|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Immune response to hepatitis B virus vaccine in celiac subjects at diagnosis显示文摘AIM To evaluate hepatitis B virus(HBV) vaccine response and correlation with human leukocyte antigens(HLA) and/or gluten intake in celiac patients at diagnosis.METHODS Fifty-one patients affected by celiac disease, diagnosed at the Department of Pediatrics of the University of Catania(Italy), were recruited. All patients were tested at admission for immunization against HBV, according to findings from analysis of quantitative HBV surface antibody(anti-HBs). The anti-HBs titer was measured by enzyme-linked immunosorbent assay. Following the international standards, subjects with antibody titer < 10 IU/L were defined as non-responders. The prevalence of responders and non-responders among celiac subjects and the distribution of immunization for age were examined. In addition, the prevalence of responders and non-responders was assessed for correlation to HLA and clinical features at diagnosis of celiac disease.RESULTS The entire study population was divided into three groups according to age: 24 patients aged between 0to 5.5 years(48.9%, group A); 16 aged between 5.5 and 9.5 years(30.61%, group B); 9 aged between 9.5 and 17 years(18.75%, group C). Comparison of the percentage of responders and non-responders between the youngest and the oldest age group showed no significant difference between the two groups(P > 0.05). With regard to the HLA haplotype, comparison of the distribution of vaccination response showed no statistically significant difference between the different genotypes(homozygosity for the HLADQ2 haplotype compared with HLADQ2/DQ8 heterozygosity or other haplotypes; P > 0.05). Moreover, distribution of the responders according to clinical features of celiac disease showed no statistically significant differences(P > 0.05).CONCLUSION This prospective study confirmed the lower percentage of response to HBV vaccine in celiac subjects. However, the underlying mechanism remains unclear and further studies are needed. | Martina Filippelli Maria Teresa Garozzo Antonino Capizzi Massimo Spina Sara Manti Lucia Tardino Carmelo Salpietro Salvatore Leonardi | 2016 | World Journal of Hepatology2016，8，26： | 5 |
| 2 | Cutaneous manifestations of hepatitis C in the era of new antiviral agents显示文摘The association of chronic hepatitis C virus(HCV) infection with a wide spectrum of cutaneous manifestations has been widely reported in the literature, with varying strength of epidemiological association. Skin diseases which are certainly related with chronic HCV infection due to a strong epidemiological and pathogenetic association are mixed cryoglobulinemia, lichen planus and porphyria cutanea tarda. Chronic pruritus and necrolytic acral erythema are conditions that may share a possible association with HCV infection, while several immune-mediated inflammatory skin conditions, such as psoriasis, chronic urticaria and vitiligo, have been only anecdotally reported in the setting of chronic HCV infection. Traditional interferonbased treatment regimens for HCV infection are associated with substantial toxicity and a high-risk of immune-related adverse events, while the advent of new direct-acting antivirals with sustained virological response and improved tolerability will open the door for all-oral, interferon-free regimens. In the new era of these direct acting antivirals there will be hopefully a renewed interest in extra-hepatic manifestations of HCV infection. The aim of the present paper is to review the main cutaneous HCV-related disorders- mixed cryoglobulinemia, lichen planus, porphyria cutanea tarda and chronic pruritus- and to discuss the potential impact of new antiviral treatments on the course of these extrahepatic manifestations of chronic HCV infection. | Simone Garcovich Matteo Garcovich Rodolfo Capizzi Antonio Gasbarrini Maria Assunta Zocco | 2015 | World Journal of Hepatology2015，7，27： | 5 |
| 3 | An Adaptive Exponentially Weighted Moving Average Control Chart显示文摘 | Giovanna Capizzi Guido Masarotto | 2003 | Technometrics2003，，3： | 3 |
| 4 | The preclinical basis broad-spectrum selective cytoprotection of normal tissues from cytotoxic therapies by amifostine显示文摘 | CAPIZZI R L | 1999 | Semin Oncol1999，26，27： | 1 |
| 5 | The preclinical basis for broad -spectrum se-lective cytotoxic therapies by amifostine显示文摘 | Capizzi RL | 1999 | Semin Oncol1999，26，7： | 1 |
| 6 | Treatment of poor risk acute leukemia with sequential high-dose ARA-C and asparaginase显示文摘 | Capizzi RL Poole M Cooper MR | 1984 | Blood1984，63，3： | 1 |
| 7 | Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease显示文摘 | Ryu JH Myers JL Capizzi SA | 2005 | Chest2005，127，1： | 1 |
| 8 | A multilayer perceptron neural model for the differentiation of laplacian 3-D finite-element solutions 显示文摘 | Capizzi G Coco S Laudani A | 2003 | IEEE Transactions on Magnetics2003，39，3： | 1 |
| 9 | Advances in Microgeophysics for Engineering and Cultural Heritage显示文摘A large number of unconventional investigations have been implemented, tested, and validated in the field of microgeophysics, with the aim being to solve specific diagnostic and/or monitoring problems regarding civil engineering and cultural heritage studies. The investigations were carried out using different tomographic 2D and 3D approaches as well as different energy sources, namely sonic, ultrasonic and electromagnetic (radar) waves, electric potential fields, and infrared thermography. Many efforts have been made to modify instruments and procedures in order to improve the resolution of the surveys as well as to greatly reduce the time of the measurements without any loss of information. The main new methodologies here discussed are the sonic imprint, the global tomographic traveltime, the electrical resistivity tomography, and the control of external films (patinas) grown on stone monuments. The results seem to be very promising and suggest that it is the moment to dedicate time and effort to this new branch of geophysics, so that these methodologies can be used even more to diagnose, monitor, and safeguard not only engineering buildings and large structures but also ancient monuments and cultural artifacts, like pottery, statues, etc.. | P L Cosentino P Capizzi G Fiandaca R Martorana P Messina | 2009 | Journal of China University of Geosciences2009，20，3： | 1 |
| 10 | A neural network approach for the differentiation of numerical solutions of 3-D electromagnetic problems 显示文摘 | Capizzi G Coco S Giuffrida C | 2004 | IEEE Transactions on Magnetics2004，40，2： | 1 |
| 11 | L-asparaginase显示文摘 | Capizzi RL Bertino JR Handschumacher RE | 1970 | Annu Rev Med1970，21，： | 1 |
| 12 | 25 (OH) vitamin D is associated with greater muscle strength in healthy men and women显示文摘 | GRIMALDI AS PARKER BA CAPIZZI JA | 2013 | Med Sci Sports Exe2013，45，1： | 1 |
| 13 | The preclinical basis for broad-spectrum selective cytoprotection of normal tissue from cytotoxic therapies by amifostine 显示文摘 | | 1999 | Semin Oncol1999，26，27： | 1 |
| 14 | Domain-independent neural underpinning of task-switching : an fMRI investigation 显示文摘 | Vallesi A Arbula S Capizzi M | 2015 | Cortex2015，65，： | 1 |
| 15 | The preclinical basis for broad-spectrumselective cytoprotection of normal tissues from cytotoxictherapies by amifostine显示文摘 | Capizzi RL | 1999 | Semin Oncol1999，26，27： | 1 |
| 16 | An Adaptive Exponentially Weighted Moving Average Control Chart显示文摘 | Giovanna Capizzi Guido Masarotto | 2003 | Technometrics2003，，3： | 1 |
| 17 | GADA titer-related risk for organ-specific autoimmunity in LADA subjects subdivided according to gender (NIRAD study 6)显示文摘 | Zampetti S Capizzi M Spoletini M | 2012 | J Clin Endocrinol Metab2012，97，10： | 1 |
| 18 | HIV-1 subtype E in Yunnan, China 显示文摘 | CHENG H ZHANG J CAPIZZI J | 1994 | Lancet1994，344，8927： | 1 |
| 19 | Peri-engraft-ment respiratory distress syndrome during autologous hematopoietie stem cell transplantation显示文摘 | Capizzi SA Kumar S Huneke NE | 2001 | Bone Marrow Transplant2001，27，12： | 1 |
| 20 | The preclinical basis for broad-spectrum selective cytoprotection of normal tissues from eytotoxic therapies by amifostine显示文摘 | CAPIZZI R L | 1996 | Europen Journal of Cancer1996，32，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员