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| 1 | Karyotype Stability and Unbiased Fractionation in the Paleo-Allotetraploid Cucurbita Genomes显示文摘 | Honghe Sun Shan WU Guoyu Zhang Chen Jiao Shaogui Guo Yi Ren Jie Zhang Haiying Zhang Guoyi Gong Zhangcai Jia Fan Zhang Jiaxing Tian William J. Lucas Jeff J. Doyle Haizhen Li Zhangjun Fei Yong Xu | 2017 | Molecular Plant2017，10，10： | 33 |
| 2 | 核表达CAMTA1可用于鉴别上皮样血管内皮细胞瘤与其组织学类似的肿瘤显示文摘上皮样血管内皮细胞瘤(EHE)是一种血管内皮细胞起源的恶性肿瘤,其特点是染色体1p36.3和3q25区域多次易位,导致约90%的病例中出现WWTR1-CAMTA1基因融合;少数病例(〈5%)出现YAP1-TFE3基因融合。WWTR1-CAMTA1融合基因导致这两种蛋白过表达。WWTR1蛋白在多种细胞中表达,而CAMTA1通常仅限于脑组织中表达。 | Doyle L A Fletcher C D Hornick J L 魏建国 许春伟 | 2016 | 临床与实验病理学杂志2016，32，6： | 16 |
| 3 | 缺血性脑损伤机制的研究进展显示文摘在美国,中风是致死第三大因素,致残的首要因素。中风引起的脑损伤由有着复杂相互作用的多个通路引起,包括兴奋性神经毒性,酸中毒,电解质失衡,围梗死去极化,氧化和硝化应激,炎症反应和细胞凋亡。对于中风而言,现在有效的治疗途径很少。那么,探索新的治疗方法就需要对各种脑缺血损伤机制的全面了解。本文讨论基本的中风的病理生理过程,揭示治疗干预可靶向复杂通路。 | Doyle KP Simon RP Stenztl-Peore MP 王竞 杜俊蓉 | 2008 | 国际药学研究杂志2008，35，4： | 14 |
| 4 | Determinants of weaknesses in internal control over financial reporting显示文摘 | Jeffrey Doyle Weili Ge Sarah McVay | 2006 | Journal of Accounting and Economics2006，，1： | 9 |
| 5 | BCRP基因在非小细胞肺癌组织和非癌肺组织中的表达及意义显示文摘目的:进一步研究从人类乳腺癌细胞株 (MCF-7/AdrVp)中克隆出的、对蒽环类抗癌药耐药的 BCRP基因在非癌肺组织及非小细胞肺癌组织中的表达。方法:从术后即刻获得的正常肺组织和有活力的非小细胞肺癌组织新鲜标本中及时提取细胞总 RNA,通过 RT-PCR及 PCR法获得并扩增 BCRP基因的 cDNA产物,再经凝胶电泳分离 BCRP基因 cDNA带,然后再通过转膜技术把这些 BCRP基因 cDNA产物转移到杂交膜上,用 Southern blot杂交技术检测 BCRP基因的表达程度。结果:细胞总 RNA分别从 8个只有肺癌组织标本和 12对同时获取的肺癌组织及非癌肺组织标本中成功提取,然后用变性凝胶电泳鉴定提取 RNA的质量。其中 4例标本因术中缺血时间太长,或有坏死炎症或术前放化疗等原因,所提 RNA有降解而放弃进一步的检测。通过 RT-PCR及 PCR方法从 16例可用标本中获得并扩增 BCRP基因的 cDNA产物,再通过转膜及 Southern blot杂交技术,最终发现 BCRP基因在正常肺组织中均有不同程度的表达( 10/10),而在非小细胞肺癌组织标本中只有一半病人的标本有不同程度的表达 (8/16)。结论: BCRP基因可能是一个在非癌肺组织中常规表达的基因,而在部分病人的肺癌组织中可能此基因有缺失或被抑制。因此。 | 毛友生 Austin Doyle Weidong Yang Yuetong Wei Mark J.Krasna Douglas D.Ross | 2001 | 癌症2001，20，3： | 9 |
| 6 | 基于Lattice Boltzmann方法的页岩张性裂缝渗流特征研究显示文摘为深入了解张性裂缝结构中流体渗流特征,采用物理实验和数值模拟相结合的方法,系统研究流体在页岩张性裂缝中的渗流特征。将Barnett页岩岩心劈裂成张性裂缝,并采集裂缝面数据,将其作为物理模型,同时采用LBM-BKG方法 D3Q19模型研究流体在张性裂缝中的流动。研究尺度依次为整体、截面、截线、离散单元体,考察各尺度下渗流场特征参数分布,并分析原因。研究表明:整体上,沿渗流横向和纵向上压力均呈线性分布,横向各截线上压力呈波动式线性分布,纵向截线上压力分布呈非线性;缝面端部局部区域会产生回流区,回流区与粗糙性及粗糙性变化程度有关;近平均速度的速度等值面间基本呈平行分布,速度较大时,等值面基本对应于端面相对平缓的区域;沿同一流线,渗流速度略有差别;整体渗流为稳态,不代表渗流场各处速度相等,离散的渗流单元体的渗流速度各不相同;三维粗糙性造成了渗流速度的三维分布,但主要以渗流方向和垂向上渗流速度为主。该项研究对深入理解页岩等裂缝发育储层的裂缝系统渗流具有重要意义。 | 曲冠政 周德胜 彭娇 Randy Doyle Hazlett Siwei Wu | 2018 | 特种油气藏2018，25，1： | 7 |
| 7 | The application of carbon materials in nonaqueous Na‐O2 batteries显示文摘Na‐O2 batteries are advantageous as the candidates of next‐generation electric vehicles due to their ultrahigh theoretical energy density and have attracted enormous attention recently.Tremendous efforts have been devoted to improve the Na‐O2 battery performance by designing advanced electrodes with various carbonbased materials.Carbon materials used in Na‐O2 batteries not only function as the air electrode to provide active sites and accommodate discharge products but also as Na anode protectors against dendrite growth and chemical/electrochemical corrosion.In this review,we mainly focus on the application of various carbonbased materials in Na‐O2 batteries and highlight their advances.The scientific understanding on the fundamental design of the material microstructure and chemistry in relation to the battery performance are summarized.Finally,perspectives on enhancing the overall battery performance based on the optimization and rational design of carbon‐based cell components are also briefly anticipated. | Xiaoting Lin Qian Sun Kieran Doyle Davis Ruying Li Xueliang Sun | 2019 | Carbon Energy2019，1，2： | 5 |
| 8 | 冷却肉中细菌病原体的存活和生长显示文摘 | M.Ellin Doyle 柳飞 | 2005 | 肉类研究2005，19，6： | 5 |
| 9 | 关于与青光眼疾病严重性相关的资源使用和成本的一项多中心回顾性试验研究显示文摘目的:调查在不同疾病严重程度上青光眼治疗的资源消耗和直接成本。
设计:基于医学档案综述的观察性、回顾性的队列研究。 | Paul P. Lee John G. Walt John J. Doyle Sameer V. Kotak Stacy J. Evans Donald L. Budenz Philip P. Chen Anne L. Coleman Robert M. Feldman HenRY D. Jampel L.Jay Katz Richard P.Mills Jonathan S.Myers Robert J.Noecker Jody R.Piltz-Seymour Robert R.Ritch Paul N.Schacknow Janet B.Serle Gary L.Trick 范翔(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，4： | 4 |
| 10 | Analysis of Open Access Landscape显示文摘This paper is created by bounding 5 editorials of Public Library of Science (PLoS ) which have written on various aspects of open access. It covers wide range topics of important open access issues, such as from paying for open access to copyright to open access as a public issue, which may be more or less of interest of our audience. | Helen Doyle Andy Gass Debra Lappin Rebecea Kennison | 2005 | 图书情报工作2005，49，12： | 4 |
| 11 | Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series显示文摘A case series was used to evaluate the efficacy of halffluence photodynamic therapy(PDT) for chronic central serous chorioretinopathy(CSCR). Patients were treated with standard-dose verteporfin and half-fluence PDT. Totally 13 eyes from 11 patients were included. The mean patient age was 52.0 y. There was a mean reduction in central retinal thickness of 107.0 microns. Totally 7/13 eyes(53.8%) achieved resolution of subretinal fluid(SRF) on optical coherence tomography(OCT) scan after 1 treatment with PDT. Four eyes had further treatment with PDT; of these 1 eye achieved resolution of SRF. Seven of the 13 eyes(53.8%) achieved an improvement of more than 5 ETDRS letters. One patient experienced acute macula oedema 1 d post PDT treatment. These results support the hypothesis that half-fluence PDT can have a positive effect in chronic CSCR for a gain in visual acuity and reduction in sub-retinal fluid. Acute macula oedema is a rare but potential adverse effect of half-fluence PDT. | Jennifer Doyle Bhaskar Gupta Irfan Tahir | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 3 |
| 12 | Targeting DNA Double-Strand Breaks with TAL Effector Nucleases显示文摘 | Christian Michelle Cermak Tomas Doyle Erin L Schmidt Clarice Zhang Feng Hummel Aaron Bogdanove Adam J Voytas Daniel F | 2010 | Genetics2010，，2： | 3 |
| 13 | 铟酞菁/聚甲基丙烯酸甲酯复合物固体光限幅器性能显示文摘将在溶液中表现出优良非线性光学和光限幅性能的铟酞菁及其二聚物嵌入到非光学活性的聚甲基丙烯酸甲酯(PMMA)中,用传统的旋转涂膜法制备得到具有较高光学质量的复合物薄膜,用开孔Z-扫描方法在532nm处研究了复合物薄膜材料的线性光学和非线性光学性能.结果表明,无论是铟酞菁单体还是轴向氧桥联的铟酞菁二聚物,其PMMA复合材料的光限幅性能均显著优于相应的酞菁分子在溶液中的光限幅性能. | 刘莹 陈彧 冯苗 林楹 Doyle J.J. Blau W.J. 蔡良珍 | 2007 | 高等学校化学学报2007，28，11： | 3 |
| 14 | An assessment of direct and indirect effects of climate change for populations of the Rocky Mountain Apollo butterfly ( Parnassius smintheus Doubleday)显示文摘气候变化正在发生,昆虫正在反应。为生态学家和经理的当前的挑战正在预言有机体怎么将对继续气候变化并且决定怎么减轻潜在的否定效果作出回应。与为包含种类的分发的气候变化的宽广规模预言相对照,在这篇文章,我们加亮岩石山阿波罗蝴蝶(Parnassius smintheus Doubleday ) 的本地人口在被预言对气候变化作出回应的许多方法。用在过去的 15 年收集的试验性、观察的数据,我们详细说明直接、间接的效果。另外,我们鉴别在我们限制能力预言人口怎么将对气候作出回应的知识的限制变化。一些变化例如更温暖的冬季温度,可以有有益的效果;然而,大多数气候变化的效果将是有害的。在雪盖子的可变性在 overwintering 期间,时期和产地损失由于森林侵入有最大的潜在的否定效果。 | Stephen F. Matter Amanda Doyle Kurt Illerbrun Jeanette Wheeler Jens Roland | 2011 | Insect Science2011，18，4： | 3 |
| 15 | PREDICTING THE DEPTH OF EROSION IN RESERVOIRS FOLLOWING DAM REMOVAL USING BANK STABILITY ANALYSIS显示文摘Dam removal has emerged in the U.S. as a critical concern for river management. Of particular interest is predicting the quantity of sediment that will be eroded from a reservoir following dam removal, which necessitates predicting the geometry a channel will approach as it forms in the reservoir. The geometry and sediment characteristics of the Koshkonong River were measured as it adjusted to the removal of the Rockdale Dam. Bank stability modeling was used as a tool for predicting the maximum depth of the evolving channel and general agreement was found between depths predicted with the model and those observed up to one year following dam removal. Model sensitivity analysis showed strong control of bank heights by groundwater levels in the reservoir sediment, as well as some control by vegetation established on the sediment surface. Long-term monitoring is needed to assess the accuracy of the model, but preliminary agreement is encouraging for applying this model and similar models to future dam removals. | Martin W. DOYLE Emily H. STANLEY Andy R. SELLE John M. STOFLETH Jon M. HARBOR | 2003 | International Journal of Sediment Research2003，18，2： | 3 |
| 16 | Characterising acute ischaemic stroke thrombi:insights from histology,imaging and emerging impedance-based technologies显示文摘Treatment of acute ischaemic stroke(AIS)focuses on rapid recanalisation of the occluded artery.In recent years,advent of mechanical thrombectomy devices and new procedures have accelerated the analysis of thrombi retrieved during the endovascular thrombectomy procedure.Despite ongoing developments and progress in AIS imaging techniques,it is not yet possible to conclude definitively regarding thrombus characteristics that could advise on the probable efficacy of thrombolysis or thrombectomy in advance of treatment.Intraprocedural devices with dignostic capabilities or new clinical imaging approaches are needed for better treatment of AIS patients.In this review,what is known about the composition of the thrombi that cause strokes and the evidence that thrombus composition has an impact on success of acute stroke treatment has been examined.This review also discusses the evidence that AIS thrombus composition varies with aetiology,questioning if suspected aetiology could be a useful indicator to stroke physicians to help decide the best acute course of treatment.Furthermore,this review discusses the evidence that current widely used radiological imaging tools can predict thrombus composition.Further use of new emerging technologies based on bioimpedance,as imaging modalities for diagnosing AIS and new medical device tools for detecting thrombus composition in situ has been introduced.Whether bioimpedance would be beneficial for gaining new insights into in situ thrombus composition that could guide choice of optimum treatment approach is also reviewed. | Smita Patil Jean Darcourt Pierluca Messina Franz Bozsak Christophe Cognard Karen Doyle | 2022 | Stroke & Vascular Neurology2022，7，4： | 3 |
| 17 | Probiotic Bacteria Enhance Murine and Human Intestinal Epithelial Barrier Function显示文摘 | Karen Madsen Anthony Cornish Paul Soper Conor McKaigney Humberto Jijon Christine Yachimec Jason Doyle Lawrence Jewell Claudio De Simone | 2001 | Gastroenterology2001，，3： | 2 |
| 18 | The signaling adaptors and pathways activated by TNF superfamily显示文摘 | Paul W Dempsey Sean E Doyle Jeannie Q He Genhong Cheng | 2003 | Cytokine and Growth Factor Reviews2003，，3： | 2 |
| 19 | Characterizing the allopolyploid species among the wild relatives of soybean: Utility of reduced representation genotyping methodologies显示文摘异源是在许多被子植物类的一个普通特征。在类 Glycine 的大豆的长期的野亲戚最近包括至少九形成(在最后百万年以内) allopolyploid taxa。这研究用染色体宽的单个核苷酸多型性(SNP ) 和网络分析检验了三 allopolyploid 和四双祖先 taxa。由定序的 Genotyping (GBS ) 被用来产生 SNP,结果与从 transcriptome 数据的以前的分析相比。定序的 Illumina 的三条小巷没有失踪的数据越过八 taxa 为 70 就职和 22806 SNP 的排列生产了遗传型。与网络分析相结合的排列从以前的研究证实了结果。另外, GBS 使可能的扩大采样鉴别也被分类或取样那的就职来自混合种子股票。最吸引人的结果是在 allopolyploids 从特别亚群被导出的双 taxa,和可能性的以内的以前未被认出的基础的发现。进 SNP 的 allopolyploid SNP 的分离源于 homoeologous 祖先种类显示 allopolyploids 不再与他们的双祖先分享遗传型但是从要遮住的直接祖先遗传型为信号长足够独立演变。 | Sue Sherman-Broyles Aureliano Bombarely Jeff Doyle | 2017 | Journal of Systematics and Evolution2017，55，4： | 2 |
| 20 | An overview of mortality and sequelae of preterm birth from infancy to adulthood显示文摘 | Saroj Saigal Lex W Doyle | 2008 | The Lancet2008，，9608： | 2 |
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