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| 1 | Patterns of Herbal Combination for the Treatment of Insomnia Commonly Employed by Highly Experienced Chinese Medicine Physicians显示文摘Objective:To explore the most effective herbal combinations commonly used by highly experienced Chinese medicine(CM) physicians for the treatment of insomnia.Methods:We collected and analyzed data related to insomnia treatment from the clinics of 7 highly experienced CM physicians in Beijing.The sample included 162 patients and 460 consultations in total.Patient outcomes,such as sleep quality and sleep time per day,were manually collected from the medical records by trained CM clinicians.Three data mining methods,support vector machine(SVM),logistic regression and decision tree,and multifactor dimensionality reduction(MDR),were used to determine and confirm the herbal combinations that resulted in positive outcomes in patients suffering from insomnia.Results:Results show that MDR is the most efficient method to predict the effective herbal combinations.Using the MDR model,we identified several combinations of herbs with 100%positive outcomes,such as stir-fried spine date seed,Szechwan lovage rhizome,and prepared thinleaf milkwort root;white peony root,golden thread,and stir-fried spine date seed;and Asiatic cornelian cherry fruit with fresh rehmannia.Conclusions:Results indicate that herbal combinations are effective treatments for patients with insomnia compared with individual herbs.It is also shown that MDR is a potent data mining method to identify the herbal combination with high rates of positive outcome. | 周雪忠 张润顺 Shah Jatin Raiqor Dimple 王映辉 Pietrobon Ricardo 刘保延 陈洁 朱建贵 高荣林 | 2011 | Chinese Journal of Integrative Medicine2011，17，9： | 12 |
| 2 | Lubiprostone used with polyethylene glycol in diabetic patients enhances colonoscopy preparation quality显示文摘AIM: To assess the additive effect of lubiprostone on the quality of colon preparation in diabetics given single-dosed polyethylene glycol electrolyte(PEG)for colonoscopy.METHODS:This was an investigator-initiated,singlecenter,single-blinded prospective trial comparing the efficacy of L+PEG to PEG alone on colon preparation quality in diabetics undergoing screening colonoscopy.The study was approved by our institution’s IRB.The PEG was given as a single-dose to address patientcompliance concerns voiced by our IRB with splitdosing.All patients received only clear liquids the day prior to colonoscopy.Experimental group(Grp L)received PEG+1 dose L 2 h prior to and 2 h after PEG completion.Control group(Grp C)received only PEG the evening prior to the colonoscopy.Patients were randomly assigned to one of the 2 groups.The endoscopist was blinded to which colon prep was given and all colonoscopies were complete.Upon colonoscopy completion,the endoscopist rated the colon prep-quality by a validated 5-point Likert scale(1-excellent to 5-inadequate).RESULTS:Sixty patients were enrolled in the study;30 Grp L and 30 Grp C.Overall,patients were excluded due to study non-completion in 12(41%)Grp L and 5(17%) Grp C,P=0.04.Average colon preparation score Grp L =2.47 and Grp C=3.00,P=0.09.Although this was not statistically significant,there was a trend towards improved colon prep in Grp L.Statistical significance may have been achieved if completion rates had been similar between both study groups.CONCLUSION:Use of 2-L capsules with PEG resulted in a trend towards improved colon prep over PEG alone in diabetic patients when given as a single-dose regimen. | Erika Grigg Moonkyung C Schubert Joshua Hall Fadi Rahhal Dimple Raina Subbaramiah Sridhar Sherman M Chamberlain | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，7： | 5 |
| 3 | The impact of electronic word-of-mouth communication: A literature analysis and integrative model显示文摘 | Christy M.K. Cheung Dimple R. Thadani | 2012 | Decision Support Systems2012，，1： | 2 |
| 4 | Estrogen Receptor Beta ( ERβ ) in endometrial simple hyperplasia and endometrioid carcinoma 显示文摘 | Dimple C Radhika S Sujata G | 2008 | Appl Immunohistochem Mol Morphol2008，16，6： | 1 |
| 5 | Volatilisation and catalytic effects of alkali and alkaline earth metallic species during the pyrolysis and gasification of Victorian brown coal. Part II. Effects of chemical form and valence显示文摘 | Dimple M. Quyn Hongwei Wu Sankar P. Bhattacharya Chun-Zhu Li | 2001 | Fuel2001，，： | 1 |
| 6 | Lipoblastoma and Lipoblastomatosis in Infancy and Childhood: Histopathologic, Ultrastructural, and Cytogenetic Features显示文摘 | John Hicks Anthony Dilley Dimple Patel James Barrish Shen-Hua Zhu Mary Brandt | 2001 | Ultrastructural Pathology2001，，4： | 1 |
| 7 | Role of PELP1/ MNAR signaling in ovarian tumorigenesis显示文摘 | DIMPLE C NAIR S S RAJHANS R | 2008 | Cancer Re search2008，68，12： | 1 |
| 8 | Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics显示文摘 | Ekta Khurana Yao Fu Vincenza Colonna Xinmeng Jasmine Mu Hyun Min Kang Tuuli Lappalainen Andrea Sboner Lucas Lochovsky Jieming Chen Arif Harmanci Jishnu Das Alexej Abyzov Suganthi Balasubramanian Kathryn Beal Dimple Chakravarty Daniel Challis Yuan Chen Dec | 2013 | Science2013，，6154： | 1 |
| 9 | Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1显示文摘 | Prabhat Kumar Purbey Sunita Singh Dimple Notani | 2009 | Molecular and Cellular Biology2009，29，5： | 1 |
| 10 | Glued Intrascleral Fixation of Posterior Chamber Intraocular Lens in Children显示文摘 | Dhivya Ashok Kumar Amar Agarwal Dimple Prakash Gaurav Prakash Soosan Jacob Athiya Agarwal | 2012 | American Journal of Ophthalmology2012，，4： | 1 |
| 11 | Estrogen Receptor Beta(ERβ)in endometrial simple hyperplasia and endometrioid carcinoma显示文摘 | Dimple C Radhika S Sujata G | 2008 | Appl Immunohistochem Mol Morphol2008，16，6： | 1 |
| 12 | The impact of Electronic word-of-mouth communication : a literature analysis and integra- tive model 显示文摘 | CHRISTY M K C DIMPLE R T | 2012 | Decision Support Systems2012，54，： | 1 |
| 13 | Global regulator SATB1 recruits β-catenin and regulates TH2 differentiation in Wnt-dependent manner显示文摘 | Dimple Notani Kamalvishnu PG Ranveer SJ | 2010 | PLoS Biology2010，8，1： | 1 |
| 14 | Phosphorylation of SATB1, a Global Gene Regulator, Acts as a Molecular Switch Regulating Its Transcriptional Activity In Vivo显示文摘 | P. Pavan Kumar Prabhat Kumar Purbey Chandan Kumar Sinha Dimple Notani Amita Limaye Ranveer S. Jayani Sanjeev Galande | 2006 | Molecular Cell2006，，2： | 1 |
| 15 | Influence of temperature,pH and yeast on in-field production of ethanolfrom unsterilized sweet sorghum juice显示文摘 | Dimple K K Danielle D B Raymond L H | 2010 | Biomass and Bioenergy2010，34，10： | 1 |
| 16 | Incidence and cause of postpartum urinary stress incontinence显示文摘 | Dimpl TH Hesse U Schuessler B | 1992 | Eur J Obstet Gynecol Reprod Biol1992，43，： | 1 |
| 17 | 9p21 DNA variants associated with coro- nzry mlery disease impair interferon-γ, signalling response 显示文摘 | Olivier H Dimple N Xiaoyuan S | 2011 | Nature2011，470，2： | 1 |
| 18 | Volatilisation and catalytic effects of alkali and alkaline earth metallic species during the pyrolysis and gasification of Victorian brown coal (Ⅳ):Catalytic effects of NaCl and ion-exchangeable Na in coal on char reactivity显示文摘 | Mody Quyn Dimple Wu Hongwei Hayashi JunIchiro | | 0，，05： | 1 |
| 19 | Role of PELPI/MNAR signal- ing in ovarian tumorigenesis 显示文摘 | Dimple C Nair SS Rajhans R | 2008 | Cancer Res2008，68，12： | 1 |
| 20 | Risk Assessment of Drug Interaction Potential and Concomitant Dosing Pattern on Targeted Toxicities in Pediatric Cancer Patients显示文摘 | Jeffrey S. Barrett Dimple Patel Erin Dombrowsky Gaurav Bajaj Jeffrey M. Skolnik | 2013 | The AAPS Journal2013，，3： | 1 |
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