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| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | Self-management of coronary heart disease in older patients after elective percutaneous transluminal coronary angioplasty显示文摘 | Susan Dawkes Graeme D Smith Lawrie Elliott Robert Raeside Jayne H Donaldson | 2016 | Journal of Geriatric Cardiology2016，13，5： | 10 |
| 3 | 膳食中钠(盐)与血压的关系及其他膳食因素可能的调节作用显示文摘现有资料表明,膳食钠(盐)与血压直接相关。以往大多数研究结果来自缺乏膳食数据的研究;因此,这种钠-血压关系是否受其他膳食因素调节尚不清楚。国际宏量/微量营养素和血压研究(international study on macro/micronutrients and blood pressure,INTERMAP)结果显示,在控制多种非膳食因素情况下,年龄40~59岁的男性和女性4680人(中国、日本、英国和美国的17个人口样本)的血压与24h尿钠排泄和尿钠/钾直接相关。 | 刘莉 叶鹏 Stamler J Chan Q Daviglus ML Dyer AR Van Horn L Garside DB Miura K Wu Y Ueshima H Zhao L Elliott P INTERMAP Research Group | 2018 | 中华高血压杂志2018，26，4： | 8 |
| 4 | 改进医疗服务质量、确保病人安全的教学方法显示文摘提高医疗服务质量、确保病人安全是当前医学教育及培训面临的巨大挑战。今天的医生及医务工作者应具备良好的沟通能力,掌握如何在临床实践中鉴别、预防和处理不良事件及接近过失事件(nearmisses),如何使用当前获得的证据及相关信息,如何安全有效地在团队中工作,如何在实践中教授和学习病人安全知识,如何根据认可的伦理原则服务公众。 | Merrilyn M Walton Bruce H Barraclough Samantha A Van Staalduinen Susan L Elliott 段玉蓉(译) 张鸣明(审校) | 2009 | 中国循证医学杂志2009，9，9： | 7 |
| 5 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998，，2： | 4 |
| 6 | ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction显示文摘 | Eugene Braunwald Elliott M Antman John W Beasley Robert M Califf Melvin D Cheitlin Judith S Hochman Robert H Jones Dean Kereiakes Joel Kupersmith Thomas N Levin Carl J Pepine John W Schaeffer Earl E Smith David E Steward Pierre Theroux Raymond J Gibbons J | 2000 | Journal of the American College of Cardiology2000，，3： | 4 |
| 7 | Enhanced dissolution of phosphate rocks in the rhizosphere 显示文摘 | Bolan N S Elliott J Gregg P E H | 1997 | Biology and Fertility of Soils1997，24，： | 1 |
| 8 | Additive Effect of Adenovi-rus-Mediated E2F-1 Gene Transfer and Topoisomerase ]I Inhibi-tors on Apoptosis in Human Osteosarcoma Cells显示文摘 | Yang H L Dong YB Elliott M J | 2001 | Cancer GeneTher2001，8，4： | 1 |
| 9 | Natural algorithms for choosing source locations in active control system显示文摘 | Bake K H Elliott S J | 1995 | Journal of Sound and Vi- bration1995，186，2： | 1 |
| 10 | Roles of various bitumen components in the stability of water-in-diluted-bitumen emulsions显示文摘 | Yan Z L Elliott W Masliyah J H | 1999 | Journal of Colloid and Interface Science1999，220，2： | 1 |
| 11 | Soil carbon pools and fluxes in lung-term corn belt agroeeosystems 显示文摘 | COLLINS H P ELLIOTT E T PAUSTIAN K | 2000 | Soil Biology and Biochemistry2000，32，2： | 1 |
| 12 | Progress in detecting cellsurface protein receptors:the erythropoietin receptor example显示文摘 | Elliott S Sinclair A Collins H | 2014 | Ann Hematol2014，93，2： | 1 |
| 13 | Fractionation of polyethylene显示文摘 | FRSNCIS P S COOKE R C Jr ELLIOTT J H | 1958 | J Polym Sci1958，31，123： | 1 |
| 14 | The effects of sevoflurane and ketamine on intraocular pressure in children during examination under anesthesia 显示文摘 | Blumberg D Congdon N Jampel H Gilbert D Elliott R Rivers R | 2007 | Am J Ophthalmol2007，143，3： | 1 |
| 15 | Altered regulatory properties of human cardiac troponin in mntants that cause hypertrophic cardiomyopathy显示文摘 | Elliott K Watkins H Redwood CS | 2000 | J Biol Chem2000，275，22： | 1 |
| 16 | Soil microbial biomass and selected soil enzyme activities effect of fertilization and cropping practices显示文摘 | Bolton H Jr Elliott L F Papendick R I | 1985 | Soil Bio Biochem1985，17，3： | 1 |
| 17 | Write-ofIs as Accounting Procedures to Manage perceptions 显示文摘 | Elliott J Shaw W H | 1988 | Joumal of Accounting Research1988，，： | 1 |
| 18 | Screening and confirmatory determination of ractopamineresidues in calves treated with growth promoting doses of theβ-agonist显示文摘 | Elliott C Thompson C Crooks S H | 1998 | Analyst1998，123，5： | 1 |
| 19 | Snoring and sleep apnea:a population study in Australian men显示文摘 | Bearpark H Elliott L Crunstein ll | 1995 | Am J Respir Crit Care Med1995，151，20： | 1 |
| 20 | Energy and material flow through the urban ecosystem显示文摘 | Decker E H Elliott S Smith F A | 2000 | Annual Review of Environment and Resources2000，25，： | 1 |
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