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| 1 | 杏仁核的功能连接与情绪性疼痛易化的个体差异相关显示文摘疼痛是一种复杂的体验,人与人之间的感知不同,甚至同一个人在不同情境下的感受也不一样。情绪状态可以调节疼痛体验,正性情绪缓解疼痛,而负性事件则易化疼痛感知。疼痛综合征和情感障碍的高共病率反映出了情绪和疼痛之间的密切关系。抑郁症病人罹患慢性疼痛的可能性是正常人的两倍。慢性疼痛病人常伴有类似于快感缺失的症状,包括疲惫感以及对以前愉悦活动参与的减少。 | 昝志(译) 顾楠(校) Gandhi W Rosenek NR Harrison R | 2020 | 中国疼痛医学杂志2020,26,12: | 8 |
| 2 | 评估清晨或夜晚服用降压药对24h动态血压的影响:清晨或夜间服用降压药的希腊英国联合研究显示文摘观察数据显示,临床血压水平与随后的主要不良心血管事件之间存在强烈的线性关系。然而,动态血压监测显示,夜间血压水平比24h或白天血压水平更能预测主要的不良心血管事件。此外,夜间与白天的血压比值和杓型状态也是心血管结局的重要独立预测因素。这些发现可能对抗高血压药物的最佳给药时间有影响,一些研究表明,夜晚服用降压药可能较白天服药减少心血管事件。 | Poulter NR Savopoulos C Anjum A Apostolopoulou M Chapman N Cross M Falaschetti E Fotiadis S James RM Kanellos I Szigeti M Thom S Sever P Thompson D Hatzitolios AI 赵狄 练桂丽 | 2018 | 中华高血压杂志2018,26,10: | 7 |
| 3 | 乙型肝炎疫苗和HBV感染诱导HBV特异性NK细胞记忆功能显示文摘【据Gut 2021年2月报道】题:乙型肝炎疫苗和HBV感染诱导HBV特异性NK细胞记忆功能(作者Wijaya RS等)接种乙型肝炎疫苗可通过免疫记忆保护机体免受后续感染(传统上被认为是适应性免疫系统的领域)。但在小鼠和非人类灵长类动物中发现了抗原特异性记忆自然杀伤细胞(mNK)后,这一观点受到了挑战。 | WIJAYA RS READ SA TRUONG NR 程俊雅 李海军 | 2021 | 临床肝胆病杂志2021,37,12: | 4 |
| 4 | Adult duodenal intussusception associated with congenital malrotation显示文摘Enteroenteric intussusception is a condition in which full-thickness bowel wall becomes telescoped into the lumen of distal bowel. In adults, there is usually an abnormality acting as a lead point, usually a Meckels' diverticulum, a hamartoma or a tumour. Duodeno-duodenal intussusception is exceptionally rare because the retroperitoneal situation fixes the duodenal wall. The aim of this report is to describe the first published case of this condition. A patient with duodeno-duodenal intussusception secondary to an ampullary lesion is reported. A 66 year-old lady presented with intermittent abdominal pain, weight loss and anaemia. Ultrasound scanning showed dilated bile and pancreatic ducts. CT scanning revealed intussusception involving the full-thickness duodenal wall. The lead point was an ampullary villous adenoma. Congenital partial (type Ⅱ) malrotation was found at operation and this abnormality permitted excessive mobility of the duodenal wall such that intussusception was possible. This condition can be diagnosed using enhanced CT. Intussusception can be complicated by bowel obstruction, ischaemia or bleeding, and therefore the underlying cause should be treated as soon as possible. | J Gardner-Thorpe RH Hardwick NR Carroll P Gibbs NV Jamieson RK Praseedom | 2007 | World Journal of Gastroenterology2007,13,28: | 3 |
| 5 | 脂质组学改善传统危险因素预测的2型糖尿病患者的心血管事件显示文摘临床脂质测定并未显示出糖尿病或心血管病相关的脂质代谢改变的复杂性。脂质组学则能够评估可作为疾病风险潜在标志物的数百种脂质种类。方法:纳入来自糖尿病治疗和血管保护行动。 | 刘莉 叶鹏 Alshehry ZH Mundra PA Barlow CK Mellett NA Wong G McConville MJ Simes J Tonkin AM Sullivan DR Barnes EH Nestel PJ Kingwell BA Marre M Neal B Poulter NR Rodgers A Williams B Zoungas S Hillis GS Chalmers J Woodward M Meikle PJ | 2016 | 中华高血压杂志2016,24,10: | 3 |
| 6 | Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease:a randomized trial显示文摘 | Albert CM Cook NR Gaziano JM | | Journal of the American Medical Association0,,: | 3 |
| 7 | Envionmental exposure to lead and childrens intelligence at the age of seven years:The port Pirie Cohort Study显示文摘 | Baghurst PA Mcmichael AJ Wigg NR | 1992 | Nengl J Med1992,275,: | 3 |
| 8 | 他克莫司和吲哚美辛可安全有效降低肝移植患者经内镜逆行胰胆管造影术后胰腺炎发生率显示文摘肝移植术后胆管并发症的发生率高达25%,且通常需要经内镜逆行胰胆管造影(ERCP)介入治疗。胰腺炎(PEP)是ERCP术后最常见的不良事件。他克莫司(一种钙调神经磷酸酶抑制剂)和直肠吲哚美辛均有报告可降低ERCP术后PEP的发生风险。来自美国加州大学旧金山分校等机构的研究者进行了一项回顾性队列分析,探讨了肝移植患者接受ERCP诊治的PEP发生率和他克莫司和(或)吲哚美辛降低PEP风险的有效性。 | 李家速 方军 THIRUVENGADAM NR FORDE KA CHANDRASEKHARA V | 2020 | 临床肝胆病杂志2020,36,7: | 2 |
| 9 | 健康女性隔日给予阿司匹林预防癌症、心血管疾病和胃肠道出血风险的个体化预测显示文摘阿司匹林在癌症和心血管疾病(cardiovascular disease,CVD)一级预防中的作用仍不清楚。该研究旨在确定女性使用阿司匹林治疗是否能改善发生癌症、CVD和重大消化道出血的风险。方法:对女性健康研究(一项随机试验,隔日服用阿司匹林100mg/安慰剂的临床实验)中拥有血浆样本的健康女性27 939人进行长期随访,个体化预测使用阿司匹林是否降低合并CVD、癌症和主要消化道出血的绝对风险。 | 刘莉 叶鹏 van Kruijsdijk RC Visseren FL Ridker PM Dorresteijn JA Buring JE van der Graaf Y Cook NR | 2014 | 中华高血压杂志2014,22,12: | 2 |
| 10 | Expression of cytochrome P4502E1 CYP2E1 in human liver:assessment of mRNA,genotype and phenotype 显示文摘 | Powell H Kitteringham NR Pirmohamed M | 1998 | Pharmacogenetics1998,8,: | 2 |
| 11 | 相对于男性,女性进行冠状动脉造影产生的额外的心血管病风险与严重受损的冠状动脉血流储备,而非阻塞性疾病相关显示文摘与男性相比,女性的心血管病死亡率更高,但是阻塞性冠状动脉疾病(coronary artery disease,CAD)在女性中不太普遍。冠状动脉血流储备(coronary flow reserve,CFR)是大、小血管CAD和心肌缺血的综合测量指标,可识别出具有心血管病死亡风险的患者,但其在临床实践中不是常规测量的指标。该研究试图调查性别、CFR和血管造影CAD严重程度对不良心血管事件的影响。 | 刘莉 叶鹏 Taqueti VR Shaw LJ Cook NR Murthy VL Shah NR Foster CR Hainer J Blankstein R Dorbala S Di Carli MF | 2016 | 中华高血压杂志2016,24,11: | 2 |
| 12 | 药剂师处方改善社区居民血压的随机试验:Alberta改善高血压临床试验显示文摘高血压控制率高居不下。执业药师的临床作用不断扩大,其在改善社区高血压治疗方面可能有较大帮助。该研究旨在确定药剂师处方对社区居住患者血压控制的影响。方法:研究人员进行随机对照试验,通过Alberta省23个社区药店、医院或基层医疗小组,纳入血压高于目标血压的成年患者。 | 刘莉 叶鹏 Tsuyuki RT Houle SK Charrois TL Kolber MR Rosenthal MM Lewanczuk R Campbell NR Cooney D McAlister FA | 2015 | 中华高血压杂志2015,23,7: | 2 |
| 13 | Renal Adenocarcinoma:CT Staging of 100 Tumors显示文摘 | Johnson CD Dunnick NR Cohan RH | 1987 | AJR1987,148,1: | 1 |
| 14 | Cancer gene therapy using a survivin mutant adenovirus显示文摘 | Mesri M Wall NR Li J | 2001 | J Clin Invest2001,105,7: | 1 |
| 15 | Adrenal irnaging: current status显示文摘 | Dunnick NR | 1990 | AJR1990,154,5: | 1 |
| 16 | Immunomagnetic isolation of osteoprogenitors from human bone marrow stroma 显示文摘 | Encina NR Billotte WG Hofmann MC | 1999 | Lab Invest1999,79,4: | 1 |
| 17 | Is prehospital bloodglucose measurement necessary in suspected cerebrovascular accident patients? 显示文摘 | Abarbanell NR | 2005 | Am J Emerg Med2005,23,7: | 1 |
| 18 | Assessment of genetic susceptibility to ethanol intoxication in mice 显示文摘 | Rustay NR Wahlsten D Crabbe JC | 2003 | Proc Natl Acad Sci USA2003,100,5: | 1 |
| 19 | A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women 显示文摘 | Ridker PM Cook NR Lee IM | 2005 | N Engl J Med2005,352,13: | 1 |
| 20 | Cancer gene therapy using a survivin mutant adenovirus 显示文摘 | Mesri M Wall NR Li J | 2001 | J Clin Invest2001,108,: | 1 |