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| 1 | 镇江市古运河和金山湖河湖上覆水体和沉积物氮及有机质分布特征及污染评价显示文摘镇江市位于长江和京杭大运河'十字黄金水道'的交汇处,是我国历史上最为重要的水上交通枢纽之一,区域内水量充沛、河网密布.近年来,该区域水环境存在不同程度的退化,故调查镇江市主要河湖水体及沉积物污染现状,将为当地水环境质量的改善提供重要的基础数据.基于此,本研究选择镇江市典型河湖水体共21个点位(金山湖10个点位,古运河及其支流共11个点位),在冬夏两季采集上覆水及沉积物样品测定其理化指标和氮素含量,并通过有机指数及有机氮对沉积物污染程度进行评价.结果表明:(1)上覆水总氮(TN)浓度在冬夏季节分别介于1.95~15.71 mg·L^(-1)和0.64~12.09 mg·L^(-1)之间,平均值为4.01 mg·L^(-1)和4.07 mg·L^(-1),平均值浓度高于地表水Ⅴ类标准.上覆水氨氮(NH^(+)_(4)-N)浓度在季节上均表现为冬季<夏季,空间上则表现为河流>湖泊;(2)沉积物TN含量在冬夏两季分别介于394.61~3288.09 mg·kg^(-1)和869.21~3598.04mg·kg^(-1)之间,平均值为1928.58 mg·kg^(-1)和2068.40 mg·kg^(-1).湖泊沉积物TN、NH^(+)_(4)-N、硝态氮(NO^(-)_(3)-N)和有机氮(Org-N)含量均表现为冬季>夏季,而河流沉积物TN平均含量为冬季<夏季,NH^(+)_(4)-N和NO^(-)_(3)-N则表现为冬季>夏季,表明河流沉积物在季节上的分布规律更为复杂;空间上,冬夏两季沉积物NO^(-)_(3)-N表现为湖泊>河流,NH^(+)_(4)-N含量则表现为湖泊<河流.C/N结果表明研究区域沉积物有机质主要来源于内源污染;(3)湖泊和河流沉积物超过60%点位属于有机氮污染Ⅳ水平,即存在有机氮污染,而超过70%和54.55%的湖泊和河流沉积物处于有机指数Ⅱ类水平,即较清洁水平,表明镇江市河湖沉积物主要为氮素污染.以上研究结果将为镇江市河流水体及沉积物氮素控制提供重要的基础数据. | 原璐彬 邢书语 刘鑫 周晓红 Adelaide Angela Dadzie | 2021 | 环境科学2021，42，7： | 6 |
| 2 | Preparation and investigation of Pd doped Cu catalysts for selective hydrogenation of acetylene显示文摘A series of PdCu bimetallic catalysts with low Cu and Pd loadings and different Cu:Pd atomic ratios were prepared by conventionally sequential impregnation(CSD)and modified sequential impregnation(MSI)of Cu and Pd for selective hydrogenation of acetylene.Characterization indicates that the supported copper(I)nitrate in the PdCu bimetallic catalysts prepared by MSI can be directly reduced to Cu metal particles due to the hydrogen spillover from Pd to Cu(NO3)2 crystals.In addition,for the catalysts prepared by MSI,Pd atoms can form PdCu alloy on the surface of metal particles,however,for the catalysts prepared by CSI,Pd tends to migrate and exist below the surface layer of Cu.Reaction results indicate that compared with CSI,the MSI method enables samples to possess preferable stability as well as comparable reaction activity.This should be due to the MSI method in favor of the formation of PdCu alloy on the surface of metal particles.Moreover,even Pd loading is super low,<0.045 wt-%in this study,by through adjusting Cu loading to an appropriate value,attractive reactivity and selectivity still can be achieved. | Xinxiang Cao Tengteng Lyu Wentao Xie Arash Mirjalili Adelaide Bradicich Ricky Huitema Ben W.-L.Jang Jong K.Keum Karren More Changjun Liu Xiaoliang Yan | 2020 | Frontiers of Chemical Science and Engineering2020，14，4： | 4 |
| 3 | Smad3 knock-out mice as a useful model to study intestinal fibrogenesis显示文摘瞄准:为了在形态学和免疫评估可能的差别, CD3,转变生长因素 beta1 (TGF-beta1 ) , Smad7, alpha 光滑的肌肉肌动朊(alpha-Sma ) ,和骨胶原的组织化学的表示打 I-VII 小并且在 Smad3 空、野类型的老鼠的大肠。方法:十 0 和十只野类型的成年老鼠在年龄和机关的 4 瞬间被牺牲(食管,小、大的肠,输尿管) 为组织学被收集(苏木精和曙红,马森 thrichrome,染色的银) ,形态测定法和免疫组织化学分析。肠的织物 homogenates 的 TGF-beta1 层次被 ELISA 估计。结果:没有宏观的肠的损害在空、野类型的老鼠两个都被检测。组织学并且 morphometric 评估在肌肉层厚度揭示了重要减小小并且在空老鼠的大肠同样与野类型的老鼠相比。Immunohistochemistry 评估显示出染色在的 CD3+ T 房间, TGF-beta1 和 Smad7 的重要增加小并且 Smad3 空老鼠的大肠粘膜同样与野类型的老鼠相比。染色的 Alpha-Sma 和骨胶原 I-VII 小并且大肠没在二组老鼠之间不同。结肠的织物 homogenates 的 TGF-beta1 层次比在野类型的老鼠在空老鼠是显著地更高的。在初步的实验,导致 TNBS 的肠的纤维变性的重要减小作为与野类型的老鼠相比在空老鼠被观察。结论:Smad3 空老鼠是一个有用模型调查在肠的发炎和纤维变性表明小径的 TGF-beta/Smad 的在活体内角色。 | Giuliana Zanninelli Antonella Vetuschi Roberta Sferra Angela D'Angelo Amato Fratticci Maria Adelaide Continenza Maria Chiaramonte Eugenio Gaudio Renzo Caprilli Giovanni Latella | 2006 | World Journal of Gastroenterology2006，12，8： | 3 |
| 4 | Intravenous immune globulin suppresses angiogenesis in mice and humans显示文摘Human intravenous immune globulin(IVIg),a purified IgG fraction composed of~60%IgG1 and obtained from the pooled plasma of thousands of donors,is clinically used for a wide range of diseases.The biological actions of IVIg are incompletely understood and have been attributed both to the polyclonal antibodies therein and also to their IgG(IgG)Fc regions.Recently,we demonstrated that multiple therapeutic human IgG1 antibodies suppress angiogenesis in a target-independent manner via FcγRI,a high-affinity receptor for IgG1.Here we show that IVIg possesses similar anti-angiogenic activity and inhibited blood vessel growth in five different mouse models of prevalent human diseases,namely,neovascular age-related macular degeneration,corneal neovascularization,colorectal cancer,fibrosarcoma and peripheral arterial ischemic disease.Angioinhibition was mediated by the Fc region of IVIg,required FcγRI and had similar potency in transgenic mice expressing human FcγRs.Finally,IVIg therapy administered to humans for the treatment of inflammatory or autoimmune diseases reduced kidney and muscle blood vessel densities.These data place IVIg,an agent approved by the US Food and Drug Administration,as a novel angioinhibitory drug in doses that are currently administered in the clinical setting.In addition,they raise the possibility of an unintended effect of IVIg on blood vessels. | Reo Yasuma Valeria Cicatiello Takeshi Mizutani Laura Tudisco Younghee Kim Valeria Tarallo Sasha Bogdanovich Yoshio Hirano Nagaraj Kerur Shengjian Li Tetsuhiro Yasuma Benjamin J Fowler Charles B Wright Ivana Apicella Adelaide Greco Arturo Brunetti Balamurali K Ambati Sevim Barbasso Helmers Ingrid E Lundberg Ondrej Viklicky Jeanette HW Leusen J Sjef Verbeek Bradley D Gelfand Ana Bastos-Carvalho Sandro De Falco Jayakrishna Ambati | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 3 |
| 5 | Acute hepatitis after amiodarone infusion显示文摘Acute hepatitis is a very rare, but potentially fatal, adverse effect of intravenous amiodarone. We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy and severely depressed left ventricular function that was admitted to our coronary care unit with diagnosis of decompensated heart failure and non-sustained ventricular tachycardia. A few hours after the beginning of intravenous amiodarone he developed an acute hepatitis. There was a completely recovery within the next days after amiodarone withdrawn and other causes of acute hepatitis have been ruled out. This case highlights the need for close monitoring of hepatic function during amiodarone infusion in order to identify any potential hepatotoxicity and prevent a fatal outcome. Oral amiodarone is, apparently, a safe option in these patients. | Paulo Fonseca Adelaide Dias Helena Gonçalves Aníbal Albuquerque Vasco Gama | 2015 | World Journal of Clinical Cases2015，3，10： | 2 |
| 6 | Assessing nutrient losses with soil erosion under different tillage systems and their implications on water quality 显示文摘 | Adelaide M | 2007 | Physics and Chemistry of the Earth2007，32，： | 1 |
| 7 | Expression ofFGF and FGF receptor genes in human breast cancer显示文摘 | H Penault-Llorca F Bertucci F Adelaide J | 1995 | Int JCancer1995，61，2： | 1 |
| 8 | Antifungal activity of transparent nanocomposite thin films of pullulan and silver against Aspergillus niger显示文摘 | Ricardo J.B. Pinto Adelaide Almeida Susana C.M. Fernandes Carmen S.R. Freire Armando J.D. Silvestre Carlos Pascoal Neto Tito Trindade | 2013 | Colloids and Surfaces B: Biointerfaces2013，，： | 1 |
| 9 | New types of MYST3CBP and CBP-MYST3 fusion transcripts in t (8,16) (p11, p13) a cute myeloid leukemias 显示文摘 | Murati A Adelaide J Quiliehini B | 2007 | Haematologica2007，92，2： | 1 |
| 10 | Progressive truncation of the non- structural 1 gene of H7N1 avian influenza viruses following extensive circulation in poultry显示文摘 | William G D Adelaide M Giovanni C | 2006 | Virus Res2006，119，2： | 1 |
| 11 | Colon cancer显示文摘 | Roberto Labianca Giordano D. Beretta Basem Kildani Laura Milesi Federica Merlin Stefania Mosconi M. Adelaide Pessi Tiziana Prochilo Antonello Quadri Gemma Gatta Filippo de Braud Jacques Wils | 2010 | Critical Reviews in Oncology and Hematology2010，，2： | 1 |
| 12 | Descriptors of dyspnea by patients with chronic obstructive pulmonary dis ease versus congestive heart failure显示文摘 | Adelaide SC Suzanne CL Loma L | 2004 | Heart Lung2004，33，2： | 1 |
| 13 | Early signs of atheroscle- rosis in Obstructive Sleep Apnea显示文摘 | Luciano FD Luiz AB Adelaide CF | 2005 | Am J Respir Crit Care Med2005，172，5： | 1 |
| 14 | Nephrolithiasis is associated with an increased prevalence of cardiovascular disease显示文摘 | Fernando D Adelaide S | 2011 | Nephrol Dial Transplant2011，26，3： | 1 |
| 15 | A t(8;9) translocation with PCM1-JAK2 fusion in a patient with T-cell lymphoma显示文摘 | Adelaide J Perot C Gelsi-Boyer V | 2006 | Leukemia2006，20，： | 1 |
| 16 | Freeze Rubens Maciel Filho, Eduardo drying process: real time model and optimization显示文摘 | Edinara Adelaide Boss Coselli Vasco de Toledo | 2004 | Chemical Engineering and Processing2004，43，： | 1 |
| 17 | Descriptors of dyspnea by patients with chronic obstructive pulmonary disease versus congestive heart failure 显示文摘 | Adelaide S C Suzanne C L Loma L | 2004 | Heart Lung2004，33，2： | 1 |
| 18 | Detailed map of a re- gion commonly amplified at llq13 - - > q14 in human breast carcinoma显示文摘 | Bekri S Adelaide J Merscher S | 1997 | Cytogenet Cell Genet1997，79，12： | 1 |
| 19 | The HMGA1-IGF-I/IGFBP System: A Novel Pathway for Modulating Glucose Uptake显示文摘 | Stefania Iiritano Eusebio Chiefari Valeria Ventura Biagio Arcidiacono Katiuscia Possidente Aurora Nocera Maria T. Nevolo Monica Fedele Adelaide Greco Manfredi Greco Giuseppe Brunetti Alfredo Fusco Daniela Foti Antonio Brunetti | 2012 | Molecular Endocrinology2012，，9： | 1 |
| 20 | Mutations and deletions of AR- IDIA in breast tumors显示文摘 | Cornen S Adelaide J Bertucci F | 2012 | Oncogene2012，31，38： | 1 |
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