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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Bench-to-bedside review:microvascular dysfunction in sepsis-hemodynamics,oxygen transport,and nitric oxide显示文摘 | Bateman R M Sharpe M D Ellis C G | 2003 | Crit Care2003，7，： | 1 |
| 3 | The enhanced infectivity of Metarhizium flavoviride in oil formulations to desert locusts at low humidities显示文摘 | Bateman RP Carey M Moore D | 1933 | Ann Appl Biol1933，122，： | 1 |
| 4 | Evaluation of Ruminally Protected Methionine and Lysine or Blood Meal and Fishmeal as Protein Sources for Lactating Holsteins显示文摘 | Bateman H D Spain J N Kerley M S | 1999 | J Dairy Sci1999，82，8： | 1 |
| 5 | Evaluation of ruminally protected methionine and lysine or blood meal and fish meal as protein sources for lactating Holsteins显示文摘 | Bateman H D Spain J N Kerley M S | 1999 | J Dairy Sci1999，82，： | 1 |
| 6 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley SD Chater KF Cerdeno-Tarraga AM Challis GL Thomson NR James KD Harris DE Quail MA Kieser H Harper D Bateman A Brown S Chandra G Chen CW Collins M Cronin A Fraser A Goble A Hidalgo J Hornsby T Howarth S Huang CH Kieser T Larke L Murphy L Oliver K O | | 0，，： | 1 |
| 7 | Origins of Nd-Sr-Pb isotopic variations in single scheelite grains from Arehaean gold deposits, Western Australia 显示文摘 | Brugger J Mass R Lahaye Y McRae C Ghaderi M Costa S Lam-bert D Bateman R Prince K | 2002 | Chemical Geology2002，182，： | 1 |
| 8 | Long-term storage of Metarhizium flavoviride conidia in oil formulation for the control of locust and grasshopper显示文摘 | Moore D Bateman RP Carey M | 1995 | Biocontrol Sci Technol1995，5，： | 1 |
| 9 | Salmeterol/Fluticason combination inhaler, a new, effective and we tolerate treatment for asthma显示文摘 | Bateman E D Britton M Corrilb J | 1999 | Clin Drug Invest1999，16，2： | 1 |
| 10 | Beach ridge plain evi denee of a variable late-Holocene tropical cyclone climate, North Queensland, Australia显示文摘 | Forsyth A J Nott J Bateman M D | 2010 | Palaeogeography Palaeoclimatology Palaeoecology2010，297，34： | 1 |
| 11 | Mid- to late-Holocene coastal dune event stratigraphy for the north coast of Northern Ireland显示文摘 | Wilson P McGourty J Bateman M D | 2004 | The Holocene2004，14，40： | 1 |
| 12 | Mortality study of 18 000 patients treated with omeprazole显示文摘 | Bateman DN Colin-Jones D Hartz S Langman M Logan RF Mant J | 2003 | Gut2003，52，： | 1 |
| 13 | The Pfam protein families database 显示文摘 | Punta M Coggill P C Eberhardt R Y Mistry J Tate J Boursnell C Pang N Forslund K Ceric G Clements J Hcger A Holm L Sonnhammer E L Eddy S R Bateman A Finn R D | 2012 | Nucleic Acids Research2012，40，： | 1 |
| 14 | Evaluation of ruminally protected methionine and lysine or blood meal and fishmeal as protein sources for lactating Holsteins显示文摘 | Bateman H D Spain J N Kerley M S | 1999 | Dairy Sci1999，82，： | 1 |
| 15 | Org Identification and structural analysis of synthetic oligosaccharides of shigella sonnei using MALDI-TOFMS显示文摘 | Harvey D J Rudd P M Bateman R H | 1994 | Mass Spectrom1994，29，： | 1 |
| 16 | Extrapyramidal reactions with metoclopramide 显示文摘 | D N Bateman M D Rawlins and J M Simpson | 1985 | Br Med J (Clin Res Ed )1985，5291，： | 1 |
| 17 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley SD Chater KF Cerdeno-Tarraga AM Challis GL Thomson NR James KD Harris DE Quail MA Kieser H Harper D Bateman A Brown S Chandra G Chen CW Collins M Cronin A Fraser A Goble A Hidalgo J Hornsby T Howarth S Huang CH Kieser T Larke L Murphy L Oliver K O | | 0，，： | 1 |
| 18 | 'All-in-one' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching显示文摘 | Wrona M Mauriala T Bateman KP Mortishire-Smith RJ O'Connor D | 2005 | Rapid Commun Mass Spectrom2005，19，18： | 1 |
| 19 | Combi- nation therapy with single inhaler budesonide/formoterol compared with high dose of fluticasone propionate alone in patients with moderate persistent asthma显示文摘 | Bateman E D Bantje T A Jofio Gomes M | 2003 | Am J Respir Med2003，2，3： | 1 |
| 20 | The enhanced infectivity of Metarhizium Flavoviride in oil formulations to desert locusts at low humidities显示文摘 | Bateman R P Carey M Moore D | 1993 | Annals of Applied Biology1993，122，： | 1 |
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