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478篇 您的检索式:作者名="Volinia"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis显示文摘Tetsuya Ueda Stefano Volinia Hiroshi Okumura Masayoshi Shimizu Cristian Taccioli Simona Rossi Hansjuerg Alder Chang-gong Liu Naohide Oue Wataru Yasui Kazuhiro Yoshida Hiroki Sasaki Sachiyo Nomura Yasuyuki Seto Michio Kaminishi George A Calin Carlo M Croce 2010Lancet Oncology2010,,2:4
3E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer显示文摘Fabio Petrocca Rosa Visone Mariadele Rapazzotti Onelli Manisha H. Shah Milena S. Nicoloso Ivana de Martino Dimitrios Iliopoulos Emanuela Pilozzi Chang-Gong Liu Massimo Negrini Luigi Cavazzini Stefano Volinia Hansjuerg Alder Luigi P. Ruco Gustavo Baldassar 2008Cancer Cell2008,,3:4
4Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice显示文摘Bo Wang Sarmila Majumder Gerard Nuovo Huban Kutay Stefano Volinia Tushar Patel Thomas D. Schmittgen Carlo Croce Kalpana Ghoshal Samson T. Jacob 2009Hepatology2009,,4:3
5Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis显示文摘Tetsuya Ueda Stefano Volinia Hiroshi Okumura Masayoshi Shimizu Cristian Taccioli Simona Rossi Hansjuerg Alder Chang-gong Liu Naohide Oue Wataru Yasui Kazuhiro Yoshida Hiroki Sasaki Sachiyo Nomura Yasuyuki Seto Michio Kaminishi George A Calin Carlo M Croce 2010Lancet Oncology2010,,2:2
6A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘Volinia S Calin GA Liu CG 0,,:2
7Evidence of geneticunderexpression in chorionic villi samples of euploid fetuseswith increased nuchal translucency at 10-11 weeks’gestation显示文摘Farina A Volinia S Arcelli D Prenat Diagn0,26,2:1
8Relation between microRNA expression and progression and prognosis of gastric cancer: a mi- croRNA expression analysis显示文摘Ueda T Volinia S Okumura H 2010Lancet Oncol2010,11,2:1
9The structural ba- sis for 14-3-3 : phosphopeptide binding specificity 显示文摘Yaffe M B Rittinger K Volinia S 1997Cell1997,91,7:1
10A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘Volinia S Calin GA Liu CG 0,,:1
11A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘Volinia S Calin GA Liu CG 2006Proc Natl Acad Sci USA2006,103,7:1
12A microRNA ex- pression signature of human solid tumors defines cancer targets显示文摘Volinia S Calin GA Liu CG 2006Proc Natl Acad Sci USA2006,103,7:1
13MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia显示文摘GARZON R VOLINIA S LIU C G 0,,06:1
14A microRNA expression sig- nature of human solid tumors defines cancer gene targets 显示文摘Volinia S Calin GA Liu CG 2006Proc Natl Acad Sci U S A2006,103,7:1
15A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘VOLINIA S CALIN GA LIU CG 0,,:1
16Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer显示文摘Zhang L Volinia S Bonome T Calin GA Greshock J Yang N 0,,:1
17Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer显示文摘Zhang L Volinia S Bonome T 2008Proc Natl Acad Sci U S A2008,105,19:1
18A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘Volinia S Calin GA Liu CG 2006Proc Natl Acad Sci U S A2006,103,7:1
19Relation between microRNAexpression and progression and prognosis of gastric cancer : ami-croRNA expression analysis显示文摘Ueda T Volinia S Okumura H 2010Lancet Oncol2010,11,2:1
20Relation between microRNA expression and progression and prognosis of gastric cancer:a microRNA expression analysis显示文摘Ueda T Volinia S Okumura H 2010Lancet Oncol2010,11,2:1
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