3篇
您的检索式：作者名="Francesc Piferrer"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Single-cell-resolution transcriptome map revealed novel genes involved in testicular germ cell progression and somatic cells specification in Chinese tongue sole with sex reversal显示文摘Female-to-male sex reversals(pseudomales)are common in lower vertebrates and have been found in natural populations,which is a concern under rapid changes in environmental conditions.Pseudomales can exhibit altered spermatogenesis.However,the regulatory mechanisms underlying pseudomale spermatogenesis remain unclear.Here,we characterized spermatogenesis in Chinese tongue sole(Cynoglossus semilaevis),a species with genetic and environmental sex determination,based on a highresolution single-cell RNA-seq atlas of cells derived from the testes of genotypic males and pseudomales.We identified five germ cell types and six somatic cell types and obtained a single-cell atlas of dynamic changes in gene expression during spermatogenesis in Chinese tongue sole,including alterations in pseudomales.We detected decreased levels of Ca^(2+)signaling pathway-related genes in spermatogonia,insufficient meiotic initiation in spermatocytes,and a malfunction of somatic niche cells in pseudomales.However,a cluster of CaSR genes and MAPK signaling factors were upregulated in undifferentiated spermatogonia of pseudomales.Additionally,we revealed that Z chromosome-specific genes,such as piwil2,dhx37,and ehmt1,were important for spermatogenesis.These results improve our understanding of reproduction after female-to-male sex-reversal and provide new insights into the adaptability of reproductive strategies in lower vertebrates. | Hong-Yan Wang Xiang Liu Jian-Yang Chen Yingyi Huang Yifang Lu Fujian Tan Qun Liu Mingming Yang Shuo Li Xianghui Zhang Yating Qin Wenxiu Ma Yingming Yang Liang Meng Kaiqiang Liu Qian Wang Guangyi Fan Rafael H.Nóbrega Shanshan Liu Francesc Piferrer Changwei Shao | 2023 | Science China(Life Sciences)2023，66，5： | 1 |
| 2 | Ovarian aromatase and estrogens: A pivotal role for gonadal sex differentiation and sex change in fish显示文摘 | Yann Guiguen Alexis Fostier Francesc Piferrer Ching-Fong Chang | 2009 | General and Comparative Endocrinology2009，，3： | 1 |
| 3 | Aromatase distribution and regulation in fish显示文摘 | Francesc Piferrer Mereedes Blazquez | 2005 | Fish Physiology and Biochemistry2005，31，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员