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| 1 | 膳食中钠(盐)与血压的关系及其他膳食因素可能的调节作用显示文摘现有资料表明,膳食钠(盐)与血压直接相关。以往大多数研究结果来自缺乏膳食数据的研究;因此,这种钠-血压关系是否受其他膳食因素调节尚不清楚。国际宏量/微量营养素和血压研究(international study on macro/micronutrients and blood pressure,INTERMAP)结果显示,在控制多种非膳食因素情况下,年龄40~59岁的男性和女性4680人(中国、日本、英国和美国的17个人口样本)的血压与24h尿钠排泄和尿钠/钾直接相关。 | 刘莉 叶鹏 Stamler J Chan Q Daviglus ML Dyer AR Van Horn L Garside DB Miura K Wu Y Ueshima H Zhao L Elliott P INTERMAP Research Group | 2018 | 中华高血压杂志2018，26，4： | 8 |
| 2 | Moving Force Identification - Time Domain Method显示文摘 | Law S S Chan T H T Zeng Q H | 1997 | Journal of Sound and Vibration1997，201，1： | 4 |
| 3 | Similar efficacy and safety of tenofovir in Asians and non-Asians with chronic hepatitis B显示文摘AIM:To compare the efficacy and safety of tenofovir disoproxil fumarate(TDF)in Asian and non-Asian chronic hepatitis B(CHB)patients.METHODS:The efficacy and safety of the initial 48wk of treatment with TDF was compared in a posthoc analysis of combined data from 217 Asians and299 non-Asians included in Studies 102 and 103and a post-approval,open-label trial(Study 123).Patient groups were compared according to baseline hepatitis B e antigen(HBe Ag)status and viral load.The main outcome measures included the proportion of patients who achieved a hepatitis B virus(HBV)DNA level<400 copies/m L at Week 48 of treatment.Secondary measures included:HBV DNA and alanine aminotransaminase(ALT)levels over time;proportion of patients with normal ALT levels;proportion of patients with HBe Ag loss/seroconversion and proportion of patients with hepatitis B surface antigen loss/seroconversion;changes in liver histology.Safety and tolerability were evaluated by the occurrence of adverse events(AEs),serious AEs,laboratory abnormalities,discontinuation of the study drug due to AEs,or death.The primary efficacy and safety analysis set included all patients who were randomly assigned to treatment and received at least one dose of study drug.RESULTS:At week 48,similar proportions of Asians and non-Asians reached HBV DNA<400 copies/m L(96%of Asian and 97%of non-Asian patients with HBe Ag-negative CHB and 83%of Asian and 79%of non-Asian patients with HBe Ag-positive CHB had HBV DNA)and normal ALT(78%of Asian and 81%of nonAsian patients with HBe Ag-negative CHB and 71%of Asian and 74%of non-Asian patients with HBe Agpositive CHB had normal ALT).On-treatment HBV DNA decline rates were similar between Asians and nonAsians regardless of baseline HBe Ag status and viralload.HBV DNA decline during the first four weeks was2.9 log10 copies/m L in HBe Ag-negative Asians and nonAsians,and in HBe Ag-positive non-Asians,and 3.1log10 copies/m L in HBe Ag-positive Asians.HBe Ag loss and seroconversion was achieved in 14%of Asians vs 26%and 24%,respectively,in non-Asians.Liver histology improved in 77.2%of Asians and 71.5%of non-Asians.No resistance to TDF developed.No renal safety signals were observed.CONCLUSION:TDF demonstrated similar viral suppression,normalization of ALT,improvements in liver fibrosis,and no detectable resistance in Asian and non-Asian patients regardless of baseline HBe Ag status. | Calvin Q Pan Sing Chan Huy Trinh Alan Yao Ho Bae Lillian Lou | 2015 | World Journal of Gastroenterology2015，21，18： | 4 |
| 4 | Moving Force Identification - A Frequency and Time Domains Approach显示文摘 | LawSS Chan T H T Zeng Q H | 1999 | Journal of Dynamic Systems Measurement and Control ASME1999，121，3： | 2 |
| 5 | Vehicle axle loads identification using finite element method 显示文摘 | Law S S Bu J Q Zhu X Q Chan S L | 2004 | Journal of Engineering Structures2004，26，： | 1 |
| 6 | Performance improvement of pasted nickel electrodes with an addition of ball-milled nickel hydroxide powder显示文摘 | SONG Q CHILI C CHAN S | 2006 | Eleetroehim Aeta2006，51，： | 1 |
| 7 | Formulation development and bioavailability evaluation of a self nanoemulsified drug delivery system of oleanolie acid 显示文摘 | Xi J Chang Q Chan C K | 2009 | AAPS Pharm Sci Tech2009，10，1： | 1 |
| 8 | Cucurb-itacin B induces apoptosis and S phase cell cycle arrest in BEL-7402human hepatocellular carcinoma cells and is effective via oral admin-istration显示文摘 | Chan KT Meng FY Li Q Ho CY Lam TS To Y | 2010 | Cancer Lett2010，294，1： | 1 |
| 9 | The roles of amyloid precur- sor protein (APP) in neurogenesis : Implications to pathogenesis and therapy of Alzheimer disease显示文摘 | ZHOU Z D CHAN C H MA Q H | 2011 | Cell Adhesion & Migration2011，5，4： | 1 |
| 10 | miR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling 显示文摘 | WONG Q W CHING A K CHAN A W | 2010 | Clin Cancer Res2010，16，3： | 1 |
| 11 | A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates显示文摘 | Chan JC Piper DE Cao Q | 2009 | Proc Natl Acad Sci USA2009，106，24： | 1 |
| 12 | Three dimensional simulation for an open channel flow with a constriction 显示文摘 | SHANKAR N J CHAN E S ZHANG Q Y | 2001 | Journal of Hydraulic Reserach2001，39，2： | 1 |
| 13 | Regularization in moving force identification显示文摘 | Law S S Chan T H T Zhu X Q | 2001 | Journal of Engineering Mechanics ASCE2001，127，2： | 1 |
| 14 | Success factors of energy performance contracting (EPC)for sustainable building energy efficiency retrofit (BEER)of hotel buildings in China显示文摘 | XU P CHAN E QIAN Q | 2011 | Energy Policy2011，39，11： | 1 |
| 15 | Biventricular pacing in patients with bradyeardia and normal ejection fraction显示文摘 | Yu CM Chan JY Zhang Q | 2009 | N Engl J Med2009，361，22： | 1 |
| 16 | Nitric oxide induces cyclooxyenase expression and inhibits cell growth in colon cancer cell lines 显示文摘 | Lin Q Chan ST Mahendran LIR | 2003 | Carcinogenesis2003，24，4： | 1 |
| 17 | Optimal designs for an additive quadratic mixture-amount model显示文摘 | Zhang C Q Chan L Y Guan Y N | 2005 | Statistical Sinica2005，15，1： | 1 |
| 18 | Quantitative assessment of diffusion-weighted MR imaging in patients with primary rectal cancer: correlation with FDG-PET/CT显示文摘 | Gu J Khong PL Wang S Chan Q Law W Zhang J | 2011 | Mol Imaging Biol2011，13，： | 1 |
| 19 | Coupling of hydrolog- ic and hydraulic models for the Illinois River Basin显示文摘 | LIAN Y Q CHAN I-C SINGH J | 2007 | Journal of Hydrology2007，344，： | 1 |
| 20 | Improved analytical model for predicting the magnetic field distribution in brushless permanent magnet machines显示文摘 | ZHU Z Q HOWE D CHAN C C | 2002 | IEEE Transactions on Magnetics2002，38，1： | 1 |
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