|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Habitual abortions in 678 healthy patients:investigation and pre- vention 显示文摘 | Reznikof- Etievant MF Cayol V Zou GM | 1999 | Hum Reprod1999，14，8： | 1 |
| 2 | Habitual abortions in 678 healthy patients: investigation and prevention显示文摘 | Reznikoff-Etievant MF Cayol V Zou GM Abuaf N Robert A Johanet C Milliez J | 1999 | Human Reproduction1999，14，8： | 1 |
| 3 | Habitual abortions in 678 healthy patients:investigation and prevention显示文摘 | Reznikoff-Etievant MF Cayol V Zou GM | 1999 | Human Reprod1999，14，8： | 1 |
| 4 | Molecular clustering of Pycnoporus strains from various geographic origins and isolation of monokaryotic strains for laccase hyperproduction显示文摘 | Lomascolo A Cayol JL Roche M | 2002 | Mycological Research2002，106，： | 1 |
| 5 | Habitual abortions in 678 healthy patients:investigation and prevention显示文摘 | CAYOL V ZOU GM | 1999 | Hum Reprod1999，14，8： | 1 |
| 6 | Factor V Leiden and G020A prothrombin mutations are risk factors for very early recurrent miscarriage 显示文摘 | Reznikoff MF Cayol V Carbonne B | 2001 | Br J Obstet Gynecol2001，108，： | 1 |
| 7 | Factor V Leiden and G20210A prothrombin mutations are risk factors for very early recurrent miscarriage显示文摘 | Reznikoff-Etievant MF Cayol V Carbonne B | 2001 | Br J Obstet Gynecol2001，108，： | 1 |
| 8 | Factor V Leiden and G 20210A prothrombin mutations are risk factors for very early recur- rent miscarriage显示文摘 | Reznikoff E M F Cayol V Carbonne B | 2001 | Bj og2001，108，12： | 1 |
| 9 | Tindallia texcoconensis sp. nov., a new haloalkaliphilic bacterium isolated from lake Texcoco, Mexico显示文摘 | Didier Alazard Claudia Badillo Marie-Laure Fardeau Jean-Luc Cayol Pierre Thomas Teresa Roldan Jean-Luc Tholozan Bernard Ollivier | 2007 | Extremophiles2007，，1： | 1 |
| 10 | First-line cisplatin,docetaxel,and cetuximab for patients with recurrent or metastatic head and neck cancer:A multicenter cohort study显示文摘BACKGROUND The targeted therapy cetuximab[directed at the epidermal growth factor receptor(EGFR)]in combination with 5-fluorouracil and platinum-based chemotherapy(the EXTREME regimen)has shown substantial efficacy for patients with recurrent or metastatic squamous cell carcinoma of the head and neck(R/M SCCHN).Thus,this scheme has been established as the preferred first-line option for these patients.However,more recently,a new strategy combining platinum,taxanes,and cetuximab(the TPEx regimen)has demonstrated similar efficacy with a more favorable toxicity profile in clinical trials.AIM To evaluate the safety and efficacy of the TPEx scheme as first-line therapy in advanced SCCHN in a multicenter cohort study.METHODS This retrospective multicenter cohort study included patients with histologically confirmed recurrent or metastatic SCCHN treated with first-line TPEx at five medical centers in Argentina between January 1,2017 and April 31,2020.Chemotherapy consisted of four cycles of docetaxel,cisplatin,and cetuximab followed by cetuximab maintenance therapy.Clinical outcomes and toxicity profiles were collected from medical charts.Treatment response was assessed by the investigator in accordance with Response Evaluation Criteria in Solid Tumors(version 1.1).Adverse events were graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events(version 4.0).RESULTS Twenty-four patients were included.The median age at diagnosis was 58 years(range:36-77 years).The majority of patients(83.3%)received at least four chemotherapy cycles in the initial phase.In the included group,the overall response rate was 62.5%,and 3 patients achieved a complete response(12.5%).The median time to response was 2.4 mo[95% confidence interval(CI):1.3-3.5].With a median follow-up of 12.7 mo(95%CI:8.8-16.6),the median progression-free survival(PFS)was 6.9 mo(95%CI:6.5-7.3),and the overall survival rate at 12 mo was 82.4%.Patients with documented tumor response showed a better PFS than those with disease stabilization or progression[8.5 mo(95%CI:5.5-11.5)and 4.5 mo(95%CI:2.5-6.6),respectively;P=0.042].Regarding the safety analysis,two-thirds of patients reported at least one treatment-related adverse event,and 25% presented grade 3 toxicities.Of note,no patient experienced grade 4 adverse events.CONCLUSION TPEx was an adequately tolerated regimen in our population,with low incidence of grade 3-4 adverse events.The median PFS were consistent with those in recent reports of clinical trials evaluating this treatment combination.This regimen may be considered an attractive therapeutic strategy due to its simplified administration,decreased total number of chemotherapy cycles,and treatment tolerability. | Agustin Falco Mariano Leiva Albano Blanco Guido Cefarelli Andres Rodriguez Juan Melo Federico Cayol Manglio Miguel Rizzo Alejandro Sola Hernan Rodriguez Montani Matias Chacon Diego Enrico Federico Waisberg | 2022 | World Journal of Clinical Oncology2022，13，2： | 1 |
| 11 | Effect de quelques substance herbicides communes sur le champignon nematophage 'R350'显示文摘 | CAYOL J C R FRANKOWSKI J P | 1981 | P H M REV Hortic1981，219，： | 1 |
| 12 | Influence of protein intake on whole body and splanchnic leucine kinetics in humans显示文摘 | CAYOL M BO1RIE Y RAMBOURDIN F | 1997 | Am J Physiol1997，272，： | 1 |
| 13 | Influence of protein intake on whole-body and splanchnic leucine kinetics in humans显示文摘 | CAYOL M BOIRIE Y RAMBOURDION F | 1997 | Am J Physiol1997，272，： | 1 |
| 14 | Habitual abortions in 678 healthy patients:investigation and prevention显示文摘 | Reznikoff-Etievant MF Cayol V Zou GM | | 0，，08： | 1 |
| 15 | Medfly areawidesterile insect technique programmes for prevention, suppression oreradication: the importance of mating behavior studies 显示文摘 | HENDRICHS J ROBINSON A S CAYOL J P | 2002 | Florida Entomologist2002，85，： | 1 |
| 16 | Habitual abortions in 678 healthy patients : investigation and prevention 显示文摘 | Reznikoff Etievant M F Cayol V Zou GM | 1999 | Human Reprod1999，14，8： | 1 |
| 17 | Adrenomedullin Blockade Suppresses Growth of Human Hormone–Independent Prostate Tumor Xenograft in Mice显示文摘 | Caroline Berenguer-Daizé Fran?oise Boudouresque Cyrille Bastide Asma Tounsi Zohra Benyahia Julie Acunzo Nadège Dussault Christine Delfino Nathalie Baeza Laurent Daniel Mylène Cayol Dominique Rossi Assou El Battari Denis Bertin Kamel Mabrouk Pierre-Marie M | 2013 | Clinical Cancer Research2013，，22： | 1 |
| 18 | Biological control of grey mould in strawberry fruits by halophilic bacteria 显示文摘 | Essghaier B Fardeau M L Cayol J L | 2009 | Journal of Applied Microbiology2009，106，3： | 1 |
| 19 | Biological Control of Grey Mould in Strawberry Fruits by Halophilic Bacteria显示文摘 | ESSGHAIER B FARDEAU M L CAYOL J L | 2009 | Journal of Applied Microbiology2009，106，： | 1 |
| 20 | Biological control of grey mould in strawberry fruits by halophilic bacteria显示文摘 | Essghaier B Fardeau M L Cayol J L | 2009 | Journal of Applied Microbiology2009，106，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员