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| 1 | The role of structural inheritance in continental break-up and exhumation of Alpine Tethyan mantle(Canavese Zone,Western Alps)显示文摘The Canavese Zone(CZ)in the Western Alps represents the remnant of the distal passive margin of the Adria microplate,which was stretched and thinned during the Jurassic opening of the Alpine Tethys.Through detailed geological mapping,stratigraphic and structural analyses,we document that the continental break-up of Pangea and tectonic dismemberment of the Adria distal margin,up to mantle rocks exhumation and oceanization,did not simply result from the syn-rift Jurassic extension but was strongly favored by older structu ral inheritances(the Proto-Canavese Shear Zone),which controlled earlier lithospheric weakness.Our findings allowed to redefine in detail(i)the tectono-stratigraphic setting of the Variscan metamorphic basement and the Late Carbonife rous to Early Cretaceous CZ succession,(ii)the role played by inherited Late Carboniferous to Early Triassic structures and(iii)the significance of the CZ in the geodynamic evolution of the Alpine Tethys.The large amount of extensional displacement and crustal thinning occurred during different pulses of Late Carbonife rous-Early Triassic strike-slip tectonics is wellconsistent with the role played by long-lived regional-scale wrench faults(e.g.,the East-Variscan Shear Zone),suggesting a re-discussion of models of mantle exhumation driven by low-angle detachment faults as unique efficient mechanism in stretching and thinning continental crust. | Andrea Festa Gianni Balestro Alessandro Borghi Sara De Caroli Andrea Succo | 2020 | Geoscience Frontiers2020，11，1： | 4 |
| 2 | Could sport be part of pediatric obesity prevention and treatment? Expert conclusions from the 28th European Childhood Obesity Group Congress显示文摘The prevalence of pediatric obesity continues to increase worldwide,bringing with it various metabolic,functional,social,and psychological complications.1 Both the prevention and treatment of childhood obesity must be based on multidisciplinary approaches combining nutrition,physical activity(PA),and psychological support.2 As an essential element of these multicomponent strategies,regular physical activity has been acknowledged as having beneficial effects on children's and adolescents,body composition,physical fitness,and metabolic profile,as well as on their health-related quality of life,social and psychological health,and academic achievement.3,4 Given that only a relatively small proportion of children and adolescents meet the public health recommendations for PA,5 and given that weight loss exercise-based interventions suffer from a high attrition rate,there is a clear need for appropriate PAs. | Susanne Ring-Dimitriou Peter Krustrup Manuel J Coelho-E-Silva Jorge Mota Andera Seabra Carla Rego Artur Mazur Elpis Vlachopapadopoulou Margerita Caroli Marie-Laure Frelut Eva Erhardt Anders Forslund Ema Boyland Daniel Weghuber David Thivel | 2019 | Journal of Sport and Health Science2019，8，4： | 3 |
| 3 | Depletion of calcitonin gene-related peptide in peprivascular never during acute phase of posthemorrhagic vasospasm in the rabbit 显示文摘 | Arienta C Balli S Caroli M | 1991 | Brain Res Bull1991，27，： | 2 |
| 4 | Potential therapeutic role of microRNAs in ischemic heart disease显示文摘 | Annalisa Caroli Maria Teresa Cardillo Roberto Galea Luigi M. Biasucci | 2013 | Journal of Cardiology2013，，： | 2 |
| 5 | Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells显示文摘Background: Innate immune responses induced by in vitro stimulation of primary mammary epithelial cells(MEC) using Gram-negative lipopolysaccharide(LPS) and Gram-positive lipoteichoic acid(LTA) bacterial cell wall components are well-characterized in bovine species. The objective of the current study was to characterize the downstream regulation of the inflammatory response induced by Toll-like receptors in primary goat MEC(pgMEC). We performed quantitative real-time RT-PCR(qPCR) to measure mRNA levels of 9 genes involved in transcriptional regulation or antibacterial activity: Toll-like receptor 2(TLR2), Toll-like receptor 4(TLR4), prostaglandin-endoperoxide synthase 2(PTGS2), interferon induced protein with tetratricopeptide repeats 3(IFIT3), interferon regulatory factor 3(IRF3), myeloid differentiation primary response 88(MYD88), nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(NFKB1), Toll interacting protein(TOLLIP), and lactoferrin(LTF). Furthermore,we analyzed 7 cytokines involved in Toll-like receptor signaling pathways: C-C motif chemokine ligand 2(CCL2), C-C motif chemokine ligand 5(CCL5), C-X-C motif chemokine ligand 6(CXCL6), interleukin 8(CXCL8), interleukin 1 beta(IL1 B), interleukin 6(IL6), and tumor necrosis factor alpha(TNF).Results: Stimulation of pgMEC with LPS for 3 h led to an increase in expression of CCL2, CXCL6, IL6, CXCL8,PTGS2, IFIT3, MYD88, NFKB1, and TLR4(P < 0.05). Except for IL6, and PTGS2, the same genes had greater expression than controls at 6 h post-LPS(P < 0.05). Expression of CCL5, PTGS2, IFIT3, NFKB1, TLR4, and TOLLIP was greater than controls after 3 h of incubation with LTA(P < 0.05). Compared to controls, stimulation with LTA for 6 h led to greater expression of PTGS2, IFIT3, NFKB1, and TOLLIP(P < 0.05) whereas the expression of CXCL6, CXCL8, and TLR4 was lower(P < 0.05). At 3 h incubation with both toxins compared to controls a greater expression(P < 0.05) of CCL2, CCL5, CXCL6, CXCL8, IL6, PTGS2, IFIT3, IRF3, MYD88, and NFKB1 was detected. After 6 h of incubation with both toxins, the expression of CCL2, CXCL6, IFIT3, MYD88, NFKB1, and TLR4 was higher than the controls(P < 0.05).Conclusions: Data indicate that in the goat MEC, LTA induces a weaker inflammatory response than LPS.This may be related to the observation that gram-positive bacteria cause chronic mastitis more often than gram-negative infections. | Omar Bulgari Xianwen Dong Alfred L.Roca1 Anna M. Caroli Juan J. Loor | 2017 | Journal of Animal Science and Biotechnology2017，8，4： | 2 |
| 6 | Element Speciation: Challenges and Prospects显示文摘 | S. Caroli | 1995 | Microchemical Journal1995，，1： | 2 |
| 7 | Meningiomas infiltrating the superior sagittal sinus:surgical considerations of 328 cases显示文摘 | Caroli E Orlando ER Mastronardi L | 2006 | Neurosurg Rev2006，29，3： | 1 |
| 8 | Anterior cervical fusion with interbody titanium cage containing surgical bone site graft:our institution's experience in 103consecutive cases degenerative spondylosis 显示文摘 | Caroli E Oriando ER Dandrea G | 2007 | J Spinal Disord Tech2007，20，： | 1 |
| 9 | Limbal anaesthesia versus topical anaesthesia for clear corneal phacoemulsification 显示文摘 | Cagini C De Carolis A Fiore T | 2006 | Acta Ophthalmol Seand2006，84，1： | 1 |
| 10 | Meningiomas infiltrating the superior sagittal sinus: surgical considera- tions of 328 cases 显示文摘 | Caroli E Orlando ER Mastronardi L | 2006 | Neurosurg Rev2006，29，3： | 1 |
| 11 | MALDI-TOF mass spectrometry in the clinical mycology laboratory: identification of fungi and beyond 显示文摘 | Posteraro B1 De Carolis E Vella A et ol | 2013 | Expert Rev Proteomics2013，10，2： | 1 |
| 12 | Species identification of Aspergillus, Fusarium and Mucorales with direct surface analysis by matrix-assisted laser desorption ionization time-of-flight mass spectrometry显示文摘 | De Carolis E Posteraro B Lass-Florl C | 2012 | Clin Microbiol Infect2012，18，5： | 1 |
| 13 | Comparative activity of quinolones against 326 clinical isolates of stenotrophomonas maltophilia显示文摘 | Weiss K Restieri C de Carolis E | 2000 | J Antimierob Chemother2000，45，3： | 1 |
| 14 | In vitro susceptibility of Candida species to fiveantifungal agents in a German universityhospital assessed by the reference brothmicrodilution method and Etest显示文摘 | DE Carolis E Sanguinetti M Florio A R | 2010 | JChemother2010，22，1： | 1 |
| 15 | Transient hypohidrosis induced by topiramate显示文摘 | De Carolis P Magnifico F Pierangeli G | 2003 | Epilepsia2003，44，： | 1 |
| 16 | Glutathione: A key player in autoimmunity显示文摘 | Carlo Perricone Caterina De Carolis Roberto Perricone | 2009 | Autoimmunity Reviews2009，，8： | 1 |
| 17 | HLA-A2 restricted,melanocytespecific CD8 (+) T lymphocytes detected in vitiligo patients are related to disease activity and are predominantly directed against MelanA/MART1显示文摘 | Lang KS Caroli CC Muhm A | | 0，，： | 1 |
| 18 | Spinal en plaque meningiomas:A contemporary experience显示文摘 | Caroli E Acqui M Roperto R | 2004 | Neurosurgery2004，55，6： | 1 |
| 19 | Ine- quality and economic growth: the perspective of the new growth theories显示文摘 | Aghion P Caroli E Garcia - Penalosa C | 1999 | Journal of Economic literature1999，，： | 1 |
| 20 | GM-CSF and pregnancy:evidence of significantly reduced blood concentrations in immunoglobulin treatment显示文摘 | Perricone R De Carolis C Giacomelli R | 2003 | Am J Reprod Immunol2003，50，3： | 1 |
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