|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer显示文摘 | Fabio Petrocca Rosa Visone Mariadele Rapazzotti Onelli Manisha H. Shah Milena S. Nicoloso Ivana de Martino Dimitrios Iliopoulos Emanuela Pilozzi Chang-Gong Liu Massimo Negrini Luigi Cavazzini Stefano Volinia Hansjuerg Alder Luigi P. Ruco Gustavo Baldassar | 2008 | Cancer Cell2008，，3： | 4 |
| 2 | Human papillomavirus does not have a causal role in colorectal carcinogenesis显示文摘AIM: To investigate the presence of human papillomavirus(HPV) DNA along with the integration,the quantification and the expression of the HPV16 in colorectal cancers.METHODS: A prospective series of colorectal tumors were genotyped for HPV DNA.The clinical and pathological variables of the HPV-positive tumors were compared to those of HPV-negative samples.The integration status of HPV16 was evaluated by calculating E2/E6 ng ratios.HPV16-positive tumors were also evaluated for(1) E2,E4,E5,E6 and E7 viral gene ng quantification;(2) relative quantification compared to W12 cells; and(3) viral E2,E4,E5,E6 and E7 mR NA transcripts by real-time polymerase chain reaction.RESULTS: HPV infection was detected in 16.9% of all tumors examined,and HPV16 was the most frequent type detected(63.6% of positive tissues).Notably,the clinical and pathological features of HPV-positive colorectal cancers were not significantly different than those of HPV-negative cancers(χ2 and t-test for all clinical and pathological features of HPV-positive vs HPV-negative colorectal cancers: p ns).HPV16 DNA was present exclusively in episomal form,and the HPV16 E2,E4,E5,E6 and E7 genes were detected in tracenanogram quantities.Furthermore,the HPV16 genes ranged from 10-3 to 10-9 compared to W12 cells at an episomal stage.Although the extractions were validated by housekeeping gene expression,all the HPV16 positive tissues were transcriptionally inactive for the E2,E4,E5,E6 and E7 mR NAs.CONCLUSION: Based on our results,HPV is unlikely involved in colorectal carcinogenesis. | Laura Lorenzon Francesca Mazzetta Emanuela Pilozzi Giordana Uggeri Maria Rosaria Torrisi Mario Ferri Vincenzo Ziparo Deborah French | 2015 | World Journal of Gastroenterology2015，21，1： | 3 |
| 3 | Type I Gastric Carcinoids: A Prospective Study on Endoscopic Management and Recurrence Rate显示文摘 | Merola Elettra Sbrozzi-vanni Andrea Panzuto Francesco D’ambra Giancarlo Di Giulio Emilio Pilozzi Emanuela Capurso Gabriele Lahner Edith Bordi Cesare Annibale Bruno Delle Fave Gianfranco | 2012 | Neuroendocrinology2012，，3： | 2 |
| 4 | Alteration of Local Microflora and α-defensins Hyper-production in Colonic Adenoma Mucosa显示文摘 | Cristiano Pagnini Vito D. Corleto Maria Luisa Mangoni Emanuela Pilozzi Maria Simona Torre Rodolfo Marchese Antonella Carnuccio Emilio Di Giulio Gianfranco Delle Fave | 2011 | Journal of Clinical Gastroenterology2011，，7： | 2 |
| 5 | Synchronous gastric adenocarcinoma and pancreatic ductal adenocarcinoma显示文摘BACKGROUND:The association between gastric and pancreatic carcinoma is a relatively rare condition.In gastric carcinoma patients,the prevalence of second tumors varies 2.8% to 6.8% according to the reported statistics.Gastric cancer associated with pancreatic cancer is uncommon.METHODS:We report a case of a 73-year-old patient hospitalized for vomiting and weight loss.Esophagogastroduodenoscopy demonstrated an ulcerative lesion of the gastric antrum.Computed tomography and magnetic resonance showed a gastric thickening in the antral and pyloric portion and a nodular mass (3×1.7 cm) in the uncinate portion of the pancreas.RESULTS:The patient underwent pancreaticoduoden-ectomy according to Whipple regional type Ⅰ Fortner.Histological examination of the specimen demonstrated a moderately differentiated adenocarcinoma of the stomach and a poorly differentiated ductal adenocarcinoma of the pancreas.CONCLUSIONS:Long survival is rare in patients with associated gastric and pancreatic cancer.Surgical resection remains the only potentially curative treatment. | Mirko Muroni Francesco D'Angelo Massimo Pezzatini Simone Sebastiani Samantha Noto Emanuela Pilozzi Giovanni Ramacciato | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，1： | 1 |
| 6 | Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up显示文摘 | Edith Lahner Gianluca Esposito Emanuela Pilozzi Flaminia Purchiaroni Vito D Corleto Emilio Di Giulio Bruno Annibale | 2015 | Scandinavian Journal of Gastroenterology2015，，7： | 1 |
| 7 | Epstein–Barr virus (EBV) positive classical Hodgkin lymphoma of Iraqi children: An immunophenotypic and molecular characterization of Hodgkin/Reed‐Sternberg cells显示文摘 | Arianna Di Napoli Mazin F. Al‐Jadiri Caterina Talerico Enrico Duranti Emanuela Pilozzi Pankaj Trivedi Eleni Anastasiadou Adel R. Alsaadawi Amir F. Al‐Darraji Salma A. Al‐Hadad Anna Maria Testi Stefania Uccini Luigi Ruco | 2013 | Pediatr Blood Cancer2013，，12： | 1 |
| 8 | E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer显示文摘 | Fabio Petrocca Rosa Visone Mariadele Rapazzotti Onelli Manisha H. Shah Milena S. Nicoloso Ivana de Martino Dimitrios Iliopoulos Emanuela Pilozzi Chang-Gong Liu Massimo Negrini Luigi Cavazzini Stefano Volinia Hansjuerg Alder Luigi P. Ruco Gustavo Baldassar | 2008 | Cancer Cell2008，，3： | 1 |
| 9 | Number of harvested lymph nodes is the main prognostic factor in Stage IIa colorectal cancer patients显示文摘 | Marco La Torre Laura Lorenzon Emanuela Pilozzi Viola Barucca Marco Cavallini Vincenzo Ziparo Mario Ferri | 2012 | J Surg Oncol2012，，4： | 1 |
| 10 | Large periampullary villous tumor of the duodenum显示文摘 | Marco Cavallini Daniele Cavaniglia Francesco Felicioni Valeria Vitale Emanuela Pilozzi Vincenzo Ziparo | 2007 | Journal of Hepato - Biliary - Pancreatic Surgery2007，，5： | 1 |
| 11 | Reversal of atrophic body gastritis after H. pylori eradication at long-term follow-up显示文摘 | Lucy Vannella Edith Lahner Cesare Bordi Emanuela Pilozzi Emilio Di Giulio Vito D. Corleto John Osborn Gianfranco Delle Fave Bruno Annibale | 2010 | Digestive and Liver Disease2010，，4： | 1 |
| 12 | Is proliferative colonic disease presentation changing?显示文摘AIM:To compare the site,age and gender of cases of colorectal cancer(CRC) and polyps in a single referral center in Rome,Italy,during two periods.METHODS:CRC data were collected from surgery/pathology registers,and polyp data from colonoscopy reports.Patients who met the criteria for familial adenomatous polyposis,hereditary non-polyposis colorectal cancer syndrome or inflammatory bowel disease were excluded from the study.Overlap of patients between the two groups(cancers and polyps) was carefully avoided.Theχ 2 statistical test and a regression analysis were performed.RESULTS:Data from a total of 768 patients(352 and 416 patients,respectively,in periods A and B) who underwent surgery for cancer were collected.During the same time periods,a total of 1693 polyps were analyzed from 978 patients with complete colonoscopies(428 polyps from 273 patients during period A and 1265 polyps from 705 patients during period B).A proximal shift in cancer occurred during the latter years for both sexes,but particularly in males.Proximal cancer increased > 3-fold in period B compared to period A in males [odds ratio(OR) 3.31,95%CI:2.00-5.47;P < 0.0001).A similar proximal shift was observed for polyps,particularly in males(OR 1.87,95%CI:1.23-2.87;P < 0.0038),but also in females(OR 1.62,95%CI:0.96-2.73;P < 0.07).CONCLUSION:The prevalence of proximal proliferative colonic lesions seems to have increased over the last decade,particularly in males. | Vito D Corleto Cristiano Pagnini Maria Sofia Cattaruzza Ermira Zykaj Emilio Di Giulio Giovanna Margagnoni Emanuela Pilozzi Giancarlo D'Ambra Antonietta Lamazza Enrico Fiori Mario Ferri Luigi Masoni Vincenzo Ziparo Bruno Annibale Gianfranco Delle Fave | 2012 | World Journal of Gastroenterology2012，18，45： | 0 |
| 13 | Liver biopsy:analysis of results of two specialist teams显示文摘AIM:To analyze the safety and the adequacy of a sample of liver biopsies(LB)obtained by gastroenterologist(G)and interventional radiologist(IR)teams.METHODS:Medical records of consecutive patients evaluated at our GI unit from 01/01/2004 to31/12/2010 for whom LB was considered necessary to diagnose and/or stage liver disease,both in the setting of day hospital and regular admission(RA) care,were retrieved and the data entered in a database.Patients were divided into two groups:one undergoing an ultrasonography(US)-assisted procedure by the G team and one undergoing US-guided biopsy by the IR team.For the first group,an intercostal approach(US-assisted) and a Menghini modified type needle 16 G(length 90 mm) were used.The IR team used a subcostal approach(US-guided) and a semiautomatic modified Menghini type needle 18 G(length 150 mm).All the biopsies were evaluated for appropriateness according to the current guidelines.The number of portal tracts present in each biopsy was assessed by a revision performed by a single pathologist unaware of the previous pathology report.Clinical,laboratory and demographic patient characteristics,the adverse events rate and the diagnostic adequacy of LB were analyzed.RESULTS:During the study period,226 patients,126 males(56%) and 100 females(44%),underwent LB:167(74%) were carried out by the G team,whereas 59(26%) by the IR team.LB was mostly performed in a day hospital setting by the G team,while IR completed more procedures on inpatients(P < 0.0001).The groups did not differ in median age,body mass index(BMI),presence of comorbidities and coagulation parameters.Complications occurred in 26 patients(16 G team vs 10 IR team,P = 0.15).Most gross samples obtained were considered suitable for basal histological evaluation,with no difference among the two teams(96.4% G team vs 91.5% IR,P = 0.16).However,the samples obtained by the G team had a higher mean number of portal tracts(G team 9.5 ± 4.8; range 1-29 vs IR team 7.8 ± 4.1; range 1-20)(P = 0.0192) and a longer mean length(G team 22 mm ± 8.8 vs IR team 15 ± 6.5 mm)(P = 0.0001).CONCLUSION:LB can be performed with similar outcomes both by G and IR.Use of larger dimension needles allows obtaining better samples,with a similar rate of adverse events. | Giulia Anania Elia Gigante Matteo Piciucchi Emanuela Pilozzi Eugenio Pucci Adriano Maria Pellicelli Carlo Capotondi Michele Rossi Flavia Baccini Giulio Antonelli Paola Begini Gianfranco Delle Fave Massimo Marignani | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，2： | 0 |
| 14 | Is colonoscopy sufficient for colorectal cancer surveillance in all HNPCC patients?显示文摘有有在 hMSH2 的一个变化的结肠癌衬里的世袭 non-polyposis 的 34 岁的男性被报导。尽管有常规 colonoscopic 后续,他得了包含额外的钠区域的盲肠的癌症。由于亚 occlusive 症状,病人被提交推进结肠镜检查,然而没有瘤形成的清楚的证据。计算断层摄影术 CT 扫描此后执行了的多平面的重建揭示了的薄片透壁集中在在盲肠的阀门附近局部性的尺寸的 2.5 厘米。讨论在右边的结肠癌的很高的风险在病人的后续象对进一步的调查的需要一样在 colonoscopic 考试的可靠性上被做,例如世袭 non-polyposis 结肠癌影响的男 hMSH2 搬运人。 | Vito D Corleto Ermira Zykaj Paolo Mercantini Emanuela Pilozzi Michele Rossi Antonella Carnuccio Emilio Di Giulio Vincenzo Ziparo Gianfranco Delle Fave | 2005 | World Journal of Gastroenterology2005，11，47： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员