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| 1 | Recent advances in endovascular techniques for management of acute nonvariceal upper gastrointestinal bleeding显示文摘Over the past two decades,transcatheter arterial embolization has become the first-line therapy for the management of upper gastrointestinal bleeding that is refractory to endoscopic hemostasis.Advances in catheter-based techniques and newer embolic agents, as well as recognition of the effectiveness of minimally invasive treatment options,have expanded the role of interventional radiology in the management of hemorrhage for a variety of indications,such as peptic ulcerbleeding,malignant disease,hemorrhagic Dieulafoy lesions and iatrogenic or trauma bleeding.Transcatheter interventions include the following:selective embolization of the feeding artery,sandwich coil occlusion of the gastroduodenal artery,blind or empiric embolization of the supposed bleeding vessel based on endoscopic findings and coil pseudoaneurysm or aneurysm embolization by three-dimensional sac packing with preservation of the parent artery.Transcatheter embolization is a fast,safe and effective,minimally invasive alternative to surgery when endoscopic treatment fails to control bleeding from the upper gastrointestinal tract.This article reviews the various transcatheter endovascular techniques and devices that are used in a variety of clinical scenarios for the management of hemorrhagic gastrointestinal emergencies. | Romaric F Loffroy Basem A Abualsaud Ming D Lin Pramod P Rao | 2011 | World Journal of Gastrointestinal Surgery2011，3，7： | 28 |
| 2 | Hypoalbuminemia in colorectal cancer prognosis:Nutritional marker or inflammatory surrogate?显示文摘Albumin is the single most abundant protein in the human serum. Its roles in physiology and pathology are diverse. Serum albumin levels have been classically thought to reflect the nutritional status of patients. This concept has been challenged in the last two decades as multiple factors, such as inflammation, appeared to affect albumin levels independent of nutrition. In general, cancer patients have a high prevalence of hypoalbuminemia. As such, the role of hypoalbuminemia in patients with colorectal cancer has received significant interest. We reviewed the English literature on the prognostic value of pretreatment albumin levels in colorectal cancer. We also consolidated the evidence that led to the current understanding of hypoalbuminemia as an inflammatory marker rather than as a nutritional one among patients with colorectal cancer. | Bassel Nazha Elias Moussaly Mazen Zaarour Chanudi Weerasinghe Basem Azab | 2015 | World Journal of Gastrointestinal Surgery2015，7，12： | 22 |
| 3 | Endoscopic closure of a gastrocolic fistula using the over-the-scope-clip-system显示文摘Gastrointestinal (GI) defects such as fistulas and leaks can be potentially closed endoscopically using hemo-clips and loops. However, hemoclips may not allow for closure of large defects and they do not exert enough tensile force to keep fibrotic defects larger than 5 mm approximated. Herein we present a case of successful endoscopic closure of a gastrocolic fistula in a severely malnourished patient with complex post-surgical upper GI anatomy. We strongly believe that this device is a major breakthrough for the management of various types of discontinuity defects or fistulas. In addition, we show the usefulness of placing a direct jejunostomy using the double balloon enteroscopy (DBE) technique during the same procedure. The concept of providing direct jejunal feedings while allowing for upper gas-trointestinal bowel rest to promote the healing of the minimally invasive endoscopic operation is novel. Thus, our case is unique and exemplifies the utility of mini-mally invasive endoscopic endoluminal surgery. | Klaus Mnkemüller Shajan Peter Basem Alkurdi Jayapal Ramesh Daniel Popa C Mel Wilcox | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，8： | 5 |
| 4 | Efficacy and safety of botulinum toxin in treatment of anismus: A systematic review显示文摘AIM: To evaluate the efficacy and safety of botulinum toxin type A(BTX-A) in the management of patients with anismus. METHODS: An organized search of published literature was conducted using electronic databases including: Pub Med/MEDLINE, and Cochrane Central Register of Control ed Trials, also an internet-based search using 'Google Scholar' service was conducted. Both comparative and observational studies were included. We excluded irrelevant articles, editorials, case reports, reviews, and meta-analyses. The studies that followed the patients less than 6 mo were excluded. Variables collected were demographic data of the patients, technique of BTX-A injection and number of sessions, short-term and longterm clinical improvement, post-injection changes in electromyography(EMG), defecography, manometry, and balloon expulsion test, and complications recorded after BTX-A injection.RESULTS: Seven studies comprising 189 patients were included in the review. The median age of the patients was 41.2 years and female-to-male ratio was 1.3:1. The median dose of BTX-A injected per procedure was 100 IU(range, 20-100 IU). Lateral injection was done in five trails and combined lateral and posterior injections in two trials. Three studies used endorectal ultrasonographyguided technique, one study used EMG-guided technique,whereas the remaining three studies used manual palpation with the index finger. The median percentage of patients who reported initial improvement of symptoms was 77.4%(range 37.5%-86.7%), this percentage declined to a median of 46%(range 25%-100%) at 4 mo after injection of BTX-A. Rates of improvement evaluated by balloon expulsion test, EMG, and defecography ranged between(37.5%-80%),(54%-86.7%), and(25%-86.6%), respectively. Fourteen(7.4%) patients developed complications after injection of BTX-A. Complication rates across the studies ranged from 0% to 22.6%. CONCLUSION: Initial satisfactory improvement of symptoms after BTX-A injection remarkably deteriorated after 3 mo of the procedure. However, repeated injection may provide better sustained results with no additional morbidities. Further analysis of more patients is necessary to conclude the safety of BTX-A for the treatment of anismus. | Sameh Hany Emile Hossam Ayman Elfeki Hosam Ghazy Elbanna Mohamed Youssef Waleed Thabet Tito M Abd El-Hamed Basem Said Ahmed Lotfy | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，3： | 3 |
| 5 | Survival and outcomes for co-infection of chronic hepatitis C with and without cirrhosis and COVID-19: A multicenter retrospective study显示文摘BACKGROUND Chronic liver disease,particularly cirrhosis,is associated with worse outcomes in patients infected with coronavirus disease 2019(COVID-19).AIM To assess outcomes of COVID-19 infection among patients with pre-existing hepatitis C with or without liver cirrhosis.METHODS This multicenter,retrospective cohort study included all cases of confirmed coinfection of severe acute respiratory syndrome coronavirus 2 and chronic hepatitis C with or without liver cirrhosis who were admitted to six hospitals(Al-Sahel Hospital,Al-Matareya Hospital,Al-Ahrar Hospital,Ahmed Maher Teaching Hospital,Al-Gomhoreya Hospital,and the National Hepatology and Tropical Medicine Research Institute)affiliated with the General Organization for Teaching Hospitals and Institutes in Egypt.Patients were recruited from May 1,2020,to July 31,2020.Demographic,laboratory,imaging features,and outcomes were collected.Multivariate regression analysis was performed to detect factors affecting mortality.RESULTS This retrospective cohort study included 125 patients with chronic hepatitis C and COVID-19 co-infection,of which 64(51.20%)had liver cirrhosis and 40(32.00%)died.Fever,cough,dyspnea,and fatigue were the most frequent symptoms in patients with liver cirrhosis.Cough,sore throat,fatigue,myalgia,and diarrhea were significantly more common in patients with liver cirrhosis than in noncirrhotic patients.There was no difference between patients with and without cirrhosis regarding comorbidities.Fifteen patients(23.40%)with liver cirrhosis presented with hepatic encephalopathy.Patients with liver cirrhosis were more likely than non-cirrhotic patients to have combined ground-glass opacities and consolidations in CT chest scans:28(43.75%)vs 4(6.55%),respectively(P value<0.001).These patients also were more likely to have severe COVID-19 infection,compared to patients without liver cirrhosis:29(45.31%)vs 11(18.04%),respectively(P value<0.003).Mortality was higher in patients with liver cirrhosis,compared to those with no cirrhosis:33(51.56%)vs 9(14.75%),respectively(P value<0.001).All patients in Child-Pugh class A recovered and were discharged.Cirrhotic mortality occurred among decompensated patients only.A multivariate regression analysis revealed the following independent factors affecting mortality:Male gender(OR 7.17,95%CI:2.19–23.51;P value=0.001),diabetes mellitus(OR 4.03,95%CI:1.49–10.91;P value=0.006),and liver cirrhosis(OR 1.103,95%CI:1.037–1.282;P value<0.0001).We found no differences in liver function,COVID-19 disease severity,or outcomes between patients who previously received direct-acting antiviral therapy(and achieved sustained virological response)and patients who did not receive this therapy.CONCLUSION Patients with liver cirrhosis are susceptible to higher severity and mortality if infected with COVID-19.Male gender,diabetes mellitus,and liver cirrhosis are independent factors associated with increased mortality risk. | Shimaa Afify Basem Eysa Fatma Abdel Hamid Omnia M Abo-Elazm Mohamed A Edris Rabab Maher Ahmed Abdelhalim Muhammad Mostafa Abdel Ghaffar Dalia A Omran Hend Ibrahim Shousha | 2021 | World Journal of Gastroenterology2021，27，42： | 2 |
| 6 | Controls on lode gold mineralization,Romite deposit,South Eastern Desert,Egypt显示文摘领域和遥感研究揭示那忍受 Au | Basem A.Zoheir | 2012 | Geoscience Frontiers2012，3，5： | 2 |
| 7 | 大西洋中脊26°S热液区玄武岩地球化学特征及其地幔源区性质显示文摘南大西洋中脊(SMAR)属于慢速扩张脊,26°S(SMAR 26°S)热液区是中国新近发现的以玄武岩为基岩的热液区。本次研究对热液区的玄武岩开展了岩相学和地球化学研究,揭示玄武岩的地球化学特征和岩浆源区性质,探讨其成矿潜力。结果表明,该热液区玄武岩地球化学特征和正常洋中脊玄武岩(N-MORB)相似,为钠质拉斑玄武岩;它们是由下伏亏损的尖晶石二辉橄榄岩地幔部分熔融而成。玄武岩所具有的低w(K2O)(0.05%~0.25%)、低(Ce/Yb)N比值(0.62~0.86),以及异常指数(Nb^*<1,P^*<1,Sr^*≤1,Zr^*>1)特征,表明源区地幔性质不均一,且受到了不同程度的陆壳物质混染;w(MgO)为7.52%~8.81%,指示热液区岩浆结晶分异程度低,岩浆演化不彻底。轻微的Eu正异常(δEu值为1.03~1.15),指示玄武岩形成过程中受到一定程度高温热液流体的影响,并处于强还原环境。与其他热液区玄武岩相比,研究区玄武岩Ba,Rb等高度不相容元素含量较低,均显示正Eu异常,岩石-海水相互作用弱。研究区玄武岩的Zn和Cu的含量分别为72.0~148.0×10^-6和79.9~138.5×10^-6,与MARK区和大西洋46°~32°S热液区玄武岩相比,研究区玄武岩可能具有更大的成矿潜力。 | 范蕾 王国芝 石学法 杨耀民 Holzheid Astrid Zoheir Basem A | 2020 | 矿物岩石2020，40，1： | 2 |
| 8 | 显示文摘 | Moustapha K Mahhe K Basem MA | 2004 | Basic Clin Pharmacol2004，11，： | 1 |
| 9 | Regulation of Human Skeletal Stem Cells Differentiation by Dlk1/Pref‐1显示文摘 | Basem MAbdallah Charlotte HJensen GloriaGutierrez Robert GQLeslie Thomas GJensen MoustaphaKassem | 2009 | J Bone Miner Res2009，，5： | 1 |
| 10 | Phase I/II Study of Bortezomib-BEAM and Autologous Hematopoietic Stem Cell Transplantation for Relapsed Indolent Non-Hodgkin Lymphoma, Transformed, or Mantle Cell Lymphoma显示文摘 | Basem M. William Mary S. Allen Fausto R. Loberiza R. Gregory Bociek Philip J. Bierman James O. Armitage Julie M. Vose | 2014 | Biology of Blood and Marrow Transplantation2014，，： | 1 |
| 11 | Long-term outcomes of surgery for malignant sacrococcygeal teratoma: 20-year experience of a regional UK centre显示文摘 | Basem A. Khalil Asher Aziz Pierina Kapur Gill Humphrey Antonino Morabito James Bruce | 2009 | Pediatric Surgery International2009，，3： | 1 |
| 12 | Colon cancer显示文摘 | Roberto Labianca Giordano D. Beretta Basem Kildani Laura Milesi Federica Merlin Stefania Mosconi M. Adelaide Pessi Tiziana Prochilo Antonello Quadri Gemma Gatta Filippo de Braud Jacques Wils | 2010 | Critical Reviews in Oncology and Hematology2010，，2： | 1 |
| 13 | Geochemical and geochronological characteristics of the Um Rus granite intrusion and associated gold deposit,Eastern Desert,Egypt显示文摘The Um Rus tonalite-granodiorite intrusion(~6 km2)occurs at the eastern end of the Neoproterozoic,ENE-trending Wadi Muba rak shear belt in the Central Eastern Desert of Egypt.Gold-bearing quartz veins hosted by the Um Rus intrusion were mined intermittently,and initially by the ancient Egyptians and until the early 1900 s.The relationship between the gold mineralization,host intrusion,and regional structures has always been unclear.We present new geochemical and geochronological data that help to define the tectonic environment and age of the Um Rus intrusion.In addition,field studies are integrated with EPMA and LA-ICP-MS data for gold-associated sulfides to better understand the formation and distribution of gold mineralization.The bulk-rock geochemical data of fresh host rocks indicate a calc-alkaline,metaluminous to mildly peraluminous,I-type granite signature.Their trace element composition reflects a tectonic setting intermediate between subduction-related and within-plate environments,presumably transitional between syn-and post-collisional stages.The crystallization age of the Um Rus intrusion was determined by in situ SHRIMP 206 Pb/238 U and 207Pb/235U measurements on accessory monazite grains.The resultant monazite U-Pb weighted mean age(643±9 Ma;MSWD 1.8)roughly overlaps existing geochronological data for similar granitic intrusions that are confined to major shear systems and are locally associated with gold mineralization in the Central Eastrn Desert(e.g.,Fawakhir and Hangaliya).This age is also consistent with magmatism recognized as concomitant to transpressional tectonics(D2:~650 Ma)during the evolution of the Wadi Mubark belt.Formation of the gold-bearing quartz veins in NNE-SSW and N-S striking fault segments was likely linked to the change from transpressional to transtensional tectonics and terrane exhumation(D3:620-580 Ma).The development of N-S throughgoing fault arrays and dike swarms(~595 Ma)led to heterogeneous deformation and recrystallization of the mineralized quartz veins.Ore minerals in the auriferous quartz veins include ubiquitous pyrite and arsenopyrite,with less abundant pyrrhotite,chalcopyrite,sphalerite,and galena.Uncommon pentlandite,gersdorffite,and cobaltite inclusions hosted in quartz veins with meladiorite slivers are interpreted as pre-ore sulfide phases.The gold-sulfide paragenesis encompasses an early pyrite-arsenopyrite±loellingite assemblage,a transitional pyrite-arsenopyrite assemblage,and a late pyrrhotite-chalcopyrite-sphalerite±galena assemblage.Free-milling gold/electrum grains(10 sμm-long)are scattered in extensively deformed vein quartz and in and adjacent to sulfide grains.Marcasite,malachite,and nodular goethite are authigenic alteration phases after pyrrhotite,chalcopyrite,and pyrite and arsenopyrite,respectively.A combined ore petrography,EPMA,and LA-ICP-MS study distinguishes morphological and compositional differences in the early and transitional pyrites(PyⅠ,PyⅡ)and arsenopyrite(ApyⅠ,ApyⅡ).Py I forms uncommon small euhedral inclusions in later PyⅡand Apy II.PyⅡforms large subhedral crystals with porous inner zones and massive outer zones,separated by narrow As-rich irregular mantles.The Fe and As contents in PyⅡare variable,and the LA-ICP-MS analysis shows erratic concentrations of Au(<1 to 177 ppm)and other trace elements(e.g.,Ag,Te,and Sb)in the porous inner zones,most likely related to discrete sub-microscopic sulfide inclusions.The outer massive zones have a rather homogenous composition,with consistently lower abundances of base metals and Au(mean 1.28 ppm).The early arsenopyrite(Apy I)forms fine-grained euhedral crystals enriched in Au(mean 17.7 ppm)and many other trace elements(i.e.,Ni,Co,Se,Ag,Sb,Te,Hg,and Bi).On the other hand,ApyⅡoccurs as coarsegrained subhedral crystals with lower and less variable concentrations of Au(mean 4 ppm).Elevated concentrations of Au(max.327 ppm)and other trace elements are measured in fragmented and aggregated pyrite and arsenopyrite grains,whereas the undeformed intact zones of the same grains are poor in all trace elements.The occurrence of gold/electrum as secondary inclusions in deformed pyrite and arsenopyrite crystals indicates that gold introduction was relatively late in the paragenesis.The LAICP-MS results are consistent with gold redistribution by the N-S though-going faults/dikes overprinted the earlier NNW-SSE quartz veins in the southeastern part of the intrusion,where the underground mining is concentrated.Formation of the Um Rus intrusion and gold-bearing quartz veins can be related to the evolution of the Wadi Mubarak shear belt,where the granitic intrusion formed during or just subsequent to D2 and provided dilatation spaces for gold-quartz vein deposition when deformed by D3 structures. | Basem Zoheir Richard Goldfarb Astrid Holzheid Hassan Helmy Ahmed El Sheikh | 2020 | Geoscience Frontiers2020，11，1： | 1 |
| 14 | Equivalent survival following liver transplantation in patients with non‐alcoholic steatohepatitis compared with patients with other liver diseases显示文摘 | Christopher Kennedy David Redden Stephen Gray Devin Eckhoff Omar Massoud Brendan McGuire Basem Alkurdi Joseph Bloomer Derek A. DuBay | 2012 | HPB2012，，9： | 1 |
| 15 | Ophthalmic injuries in patients with zygomaticomaxillary complex fractures requiring surgical repair显示文摘 | Basem J | | 0，，： | 1 |
| 16 | Dexmedetomidine as sole sedative for awake intubation in management of the critical airway显示文摘 | Basem Abdelmalak Laila Makary Jeremy Hoban D. John Doyle | 2007 | Journal of Clinical Anesthesia2007，，5： | 1 |
| 17 | Usefulness of Neutrophil to Lymphocyte Ratio in Predicting Short- and Long-Term Mortality After Non–ST-Elevation Myocardial Infarction显示文摘 | Basem Azab Medhat Zaher Kera F. Weiserbs Estelle Torbey Kenson Lacossiere Sainath Gaddam Romel Gobunsuy Sunil Jadonath Duccio Baldari Donald McCord James Lafferty | 2010 | The American Journal of Cardiology2010，，4： | 1 |
| 18 | Mesenchymal stem cells:cell biology and potential use in therapy显示文摘 | Moustapha Kassem Malthe Kristiansen Basem M | 2004 | Basic & Clinical Pharmacology & Toxicology2004，95，： | 1 |
| 19 | Real-Time QoS-Aware Video Streaming: A Comparative and Experimental Study显示文摘 | Basem Al-Madani Anas Al-Roubaiey Zubair A. Baig Costas Kotropoulos | 2014 | Advances in Multimedia2014，，： | 1 |
| 20 | Can blockchain link the future?显示文摘Recently,decentralization has been extensively explored by researchers.Blockchain,as a representation of decentralized technology,has attracted attention with its unique characteristics,such as irrevocability and security.Consequently,herein,we introduce cutting-edge blockchain technologies from four directions:blockchain system,consensus algorithms,smart contract,and scalability.Subsequently,we analyze the current lack of consensus mechanism,fault tolerance,and block capacity of the blockchain,and the integration of blockchain into 5G/6G mobile communication.Furthermore,we discuss the possible applications of blockchain in intellectual property protection,the Internet of Things,digital twins,standardization,and epidemic prevention and control.Finally,explore the impacts and solutions of blockchain on human society beyond technology. | Liang Qiao Shuping Dang Basem Shihada Mohamed-Slim Alouini Robert Nowak Zhihan Lv | 2022 | Digital Communications and Networks2022，8，5： | 1 |
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