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| 1 | Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells显示文摘 | Charles N Ozawa T Squatrito M Bleau AM Brennan CW Hambardzumyan D Holland EC. | 2010 | 中国神经肿瘤杂志2010,8,1: | 24 |
| 2 | Late Mesozoic crust-mantle interaction in southeastern Fujian——Isotopic evidence from the Pingtan igneous complex显示文摘UNDERPLATING Of mantle-derived basaltic magma and interacting with the lower crust materials are believed to be an important mechanism for the growth and transformation of the crust. | Dong, CW Zhou, XM Li, HM Ren, SL Zhou, XH | 1997 | Chinese Science Bulletin1997,42,6: | 23 |
| 3 | A clinical and long-term follow-up study of perioperative sequential triple therapy for gastric cancer显示文摘INTRODUCTIONAlthough the long-term postoperative survival rateof gastric cancer(GC) patients has been improvedsignificantly since the local dissection of lymph nodewas widely used in China,yet the low curativeresection rate and the high recurrence rate fromperitoneal and hepatic metastases hinder it fromfurther improvement.To alter the currentunsatisfactory status of GC treatment,a | Zou SC Qiu HS Zhang CW Tao HQ | 2000 | World Journal of Gastroenterology2000,6,2: | 18 |
| 4 | Prospective validation of %p2PSA and the Prostate Health Index, in prostate cancer detection in initial prostate biopsies of Asian men, with total PSA 4-10 ng ml-1显示文摘尽管有它为屏蔽的前列腺癌症的普遍使用,低特性使 PSA 成为非最优的 biomarker,特别在 4-10 ng ml 1 的诊断灰色的地区。假积极与伴随的病态导致不必要的活体检视。这在与在 4.0 和 10 ng ml 1 之间的全部的 PSA 介绍的亚洲人是 % p2PSA 和前列腺健康索引(PHI ) 的第一未来的确认研究。我们学习了在 50 和 75 岁之间的 157 个亚洲人,与每直肠的前列腺考试的正常,经历他们的第一前列腺活体检视,用一个标准化活体检视协议,为 4-10 ng ml 1 的 PSA 层次。(19.1%) 三十被发现在活体检视上有前列腺癌症。有或没有前列腺癌症的病人之间的统计上重要的差别被作出对有利的裁决全部的 PSA, p2PSA, % p2PSA,和 PHI。在为全部的 PSA, % fPSA, % p2PSA,和 PHI 操作典型曲线的接收装置的曲线下面的区域分别地是 0.479, 0.420, 0.695,和 0.794。PHI 最好预言 prostatic 活体检视结果。在 90% 的敏感, PHI 的特性(95% CI ) 是 58.3% ,多于在 17.3% 点使全部的 PSA 的特性增加两倍,潜在地避免 77 (49%) 不必要的活体检视。类似于研究在主要白种人人口,我们有希望地证明了 % p2PSA 和 PHI 极大地超过总数并且释放总计 PSA 比率,在前列腺癌症的察觉起初活体检视。更高的 PHI 层次也对应于增加检测 GS 7 癌症的风险。我们验证了 PHI 的使用与在 4 和 10 ng ml 1 之间的浆液 PSA 在亚洲人关于前列腺活体检视帮助决策。 | Lincoln GL Tan Yung Khan Tan Bee Choo Tai Karen ML Tan Vineet Gauhar Ho Yee Tiong Robert CW Hawkins Thomas P Thamboo Felicia SK Hong Edmund Chiong | 2017 | Asian Journal of Andrology2017,19,3: | 13 |
| 5 | 聚氨酯和聚脲的傅里叶变换红外透射光谱的研究显示文摘用傅里叶变换红外透射光谱研究了溶液聚合的四种模型嵌段共聚物——聚氨酯-氨酯、聚脲-氨酯、聚氨酯-脲、聚脲-脲——在硬段微区和相界面区氢键的情况,并与衰减全射谱在分析这些模型嵌段共聚物时的情况进行了对比。 | 陈竹生 Yang WP Macosko CW | 1993 | 高分子材料科学与工程1993,9,3: | 9 |
| 6 | What are the ten new commandments in severe polytrauma management?显示文摘 | CW Kam CH Lai SK Lam FL So CL Lau KH Cheung | 2010 | World Journal of Emergency Medicine2010,1,2: | 9 |
| 7 | 心肺复苏的现代概念显示文摘现代心肺复苏(CPR)方法应用已三十年,确能挽救生命。本文对那些已明确和尚有争议的问题综述如下: 一、气道管理开放气道的传统方法是推头/托颈。但即使专业人员操作也常无效。推头/托颏似是较好方法,更有效但也较难掌握。 | Otto CW 傅文 | 1992 | 国外医学(麻醉学与复苏分册)1992,13,2: | 8 |
| 8 | 婚姻状况与心血管病风险的关系:系统评价和荟萃分析显示文摘虽然80%的未来心血管病风险可以从已知的心血管危险因素预测,如老年、男性、高血压、高血脂症、吸烟和糖尿病,但其余20%风险的决定因素仍不明确。婚姻对健康和死亡的益处已经在不同种族的两性中得到证实,并且与各种社会人口学特征无关。 | Wong CW Kwok CS Narain A Gulati M Mihalidou AS Wu P Alasnag M Myint PK Mamas MA 刘莉 叶鹏 | 2018 | 中华高血压杂志2018,26,9: | 5 |
| 9 | Geological thermal events in Tarim Basin显示文摘TARIM Basin is the biggest sedimentary basin in China, and it is also an important area of | Chen, HL Yang, SF Dong, CW Zhu, GQ Jia, CA Wei, GQ Wang, ZG | 1997 | Chinese Science Bulletin1997,42,7: | 5 |
| 10 | Correlation and prognostic significance of beta-galactoside alpha-2,6-sialyltransferase and serum monosialylated alpha-fetoprotein in hepatocellular carcinoma显示文摘AIM: To investigate the correlation between tissue ST6Gal I and serum msAFP in HCC patients, and to investigate their prognostic significance.METHODS: Preoperative sera,paired tumorous and non-tumorous tissues were collected from 19 consecutive patients who had undergone surgical resection of HCC.ST6Gal T activities in the tissues were measured by an in vitro microsomal enzyme activity assay. The percentages of tumor-specific msAFP in the sera were also estimated by an isoelectric focusing-immunoblotting assay.RESULTS: The tumor ST6Gal I activity was negatively correlated with serum msAFP percentage (r = -0.53,P = 0.019). Both decreased tumor ST6Gal I activity andincreased serum msAFP percentage were associatedwith poor tumor cell differentiation. Univariate analyses showed that both decreased tumor ST6Gal T activity (P = 0.028), increased serum msAFP percentage (P = 0.034) and poor tumor cell differentiation (P = 0.031)were associated with shorter overall survival. Multivariate analysis using the Cox regression model showed that the preoperative serum msAFP percentage (P = 0.022)and tumor cell differentiation status (P = 0.048) were independent prognostic indicators for patient overall survival.CONCLUSION: Our results indicate that the presence of msAFP in blood circulation is associated with a decreased activity of ST6Gal I activity in HCC. Both tissue ST6Gal I and serum msAFP are potential prognostic markers for patients with operable HCC. | Terence CW Poon Clarissa HS Chiu Paul BS Lai Tony SK Mok Benny Zee Anthony TC Chan Joseph JY Sung Philip J Johnson | 2005 | World Journal of Gastroenterology2005,11,42: | 4 |
| 11 | 基于现行高血压指南探究健康人群血清尿酸升高与高血压发病的相关性显示文摘本研究根据欧洲心脏病协会(European Society of Cardiology,ESC)和美国心脏病学会(American College of Cardiology,ACC)指南,探讨血清尿酸升高与高血压发病的相关性。方法和结果:本研究为回顾性研究,研究人员纳入年龄≥30岁、2016年接受常规年度体检并记录诊室血压数据的健康个体10 537人,其中7 349人2017年再次进行检查。高血压定义为诊室血压≥140/90(ESC指南)或130/80 mm Hg(1mm Hg=0.133kPa)(ACC指南)。 | 袁源(摘译) 郑武洪(审校) Liu CW Ke SR Tseng GS Wu YW Hwang JJ | 2021 | 中华高血压杂志2021,29,8: | 3 |
| 12 | Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome显示文摘Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiringventilatory support.We aimed to compare the efficacy of non-invasive ventilation against invasive mechanicalventilation treating respiratory failure in this disease.Methods Retrospective analysis was conducted on all respiratory failure patients identified from the HongKong Hospital Authority Severe Acute Respiratory Syndrome Database.Intubation rate, mortality and secondaryoutcome of a hospital utilizing non-invasive ventilation under standard infection control conditions ( NIVHospital) were compared against13 hospitals using solely invasive ventilation (IMVHospitals).Multiple logisticregression analyses with adjustments for confounding variables were performed to test for association betweenoutcomes and hospital groups.Results Both hospital groups had comparable demographics and clinical profiles, but NIV Hospital (42patients) had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid commencement.Compared to IMV Hospitals (451 patients), NIV Hospital had lower adjustedodds ratios for intubation (0.36, 95% CI 0.164 -0.791,P=0.011) and death (0.235, 95% CI 0.077 -0.716,P=0.011), and improved earlier after pulsed steroid rescue.There were no instances of transmission ofsevere acute respiratory syndrome among health care workers due to the use of non-invasive ventilation.Conclusion Compared to invasive mechanical ventilation, non-invasive ventilation as initial ventilatory supportfor acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated withreduced intubation need and mortality. | Loretta YC Yam Alfred YF Chan Thomas MT Cheung Eva LH Tsui Jane CK Chan Vivian CW Wong | 2005 | Chinese Medical Journal2005,,17: | 3 |
| 13 | Four cancer cases after esophageal atresia repair: Time to start screening the upper gastrointestinal tract显示文摘Esophageal atresia(EA) is one of the most common congenital digestive malformations and requires surgical correction early in life. Dedicated centers have reported survival rates up to 95%. The most frequent comorbidities after EA repair are dysphagia(72%) and gastroesophageal reflux(GER)(67%). Chronic GER after EA repair might lead to mucosal damage, esophageal stricturing, Barrett's esophagus and eventually esophageal adenocarcinoma. Several long-term follow-up studies found an increased risk of Barrett's esophagus and esophageal carcinoma in EA patients, both at a relatively young age. Given these findings, the recent ESPGHAN-NASPGHAN guideline recommends routine endoscopy in adults born with EA. We report a series of four EA patients who developed a carcinoma of the gastrointestinal tract: three esophageal carcinoma and one colorectal carcinoma in a colonic interposition. These cases emphasize the importance of lifelong screening of the upper gastrointestinal tract in EA patients. | Floor WT Vergouwe Madeleine Gottrand Bas PL Wijnhoven Hanneke IJsselstijn Guillaume Piessen Marco J Bruno René MH Wijnen Manon CW Spaander | 2018 | World Journal of Gastroenterology2018,24,9: | 3 |
| 14 | Expression of p53,inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions:correlation with clinical features显示文摘 | Feng CW Wang LD Jiao LH | 2002 | BMC Cancer2002,2,1: | 2 |
| 15 | 载脂蛋白E基因型影响老年人心输出量与认知功能的相关性显示文摘心输出量的轻微下降与低脑血流量相关,尤其是在阿尔茨海默病病理改变的首发区域。载脂蛋白E(apolipoprotein E,APOE)-ε4是阿尔茨海默病的一个遗传易感性危险因素,同时能减轻血管损伤。该研究旨在探讨携带APOE-ε4基因是否影响心输出量与认知功能的相关性。研究人员纳入范德比尔特记忆老化项目中无临床脑卒中和痴呆的参与者306例,平均年龄(73±7)岁,其中42%为女性。 | 陈嘉睿 刘莉 Bown CW Liu D Osborn KE Gupta DK Mendes LA Pechman KR Hohman TJ Wang TJ Gifford KA Jefferson AL | 2019 | 中华高血压杂志2019,27,10: | 2 |
| 16 | KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2显示文摘 | Dong JT Lamb PW Rinker Schaeffer CW | | 0,,: | 2 |
| 17 | Expression of estrogen receptor alpha and beta in the epiphyseal plate of the rat显示文摘 | Van der Eerden BC Gevers EF Lowik CW | 2002 | Bone2002,30,3: | 2 |
| 18 | New biochemical markers for myocardial cell injury显示文摘 | Hamm CW Katus HA | 1995 | Curr Opin Cardiol1995,10,4: | 2 |
| 19 | Identification and characterization of mutations in hepatitis B virus resistant to lamivudine显示文摘 | Allen MI Deslauriers M Andrews CW | | 0,,: | 2 |
| 20 | SURFACE INTEGRAL OF THREE-DIMENSIONAL VELOCITY FIELD FOR SQUARE BAR DRAWING THROUGH CONICAL DIE显示文摘SURFACEINTEGRALOFTHREE-DIMENSIONALVELOCITYFIELDFORSQUAREBARDRAWINGTHROUGHCONICALDIE¥ZhaoDewen;GuoChangwu;LiuXianghua(RollingT... | Zhao, DW Guo, CW Liu, XH Fang, YK | 1996 | 中国有色金属学会会刊:英文版1996,6,3: | 2 |