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1Diagnosis of biliary strictures after liver transplantation:Which is the best tool?显示文摘AIM: To evaluate the diagnostic value of different indirect methods like biochemical parameters, ultrasound (US) analysis, CT-scan and MRI/MRCP in comparison with endoscopic retrograde cholangiography (ERC), for diagnosis of biliary complications after liver transplantation. METHODS: In 75 patients after liver transplantation, who received ERC due to suspected biliary complications, the result of the cholangiography was compared to the results of indirect imaging methods performed prior to ERC. The cholangiography showed no biliary stenosis (NoST) in 25 patients, AST in 27 and ITBL in 23 patients. RESULTS: Biliary congestion as a result of AST was detected with a sensitivity of 68.4% in US analysis (specificity 91%), of 71% in MRI (specificity 25%) and of 40% in CT (specificity 57.1%). In ITBL, biliary congestion was detected with a sensitivity of 58.8% in the US, 88.9%in MRI and of 83.3% in CT. However, as anastomotic or ischemic stenoses were the underlying cause of biliary congestion, the sensitivity of detection was very low. InMRI detected the dominant stenosis at a correct localization in 22% and CT in 10%, while US failed completely. The biochemical parameters, showed no significant difference in bilirubin (median 5.7; 4,1; 2.5 mg/dL), alkaline phosphatase (median 360; 339; 527 U/L) or gamma glutamyl transferase (median 277; 220; 239 U/L) levels between NoST, AST and ITBL.CONCLUSION: Our data confirm that indirect imaging methods to date cannot replace direct cholangiography for diagnosis of post transplant biliary stenoses. However MRI may have the potential to complement or precede imaging by cholangiography. Optimized MRCP-processing might further improve the diagnostic impact of this method.Thomas Zoepf Evelyn J. Maldonado-Lopez Philip Hilgard Alexander Dech■ne Massimo Malago Christoph E. Broelsch Joerg Schlaak Guido Gerken 2005World Journal of Gastroenterology2005,11,19:32
2Application of high silica zeolite ZSM-5 in a hybrid treatment process based on sequential adsorption and ozonation for VOCs elimination显示文摘In this study,a hydrophobic synthetic zeolite,namely ZSM-5 is chosen as an adsorbent/catalyst for toluene removal.Experimental results showed that toluene adsorption onto ZSM-5 was favourable,following a Langmuir adsorption isotherm model.ZSM-5 zeolite was regenerated using gaseous ozone at low temperature.Adsorbed toluene was oxidised,releasing mainly CO_2 and H_2O.Traces of oxidation by-products such as acetic acid and acetaldehyde were formed and remained adsorbed after the oxidativate regeneration with ozone.After four successive cycles of adsorption/ozonation,the adsorption efficiency was not affected(92%-99%).These results showed that volatile organic compound(VOC)removal by adsorption onto ZSM-5 zeolite followed by ozone regeneration could be used as a promising hybrid process for the control of VOC emissions in terms of efficiency.Hicham Zaitan Marie Hélène Manero Héctor Valdés 2016Journal of Environmental Sciences2016,28,3:23
3Rehabilitation of spinal cord injuries显示文摘Spinal cord injury(SCI) is the injury of the spinal cord from the foramen magnum to the cauda equina whichoccurs as a result of compulsion, incision or contusion. The most common causes of SCI in the world are traffic accidents, gunshot injuries, knife injuries, falls and sports injuries. There is a strong relationship between functional status and whether the injury is complete or not complete, as well as the level of the injury. The results of SCI bring not only damage to independence and physical function, but also include many complications from the injury. Neurogenic bladder and bowel, urinary tract infections, pressure ulcers, orthostatic hypotension, fractures, deep vein thrombosis, spasticity, autonomic dysreflexia, pulmonary and cardiovascular problems, and depressive disorders are frequent complications after SCI. SCI leads to serious disability in the patient resulting in the loss of work, which brings psychosocial and economic problems. The treatment and rehabilitation period is long, expensive and exhausting in SCI. Whether complete or incomplete, SCI rehabilitation is a long process that requires patience and motivation of the patient and relatives. Early rehabilitation is important to prevent joint contractures and the loss of muscle strength, conservation of bone density, and to ensure normal functioning of the respiratory and digestive system. An interdisciplinary approach is essential in rehabilitation in SCI, as in the other types of rehabilitation. The team is led by a physiatrist and consists of the patients' family, physiotherapist, occupational therapist, dietician, psychologist, speech therapist, social worker and other consultant specialists as necessary.Kemal Nas Levent Yazmalar Volkan ?ah Abdulkadir Ayd?n Kadriye ?ne? 2015World Journal of Orthopedics2015,6,1:23
4Brain-lung crosstalk: Implications for neurocritical care patients显示文摘Major pulmonary disorders may occur after brain injuries as ventilator-associated pneumonia, acute respiratory distress syndrome or neurogenic pulmonary edema. They are key points for the management of brain-injured patients because respiratory failure and mechanical ventilation seem to be a risk factor for increased mortality, poor neurological outcome and longer intensive care unit or hospital length of stay. Brain and lung strongly interact via complex pathways from the brain to the lung but also from the lung to the brain. Several hypotheses have been proposed with a particular interest for the recently described 'double hit' model. Ventilator setting in brain-injured patients with lung injuries has been poorly studied and intensivists are often fearful to use some parts of protective ventilation in patients with brain injury. This review aims to describe the epidemiology and pathophysiology of lung injuries in brain-injured patients, but also the impact of different modalities of mechanical ventilation on the brain in the context of acute brain injury.Ségolène Mrozek Jean-Michel Constantin Thomas Geeraerts 2015World Journal of Critical Care Medicine2015,4,3:20
5生物质燃烧颗粒物有机示踪化合物的测定和应用显示文摘使用气相色谱-质谱法对2002年7月-2003年7月的北京市大气粗、细颗粒物样品中的左旋葡聚糖等糖类化合物进行了测定。结果表明,左旋葡聚糖主要存在于细颗粒中,可以作为示踪化合物来研究生物质燃烧现象。生物质燃烧对北京市大气颗粒物有较重要的贡献,对应于12%-40%的PM2.5有机碳和10%-33%的PM10有机碳。北京市在2002年10月和11月受到明显的生物质燃烧的影响,可能由于农田秸杆焚烧和秋季落叶焚烧。2003年5月7日颗粒物样品受到直线距离约为1000 km以外的内蒙古自治区呼伦贝尔市大兴安岭林区森林大火烟雾的影响。生物质燃烧事件具有突发性,可以长距离传输;生物质作为农村生物燃料的使用其燃烧排放具有经常性和持久性的特征。张烃 刘咸德 董树屏 祁辉 Hélène Cachier Magda Claeys 2006岩矿测试2006,25,2:17
6Caveolin-1 gene silencing promotes the activation of PI3K/AKT dependent on Erα36 and the transformation of MCF10A^(CE)显示文摘ERα36,a variant of estrogen receptor-α,acts as a dominant-negative factor in both estrogen-dependent and estrogen-independent transactivation signaling pathways,and is a key factor in the promotion,progression and prognosis of breast cancers.Caveolin-1,a 22-to 24-kD integral membrane protein,may function as a tumor suppressor in inhibiting of many growth-promoting signaling pathways.It was shown that downregulation of Caveolin-1 strengthens the interaction of ERα and Caveolin-1.In conclusion,Caveolin-1 gene silencing activated the PI3K/AKT signaling pathway in an ERα36-dependent way.Our finding may provide a promising therapeutic target of breast cancer.FENG Shuang1,WANG Yang1,WANG Xi1,WANG ZhaoYi3,CUI YuYing1,LIU Jing4,ZHAO ChunHui1,JIN Mei1,2 & ZOU Wei1,2 1 College of Life Science,Liaoning Normal University,Dalian 116029,China 2 Liaoning Key Laboratory of Biotechnology and Molecular Drug R&D,Dalian 116029,China 3 Cancer Center,Creighton University,2500 California Plaza,Omaha,NE 68178,USA 4 First Clinical Hospital of Dalian Medical University,Dalian 116011,China 2010Science China(Life Sciences)2010,53,5:16
7Accuracy and responses of genomic selection on key traits in apple breeding显示文摘The application of genomic selection in fruit tree crops is expected to enhance breeding eficiency by increasing prediction accuracy,increasing selection intensity and decreasing generation interval.The objectives of this study were to assess the accuracy of prediction and selection response in commercial apple breeding programmes for key traits.The training population comprised 977 individuals derived from 20 pedigreed fllsib families.Historic phenotypic data were available on 10 traits related to productivity and fruit external appearance and genotypic data for 7829 SNPs obtained with an llumina 20K SNP array.From these data,a genome-wide prediction model was built and subsequently used to calculate genomic breeding values of five application fllsib families.The application families had genotypes at 364 SNPs from a dedicated 512 SNP array,and these genotypic data were extended to the high-density level by imputation.These five families were phenotyped for 1 year and their phenotypes were compared to the predicted breeding values.Accuracy of genomic prediction across the 10 traits reached a maximum value of 0.5 and had a median value of 0.19.The accuracies were strongly affected by the phenotypic distribution and heritability of traits.In the largest family,significant selection response was observed for traits with high heritability and symmetric phenotypic distribution.Traits that showed non-significant response often had reduced and skewed phenotypic variation or low heritability.Among the five application families the accuracies were uncorrelated to the degree of relatedness to the training population.The results underline the potential of genomic prediction to accelerate breeding progress in outbred fruit tree crops that still need to overcome long generation intervals and extensive phenotyping costs.Hélène Muranty Michela Troggio Inès Ben Sadok Mehdi Al Rifaï Annemarie Auwerkerken Elisa Banchi Riccardo Velasco Piergiorgio Stevanato W.Eric van de Weg Mario Di Guardo Satish Kumar François Laurens Marco C.A.M.Bink 2015Horticulture Research2015,2,1:14
8Contamination,Fractionation and Availability of Metals in Urban Soils in the Vicinity of Former Lead and Zinc Smelters,France显示文摘smelters in Northern France were studied by analysing the chemical forms of these metals and evaluating their phytoavailability. These metals were determined using flame or electrothermal absorption atomic spectrometry (FAAS or ETAAS), depending on their concentration levels. After optimisation of the ETAAS method, characteristic mass of In in water and aqua regia were 9.9 and 18 pg, respectively, showing the high sensitivity of the analytical Soil contamination by metals from anthropogenic activities (e.g., mining and smelting) is a major concern for the environment and human health. Environmental availability of cadmium (Cd), lead (Pb), zinc (Zn), copper (Cu), and indium (In) in 27 urban soils located around two former Pb and Zn smelters in Northern France were studied by analysing the chemical forms of these metals and evaluating their phytoavailability. These metals were determined using flame or electrothermal absorption atomic spectrometry (FAAS or ETAAS), depending on their concentration levels. After optimisation of the ETAAS method, characteristic mass of In in water and aqua regia were 9.9 and 18 pg, respectively, showing the high sensitivity of the analytical procedure. Metal partitioning was conducted using a four-step sequential extraction procedure. The results showed that Cd and Zn were mainly in the acid-extractable and reducible forms in the urban soils studied. In contrast, Pb and In were largely in the reducible fraction. However, in some samples, the amount of In extracted in the residual or exchangeable fraction was higher than that in the reducible fraction. Copper was mainly found in the reducible and residual fractions. A pot experiment was conducted in a glasshouse with seven soils (six contaminated and one uncontaminated) and two plant species, ryegrass and lettuce. The results showed transfer of metals from the contaminated soils to the shoots of ryegrass and the edible part of lettuce. The metal bioconcentration factor was in the order of Cd Cu > In > Zn Pb for lettuce leaves, whereas for ryegrass shoots, three orders were found, Cd > Zn > Cu In > Pb, Cd ≥ In > Zn > Cu Pb, and Zn > Cd > Cu > In > Pb, depending on the physico-chemical properties of the soils, such as pH, cation exchange capacity, carbonates, and organic matter. It was established that the metal toxicity was related to the contamination levels and the physico-chemical properties, including pH, organic matter, and in a lesser extent, Ca, Mg, and phosphorus contents, of the soils. However, it was shown that lettuce could grow on soils having high Cd and CaCO_3 contents. Cadmium was one of the most available metals while Pb was always the least available in the soils studied.C.WATERLOT G.BIDAR A.PELFRNE H.ROUSSEL H.FOURRIER F.DOUAY 2013Pedosphere2013,23,2:12
9An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond.Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg 2018Horticulture Research2018,5,1:10
10H2O2-Activated Up-Regulation of Glutathione in Arabidopsis Involves Induction of Genes Encoding Enzymes Involved in Cysteine Synthesis in the Chloroplast显示文摘谷胱甘肽在对 H2O2 的反应是在细胞的氧化还原作用动态平衡并且,因此的一个关键播放器,但是调整激活氧化的谷胱甘肽合成的因素仍然是不清楚的。我们在有条件的 Arabidopsis 过氧化氢酶缺乏的异种(cat2 ) 调查了导致 H2O2 的谷胱甘肽合成。植物为 5 在提高的 CO2 从种子被种 ? 星期,然后处于短天或长天的条件转了到空气。处于任何条件在提高的 CO2 或野类型的植物比作 cat2,到在两个光周期的空气的 cat2 的转移在小时以内引起了叶谷胱甘肽水池的可测量的氧化。氧化在随后的天继续并且被谷胱甘肽的累积伴随。这效果在在短天内转移到空气的 cat2 是更强壮的,并且没被连接到可引出的活动或涉及谷胱甘肽合成的承诺的小径的抄本编码酶的可估计的增加。相反,它被丝氨酸, O-acetylserine,和半胱氨酸的增加伴随。在代谢物的这些变化被编码腺苷 phosphosulfate reductase (4 月) 的基因的正式就职伴随,特别地, APR3,以及编码 chloroplastic 的特定的丝氨酸 acetyltransferase 基因(SAT2.1 ) 坐了。标记这些基因的正式就职仅仅在处于短天的条件转移到空气的 cat2 被观察,在半胱氨酸和谷胱甘肽累积是很戏剧的的地方。不同于另外的容纳的基因,它在 cat2 显示出可以忽略的正式就职,相对许多 4 月和 SAT2.1 抄本密切为 H2O2 发信号与标记抄本被相关。一起,数据在谷胱甘肽合成的导致氧化剂的起来规定加重半胱氨酸合成的重要性并且建议叶绿体在这些情形下面做重要贡献到半胱氨酸生产。Guillaume Queval Dorothée Thominet Hélène Vanacker Myroslawa Miginiac-Maslow Bertrand Gakière Graham Noctor 2009Molecular Plant2009,2,2:10
11Quasispecies evolution in NS5A region of hepatitis C virus genotype 1b during interferon or combined interferon-ribavirin therapy显示文摘AIM: To evaluate the implication of substitutions in the hepatitis C virus (HCV) non-structural 5A (NS5A) protein in the resistance of HCV during mono-interferon (IFN) or combined IFN-ribavirin (IFN-R) therapy. Although NS5A has been reported to interact with the HCV RNA- dependent RNA polymerase, NS5B, as well as with many cellular proteins, the function of NS5A in the life cycle of HCV remains unclear. METHODS: HCV quasispecies were studied by clon- ing and sequencing of sequential isolates from patients infected by HCV genotype 1b. Patients were treated by IFN-α2b for 3 mo followed by IFN-α2b alone or com- bined IFN-R therapy for 9 additional months. Patients were categorized intro two groups based on their re- sponse to the treatments: 7 with sustained virological re- sponse (SVR) (quasispecies = 150) and 3 non-respond- ers (NR) to IFN-R (quasispecies = 106). RESULTS: Prior to treatment, SVR patients displayed a lower complexity of quasispecies than NR patients. Most patients had a decrease in the complexity of quasispe- cies during therapy. Analysis of amino acids substitu- tions showed that the degree of the complexity of the interferon sensitivity-determining region (ISDR) and the V3 domain of NS5A protein was able to discriminate thetwo groups of patients. Moreover, SVR patients displayed more variability in the NS5A region than NR patients. CONCLUSION: These results suggest that detailed mo- lecular analysis of the NS5A region may be important for understanding its function in IFN response during HCV 1b infection.Pascal Veillon Christopher Payan Hélène Le Guillou-Guillemette Catherine Gaudy Franoise Lunel 2007World Journal of Gastroenterology2007,13,8:9
12局部进展期直肠癌:综合化疗的新辅助放疗后的MR影像再分期。第二部分:预测受累淋巴结的标准是什么?显示文摘目的前瞻性明确直肠癌病人综合放化疗后超微超顺磁氧化铁粒子(USPIO)增强MR成像淋巴结再分期预测标准的诊断价值。材料与方法本研究经过机构审查委员会批准,39例直肠癌病人(男24例,女15例,平均年龄64岁)签署了知情同意书,行USPIO增强2DT2加权快速自旋回波、3D T1加权梯度回波和3DT2*WMR扫描,用于分期诊断。M.Lahaye G.Beets S.Engelen A.Kessels A.de Brune H.Kwee 高莉 2009国际医学放射学杂志2009,32,5:9
13A low frequency piezoelectric power harvester using a spiral-shaped bimorph显示文摘We propose a spiral-shaped piezoelectric bimorph power harvester operating with coupled flexural and extensional vibration modes for applications to low frequency energy sources. A theoretical analysis is performed and the computational results show that the spiral structure has relatively low operating frequency compared to beam power harvesters of the same size. It is found that to optimize the performance of a piezoelectric spiral-shaped harvester careful design is needed.HU Yuantai1,2,HU Hongping2 & YANG Jiashi3 1. Institute of Mechanics and Sensing Technology,Central South University,Changsha 410083,China 2. Department of Mechanics,Huazhong University of Science and Technology,Wuhan 430074,China 3. Department of Engineering Mechanics,University of Nebraska,Lincoln,NE 68588-0526,USA 2006Science China(Physics,Mechanics & Astronomy)2006,49,6:9
14Isolation and characterization of facultative mixotrophic ammonia-oxidizing bacteria from constructed wetlands显示文摘Autotrophic ammonia-oxidizing bacteria (AOB) have been widely studied in constructed wetlands systems,while mixotrophic AOB have been less thoroughly examined.Heterotrophic bacteria were isolated from wastewater and rhizospheres of macrophytes of constructed wetlands,and then cultivated in a mixotrophic medium containing ammonium and acetic acid.A molecular characterization was accomplished using ITS-PCR amplification,and phylogenetic analysis based on 16S rRNA gene sequences.Results showed the presence of 35 bacteria,among 400 initially heterotrophic isolates,that were able to remove ammonia.These 35 isolates were classified into 10 genetically different groups based on ITS pattern.Then,a collection of 10 isolates were selected because of their relatively high ammonia removal efficiencies (ARE 80%) and their phylogenetic diversity.In conditions of mixotrophy,these strains were shown to be able to grow (increase of optical density OD 660 during incubation with assimilation of nitrogen into cellular biomass) and to oxidize ammonia (important ammonia oxidation efficiencies,AOE between 79% and 87%).Among these facultative mixotrophic AOB,four isolates were genetically related to Firmicutes (Bacillus and Exiguobacterium),three isolates were affiliated to Actinobacteria (Arthrobacter) and three other isolates were associated with Proteobacteria (Pseudomonas,Ochrobactrum and Bordetella).Soulwène Kouki Neila Saidi Fadhel M'hiri Houda Nasr Hanène Cherif Hadda Ouzari Abdennaceur Hassen 2011Journal of Environmental Sciences2011,23,10:9
15Adenoviral-mediated Hath1-EGFP gene transfer into guinea pig cochlea through intact round window membrane显示文摘Objective To study expression of adenoviral-mediated Hath1-EGFP gene in the guinea pig cochlea after transfer through intact round window membrane(RWM), and to assess its effects on hearing. Methods Twenty adult guinea pigs were used, of which: 12 were surgically inoculated with Ad-Hath1-EGFP in the bony groove of round window niche, and 8 with artificial perilymph. Auditory brainstem response(ABR) thresholds were determined in all animals before and 5 days after surgery. On post-surgery day 5 and day 14, animals were sacrificed and whole mounts of cochlea and frozen sections were examined. Results ABR tests showed no significant change of hearing after the surgery. Strong fluorescence staining in the cochleae was seen in Ad-Hath1-EGFP groups. The highest levels of gene expression were seen in the post-surgery day 5 group with little decrease on post-surgery day 14.The contralateral cochlea and those in the control groups were free of fluorescence staining. Conclusion The transgenic Hath1-EGFP can be effectively delivered into the inner ear through intact RWM, in an atraumatic manner.CHEN Wei1☆, HU Yin-yan1☆, YANG Shi-ming1*, GUO Wei1, SUN Jian-he1, HAN Dong-yi1, ZHAI Suo-qiang1, YANG Wei-yan1, David Z.Z.He2 1. Neurologic Biological centre, Institute of Otolaryngology, Department of Otorhinolaryngology-Head & Neck Surgery, Chinese PLA General Hospital, Beijing 100853, China 2. Department of Biomedical Sciences, Creighton University, 2500 California Plaza, Omaha, NE 68175, USA 2008Journal of Otology2008,3,1:7
16Insect immune resistance to parasitoids显示文摘昆虫主人 -- parasitoid 相互作用包含复杂生理、生物化学、基因的相互作用。对 endoparasitoids,免疫者能干的主人开始血快速破坏入侵者并且包围的调停房间的反应他们在 multilayered 以黑色素为特征的囊。在过去的十年期间,可观的进步在识别一些主人反应的批评部件被取得了,主要因为有效分子的工具的使用。这评论检验一些果蝇的天生的免疫反应的部件,为学习非自我识别担任了一个特别好的试验性的模型的一只昆虫处理并且有免疫力的房间发信号机制。在这评论考虑的话题包括血球, melanogenesis 和联系细胞毒素的分子的造血作用,增长和粘附,并且 host-parasitoid 相互作用的基因方面。Yves Carton Marylène Poirié Anthony J. Nappi 2008Insect Science2008,15,1:7
17酸洗和固溶处理对不锈钢抗点蚀性能的影响显示文摘研究了酸洗和固溶处理对 8种不锈钢钢筋电阻对焊接头抗点蚀能力的影响。研究发现 ,酸洗和固溶处理都能有效地改善和恢复不锈钢电阻对焊接头的抗点蚀性能。对于普通双相钢 ,固溶处理比酸洗能更有效地改善接头的抗点蚀性能 ,并无晶粒粗化现象 ;对于奥氏体钢和超级奥氏体钢 ,固溶处理的效果不及酸洗 ,且会引起母材晶粒粗化。对含Mo含N较高钢种的对焊接头 ,两者的效果更佳 ,尤其是两者综合处理后的接头 ,其临界点蚀温度CPT甚至高于对应母材经酸洗以后的CPT。文章对比分析了母材和固溶处理前后接头的显微组织 ,讨论了引起上述抗点蚀性能变化的原因。文章还探讨了酸洗和Mo、N元素可以改善不锈钢抗点蚀性能的机理。胡礼木 NE Hannerz 2000焊接学报2000,21,1:6
18Applying FAIR Principles to Plant Phenotypic Data Management in GnpIS显示文摘GnpIS is a data repository for plant phenomics that stores whole field and greenhouse experimental data including environment measures.It allows long-term access to datasets following the FAIR principles:Findable,Accessible,Interoperable,and Reusable,by using a flexible and original approach.It is based on a generic and ontology driven data model and an innovative software architecture that uncouples data integration,storage,and querying.It takes advantage of international standards including the Crop Ontology,MIAPPE,and the Breeding API.GnpIS allows handling data for a wide range of species and experiment types,including multiannual perennial plants experimental network or annual plant trials with either raw data,i.e.,direct measures,or computed traits.It also ensures the integration and the interoperability among phenotyping datasets and with genotyping data.This is achieved through a careful curation and annotation of the key resources conducted in close collaboration with the communities providing data.Our repository follows the Open Science data publication principles by ensuring citability of each dataset.Finally,GnpIS compliance with international standards enables its interoperability with other data repositories hence allowing data links between phenotype and other data types.GnpIS can therefore contribute to emerging international federations of information systems.C.Pommier C.Michotey G.Cornut P.Roumet E.Duchêne R.Flores A.Lebreton M.Alaux S.Durand E.Kimmel T.Letellier G.Merceron M.Laine C.Guerche M.Loaec D.Steinbach M.A.Laporte E.Arnaud H.Quesneville A.F.Adam-Blondon 2019Plant Phenomics2019,1,1:6
19纳米技术:基于相关指标及统计数据的述评(Ⅱ)显示文摘3 纳米技术应用领域及机构分析3.1概述研究及分析人员认为,纳米技术可能发展为下一代通用技术,这意味着纳米技术将很可能迅速发展成为在各应用领域及产业广泛应用的技术㈣。其主要依据是纳米技术使得在基本原子和分子水平更深入地认识和控制物质成为可能,从而有助于改进几乎所有产业的制造工艺。Christopher Palmberg Hélène Dernis Claire Miguet 张树良 2011科技导报2011,29,23:5
20黑龙江东部双鸭山、集贤煤田中生代含煤地层研究显示文摘本文系统地讨论了黑龙江双鸭山、集贤两煤田的中生代含煤地层序列,综合各门类化石研究结果,认为海相的绥滨组和东荣组属晚侏罗世卡洛夫晚期至伏尔加期,非海相的城子河组和穆棱组属早白垩世尼坎期。文内提供11条详细的钻探剖面的生物地层资料。110th Exploring Team, NE China-Nei Monggol Coal Corporation, Shuangyashan 155100, Heilongjiang 1992古生物学报1992,31,2:5
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