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| 1 | Processes of coastal ecosystem carbon sequestration and approaches for increasing carbon sink显示文摘The oceans are the largest carbon pools on Earth, and play the role of a 'buffer' in climate change. Blue carbon, the carbon(mainly organic carbon) captured by marine ecosystems, is one of the important mechanisms of marine carbon storage.Blue carbon was initially recognized only in the form of visible coastal plant carbon sequestration. In fact, microorganisms(phytoplankton, bacteria, archaea, viruses, and protozoa), which did not receive much attention in the past, account for more than 90% of the total marine biomass and are the main contributors to blue carbon. Chinese coastal seas, equivalent to 1/3 of China's total land area, have a huge carbon sink potential needing urgently research and development. In this paper, we focus on the processes and mechanisms of coastal ocean's carbon sequestration and the approaches for increasing that sequestration. We discuss the structures of coastal ecosystems, the processes of carbon cycle, and the mechanisms of carbon sequestration. Using the evolution of coastal ocean's carbon sinks in sedimentary records over geologic times, we also discuss the possible effects of natural processes and anthropogenic activities on marine carbon sinks. Finally, we discuss the prospect of using carbon sequestration engineering for increasing coastal ocean's carbon storage capacity. | ZHANG Yao ZHAO MeiXun CUI Qiu FAN Wei QI JiaGuo CHEN Ying ZHANG YongYu GAO KunShan FAN JingFeng WANG GuangYi YAN ChongLing LU HaoLiang LUO YaWei ZHANG ZiLian ZHENG Qiang XIAO Wei JIAO NianZhi | 2017 | Science China Earth Sciences2017，60，5： | 6 |
| 2 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 3 | Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda显示文摘The fall armyworm(FAW),Spodoptera frugiperda,is a destructive pest native to America and has recently become an invasive insect pest in China.Because of its rapid spread and great risks in China,understanding of FAW genetic background and pesticide resistance is urgent and essential to develop effective management strategies.Here,we assembled a chromosome-level genome of a male FAW(SFynMstLFR)and compared re-sequencing results of the populations from America,Africa,and China.Strain identification of 163 individuals collected from America,Africa and China showed that both C and R strains were found in the American pop-ulations,while only C strain was found in the Chinese and African populations.Moreover,population geno-mics analysis showed that populations from Africa and China have close relationship with significantly genetic differentiation from American populations.Taken toge-ther,FAWs invaded into China were most likely origi-nated from Africa.Comparative genomics analysis displayed that the cytochrome p450 gene family is extremely expanded to 425 members in FAW,of which 283 genes are specific to FAW.Treatments of Chinese populations with twenty-three pesticides showed the variant patterns of transcriptome profiles,and several detoxification genes such as AOX,UGT and GST spe-cially responded to the pesticides.These findings will be useful in developing effective strategies for manage-ment of FAW in China and other invaded areas. | Furong Gui Tianming Lan Yue Zhao Wei Guo Yang Dong Dongming Fang Huan Liu Haimeng Li Hongli Wang Ruoshi Hao Xiaofang Cheng Yahong Li Pengcheng Yang Sunil Kumar Sahu Yaping Chen Le Cheng Shuqi He Ping Liu Guangyi Fan Haorong Lu Guohai Hu Wei Dong Bin Chen Yuan Jiang Yongwei Zhang Hanhong Xu Fei Lin Bernard Slippers Alisa Postma Matthew Jackson Birhan Addisie Abate Kassahun Tesfaye Aschalew Lemma Demie Meseret Destaw Bayeleygne Dawit Tesfaye Degefu Feng Chen Paul K.Kuria Zachary M.Kinyua Tong-Xian Liu Huanming Yang Fangneng Huang Xin Liu Jun Sheng Le Kang | 2022 | Protein & Cell2022，13，7： | 2 |
| 4 | Thermodynamic Stability of LiFeO_2 in Molten Carbonate Fuel Cell显示文摘LiFeO2, as one of candidate cathode materials or additive for molten carbonate fuel cell, has been found to be thermodynamically unstable in CO2 atmosphere at 650℃ (the condition of molten carbonate fuel cell) both by computation and experimental confirmation. | Licheng YAN, Wencong LU, Yimin DING, Jianhui MNG and Nianyi CHEN (Department of Chemistry, Shanghai University, Shanghai 201800, China) Guangyi CAO and Jianxin ZHU (Instate of Fuel Cell Technology, Jiaotong University, Shanghai 200030, China) | 2000 | Journal of Materials Science & Technology2000，16，1： | 2 |
| 5 | Investigation on the layout strategy of gg NMOS ESD protection devices for uniform conduction behavior and optimal width scaling显示文摘Gate-grounded NMOS(gg NMOS) transistors have widely served as electro-static discharge(ESD)protection devices for integrated circuits. The layout strategy of gg NMOS greatly influences its ESD protection characteristics. Layout strategies forvariation of the number of substrate-pickup stripes are investigated in this paper. Direct current and transmission-line pulsing test results are presented to verify that adjustable holding voltages are accessed by variation of the number of substrate-pickup stripes. The design with two evenly distributed substrate-pickup stripes among different fingers is found to exhibit the highest second break current and optimal width-scaling characteristics. | LU GuangYi WANG Yuan ZHANG LiZhong CAO Jian JIA Song ZHANG Xing | 2015 | Science China(Information Sciences)2015，58，4： | 2 |
| 6 | Effect of 3D 'π-π stacking on photovoltaic and electroluminescent properties in triphenylamine-containing poly (p-phenyle- nevinylene) derivatives 显示文摘 | Shen Ping Sang Guangyi Lu Junjian | 2008 | Macromolecules2008，41，5： | 1 |
| 7 | The System Performance for TD-LTE with Precoded MIMO显示文摘This paper introduces the rank adaptive precoded MIMO in TD-LTE downlink system. | Zhang Yong Jiang Dajie Shen Xiaodong Han Lu Liu Guangyi Cui Cunfeng Huang Yuhong | 2008 | China Communications2008，5，3： | 1 |
| 8 | Medical Additive Manufacturing: From a Frontier Technology to the Research and Development of Products显示文摘1.Research and development(R&D)and the challenges of raw materials for medical additive manufacturing Raw materials for medical additive manufacturing have a wide range of commonalities that are also seen in many other fields,making them an important basis in the field of three-dimensional(3D)printing.Problems and challenges related to material types,powder properties,formability,viscoelasticity,and so forth also share common features.For example,many metal materials are used in the field of aviation,while metals,polymers,and inorganic materials are used in the field of biomedicine.The most widely used materials in biomedicine are biocompatible.Various homogeneous and non-homogeneous composites are also available for 3D printing,and impose an additional challenge in additive manufacturing;the use of heterogeneous composites in 3D printing is particularly challenging. | Guixing Qiu Wenjiang Ding Wei Tian Ling Qin Yu Zhao Lianmeng Zhang Jian Lu Daijie Chen Guangyi Yuan Chengtie Wu Bingheng Lu Ruxu Du Jimin Chen Mo Elbestawi Zhongwei Gu Dichen Li Wei Sun Yuanjin Zhao Jie He Dadi Jin Bin Liu Kai Zhang Jianmo Li Kam WLeong Dewei Zhao Dingjun Hao Yingfang Ao Xuliang Deng Huilin Yang ShaoKeh Hsu Yingqi Chen Long Li Jianping Fan Guohui Nie Yun Chen Hui Zeng Wei Chen Yuxiao Lai | 2020 | Engineering2020，6，11： | 1 |
| 9 | Genome sequence of cultivated upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution显示文摘 | Li Fuguang Fan Guangyi Lu Cairui | 2015 | Nature Biotechnology2015，33，5： | 1 |
| 10 | Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution显示文摘 | Li Fuguang Fan Guangyi Lu Cairui | 2015 | Nature Biotechnology2015，33，5： | 1 |
| 11 | Cultivation and diversity analysis of novel marine thraustochytrids显示文摘Thraustochytrids are a group of unicellular marine heterotrophic protists,and have long been known for their biotechnological potentials in producing squalene,polyunsaturated fatty acids(PUFAs)and other bioactive products.There are less than a hundred known strains from diverse marine habitats.Therefore,the discovery of new strains from natural environments is still one of the major limitations for fully exploring this interesting group of marine protists.At present,numerous attempts have been made to study thraustochytrids,mainly focusing on isolating new strains,analyzing the diversity in specific marine habitats,and increasing the yield of bioactive substances.There is a lack of a systematic study of the culturable diversity,and cultivation strategies.This paper reviews the distribution and diversity of culturable thraustochytrids from a range of marine environments,and describes in detail the most commonly used isolation methods and the control of culture parameters.Furthermore,the perspective approaches of isolation and cultivation for the discovery of new strains are discussed.Finally,the future directions of novel marine thraustochytrid research are proposed.The ultimate goal is to promote the awareness of biotechnological potentials of culturable thraustochytrid strains in industrial and biomedical applications. | Lu Lyu Qiuzhen Wang Guangyi Wang | 2021 | Marine Life Science & Technology2021，3，2： | 1 |
| 12 | Multiple forms of vitamin B_(6) regulate salt tolerance by balancing ROS and abscisic acid levels in maize root显示文摘Salt stress causes osmotic stress,ion toxicity and oxidative stress,inducing the accumulation of abscisic acid(ABA)and excessive reactive oxygen species(ROS)production,which further damage cell structure and inhibit the development of roots in plants.Previous study showed that vitamin B_(6)(VB_(6))plays a role in plant responses to salt stress,however,the regulatory relationship between ROS,VB_(6) and ABA under salt stress remains unclear yet in plants.In our study,we found that salt stress-induced ABA accumulation requires ROS production,in addition,salt stress also promoted VB_(6)(including pyridoxamine(PM),pyridoxal(PL),pyridoxine(PN),and pyridoxal 5′-phosphate(PLP))accumulation,which involved in ROS scavenging and ABA biosynthesis.Furthermore,VB_(6)-deficient maize mutant small kernel2(smk2)heterozygous is more susceptible to salt stress,and which failed to scavenge excessive ROS effectively or induce ABA accumulation in maize root under salt stress,interestingly,which can be restored by exogenous PN and PLP,respec-tively.According to these results,we proposed that PN and PLP play an essential role in balancing ROS and ABA levels under salt stress,respectively,it laid a foundation for VB_(6) to be better applied in crop salt resistance than ABA. | Chongchong Lu Yuan Tian Xuanxuan Hou Xin Hou Zichang Jia Min Li Mingxia Hao Yanke Jiang Qingbin Wang Qiong Pu Ziyi Yin Yang Li Baoyou Liu Xiaojing Kang Guangyi Zhang Xinhua Ding Yinggao Liu | 2022 | Stress Biology2022，2，1： | 1 |
| 13 | Flotation separation of diaspore from kaolinite, pyrophyllite and illite using three cationic collectors显示文摘 | Hong Zhong Guangyi Liu Liuyin Xia Yiping Lu Yuehua Hu Shenggui Zhao Xinyang Yu | 2008 | Minerals Engineering2008，，： | 1 |
| 14 | Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution显示文摘 | Li Fuguang Fan Guangyi Lu Cairui | 2015 | Nature Biotechnology2015，33，5： | 1 |
| 15 | Genome sequence of cultivated upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution 显示文摘 | Li Fuguang Fan Guangyi Lu Cairui | 2015 | Nature Biotechnology2015，33，5： | 1 |
| 16 | Real-world fuel consumption of light-duty passenger vehicles using on-board diagnostic (OBD) systems显示文摘An increasing discrepancy between real-world and type-approval fuel consumption for light-duty passenger vehicles(LDPVs)has been reported by several studies.Normally,real-world fuel consumption is measured primarily by a portable emission measurement system.The on-board diagnostic(OBD)approach,which is flexible and offers high-resolution data collection,is a promising fuel consumption monitoring method.Three LDPVs were tested with a laboratory dynamometer based on a type-approval cycle,the New European Driving Cycle(NEDC).Fuel consumption was measured by the OBD and constant-volume sampling system(CVS,a regulatory method)to verify the accuracy of the OBD values.The results of the OBD method and the regulatory carbon balance method exhibited a strong linear correlation(e.g.,R^2=0.906-0.977).Compared with the carbon balance results,the fuel consumption results using the OBD were 7.1%±4.3%lower on average.Furthermore,the real-world fuel consumption of six LDPVs was tested in Beijing using the OBD.The results showed that the normalized NEDC real-world fliel consumption of the tested vehicles was 13%±17%higher than the type-approval-based fuel consumption.Because the OBD values are lower than the actual fuel consumption,using a carbon balance method may result in a larger discrepancy between real-word and type-approval ftiel consumption.By means of the operating mode binning and micro trip methods,a strong relationship(R^2=0.984)was established between the average speed and relative fuel consumption.For congested roads(average vehicle speed less than 25 km/h),the fuel consumption of LDPVs is highly sensitive to changes in average speed. | Xuan Zheng Sheng Lu Liuhanzi Yang Min Yan Guangyi Xu Xiaomeng Wu Lixin Fu Ye Wu | 2020 | Frontiers of Environmental Science & Engineering2020，14，2： | 1 |
| 17 | Area-efficient transient power-rail electrostatic discharge clamp circuit with mis-triggering immunity in a 65-nm CMOS process显示文摘A novel, area-efficient transient power-rail electrostatic discharge(ESD) clamp circuit is proposed in this work. Current-mirror capacitors are used to reduce the layout area. Logic threshold voltages of inverters are modified to ensure a fully active on-state for the clamp device in ESD conditions. The proposed circuit reduces the layout area by about 56% compared with a circuit without current-mirror capacitors. Transmission line pulse(TLP) test results based on a 65-nm CMOS process demonstrate that the proposed circuit is an efficient on-chip ESD protection scheme for this process. In addition, the proposed circuit achieves a good immunity to mis-triggering with respect to fast power-up transitions. | Yuan WANG Guangyi LU Haibing GUO Jian CAO Song JIA Xing ZHANG | 2016 | Science China(Information Sciences)2016，59，4： | 1 |
| 18 | A novel approach for preferential flotation recovery of molybdenite from a porphyry copper-molybdenum ore 显示文摘 | Guangyi Liu Yiping Lu Hong Zhong | 2012 | Minerals engineering2012，，10： | 1 |
| 19 | Single-cell-resolution transcriptome map revealed novel genes involved in testicular germ cell progression and somatic cells specification in Chinese tongue sole with sex reversal显示文摘Female-to-male sex reversals(pseudomales)are common in lower vertebrates and have been found in natural populations,which is a concern under rapid changes in environmental conditions.Pseudomales can exhibit altered spermatogenesis.However,the regulatory mechanisms underlying pseudomale spermatogenesis remain unclear.Here,we characterized spermatogenesis in Chinese tongue sole(Cynoglossus semilaevis),a species with genetic and environmental sex determination,based on a highresolution single-cell RNA-seq atlas of cells derived from the testes of genotypic males and pseudomales.We identified five germ cell types and six somatic cell types and obtained a single-cell atlas of dynamic changes in gene expression during spermatogenesis in Chinese tongue sole,including alterations in pseudomales.We detected decreased levels of Ca^(2+)signaling pathway-related genes in spermatogonia,insufficient meiotic initiation in spermatocytes,and a malfunction of somatic niche cells in pseudomales.However,a cluster of CaSR genes and MAPK signaling factors were upregulated in undifferentiated spermatogonia of pseudomales.Additionally,we revealed that Z chromosome-specific genes,such as piwil2,dhx37,and ehmt1,were important for spermatogenesis.These results improve our understanding of reproduction after female-to-male sex-reversal and provide new insights into the adaptability of reproductive strategies in lower vertebrates. | Hong-Yan Wang Xiang Liu Jian-Yang Chen Yingyi Huang Yifang Lu Fujian Tan Qun Liu Mingming Yang Shuo Li Xianghui Zhang Yating Qin Wenxiu Ma Yingming Yang Liang Meng Kaiqiang Liu Qian Wang Guangyi Fan Rafael H.Nóbrega Shanshan Liu Francesc Piferrer Changwei Shao | 2023 | Science China(Life Sciences)2023，66，5： | 1 |
| 20 | A compact SCR model using advanced BJT models and standard SPICE elements显示文摘Dear editor,The Silicon controlled rectifiers(SCR)are widely used to protect integrated circuits(ICs)from electrostatic discharge(ESD)and electrical overstress(EOS)damage[1].An accurate SCR model is highly desirable in on-chip ESD protection design.Previous studies modeled SCRs by aggregating conventional bipolar junction transistor(BJT)models and adding extra physical models that conventional BJT models fail to support[2,3].However the auxiliary models are mostly | Jian CAO Jingya XU Yuan WANG Guangyi LU Xing ZHANG | 2016 | Science China(Information Sciences)2016，59，10： | 1 |
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