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| 1 | Crucial steps in the natural history of inflammatory bowel disease显示文摘Inflammatory bowel diseases(IBD),including ulcerative colitis(UC) and Crohn's disease(CD),are chronic,progressive and disabling disorders.Over the last few decades,new therapeutic approaches have been introduced which have led not only to a reduction in the mortality rate but also offered the possibility of a favorable modification in the natural history of IBD.The identification of clinical,genetic and serological prognostic factors has permitted a better stratification of the disease,thus allowing the opportunity to indicate the most appropriate therapy.Early treatment with immunosuppressive drugs and biologics has offered the opportunity to change,at least in the short term,the course of the disease by reducing,in a subset of patients with IBD,hospitalization and the need for surgery.In this review,the crucial steps in the natural history of both UC and CD will be discussed,as well as the factors that may change their clinical course.The methodological requirements for high quality studies on the course and prognosis of IBD,the true impact of environmental and dietary factors on the clinical course of IBD,the clinical,serological and genetic predictors of the IBD course(in particular,which of these are rel-evant and appropriate for use in clinical practice),the impact of the various forms of medical treatment on the IBD complication rate,the role of surgery for IBD in the biologic era,the true magnitude of risk of colorectal cancer associated with IBD,as well as the mortality rate related to IBD will be stressed;all topics that are extensively discussed in separate reviews included in this issue of World Journal of Gastroenterology. | Giovanni Latella Claudio Papi | 2012 | World Journal of Gastroenterology2012，18，29： | 7 |
| 2 | Mucosal healing in inflammatory bowel disease: treatment efficacy and predictive factors显示文摘 | Claudio Papi Federica Fascì Spurio Francesca Rogai Alessia Settesoldi Giovanna Margagnoni Vito Annese | 2013 | Digestive and Liver Disease2013，，： | 2 |
| 3 | Methotrexate-induced pneumonitis in a patient with Crohn’s disease显示文摘 | Giovanna Margagnoni Valeria Papi Annalisa Aratari Luca Triolo Claudio Papi | 2009 | Journal of Crohn’s and Colitis2009，，2： | 2 |
| 4 | Slug/β-Catenin–Dependent Proinflammatory Phenotype in Hypoxic Breast Cancer Stem Cells显示文摘 | Gianluca Storci Sara Bertoni Sabrina De Carolis Alessio Papi Marina Nati Claudio Ceccarelli Chiara Pirazzini Paolo Garagnani Alberto Ferrarini Genny Buson Massimo Delledonne Michelangelo Fiorentino Elisa Capizzi Elisa Gruppioni Mario Taffurelli Donatella | 2013 | The American Journal of Pathology2013，，5： | 1 |
| 5 | Infliximab for Severe Recurrent Crohn’s Disease Presenting With Massive Gastrointestinal Hemorrhage显示文摘 | Claudio Papi Loredana Gili Maurizio Tarquini Giorgio Antonelli Lucio Capurso | 2003 | Journal of Clinical Gastroenterology2003，，3： | 1 |
| 6 | Plasma s RAGE and N ‐(carboxymethyl) lysine in patients with CHF and/or COPD显示文摘 | Piera Boschetto Ilaria Campo Mariarita Stendardo Enrico Casimirri Carmine Tinelli Marina Gorrini Claudio Ceconi Alessandro Fucili Alfredo Potena Alberto Papi Licia Ballerin Leonardo Fabbri Maurizio Luisetti | 2013 | Eur J Clin Invest2013，，6： | 1 |
| 7 | Regional variations in the use of complementary and alternative medicines (CAM) for inflammatory bowel disease patients in Italy: An IG-IBD study显示文摘 | Perla Bertomoro Sara Renna Mario Cottone Gabriele Riegler Fabrizio Bossa Licio Giglio Luca Pastorelli Claudio Papi Fabiana Castiglione Erika Angelucci Roberta Pica Maria Carla Di Paolo Renata D’Incà | 2009 | Journal of Crohn’s and Colitis2009，，3： | 1 |
| 8 | Controlling DNA Bundle Size and Spatial Arrangement in Selfassembled Arrays on Superhydrophobic Surface显示文摘The use of superhydrophobic surfaces(SHSs) is now emerging as an attractive platform for the realization of one-dimensional(1D) nanostructures with potential applications in many nanotechnological and biotechnological fields.To this purpose, a strict control of the nanostructures size and their spatial arrangement is highly required. However, these parameters may be strongly dependent on the complex evaporation dynamics of the sessile droplet on the SHS. In this work, we investigated the effect of the evaporation dynamics on the size and the spatial arrangement of self-assembled 1D DNA bundles. Our results reveal that different arrangements and bundle size distributions may occur depending on droplet evaporation stage. These results contribute to elucidate the formation mechanism of 1D nanostructures on SHSs. | Gabriele Ciasca Massimiliano Papi Valentina Palmieri Michela Chiarpotto Simone Di Claudio Adele De Ninno Ennio Giovine Gaetano Campi Annamaria Gerardino Luca Businaro Marco De Spirito | 2015 | Nano-Micro Letters2015，7，2： | 0 |
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