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| 1 | Viral effector protein manipulates host hormone signaling to attract insect vectors显示文摘 | Dewei Wu Tiancong Qi Wan-Xiang Li Haixia Tian Hua Gao Jiaojiao Wang Jin Ge Ruifeng Yao Chunmei Ren Xian-Bing Wang Yule Liu Le Kang Shou-Wei Ding Daoxin Xie | 2017 | Cell Research2017，27，3： | 20 |
| 2 | Aliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in mice显示文摘 | Li-qing WENG Wen-bin ZHANG Yong YE Pei-pei YIN Jie YUAN Xing-xu WANG Le KANG Sha-sha JIANG Jie-yun YOU Jian WU Hui GONG Jun-bo GE Yun-zeng ZOU | 2014 | Acta Pharmacologica Sinica2014，35，8： | 12 |
| 3 | MicroRNA-dependent development revealed by RNA interference-mediated gene silencing of LmDicerl in the migratory locust显示文摘MicroRNAs (miRNAs ) 是小 noncoding RNA,它参予许多生物过程。在迁移的蝗虫的小 RNA transcriptome 被描绘了, 50 保存了, 185 个潜在的蝗虫特定的 miRNA 家庭候选人用高产量的定序被识别了 miRNA 家庭。然而,它是不清楚的是否 miRNAs 影响许多蝗虫生物进程,例如生长或开发。在昆虫, Dicer1 ribonuclease 把 miRNA 先锋转变成成熟 miRNAs。因此,使用全身的 RNA 干扰(RNAi ) 到沉默在迁移的蝗虫的 Dicer1 的表示,草之小穗 migratoria,我们在蝗虫减少了 miRNA 内容并且破坏了脱毛(nymphnymph,和 nymphadult ) 的二种类型。LmDicer1 的 RNAi 也在 L 导致了高死亡。migratora。我们的学习表明 LmDicer1 为 miRNA 规定和 L 的开发是必要的。migratoria。这些结果进一步支持我们 LmDicer1 能为为控制这个重要昆虫害虫开发新奇策略作为一个优秀目标服务的观点。 | Yan-Li Wang Mei-Ling Yang Feng Jiang Jian-Zhen Zhang Le Kang | 2013 | Insect Science2013，20，1： | 11 |
| 4 | Optimization of Agrobacterium tumefaciens-Mediated Transformation Systems in Tea Plant(Camellia sinensis)显示文摘In this study, an efficient plant regeneration protocol in vitro and transformation by Agrobacterium-mediated method of Camellia sinensis was achieved, which would lay the foundation for genetic improvement of tea plant by genetic engineering technology. The cotyledon callus of C.sinensis were used as the receptors for transformation by Agrobacterium tumefaciens EHA105 containing PS1aG-3. Some factors which affected the result of Agrobacterium-mediated transformation of C. sinensis were studied on the basis of GUS transient expression system. The optimum system of Agrobacterium-mediated transformation was that the cotyledon callus were pre-cultured for 3 d, and then infected by EHA105 for 15 min followed by 3 d co-culture in the dark on the YEB medium containing 150 μmol·L^(-1) acetosyringone(AS). The transient expression rate of GUS gene was 62.6%. After being delayed selective culture for 3 d, infected callus were transferred into the differentiation medium and the root induction medium both of which were supplemented with 100 mg·L^(-1) spectinomycin, and then resistant seedlings of C. sinensis were obtained. The conversion rate was 3.6%. | LV Qianru CHEN Changsong XU Yijuan HU Shunkai WANG Le SUN Kang CHEN Xuan LI Xinghui | 2017 | Horticultural Plant Journal2017，3，3： | 9 |
| 5 | Efficient spectral regulation in Ce:Lu_(3)(Al,Cr)_(5)O_(12) and Ce:Lu_(3)(Al,Cr)_(5)O_(12)/Ce:Y_(3)Al_(5)O_(12) transparent ceramics with high color rendering index for high-power white LEDs/LDs显示文摘Realizing a high color rendering index(CRI)in Ce:LuAG transparent ceramics(TCs)with desired thermal stability is essential to their applications in white LEDs/LDs as color converters.In this study,based on the scheme of configuring the red component by Cr^(3+) doping,an efficient spectral regulation was realized in Ce,Cr:LuAG TCs.A unilateral shift phenomenon could be observed in both photoluminescence(PL)and photoluminescence excitation(PLE)spectra of TCs.By constructing TC-based white LED/LD devices in a remote excitation mode,luminescence properties of Ce,Cr:LuAG TCs were systematically investigated.The CRI values of Ce:LuAG TC based white LEDs could be increased by a magnitude of 46.2%.Particularly,by combining the as fabricated Ce,Cr:LuAG TCs with a 0.5 at% Ce:YAG TC,surprising CRI values of 88 and 85.5 were obtained in TC based white LEDs and LDs,respectively.Therefore,Ce,Cr:LuAG TC is a highly promising color convertor for high-power white LEDs/LDs applied in general lighting and displaying. | Tianyuan ZHOU Chen HOU Le ZHANG Yuelong MA Jian KANG Tao LI Rui WANG Jin HUANG Junwei LI Haidong REN Zhenxiao FU Farida ASELIM Ming LI Hao CHEN | 2021 | Journal of Advanced Ceramics2021，10，5： | 7 |
| 6 | Month ahead average daily electricity price profile forecasting based on a hybrid nonlinear regression and SVM model:an ERCOT case study显示文摘With the deregulation of the electric power industry, electricity price forecasting plays an increasingly important role in electricity markets, especially for retailors and investment decision making. Month ahead average daily electricity price profile forecasting is proposed for the first time in this paper. A hybrid nonlinear regression and support vector machine(SVM) model is proposed. Offpeak hours, peak hours in peak months and peak hours in off-peak months are distinguished and different methods are designed to improve the forecast accuracy. A nonlinear regression model with deviation compensation is proposed to forecast the prices of off-peak hours and peak hours in off-peak months. SVM is adopted to forecast the prices of peak hours in peak months. Case studies based on data from ERCOT validate the effectiveness of the proposed hybrid method. | Ziming MA Haiwang ZHONG Le XIE Qing XIA Chongqing KANG | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，2： | 6 |
| 7 | Different evolutionary lineages of large and small heat shock proteins in eukaryotes显示文摘 | Li-Hua Huang Hong-Sheng Wang Le Kang | 2008 | Cell Research2008，18，10： | 5 |
| 8 | Integrated energy storage system based on triboelectric nanogenerator in electronic devices显示文摘The emergence of electronic devices has brought earth-shaking changes to people's life.However,an extemal power source may become indispensable to the electronie devices due to the limited capacity of batteries.As one of the possible solutions for the extermal power sources,the triboelectric nanogenerator(TENG)provides a novel idea to the increasing mumber of personal electronic devices.TENG is a new type of energy ollector,which has become a hot spot in the field of nanotechnology.It is widely used at the acquisition and conversion of mechan-ical enegy to electrice energy through the principle of electrostatic induction.On this basis,the TENG could be integrated with the energy stonage system into a self-powered system,W hich can supply power to the electronic devices and make them work continuously.In this review,TENG's basic structure as well as its working process and working mode are firstly discussed.The integration method of TENGs with enegy storage systems and the related research status are then introduced in detail.At the end of this paper,we put forward some problems and discuss the prospect in the future. | Xiao Feng Yang Zhang Le Kang Licheng Wang Chongxiong Duan Kai Yin Jinbo Pang Kai Wang | 2021 | Frontiers of Chemical Science and Engineering2021，15，2： | 5 |
| 9 | Influence of Livestock Grazing on Grasshopper (Orthoptera: Acrididae) Diversity in the Inner Mongolian Steppes显示文摘 | KANG LE | 1994 | 生物多样性1994，2，B11： | 4 |
| 10 | Core transcriptional signatures of phase change in the migratory locust显示文摘Phenotypic plasticity plays fundamental roles in successful adaptation of animals in response to environmental variations.Here,to reveal the transcriptome reprogramming in locust phase change,a typical phenotypic plasticity,we conducted a comprehensive analysis of multiple phase-related transcriptomic datasets of the migratory locust.We defined PhaseCore genes according to their contribution to phase differentiation by the adjustment for confounding principal components analysis algorithm(AC-PCA).Compared with other genes,PhaseCore genes predicted phase status with over 87.5%accuracy and displayed more unique gene attributes including the faster evolution rate,higher CpG content and higher specific expression level.Then,we identified 20 transcription factors(TFs)named PhaseCoreTF genes that are associated with the regulation of PhaseCore genes.Finally,we experimentally verified the regulatory roles of three representative TFs(Hr4,Hr46,and grh)in phase change by RNAi.Our findings revealed that core transcriptional signatures are involved in the global regulation of locust phase changes,suggesting a potential common mechanism underlying phenotypic plasticity in insects.The expression and network data are accessible in an online resource called LocustMine(http://gffzz3cb74c7b86e54fech9oxkuxw5o9vv6okw.ffgz.tsg.suse.edu.cn/locustmine). | Pengcheng Yang Li Hou Xianhui Wang Le Kang | 2019 | Protein & Cell2019，10，12： | 4 |
| 11 | Constructing Straight Pores and Improving Mechanical Properties of GangueBased Porous Ceramics显示文摘The large-scale accumulation and pollution of solid mining waste is an urgent issue.Coal gangue is a prominent type of solid waste,and shows promise for use in high value-added products due to its content of many important compounds,including SiO_(2) and Al2O3.This study proposed the preparation of highly porous ceramics from coal gangue,coal slime,and coconut palm fibers.The ceramics were produced at a sintering temperature of 950℃ with a fiber content of 6 wt%,which led to the formation of porous ceramics with a porosity of 66.93%,volume density of 1.0329 g/cm^(3),compressive strength of 1.1025 MPa,and thermal conductivity is 0.3919 K(W/mk).A finite element model of the porous ceramics was established using the Abaqus module in ANSYS software,where the stress distribution and compressive strength were simulated.Further,the relationship between porosity and compressive strength was analyzed.The thermal properties of the porous ceramics were analyzed using the Fluent module,where the simulated changes in porosity under various sintering temperatures were consistent with the experimental data.The preparation of this highly porous ceramic from solid waste coal gangue shows promise for the minimizing the impact of waste gas and wastewater pollution in the future. | Hang Xu Huiling Du Le Kang Qiudi Cheng Danni Feng Siyu Xia | 2021 | Journal of Renewable Materials2021，9，12： | 4 |
| 12 | The effect of monosialylganglioside mix modifying the PEGylated liposomal epirubicin on the accelerated blood clearance phenomenon显示文摘PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. However, PEG-modified liposomes can induce accelerated blood clearance(ABC) upon repeated administration, and the extent of ABC phenomenon on the cytotoxic drugs-containing PEGylated liposomes is related to the dose of the cytotoxic drugs.In this study, EPI served as a model cytotoxic drug, a hydrophilic surfactant molecule,monosialylganglioside(GM1) was chosen and modified on the liposomes together with PEG.It was shown that upon mixed modification, when GM1 contents reached 10% or 15% mol,the ABC phenomenon of the PEGylated liposomal EPI significantly reduced. We also found that GM1 played an important role in abrogating the ABC phenomenon in both the induction phase and the effectuation phase. The results suggested that GM1 incorporation unfortunately did not avoid occurrence of ABC phenomenon completely, but GM1 modification on PEGylated liposomes may provide a significant improvement in clinical practice of PEGylated liposomes. Further study must be necessary. | Ting Zhang Songlei Zhou Le Kang Xiang Luo Yang Liu Yanzhi Song Xinrong Liu Yihui Deng | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，2： | 3 |
| 13 | Integration strategies of hydrogen network in a refinery based on operational optimization of hydrotreating units显示文摘Inferior crude oil and fuel oil upgrading lead to escalating increase of hydrogen consumption in refineries.It is imperative to reduce the hydrogen consumption for energy-saving operations of refineries.An integration strategy of hydrogen network and an operational optimization model of hydrotreating(HDT)units are proposed based on the characteristics of reaction kinetics of HDT units.By solving the proposed model,the operating conditions of HDT units are optimized,and the parameters of hydrogen sinks are determined by coupling hydrodesulfurization(HDS),hydrodenitrification(HDN)and aromatic hydrogenation(HDA)kinetics.An example case of a refinery with annual processing capacity of eight million tons is adopted to demonstrate the feasibility of the proposed optimization strategies and the model.Results show that HDS,HDN and HDA reactions are the major source of hydrogen consumption in the refinery.The total hydrogen consumption can be reduced by 18.9%by applying conventional hydrogen network optimization model.When the hydrogen network is optimized after the operational optimization of HDT units is performed,the hydrogen consumption is reduced by28.2%.When the benefit of the fuel gas recovery is further considered,the total annual cost of hydrogen network can be reduced by 3.21×10~7CNY·a^(-1),decreased by 11.9%.Therefore,the operational optimization of the HDT units in refineries should be imposed to determine the parameters of hydrogen sinks base on the characteristics of reaction kinetics of the hydrogenation processes before the optimization of the hydrogen network is performed through the source-sink matching methods. | Le Wu Xiaoqiang Liang Lixia Kang Yongzhong Liu | 2017 | Chinese Journal of Chemical Engineering2017，25，8： | 3 |
| 14 | Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda显示文摘The fall armyworm(FAW),Spodoptera frugiperda,is a destructive pest native to America and has recently become an invasive insect pest in China.Because of its rapid spread and great risks in China,understanding of FAW genetic background and pesticide resistance is urgent and essential to develop effective management strategies.Here,we assembled a chromosome-level genome of a male FAW(SFynMstLFR)and compared re-sequencing results of the populations from America,Africa,and China.Strain identification of 163 individuals collected from America,Africa and China showed that both C and R strains were found in the American pop-ulations,while only C strain was found in the Chinese and African populations.Moreover,population geno-mics analysis showed that populations from Africa and China have close relationship with significantly genetic differentiation from American populations.Taken toge-ther,FAWs invaded into China were most likely origi-nated from Africa.Comparative genomics analysis displayed that the cytochrome p450 gene family is extremely expanded to 425 members in FAW,of which 283 genes are specific to FAW.Treatments of Chinese populations with twenty-three pesticides showed the variant patterns of transcriptome profiles,and several detoxification genes such as AOX,UGT and GST spe-cially responded to the pesticides.These findings will be useful in developing effective strategies for manage-ment of FAW in China and other invaded areas. | Furong Gui Tianming Lan Yue Zhao Wei Guo Yang Dong Dongming Fang Huan Liu Haimeng Li Hongli Wang Ruoshi Hao Xiaofang Cheng Yahong Li Pengcheng Yang Sunil Kumar Sahu Yaping Chen Le Cheng Shuqi He Ping Liu Guangyi Fan Haorong Lu Guohai Hu Wei Dong Bin Chen Yuan Jiang Yongwei Zhang Hanhong Xu Fei Lin Bernard Slippers Alisa Postma Matthew Jackson Birhan Addisie Abate Kassahun Tesfaye Aschalew Lemma Demie Meseret Destaw Bayeleygne Dawit Tesfaye Degefu Feng Chen Paul K.Kuria Zachary M.Kinyua Tong-Xian Liu Huanming Yang Fangneng Huang Xin Liu Jun Sheng Le Kang | 2022 | Protein & Cell2022，13，7： | 2 |
| 15 | Fluorine doping for improved thermoelectric properties of spark plasma sintered bismuth telluride显示文摘Bismuth-telluride(Bi_(2)Te_(3))is considered to have the best thermoelectric properties at room temperature(ca.300 K).Thus,synthesis and improvement of Bi_(2)Te_(3)and its derivatives quickly and cost-effectively at favorite temperatures are of interests.Recently,doping fluorine(F)into electronic materials(e.g.,FTO)has gained attention;however,it is not applied to Bi_(2)Te_(3)till now.Here,our synthesis of F-doped Bi_(2)Te_(3)for thermoelectric application is introduced using spark plasma sintering(SPS)for Bi_(2)Te_(3)preparation and reactive ion etching(RIE,with SF_6 gas)for F-doping.The exposure time of SF_6 plasma is adjusted to evaluate F-doping effect on the thermoelectric properties of the samples.During characterizations,the increased electrical conductivity and the improved Seebeck coefficient of F-doped Bi_(2)Te_(3)are observed.Through spectroscopic studies and DFT calculations,the main mechanism behind that improvement is unveiled.It also emphasizes the essential role of the F-doping(optimum treatment time of 40 s)in increasing the carrier concentrations as well as electrical conductivity.With increasing measurement temperature(300-510 K),F-doping raises the figure of merit of electron rich Bi_(2)Te_(3)from 1.0 to 1.11(peaked at 390 K). | Jinseo Kim Le Thai Duy Hyunwoo Kang Byungmin Ahn Hyungtak Seo | 2021 | Journal of Materials Science & Technology2021，，31： | 2 |
| 16 | Comparison of the olfactory sensitivity of two sympatric steppe grasshopper species(Orthoptera:Acrididae)to plant volatile compounds显示文摘Electroantennogram (EAG) responses of male and female Oedipodinae grasshop-pers, Oedaleus decorus asiaticus B.-Bienko and Angaracris barabensis Pall to 37 plant volatile compounds were recorded. The two species have sympatric distribution and synchronous sea-sonal activity in Inner Mongolia Grasslands. They have different host plant preference with Oedaleus decorus asiaticus graminivorous and A. barabensis forbivorous. The EAG response profiles to 37 compounds of the two species and their both sexes were similar. Most of the green leaf volatiles elicited higher EAG responses in both species and sexes than terpenic compounds and some aromatic compounds. Strong EAG responses were elicited by 6-carbon alcohols (1-hexanol, Z-hexen-2-ol-1, E-2-hexen-1-ol, E-hexen-3-ol-1), aldehyde (E-2-hexen-1-al), ester (Z-hexen-3-yl acetate), and 7-carbon alcohols (1-heptanol) in both species and sexes. Monoterpenes with functional groups of alcohols and aldehydes were more stimulating than other monoterpenes tested. The sesquiterpenes tested elicited relatively low responses. Ben-zaldehyde elicited the highest responses for both species among aromatic components. Oedaleus decorus asiaticus showed higher EAG responses than A. barabensis to the green leaf volatiles, 1-decanol, 1-nonanol, 1-pentanol, hexanal, Z-hexen-3-yl acetate and to the sesquiter-penes (-)-trans-caryophyllene. Males have higher responses than females in Oedaleus decorus asiaticus. No sexual difference was observed in A. barabensis. Dose-dependent responses to six selected chemicals were observed from females. In both species, all the chemicals tested elicit EAG responses at concentration between 10-3 mol/L and 10-2 mol/L, except that the responses of A. barabensis to terpineol had a threshold concentration of 10-2 mol/L benzaldehyde and 1-hexanol had the highest slopes in dose curves, while 1-octen-3-ol showed the smallest slope in responses to the six chemicals tested. Comparative studies on the responses of two antennal sections and the whole antenna to six selected chemicals were carried out using females of both species. A significant EAG response was only recorded from the distal part of the antenna and not from the proximal seven segments. | CHEN Huhai ZHAO Yunxian KANG Le | 2004 | Science China(Life Sciences)2004，47，2： | 2 |
| 17 | Composition and emission dynamics of migratory locust volatiles in response to changes in developmental stages and population density显示文摘化学通讯在蝗虫在密度依赖者阶段变化起一个重要作用。然而,迁移的蝗虫的不稳定的部件和排出物模式,草之小穗 migratoria,大部分是未知的。在这研究,我们从身体和排汇物识别了化学作文和蝗虫 volatiles 的排放动力学并且把他们与发展阶段,性和阶段变化联系了。迁移的蝗虫与荒芜的蝗虫(Schistocerca gregaria ) 分享很多个不稳定的部件,但是二蝗虫种的排放动力学是显著地不同的。在迁移的蝗虫的群居的美女的身体气味由 phenylacetonitrile (平底锅) 组成了, benzaldehyde, guaiacol,酚,脂肪族的酸和 2,3-butanediol,和平底锅是主导不稳定。从美女的烘便的小团的 Volatiles 首先由 guaiacol 和酚组成。主要部件分析(PCA ) 在在群居、独居的蝗虫之间的不稳定的侧面显示出重要差别。平底锅和 4-vinylanisole 集中比在独居的蝗虫在群居的个人是显著地更高的。群居的成熟男性比成熟女性和两性的不成熟的成年人在成人生活期间释放了平底锅和 4-vinylanisole 的显著地更高的数量。而且,平底锅和 4-vinylanisole 完全在 solitarization 过程期间在群居的美女被失去,但是被独居的美女在 gregarization 期间获得。benzaldehyde, guaiacol 和酚的数量仅仅单向性地减少了从对拥挤的处理独居。脂肪族的醛(到 C10 的 C7 ) 以前作为蝗虫 volatiles 被报导,是作为环境沾染物识别的现在。因此,我们的结果在发展阶段,性和阶段变化期间说明迁移的蝗虫的精确气味侧面。然而,平底锅和另外的芳香的混合物的功能和角色需要在阶段转变期间推进调查。 | Jianing Wei Wenbo Shao Xianhui Wang Jin Ge Xiangyong Chen Dan Yu Le Kang | 2017 | Insect Science2017，24，1： | 2 |
| 18 | Effects of mating status on copulation investment by male bushcricket Gampsocleis gratiosa (Tettigoniidae, Orthoptera)显示文摘Male’s copulation investment, including spermatophore and sperm investment were very high in the Chinese bushcricket Gampsocleis gratiosa. The effects of mating status of both males and females on male’s copulation investment were examined in this study. The fresh weight of sper-matophylax increased positively with the weight of males’ body. This indicated that the nutritional in-vestment during copulation depended on male’s quality. Spermatophore investment showed insig-nificant differences in every copulation protocols. This finding supported the paternal investment hy-pothesis, that is, males contributed to their offspring with little attention to their partners. Sperm re-leasing per ejaculation varied significantly among the trials. Males decreased 54.19% sperm in sec-ond mating than in its first mating, demonsrated that males regarded the first mating highly, and were more prudent in subsequent mating. These males’ strategies may contribute to the viability of the offspring. | GAO Yong KANG Le | 2006 | Science China(Life Sciences)2006，49，4： | 2 |
| 19 | Recent advances in the synthesis of nanoscale hierarchically porous metal–organic frameworks显示文摘Nanoscale hierarchically porous metal–organic frameworks(NHP-MOFs)have received unprecedented attention in many fields owing to their integration of the strengths of nanoscale size(<1μm)and hierarchical porous structure(micro-,meso-and/or macro-pores)of MOFs.This review focuses on recent advances in the main synthetic strategies for NHP-MOFs based on different metal ions(e.g.,Cu,Fe,Co,Zn,Al,Zr,and Cr),including the template method,composite technology,post-synthetic modification,in situ growth and the grind method.In addition,the mechanisms of synthesis,regulation techniques and the advantages and disadvantages of various methods are discussed.Finally,the challenges and prospects of the commercialisation of promising NHP-MOFs are also presented.The purpose of this review is to provide a road map for future design and development of NHP-MOFs for practical application. | Chongxiong Duan Kuan Liang Zena Zhang Jingjing Li Ting Chen Daofei Lv Libo Li Le Kang Kai Wang Han Hu Hongxia Xi | 2022 | Nano Materials Science2022，4，4： | 2 |
| 20 | The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication显示文摘Rice stripe virus(RSV)transmitted by the small brown planthopper causes severe rice yield losses in Asian countries.Although viral nuclear entry promotes viral replication in host cells,whether this phenomenon occurs in vector cells remains unknown.Therefore,in this study,we systematically evaluated the presence and roles of RSV in the nuclei of vector insect cells.We observed that the nucleocapsid protein(NP)and viral genomic RNAs were partially transported into vector cell nuclei by utilizing the importin a nuclear transport system.When blocking NP nuclear localization,cytoplasmic RSV accumulation significantly increased.In the vector cell nuclei,NP bound the transcription factor YY1 and affected its positive regulation to FAIM.Subsequently,decreased FAIM expression triggered an antiviral caspase-dependent apoptotic reaction.Our results reveal that viral nuclear entry induces completely different immune effects in vector and host cells,providing new insights into the balance between viral load and the immunity pressure in vector insects. | Wan Zhao Junjie Zhu Hong Lu Jiaming Zhu Fei Jiang Wei Wang Lan Luo Le Kang Feng Cui | 2022 | Protein & Cell2022，13，5： | 2 |
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