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| 1 | Duodenal adenocarcinoma: Advances in diagnosis and surgical management显示文摘Duodenal adenocarcinoma is a rare but aggressive malignancy. Given its rarity, previous studies have traditionally combined duodenal adenocarcinoma(DA) with either other periampullary cancers or small bowel adenocarcinomas, limiting the available data to guide treatment decisions. Nevertheless, management primarily involves complete surgical resection when technically feasible. Surgery may require pancreaticoduodenectomy or segmental duodenal resection; either are acceptable options as long as negative margins are achievable and an adequate lymphadenectomy can be performed. Adjuvant chemotherapy and radiation are important components of multi-modality treatment for patients at high risk of recurrence. Further research would benefit from multiinstitutional trials that do not combine DA with other periampullary or small bowel malignancies. The purpose of this article is to perform a comprehensive review of DA with special focus on the surgical management and principles. | Jordan M Cloyd Elizabeth George Brendan C Visser | 2016 | World Journal of Gastrointestinal Surgery2016，8，3： | 13 |
| 2 | 间充质的干细胞的隔离和描述源于人的胎盘组织显示文摘 AIM: To explore the feasibility of placenta tissue as a reliable and efficient source for generating mesenchymal stem cells (MSC). METHODS: MSC were generated from human placenta tissue by enzymatic digestion and mechanical dissociation. The placenta MSC (PLC-MSC) were characterized for expression of cell surface markers, embryonic stem cell (ECS) gene expression and their differentiation ability into adipocytes and osteocytes. The immunosuppressive properties of PLC-MSC on resting and phytohemagglutinin (PHA) stimulated allogenic T cells were assessed by means of cell proliferation via incorporation of tritium thymidine (3H-TdR). RESULTS: The generated PLC-MSC appeared as spindle-shaped cells, expressed common MSC surface markers and ESC transcriptional factors. They also differen-tiated into adipogenic and osteogenic lineages when induced. However, continuous cultivation up to passage 15 caused changes in morphological appearance and cellular senescence, although the stem cell nature of their protein expression was unchanged. In terms of their immunosuppressive properties, PLC-MSC were unable to stimulate resting T cell proliferation; they inhibited the PHA stimulated T cells in a dose dependent manner through cell to cell contact. In our study, MSC generated from human placenta exhibited similar mesenchymal cell surface markers; MSC-like gene expression pattern and MSC-like differentiation potential were comparable to other sources of MSC. CONCLUSION: We suggest that placenta tissues can serve as an alternative source of MSC for future experimental and clinical studies. | Shalini Vellasamy Pratheep Sandrasaigaran Sharmili Vidyadaran Elizabeth George Rajesh Ramasamy | 2012 | World Journal of Stem Cells2012，4，6： | 5 |
| 3 | Single injection of platelet-rich plasma as a novel treatment of carpal tunnel syndrome显示文摘Both in vitro and in vivo experiments have confirmed that platelet-rich plasma has therapeutic effects on many neuropathies, but its effects on carpal tunnel syndrome remain poorly understood. We aimed to investigate whether single injection of platelet-rich plasma can improve the clinical symptoms of carpal tunnel syndrome. Fourteen patients presenting with median nerve injury who had suffered from mild carpal tunnel syndrome for over 3 months were included in this study. Under ultrasound guidance, 1–2 m L of platelet-rich plasma was injected into the region around the median nerve at the proximal edge of the carpal tunnel. At 1 month after single injection of platelet-rich plasma, Visual Analogue Scale results showed that pain almost disappeared in eight patients and it was obviously alleviated in three patients. Simultaneously, the disabilities of the arm, shoulder and hand questionnaire showed that upper limb function was obviously improved. In addition, no ultrasonographic manifestation of the carpal tunnel syndrome was found in five patients during ultrasonographic measurement of the width of the median nerve. During 3-month follow-up, the pain was not greatly alleviated in three patients. These findings show very encouraging mid-term outcomes regarding use of platelet-rich plasma for the treatment of carpal tunnel syndrome. | Michael Alexander Malahias Elizabeth O.Johnson George C.Babis Vasileios S.Nikolaou | 2015 | Neural Regeneration Research2015，10，11： | 4 |
| 4 | Pathways of fear and anxiety in dentistry: A review显示文摘The aim of this article was to analyze the theories underpinning dental fear, anxiety and phobias. To be included, articles must have been published between the years of 1949 and 2013 concerning fears and phobias within dentistry and/or psychiatry. Of 200 articles originally under review, 140 were included and reviewed by the authors.Five specific pathways relating to dental fear and anxiety were identified; Cognitive Conditioning, Informative, Visual Vicarious, Verbal Threat, and Parental. Eight currently accepted management techniques across all dental disciplines for dental fear and anxiety were identified. Further research is required to identify clinical diagnosis and treatment for fears originating from different pathways. | Ava Elizabeth Carter Geoff Carter Mark Boschen Emad AlShwaimi Roy George | 2014 | World Journal of Clinical Cases2014，2，11： | 3 |
| 5 | Parkinson’s Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors显示文摘 | Frank Soldner Dirk Hockemeyer Caroline Beard Qing Gao George W. Bell Elizabeth G. Cook Gunnar Hargus Alexandra Blak Oliver Cooper Maisam Mitalipova Ole Isacson Rudolf Jaenisch | 2009 | Cell2009，，5： | 2 |
| 6 | Acetylation: a novel method for modulation of the immune response following trauma/hemorrhage and inflammatory second hit in animals and humans显示文摘 | Elizabeth A. Sailhamer Yongqing Li Eleanor J. Smith Fahad Shuja Christian Shults Baoling Liu Chad Soupir Marc deMoya George Velmahos Hasan B. Alam | 2008 | Surgery2008，，2： | 2 |
| 7 | Surviving Blood Loss Without Fluid Resuscitation显示文摘 | Christian Shults Elizabeth A. Sailhamer Yongqing Li Baoling Liu Malek Tabbara Muhammad Umar Butt Fahad Shuja Marc deMoya George Velmahos Hasan B. Alam | 2008 | The Journal of Trauma: Injury, Infection, and Critical Care2008，，3： | 2 |
| 8 | Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis显示文摘 | D.Keith George Stefano Goldwurm Graeme A. Macdonald Lex L. Cowley Neal I. Walker Patrick J. Ward Elizabeth C. Jazwinska Lawrie W. Powell | 1998 | Gastroenterology1998，，2： | 2 |
| 9 | Phenolics,tannins,flavonoids and anthocyanins contents influenced antioxidant and anticancer activities of Rubus fruits from Western Ghats,India显示文摘Rubus fruits are rich in nutrition with a wide range of phytochemical and consumed by humans,but many of its wild varieties are not commercially useful.Phytochemical exploration of these wild fruits could improve the commercial usage of these Rubus species.This study focuses to analyze the phytochemical,antioxidant and cytotoxicity of three wild Rubus ellipticus,R.niveus and R.fairholmianus fruits comparatively,which has not revealed.The in vitro antioxidant studies indicated the ethyl acetate and methanol extracts of studied Rubus species competent in scavenging different stable and generated radical.The correlation and regression analysis also statistically supported the contents in the extracts could act against various radicals.Correlation between phytochemical constituent and radical scavenging activity found to be highly positive.The results acquired from this investigation revealed that they are equally competent and could be recommended as dietary supplements or as nutraceuticals. | Kasipandi Muniyandi Elizabeth George Saikumar Sathyanarayanan Blassan P.George Heidi Abrahamse Suman Thamburaj Parimelazhagan Thangaraj | 2019 | Food Science and Human Wellness2019，8，1： | 2 |
| 10 | Divergent apparent temperature sensitivity of terrestrial ecosystem respiration显示文摘Aims Recent studies revealed convergent temperature sensitivity of ecosys-tem respiration(Re)within aquatic ecosystems and between terrestrial and aquatic ecosystems.We do not know yet whether various terres-trial ecosystems have consistent or divergent temperature sensitivity.Here,we synthesized 163 eddy covariance flux sites across the world and examined the global variation of the apparent activation energy(Ea),which characterizes the apparent temperature sensitivity of and its interannual variability(IAV)as well as their controlling factors.Methods We used carbon fluxes and meteorological data across FLUXNET sites to calculate mean annual temperature,tempera-ture range,precipitation,global radiation,potential radiation,gross primary productivity and Re by averaging the daily values over the years in each site.Furthermore,we analyzed the sites with>8 years data to examine the IAV of Ea and calculated the standard deviation of Ea across years at each site to character-ize IAV.Important Findings The results showed a widely global variation of Ea,with significantly lower values in the tropical and subtropical areas than in temperate and boreal areas,and significantly higher values in grasslands and wetlands than that in deciduous broadleaf forests and evergreen for-ests.Globally,spatial variations of Ea were explained by changes in temperature and an index of water availability with differing contribution of each explaining variable among climate zones and biomes.IAV and the corresponding coefficient of variation of Ea decreased with increasing latitude,but increased with radiation and corresponding mean annual temperature.The revealed patterns in the spatial and temporal variations of Ea and its controlling factors indicate divergent temperature sensitivity of Re,which could help to improve our predictive understanding of Re in response to climate change. | Bing Song Shuli Niu Ruisen Luo Yiqi Luo Jiquan Chen Guirui Yu Janusz Olejnik Georg Wohlfahrt Gerard Kiely Asko Noormets Leonardo Montagnani Alessandro Cescatti Vincenzo Magliulo Beverly Elizabeth Law Magnus Lund Andrej Varlagin Antonio Raschi Matthias Peichl Mats BNilsson Lutz Merbold | 2014 | Journal of Plant Ecology2014，7，5： | 2 |
| 11 | Optimization of wheat debranning using laboratory equipment for ethanol production显示文摘Ethanol production from starchy cereal grains is increasing rapidly due to increasing demand for alternative fuels.In Canada,wheat is the primary feedstock in ethanol plants.To improve the productivity of the ethanol plants in terms of product quality and yield,debranning of wheat grains may be employed.Debranning is advantageous in two ways.Firstly,bran removal increases the starch content of the feedstock,improving the fermentation efficiency of the ethanol plants.Secondly,bran,a valuable co-product can be used as an animal feed ingredient.In this study,experiments to optimize the debranning process were carried out using two kinds of abrasive equipment,the Satake and the TADD(tangential abrasive dehulling device)mills.Wheat samples(30 and 200 g)were debranned in the Satake mill at 1215,1412,and 1515 r/min rotational speeds,30,36,and 40 grit sizes,and 30,60,and 90 s retention times,and in the TADD mill at 900 r/min rotational speed,30,36,50,and 80 grit sizes,and 120,180,240,and 300 s retention times.In addition to debranning efficiency,the starch separation efficiencies of the two mills were calculated in different debranning conditions.In the Satake mill,the 30 g and 200 g sample size,1412 r/min and 1515 r/min rotational speeds,all grit sizes,and 60 s of retention time demonstrated the highest debranning efficiency.Correspondingly,optimal results in the TADD mill were obtained with 200 g sample size,900 r/min rotational speed,50 and 80 grit sizes,and 180 s and 240 s retention times.However,based on the experimental results,Satake mill provided better debranning values compared to the TADD mill.The starch separation efficiency values supported these results. | Elizabeth George Bayartoghtok Rentsen Lope G.Tabil Venkatesh Meda | 2014 | International Journal of Agricultural and Biological Engineering2014，7，6： | 2 |
| 12 | Testing a model of CO 2 , water and energy exchange in Great Plains tallgrass prairie and wheat ecosystems显示文摘 | Niall P. Hanan Joseph A. Berry Shashi B. Verma Elizabeth A. Walter-Shea Andrew E. Suyker George G. Burba A. Scott Denning | 2005 | Agricultural and Forest Meteorology2005，，3： | 2 |
| 13 | Histone deacetylase inhibitors prevent apoptosis following lethal hemorrhagic shock in rodent kidney cells显示文摘 | Nikolaos Zacharias Elizabeth A. Sailhamer Yongqing Li Baoling Liu Muhammad U. Butt Fahad Shuja George C. Velmahos Marc de Moya Hasan B. Alam | 2010 | Resuscitation2010，，1： | 2 |
| 14 | Petrographic Evaluation of the Ranks and Technological Applications of Some Coal Deposits in the Anambra Basin and Middle Benue Trough of Nigeria显示文摘 | Elizabeth Olive Wuyep Nuhu George Obaje | 2012 | Journal of Earth Science and Engineering2012，2，4： | 2 |
| 15 | An appraisal of lymph node ratio in colon and rectal cancer: not one size fits all显示文摘 | M. Medani Niall Kelly George Samaha G. Duff Vourneen Healy Elizabeth Mulcahy Eoghan Condon David Waldron Jean Saunders J. Calvin Coffey | 2013 | International Journal of Colorectal Disease2013，，10： | 1 |
| 16 | The meaning and measurement of age identity显示文摘 | Linda K. George Elizabeth J. Mutran Margaret R. Pennybacker | 1980 | Experimental Aging Research1980，，3： | 1 |
| 17 | Proteomics Analysis Identifies Molecular Targets Related to Diabetes Mellitus- associated Bladder Dysfunction显示文摘 | Elizabeth Yohannes Jinsook Chang George J Christ | 2008 | Molecular & Cellular Proteomics2008，7，： | 1 |
| 18 | A Methodology for Profiling Consumers'Decision - Marking Styles 显示文摘 | Sproles George B Kendall Elizabeth L | 1986 | Journal of Consumer Affairs1986，20，2： | 1 |
| 19 | Consumer Decision - Making Styles as a Function of Individual Learning Styles 显示文摘 | Sproles Elizabeth Kendall Sproles George B | 1990 | Journal of Consumer Affairs1990，24，1： | 1 |
| 20 | Molecular cloning and characterization of Toll-like receptors 1-10 in sheep显示文摘 | Jung-Su Chang George C. Russell Oliver Jann Elizabeth J. Glass Dirk Werling David M. Haig | 2008 | Veterinary Immunology and Immunopathology2008，，1： | 1 |
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