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| 1 | COX-2 polymorphisms-765G→C and-1195A→G and colorectal cancer risk显示文摘AIM:To determine the possible modulating effect of the COX-2 polymorphisms,-765G→C and-1195A→G, on the risk of colorectal cancer(CRC)in a Dutch population. METHODS:This case-control study includes 326 patients with CRC and 369 age-and gender-matched controls.Genotypes of the COX-2 polymorphisms -765G→C and-1195A→G were determined by polymerase chain reaction-based restriction fragment length polymorphism.COX-2 genotypes and haplotypes were analyzed and odds ratios with 95%confi- dence intervals were estimated by logistic regression. RESULTS:The-765GG genotype was associated with an increased risk of developing CRC(OR,1.45; 95%CI,1.03-2.04).No significant difference was observed in the genotype distribution of the-1195A→ G polymorphism between patients and controls.The GG/AC haplotype was present significantly less often in patients than in controls(OR 0.44;95%CI,0.22-0.85). When the AC,AG and GG haplotypes were investigated separately,the AC haplotype showed a tendency to be less frequent in patients than in controls(OR(AG/AC)0.78; 95%CI,0.57-1.06). CONCLUSION:The-765GG genotype is associatedwith an increased risk of developing CRC and the GG/ AC haplotype seems to protect against CRC.These findings suggest a modulating role for the COX-2 polymorphisms-765G→C and-1195A→G in the development of CRC in a Dutch population. | Juliёt H Hoff Rene HM te Morsche Hennie MJ Roelofs Elise MJ van der Logt Fokko M Nagengast Wilbert HM Peters | 2009 | World Journal of Gastroenterology2009,15,36: | 6 |
| 2 | 磷烯包覆的高性能硅基锂离子电池负极材料(英文)显示文摘硅基锂离子负极材料在脱嵌锂离子的过程中显著的体积效应导致活性材料的粉化、固体电解质介面膜(SEI)的持续生长和电接触的丧失并最终导致电池的失效。本文报道了一种新型的磷烯(单层黑磷)包覆来提升硅基负极材料的电化学性能。微量(1%,质量分数)的磷烯包覆有效抑制了被包覆硅颗粒的体积膨胀和SEI生长等问题,并保持了其电极结构在持续充放电循环中的完整性,从而提升了其库伦效率、容量以及循环稳定性。这是首次利用磷烯包覆法来提升硅基锂离子电池负极材料电化学性能的报道,而且也展现了此工艺在其他具有显著体积效应的电池材料中具有应用前景。 | 彭勃 徐耀林 Fokko M.Mulder | 2017 | 物理化学学报2017,33,11: | 3 |
| 3 | Fate of fructo-oligosaccharides in the human intestine显示文摘 | Martine S A Joseph G A J H Fokko M N | | 0,,02: | 1 |
| 4 | Risk of Developing Adenomas and Carcinomas in the Ileal Pouch in Patients With Familial Adenomatous Polyposis显示文摘 | Pieter Friederich Andrea E. de Jong Lisbeth M. Mathus–Vliegen Eveline Dekker Han H. Krieken Jan Dees Fokko M. Nagengast Hans F.A. Vasen | 2008 | Clinical Gastroenterology and Hepatology2008,,11: | 1 |
| 5 | Mycophenolate mofetil for systemic vasculitis and IgA nephropathy 显示文摘 | Nowack R Birck R Fokko J | 1997 | Lancet1997,349,9054: | 1 |
| 6 | Mycophenolate mofetil for systemic vasculitis and IgA nephropathy显示文摘 | Nowack R Birck R Fokko J | 1997 | Lancet1997,349,: | 1 |
| 7 | A Nationwide Survey Evaluating Adherence to Guidelines for Follow-up After Polypectomy or Treatment for Colorectal Cancer显示文摘 | Sanna A. Mulder Rob J.Th. Ouwendijk Monique E. van Leerdam Fokko M. Nagengast Ernst J. Kuipers | 2008 | Journal of Clinical Gastroenterology2008,,: | 1 |
| 8 | Methyl modified MOF-5: a water stable hydrogen storage material显示文摘 | Yang Jie Grzeeh Anna Mulder Fokko M Dingemans Theo J | 2011 | Chemical Communications2011,47,: | 1 |
| 9 | The electrochemical performance of super P carbon black in reversible Li/Na ion uptake显示文摘Super P carbon black (SPCB) has been widely used as a conducting additive in Li/Na ion batteries to improve the electronic conductivity. However, there has not yet been a comprehensive study on its structure and electrochemical properties for Li/Na ion uptake, though it is important to characterize its contribution in any study of active materials that uses this additive in non-negligible amounts. In this article the structure of SPCB has been characterized and a comprehensive study on the electrochemical Li/Na ion uptake capability and reaction mechanisms are reported. SPCB exhibits a considerable lithiation capacity (up to 310 mAh g^(–1)) from the Li ion intercalation in the graphite structure. Sodiation in SPCB undergoes two stages: Na ion intercalation into the layers between the graphene sheets and the Na plating in the pores between the nano-graphitic domains, and a sodiation capacity up to 145 mAh g^(–1) has been achieved. Moreover, the influence of the type and content of binders on the lithiation and sodiation properties has been investigated. The cycling stability is much enhanced with sodium carboxymethyl cellulose (NaCMC) binder in the electrode and fluoroethylene carbonate (FEC) in the electrolyte; and a higher content of binder improves the Coulombic efficiency during dis-/charge. | Bo Peng Yaolin Xu Xiaoqun Wang Xinghua Shi Fokko M. Mulder | 2017 | Science China(Physics,Mechanics & Astronomy)2017,60,6: | 1 |
| 10 | Increased circulating endothelial progenitor cells in septic patients: Correlation with survival显示文摘 | Neysan Rafat Christine Hanusch Paul T. Brinkkoetter Jutta Schulte Joachim Brade Jan G. Zijlstra Fokko J. van der Woude Klaus van Ackern Benito A. Yard Grietje Ch. Beck | 2007 | Critical Care Medicine2007,,7: | 1 |
| 11 | Decrease in Mortality in Lynch Syndrome Families Because of Surveillance显示文摘 | Andrea E. de Jong Yvonne M.C. Hendriks Jan H. Kleibeuker Sybrand Y. de Boer Annemieke Cats Gerrit Griffioen Fokko M. Nagengast Frits G. Nelis Matti A. Rookus Hans F.A. Vasen | 2006 | Gastroenterology2006,,3: | 1 |
| 12 | CASE REPORT: Recurrent Esophageal Fibrovascular Polyps: Case History and Review of the Literature显示文摘 | Joost P.H. Drenth T. Wobbes J.J. Bonenkamp Fokko M. Nagengast | 2002 | Digestive Diseases and Sciences2002,,11: | 1 |
| 13 | Surgical management for advanced duodenal adenomatosis and duodenal cancer in Dutch patients with familial adenomatous polyposis: A nationwide retrospective cohort study显示文摘 | Bjorn W.H. van Heumen Marry H. Nieuwenhuis Harry van Goor Lisbeth (E) M.H. Mathus-Vliegen Evelien Dekker Dirk J. Gouma Jan Dees Casper H.J. van Eijck Hans F.A. Vasen Fokko M. Nagengast | 2012 | Surgery2012,,5: | 1 |
| 14 | Video Capsule Endoscopy in Patients With Nonresponsive Celiac Disease显示文摘 | Stijn J. B. Van Weyenberg Fokko Smits Maarten A. J. M. Jacobs Sietze T. Van Turenhout Chris J. Mulder | 2013 | Journal of Clinical Gastroenterology2013,,5: | 1 |