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| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients显示文摘 | Bertrand Baujat Hélène Audry Jean Bourhis Anthony T.C. Chan Haluk Onat Daniel T.T. Chua Dora L.W. Kwong Muhyi al-Sarraf Kwan-Hwa Chi Masato Hareyama Sing F. Leung Kullathorn Thephamongkhol Jean-Pierre Pignon | 2006 | International Journal of Radiation Oncology, Biology, Physics2006，，1： | 2 |
| 3 | B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema显示文摘 | Rana R Vlahakis NE Daniels CE | 2006 | Crit Care Med2006，34，7： | 1 |
| 4 | Traction Behavior of Some Lubricants Used for Rolling Bearings in Spacecraft Applications:Experiments and Thermal Model Based on Primary Laboratory Data显示文摘 | Daniel Ne' lias Eric Legrand Philippe Vergne | 2002 | Transactions of the ASME2002，124，： | 1 |
| 5 | Identification of anovel effector domain of BIN1 for cancer suppression 显示文摘 | Lundgaard GL Daniels NE Pyndiah S | 2011 | J CellBiochem2011，112，10： | 1 |
| 6 | Traction behavior of some lubricants used for rolling bearings in spacecraft applications: experiments and thermal model based on primary laboratory data显示文摘 | Daniel Ne'lias | 2002 | Journal of Tribology2002，124，1： | 1 |
| 7 | B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema显示文摘 | Rana R Vlahakis NE Daniels CE | | 0，，7： | 1 |
| 8 | B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema显示文摘 | Rana R Vlahakis NE Daniels CE | 2006 | Crit Care Med2006，34，7： | 1 |
| 9 | Histologic Findings Predictive of a Diagnosis of De novo Autoimmune Hepatitis After Liver Transplantation in Adults显示文摘 | Mylène Sebagh Marcela Castillo-Rama Daniel Azoulay Audrey Coilly Valérie Delvart Marc-Antoine Allard Alexandre Dos Santos Catherine Johanet Anne-Marie Roque-Afonso Faouzi Saliba Jean-Charles Duclos-Vallée Didier Samuel Anthony Jack Demetris | 2013 | Transplantation Journal2013，，7： | 1 |
| 10 | Identification of a novel effector domain of BIN1 for cancer suppression 显示文摘 | Lundgaard GL Daniels NE Pyndiah S | 2011 | J Cell Biochem2011，112，10： | 1 |
| 11 | Associations between aca- demic stressors, reaction to stress, coping strategies and musculo- skeletal disorders among college students 显示文摘 | Ekpenyong CE Daniel NE Aribe EO | 2013 | Ethiop J Health Sci2013，23，2： | 1 |
| 12 | Peroxisome Proliferator-Activated Receptors and Atherogenesis显示文摘 | Nikolaus Marx Hélène Duez Jean-Charles Fruchart Bart Staels Daniel Kelly | 2004 | Circulation Research: Journal of the American Heart Association2004，，： | 1 |
| 13 | Modeling analysis of the L (-)-carnitine production process by Escherichia coli显示文摘 | Daniel V Guebel Ne'stor V Torres Manuel Ca'novas | 2006 | Process Biochemistry2006，41，： | 1 |
| 14 | Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients显示文摘 | Bertrand Baujat Hélène Audry Jean Bourhis Anthony T.C. Chan Haluk Onat Daniel T.T. Chua Dora L.W. Kwong Muhyi al-Sarraf Kwan-Hwa Chi Masato Hareyama Sing F. Leung Kullathorn Thephamongkhol Jean-Pierre Pignon | 2006 | International Journal of Radiation Oncology Biology Physics2006，，1： | 1 |
| 15 | Interaction of the Rabies Virus P Protein with the LC8 Dynein Light Chain显示文摘 | He'le'ne Raux Anne Flamand and Danielle Blongel | 2000 | Virology2000，74，10： | 1 |
| 16 | Biodiversity and ecosystem services science for a sustainable planet: the DIVERSITAS vision for 2012–20显示文摘 | Anne Larigauderie Anne-Hélène Prieur-Richard Georgina M Mace Mark Lonsdale Harold A Mooney Lijbert Brussaard David Cooper Wolfgang Cramer Peter Daszak Sandra Díaz Anantha Duraiappah Thomas Elmqvist Daniel P Faith Louise E Jackson Cornelia Krug Paul W Lead | 2012 | Current Opinion in Environmental Sustainability2012，，1： | 1 |
| 17 | Combined Liver Resection and Reconstruction of the Supra-Renal Vena Cava: The Paul Brousse Experience显示文摘 | Daniel Azoulay Paola Andreani Umberto Maggi Chadi Salloum Fabiano Perdigao Mylène Sebagh Antoinette Lemoine René Adam Denis Castaing | 2006 | Annals of Surgery2006，，1： | 1 |
| 18 | Correlation of thermal stability of mechanical and optical properties of diamond-like carbon films 显示文摘 | Daniel Franta Vilma Bur? i kov a Ivan Ohl i dal Pavel S?ahel Miloslav ohl i dal David Ne?as | 2007 | Diamond2007，16，： | 1 |
| 19 | Effects of 10 Minutes of Ischemic Preconditioning of the Cadaveric Liver on the Graft?s Preservation and Function: The Ying and the Yang显示文摘 | Daniel Azoulay Massimo Del Gaudio Paola Andreani Philippe Ichai Mylène Sebag René Adam Olivier Scatton Bao Yan Min Valérie Delvard Antoinette Lemoine Henri Bismuth Denis Castaing | 2005 | Annals of Surgery2005，，1： | 1 |
| 20 | Adrenomedullin Blockade Suppresses Growth of Human Hormone–Independent Prostate Tumor Xenograft in Mice显示文摘 | Caroline Berenguer-Daizé Fran?oise Boudouresque Cyrille Bastide Asma Tounsi Zohra Benyahia Julie Acunzo Nadège Dussault Christine Delfino Nathalie Baeza Laurent Daniel Mylène Cayol Dominique Rossi Assou El Battari Denis Bertin Kamel Mabrouk Pierre-Marie M | 2013 | Clinical Cancer Research2013，，22： | 1 |
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