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| 1 | Prevalence of H pylori associated 'high risk gastritis' for development of gastric cancer in patients with normal endoscopic findings显示文摘AIM: To investigate the prevalence of H pylori associated corpus-predominant gastritis (CPG) or pangastritis, severe atrophy, and intestinal metaplasia (IM) in patients without any signifi cant abnormal fi ndings during upper- GI endoscopy. METHODS: Gastric biopsies from 3548 patients were obtained during upper GI-endoscopy in a 4-year period. Two biopsies from antrum and corpus were histologically assessed according to the updated Sydney-System. Eight hundred and forty-fi ve patients (mean age 54.8 ± 2.8 years) with H pylori infection and no peptic ulcer or abnormal gross fi ndings in the stomach were identifi ed and analyzed according to gastritis phenotypes using different scoring systems. RESULTS: The prevalence of severe H pylori associated changes like pangastritis, CPG, IM, and severe atrophy increased with age, reaching a level of 20% in patients of the age group over 45 years. No differences in frequencies between genders were observed. The prevalence of IM had the highest increase, being 4-fold higher at the age of 65 years versus in individuals less than 45 years. CONCLUSION: The prevalence of gastritis featuring at risk for cancer development increases with age. These findings reinforce the necessity for the histological assessment, even in subjects with normal endoscopic appearance. The age-dependent increase in prevalence of severe histopathological changes in gastric mucosa, however, does not allow estimating the individual risk forgastric cancer development-only a proper follow-up can provide this information. | Andreas Leodolter Matthias P Ebert Ulrich Peitz Kathlen Wolle Stefan Kahl Michael Vieth Peter Malfertheiner | 2006 | World Journal of Gastroenterology2006，12，34： | 4 |
| 2 | Expression of metallothionein Ⅱ in intestinal metaplasia,dysplasia,and gastric cancer显示文摘 | Matthias P A Ebert Thomas Günther Juliane Hoffmann | 2000 | Cancer Research2000，60，： | 1 |
| 3 | Mast cells as rapid innate sensors of cytomegalovirus by TLR3/TRIF signaling-dependent and -independent mechanisms显示文摘简明比喻, ‘免疫系统装载了 gun' ,被用来在能在需求上几乎立即被释放与侵略者作斗争的能分泌的小粒由于他们大量有势力支持 inflammatory 和抗菌剂调停人的存储描述桅杆房间(MC ) 的角色。在主人环境定位了边界并且与模式识别受体的一个军火库装备了, MC 被注定是渗透 endothelial 和上皮的表面的病原体的快速的天生的传感器。尽管在抗菌剂和 antiparasitic 防卫的 MC 的重要性长被欣赏了,他们在对病毒的感染发出报警的角色仅仅最近被注意了。 cytomegalovirus ( CMV )上的工作在鼠科的模型的感染在在 CMV 的天生、适应的有免疫力的监视之间的新奇串音轴作为播放器揭示了 MC 在 MC ,它与 MC degranulation 和 chemokine CCL5 的版本被联系的那感染,提高保护的 CD8 T 房间的招募到病毒复制的血管外的地点,明确地到肺 interstitium 和牙槽的上皮。这里,我们由响应主人感染为 MC 激活和作为结果的 degranulation 调查条件阐述了这些研究。令人惊讶地,数据揭示了 MC 激活的二个时间地并且机械学地不同的波浪:取决于 TLR3/TRIF 发信号并且由没包含 TLR3/TRIF 发信号的 MC 的直接感染推迟了激活的几乎立刻的间接激活。产出有选择地从 MC 发源的表示 eGFP 记者病毒的房间类型特定的 Cre 再结合识别了是的 MC 一在 vivo 新,生产鼠科的 CMV 感染的第一点击的目标房间。 | Marc Becker Niels AW Lemmermann Stefan Ebert Pamela Baars Angelique Renzaho Jurgen Podlech Michael Stassen Matthias J Reddehase | 2015 | Cellular & Molecular Immunology2015，12，2： | 1 |
| 4 | Molecular screening of gastric cancer by proteome analysis显示文摘 | Matthias P.A. Ebert Christoph R?cken | 2006 | European Journal of Gastroenterology & Hepatology2006，，8： | 1 |
| 5 | Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2′-deoxycytidine显示文摘 | Jie Chen Christoph R?cken Ludger Klein-Hitpass Tobias G?tze Andreas Leodolter Peter Malfertheiner Matthias P.A. Ebert | 2004 | Clinical & Experimental Metastasis2004，，5： | 1 |
| 6 | Overexpression of Platelet-Derived Growth Factor (PDGF) B Chain and Type β PDGF Receptor in Human Chronic Pancreatitis显示文摘 | Matthias Ebert Hans-Udo Kasper Sara Hernberg Helmut Friess Markus W. Buchler Albert Roessner Murray Korc Peter Malfertheiner | 1998 | Digestive Diseases and Sciences1998，，3： | 1 |
| 7 | Long-term outcome of endoscopic and/or percutaneous transhepatic therapy in patients with biliary stricture after orthotopic liver transplantation显示文摘 | Andreas Weber Christian Prinz Carlos Gerngro? Leopold Ludwig Wolfgang Huber Bruno Neu Matthias P. Ebert Alexander Meining Hans Weidenbach Roland M. Schmid Ewert Schulte-Frohlinde | 2009 | Journal of Gastroenterology2009，，12： | 1 |
| 8 | Adenocarcinomas of the Esophagogastric Junction Are More Likely to Respond to Preoperative Chemotherapy than Distal Gastric Cancer显示文摘 | Daniel Reim Ralf Gertler Alexander Novotny Karen Becker Christian Büschenfelde Matthias Ebert Martin Dobritz Rupert Langer Heinz Hoefler Helmut Friess Christoph Schumacher | 2012 | Annals of Surgical Oncology2012，，7： | 1 |
| 9 | Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2′-deoxycytidine显示文摘 | Jie Chen Christoph R?cken Ludger Klein-Hitpass Tobias G?tze Andreas Leodolter Peter Malfertheiner Matthias P.A. Ebert | 2004 | Clinical & Experimental Metastasis2004，，5： | 1 |
| 10 | Serum levels of irisin in gestational diabetes mellitus during pregnancy and after delivery显示文摘 | Thomas Ebert Holger Stepan Susanne Schrey Susan Kralisch Janka Hindricks Lisa Hopf Martin Platz Ulrike Lossner Beate Jessnitzer Sascha Drewlo Matthias Blüher Michael Stumvoll Mathias Fasshauer | 2013 | Cytokine2013，，： | 1 |
| 11 | Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection显示文摘 | Stefan Ebert Jürgen Podlech Dorothea Gillert-Marien Kerstin M. Gergely Julia K. Büttner Annette Fink Kirsten Freitag Doris Thomas Matthias J. Reddehase Rafaela Holtappels | 2012 | Medical Microbiology and Immunology2012，，4： | 1 |
| 12 | Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal canaers显示文摘 | Matthias PA Ebert W Suzanne H | 2005 | Neoplasia2005，7，： | 1 |
| 13 | Investigations of the influence of dicing techniques on the strength properties of thin silicon 显示文摘 | Stephan Schoenfelder Matthias Ebert Christof Landesberge Karlheinz Book Jorg Bagdahn | 2007 | Microelectronics Reliability2007，47，： | 1 |
| 14 | Investigations of the influence of dicing techniques on the strength properties of thin silicon显示文摘 | Schoenfelder Stephan Ebert Matthias Landesberger Christof | 2007 | Microelectronics Reliability2007，47，23： | 1 |
| 15 | Generation of cytokine-induced killer cells using exogenous interleukin-2, -7 or -12显示文摘 | Birgit Zoll Petja Lefterova Markus Csipai Sigrun Finke Beate Trojaneck Oliver Ebert Bettina Micka Klaus Roigk Matthias Fehlinger Gabriele D. Schmidt-Wolf Dieter Huhn Ingo G. H. Schmidt-Wolf | 1998 | Cancer Immunology Immunotherapy1998，，4： | 1 |
| 16 | Expression of caveolin-1 in gastrointestinal and extraintestinal cancers显示文摘 | Márk Juhász Jie Chen Zsolt Tulassay Peter Malfertheiner Matthias P. A. Ebert | 2003 | Journal of Cancer Research and Clinical Oncology2003，，9： | 1 |
| 17 | Increased β-catenin mRNA levels and mutational alterations of the APC and β-catenin gene are present in intestinaltype gastric cancer显示文摘 | Matthias PA Ebert Guo Fei Sabine Kahmann | 2002 | Carcinogenesis2002，23，1： | 1 |
| 18 | Loss of Beta-catenin expression in metastatic gastric cancer 显示文摘 | Matthias PA Ebert Jun Yu Juliane Hoffmann | 2003 | J Clin Oncol2003，21，9： | 1 |
| 19 | Long-term outcome of endoscopic and/or percutaneous transhepatic therapy in patients with biliary stricture after orthotopic liver transplantation显示文摘 | Andreas Weber Christian Prinz Carlos Gerngro? Leopold Ludwig Wolfgang Huber Bruno Neu Matthias P. Ebert Alexander Meining Hans Weidenbach Roland M. Schmid Ewert Schulte-Frohlinde | 2009 | Journal of Gastroenterology2009，，12： | 1 |
| 20 | A numerical and experimental comparison of heat transfer in a quasi two-dimensional packed bed显示文摘Heat transfer plays a major role in many industrial processes taking place in packed beds.An accurate and reliable simulation of the heat exchange between particles is therefore crucial for a reliable operation and to optimize the processes in the bed.The discrete ordinates method(DOM)provides an established numerical technique to model radiative heat transfer in granular media that offers the possibility to consider the directional dependence of the radiation propagation.In this work,DOM is compared with Monte Carlo ray tracing,which provides an alternative method for heat transfer simulations.Geomet-rically simple configurations are used to investigate the influence of the angular discretization on the accuracy of the results and the computation time in both methods.The obtained insights are then transferred to a more complex configuration of a quasi two-dimensional test rig consisting of metal rods for which also experimental results are available.Our results show that both DOM and Monte Carlo ray tracing allow for an accurate simulation of heat transfer in packed beds.Monte Carlo ray tracing requires thereby computation times that are surprisingly competitive(although still somewhat slower)compared to DOM and allows for an easier computation of highly accurate reference solutions.In our preliminary comparison to the experimental test rig,Monte Carlo ray tracing also provides the advantage that it can more easily model highly specular materials such as stainless steel.Both methods are comparable for diffuse materials such as magnesium oxide. | Matthias Tyslik Mirko Ebert Martin Schiemann Siegmar Wirtz Christian Lessig | 2024 | Particuology2024，84，1： | 0 |
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