微量润滑条件下的切削力的研究显示文摘金属切削加工中冷却润滑液的使用会增加加工成本,污染环境,而干切削和近干切削可以彻底消除或极大地减少冷却润滑液的使用,所以其成为许多单位研究热点。近来奥氏体不锈钢在各行业内应用越来越广,为了充分了解奥氏体不锈钢的切削性能,本文对奥氏体不锈钢0Cr18Ni9在传统乳化剂、干车削和微量润滑车削条件下进行切削试验,通过设计多因素正交试验方法,建立压电式测力系统测量切削过程中的动态平均切削力,在不同的冷却润滑方式下,比较背吃刀量、切削速度、进给量等切削用量对切削力的影响,得出各个因素的影响曲线图,从而揭示奥氏体不锈钢0Cr18Ni9在车削过程中的切削力变化情况,为实际的生产加工积累和提供基础数据。Savas TUMIS 徐侠凯 吴小明 2009组合机床与自动化加工技术2009,,5:3
13Skin disorders in peritoneal dialysis patients:An underdiagnosed subject显示文摘AIM: To examine all skin changes in peritoneal dialysis(PD) patients followed up in our unit.METHODS: Patients on PD program for at least three months without any known chronic skin disease were included in the study. Patients with already diagnosed skin disease, those who have systemic diseases that may cause skin lesions, patients with malignancies and those who did not give informed consent were excluded from the study. All patients were examined by the same predetermined dermatologist with all findings recorded. The demographic, clinical and laboratory data including measures of dialysis adequacy of patients were recorded also. Statistical Package for Social Sciences(SPSS) for Windows 16.0 standard version was used for statistical analysis.RESULTS: Among the patients followed up in our PD unit, those without exclusion criteria who gave informed consent, 38 patients were included in the study with male/female ratio and mean age of 26/12 and 50.3 ± 13.7 years, respectively. The duration of CKD was 7.86 ± 4.16 years and the mean PD duration was 47.1 ± 29.6 mo. Primary kidney disease was diabetic nephropathy in 11, nephrosclerosis in six, uropathologies in four, chronic glomerulonephritis in three, chronic pyelonephritis in three, autosomal dominant polycystic kidney disease in three patients while cause was unknown in eight patients. All patients except for one patient had at least one skin lesion. Loss of lunula, onychomycosis and tinea pedis are the most frequent skin disorders recorded in the study group. Diabetic patients had tinea pedis more frequently(P = 0.045). No relationship of skin findings was detected with primary renal diseases, comorbidities and medications that the patients were using.CONCLUSION: Skin abnormalities are common in in PD patients. The most frequent skin pathologies are onychomycosis and tinea pedis which must not be overlooked.Meltem Gursu Sami Uzun Derya Topcuoglu Leyli Kadriye Koc Lamiye Yucel Abdullah Sumnu Egemen Cebeci Oktay Ozkan Ahmet Behlul Leyla Koc Savas Ozturk Rumeyza Kazancioglu 2016World Journal of Nephrology2016,5,4:3
14Computational and Empirical Investigation of Propeller Tip Vortex Cavitation Noise显示文摘In this study,non-cavitating and cavitating flow around the benchmark DTMB 4119 model propeller are solved using both viscous and potential based solvers.Cavitating and non-cavitating propeller radiated noises are then predicted by using a hybrid method in which RANS(Reynolds-averaged Navier-Stokes)and FWH(Ffowcs Williams Hawkings)equations are solved together in open water conditions.Sheet cavitation on the propeller blades is modelled by using a VOF(Volume of Fiuld)method equipped with Schnerr-Sauer cavitation model.Nevertheless,tip vortex cavitation noise is estimated by using two different semi-empirical techniques,namely Tip Vortex Index(TVI,based on potential flow theory)and Tip Vortex Contribution(TVC).As the reference distance between noise source and receiver is not defined in open water case for TVI technique,one of the outputs of this study is to propose a reference distance for TVI technique by coupling two semi-empirical techniques and ITTC distance normalization.At the defined distance,the starting point of the tip vortex cavitation is determined for different advance ratios and cavitation numbers using potential flow solver.Also,it is examined that whether the hybrid method and potential flow solver give the same noise results at the inception point of tip vortex cavitation.Results show that TVI method based on potential flow theory is reliable and can practically be used to replace the hybrid method(RANS with FWH approach)when tip vortex cavitation starts.Savas SEZEN Sakir BAL 2020China Ocean Engineering2020,34,2:3
15Effect of early propranolol administration on portal hypertensive gastropathy in cirrhotic rats显示文摘AIM:To investigate any protective effect of early propranolol administration in the development of portal hypertensive gastropathy in cirrhotic rats. METHODS:For the development of liver cirrhosis and portal hypertensive gastropathy,60 rats underwent ligation of the left adrenal vein and complete devascularization of the left renal vein,followed by phenobarbital and carbon tetrachloride(CCl4) administration.After two weeks of CCl4 administration, the rats were randomly separated into two groups.In group A,propranolol was continuously administered intragastrically throughout the study,whereas in group B normal saline(placebo)was administered instead. Hemodynamic studies and vascular morphometric analysis of gastric sections were performed after complete induction of cirrhosis. RESULTS:Vascular morphometric studies showed higher numbers of vessels in all mucosal layers in the control group.Statistical analysis revealed a significantly higher total vascular surface in the control group compared to the propranolol group,but with no statistically significant difference between the mean vascular surfaces between the groups.Our study clearly shows that the increased mucosal blood flow is manifested by a marked increase of vessel count. CONCLUSION:Early propranolol's administration in portal hypertensive cirrhotic rats seems to prevent intense gastric vascular congestion that characterizes portal hypertensive gastropathy.Savas Rafailidis Charalampos Demertzidis Konstantinos Ballas Michail Alatsakis Nikolaos Symeonidis Theodoros Pavlidis Kyriakos Psarras Valentini Tzioufa-Asimakopoulou Athanassios Sakadamis 2009World Journal of Gastroenterology2009,15,34:3
16An axisymmetric model for draft tube flow at partial load显示文摘A new Reynolds-averaged Navier-Stokes(RANS) turbulence model is developed in order to correctly predict the mean flow field in a draft tube operating under partial load using 2-D axisymmetric simulations. It is shown that although 2-D axisymmetric simulations cannot model the 3-D unsteady features of the vortex rope, they can give the average location of the vortex rope in the draft tube. Nevertheless, RANS simulations underpredict the turbulent kinetic energy(TKE) production and diffusion near the center of the draft tube where the vortex rope forms, resulting in incorrect calculation of TKE profiles and, hence, poor prediction of the axial velocity. Based on this observation, a new k-ε turbulence RANS model taking into account the extra production and diffusion of TKE due to coherent structures associated with the vortex rope formation is developed. The new model can successfully predict the mean flow velocity with significant improvements in comparison with the realizable k-ε model. This is attributed to better prediction of TKE production and diffusion by the new model in the draft tube under partial load. Specifically, the new model calculates 31% more production and 46% more diffusion right at the shear layer when compared to the k- ε model.Hosein FOROUTAN Savas YAVUZKURT 2016Journal of Hydrodynamics2016,28,2:3
17Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid显示文摘Addiction to synthetic cannabinoids(SCs) is a growing social and health problem worldwide. Chronic use of SCs may cause adverse effects in the gastrointestinal system. We describe a very rare case of acute gastric dilatation(AGD) and hepatic portal venous gas(HPVG),with findings of acute abdomen resulting from chronic use of a SC, Bonzai. AGD and HPVG were detected by computerized tomography examination. Patchy mucosal ischemia was seen in endoscopic examination. Despite the findings of an acute abdomen, a non-surgical approach with nasogastric decompression, antibiotic therapy, and close radiologic and endoscopic followup was preferred in the presented case. Clinical and radiologic findings decreased dramatically on the first day, and endoscopic findings gradually disappeared over 7 d. In conclusion, this case shows that chronic use of a SC may cause AGD and accompanying HPVG,which can be managed non-surgically despite the findings of acute abdomen.Mert Mahsuni Sevinc Erdem Kinaci Savas Bayrak Aytul Hande Yardimci Ekrem Cakar Hasan Bektas 2015World Journal of Gastroenterology2015,21,37:3
18热处理对Zn−40Al−2Cu−2Si合金力学性能和磨损性能的影响显示文摘为了研究热处理对Zn−40Al−2Cu−2Si合金力学性能和磨损性能的影响,采用不同工艺对其进行热处理,包括均匀化后空冷(H1)、均匀化后炉冷(H2)、稳定化(T5)和淬火−时效(T6和T7)。通过金相、力学实验和磨损实验,研究不同热处理工艺对该合金力学性能和摩擦学性能的影响,并于SAE 65青铜进行对比。磨损实验使用环块式实验装置。结果表明,采用H1和T6热处理可提高合金的硬度、抗拉强度和抗压强度,除T6热处理外的其他热处理均可提高合金的断裂伸长率。经H1、T5和T6热处理后,合金的摩擦因数和磨损量减小,其中T6热处理后合金的摩擦因数和磨损量最低。因此,T6热处理为该合金应用于14 MPa压力下润滑摩擦的最佳工艺。与青铜相比,铸态和热处理态的Zn−40Al−2Cu−2Si合金磨损量较低、耐磨性较高。Temel SAVAŞKAN Zeki AZAKLI Ali Paşa HEKÌMOĞLU 2021Transactions of Nonferrous Metals Society of China2021,31,9:3
19Inducible nitric oxide synthase and histopathological correlation in chronic viral hepatitis显示文摘Esin Atik Yusuf Onlen Lutfu Savas Figen Doran 2007International Journal of Infectious Diseases2007,,1:2
20Post-operative computed tomography scan – reliable tool for quality assessment of complete mesocolic excision显示文摘BACKGROUND Quality control in colon cancer surgery is an ongoing debate ever since standardization proved to be highly efficient in improving survival in rectal cancer. Complete mesocolic excision(CME) is widely acclaimed as the new goldstandard in colon cancer resections, thus it is imperative to establish quality criteria of CME in order to make it easily understood and verified by surgeons worldwide. One simple and reproducible tool could be the measurement of arterial stumps postoperatively and a straightforward way to test its reliability is to test it in a comparative study between CME and non-CME surgery.AIM To validate arterial stump measurement as a surgical quality tool by comparing CME with conventional radical colectomies.METHODS This was a retrospective study, carried out on a prospective database. We collected data from two groups of patients, divided according to standard CME with D2 central vascular ligation(group A) and non-standardized surgery(group B). The two groups were compared with regard to the arterial stump length after right-and left-sided colectomies for colon cancer. The actual stump lengths of the ileocolic artery(ICA) and inferior mesenteric artery(IMA) were compared with their theoretical best D2 position of predicted ligation levels(D2 PLLs) for calculating the potential for improvement. Measurements on follow-up computed tomography scans were carried out by three observers. Pathological data were recorded(specimen length, lymph node yield) and correlated with stump length.RESULTS We analysed 58 colectomies. The stump lengths(mean ± SD) in group A were16.97 ± 4.77 mm for ICA and 31.70 ± 15.71 mm for IMA, whereas group B had 49.93 ± 20.29 mm for ICA and 67.24 ± 28.71 mm for IMA. Shorter lengths were obtained in group A, by a mean difference of 35.66 mm(χ~2 = 27.38, P < 0.001),which was significant for all types of colectomies. Except for a 5.85 ± 4.71 mm difference for right colectomies, all the ligations from group A significantly reached their potential height(0.26 ± 12.18 mm from D2 PLL; χ~2 = 0.005, P = 0.944).Apart from three left colectomies, group B failed to reach D2 PLL, by a mean difference of 32.14 ± 26.15 mm(χ~2 = 21.77, P < 0.001). The calculated improvement potentials were significantly shorter in group A than in group B, by a mean of 31.88 mm(χ~2= 22.13, P < 0.001). The large spread of results in group B showed that there is significant variability(P = 0.004) when compared to standard surgery. Significant correlations were found between stump length, specimen length and number of lymph nodes(P = 0.018 and P = 0.008 respectively). No statistical difference was found between observers' measurements(P = 0.866).CONCLUSION Arterial stump monitoring is a significant step in defining surgical quality, as longer stumps contain residual mesocolic tissue and correlate with major prognostic factors.Cristian Livadaru Stefan Morarasu Tudor Cristian Frunza Florina A Ghitun Elena Florina Paiu-Spiridon Florina Sava Cristina Terinte Dan Ferariu Sorinel Lunca Gabriel Mihail Dimofte 2019World Journal of Gastrointestinal Oncology2019,11,3:2
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