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1Diagnostic dilemma of abdominal tuberculosis in non-HIV patients:An ongoing challenge for physicians显示文摘AIM: To assess the clinical features, yield of the diagnostic tests and outcome of abdominal tuberculosis in non-HIV patients. METHODS: Adult patients with discharge diagnosis of abdominal tuberculosis (based upon; positive microbiology, histo-pathology, imaging or response to trial of anti TB drugs) during the period 1999 to 2004 were analyzed. Patient’s characteristics, laboratory investigations, radiological, endoscopic and surgical findings were evaluated. Abdominal site involved (intestinal, peritoneal, visceral, and nodal) and response to treatment was also noted. RESULTS: There were 209 patients enrolled. One hundred and twenty-three (59%) were females. Symptoms were abdominal pain 194 (93%), fever 134 (64%), night sweats 99 (48%), weight loss 98 (47%), vomiting 75 (36%), ascites 74 (35%), constipation 64 (31%), and diarrhea 25 (12%). Sub-acute and acute intestinal obstruction was seen in 28 (13%) and 12 (11%) respectively. Radiological evidence of pulmonary tuberculosis was found in 134 (64%) patients. Basis of diagnosis of abdominal tuberculosis were radiology (Chest and barium X-Rays, Ultrasound and CT scan abdomen) in 111 (53%) and histo-pathology (tissue obtained during surgery, colonoscopy, CT or ultrasound guided biopsy, laparoscopy and upper gastro intestinal endoscopy) in 87 (42%) patients. Mycobacterium culture was positive in 6/87 (7%) patients and response to therapeutic trial of anti tubercular drugs was the basis of diagnosis in 5 (2.3%) patients. Predominant site of involvement by abdominal TB was intestinal in 103 (49%) patients, peritoneal in 87 (42%) patients, solid viscera in 10 (5%) and nodal in 9 (4%) patients. Response to medical treatment was found in 158 (76%) patients andadditionally 35 (17%) patients also underwent surgery. In a 425 ± 120 d follow-up period 12 patients died (eight post operative) and no case of relapse was noted. CONCLUSION: Abdominal TB has diverse and non- specific symptomatology. No single test is adequate for diagnosis of abdominal tuberculosis in all patients. Abdominal TB in non-HIV patients remains an ongoing diagnostic dilemma requiring a high index of clinical suspicion.Rustam Khan Shahab Abid Wasim Jafri Zaigham Abbas Khalid Hameed Zubair Ahmad 2006World Journal of Gastroenterology2006,12,39:17
2磁性纳米材料:化学合成、功能化与生物医学应用显示文摘磁性纳米材料,由于其独特的磁学性能、小尺寸效应,被广泛应用于生物医学领域.本文总结了磁性纳米材料的化学设计与合成、表面功能化方法,及其在核磁共振成像、磁控治疗、磁热疗和生物分离等生物医学领域的应用进展.余靓 刘飞 Muhammad Zubair Yousaf 侯仰龙 2013生物化学与生物物理进展2013,40,10:15
3宰后僵直和解僵过程羊肉风味品质分析显示文摘本文研究了4 ℃贮藏条件下,羊肉僵直和解僵过程中风味品质的变化。以羊背最长肌为研究对象,采用超快速气相电子鼻和气相色谱质谱联用技术(Gas Chromatography-Mass Spectrometer,GC-MS),测定宰后不同贮藏时间羊肉挥发性风味物质的差异。结果表明,宰后贮藏过程中共检测出挥发性风味物质6类51种,主要为醛类和醇类物质,随着贮藏时间的延长,熟制羊肉的醛类物质含量先增加后降低,醇类物质的含量先降低后增加,己醛、庚醛、辛醛、壬醛、1-戊醇、1-辛烯-3-醇和1-庚醇为宰后贮藏过程中羊肉的关键风味物质,宰后1 d与1 h羊肉的共有关键风味物质含量无显著差异(p>0.05),宰后 3 d 和 5 d羊肉的风味物质种类和含量降低;超快速气相电子鼻主成分分析结果与 GC-MS 结果相一致。因此,僵直前(宰后 1 h)和解僵初期(宰后 1 d)羊肉的共有关键风味物质种类和含量差异不显著,解僵后期(宰后 3 d 和 5 d)羊肉关键风味物质含量和种类明显降低。肖雄 张德权 李铮 李欣 任驰 Zubair Hussain 刘登勇 侯成立 2019现代食品科技2019,35,6:12
4Survey and technological analysis of laser and its defense applications显示文摘The laser technology has made remarkable progress over the past couple of decades.It is being widely employed in diverse domains,such as holography,space sciences,spectroscopy,medical sciences,micro and power electronics,industrial engineering,and most distinctively,as directed energy military weapons.Owing to their active transmissions,laser systems are similar to microwave radars to some extent;however,unlike conventional radars,the laser operates at very high frequencies thus making it a potent enabler of narrow-beam and high energy aerial deployments,both in offensive and defensive roles.In modern avionics systems,laser target indicators and beam riders are the most common devices that are used to direct the Laser Guided Weapons(LGW)accurately to the ground targets.Additionally,compact size and outstanding angular resolution of laser-based systems motivate their use for drones and unmanned aerial applications.Moreover,the narrow-beam divergence of laser emissions offers a low probability of intercept,making it a suitable contender for secure transmissions and safety-critical operations.Furthermore,the developments in space sciences and laser technology have given synergistic potential outcomes to use laser systems in space operations.This paper comprehensively reviews laser applications and projects for strategic defense actions on the ground or in space.Additionally,a detailed analysis has been done on recent advancements of the laser technology for target indicators and range-finders.It also reviews the advancements in the field of laser communications for surveillance,its earlier state of the art,and ongoing scientific research and advancements in the domain of high energy directed laser weapons that have revolutionized the evolving military battlefield.Besides offering a comprehensive taxonomy,the paper also critically analyzes some of the recent contributions in the associated domains.Syed Affan Ahmed Mujahid Mohsin Syed Muhammad Zubair Ali 2021Defence Technology(防务技术)2021,17,2:10
5Prevalence and interrelationships of foot ulcer, risk-factors and antibiotic resistance in foot ulcers in diabetic populations: A systematic review and meta-analysis显示文摘BACKGROUND Diabetic foot ulceration(DFU)is the prime health concern globally.It accounts for the major burden related to disease mortality and morbidity and economic cost.The timely and early recognition of the DFU can help present its occurrence and improve clinical outcomes.AIM To evaluate interrelationships between foot ulcers,risk factors,and antibiotic resistance among diabetic patients having ulcers in their foot.METHODS The databases such as PubMed,ERIC,Medline,and Google Scholar were extensively used for the extraction of studies.The selected studies were published within the time-period of 2014-2018.Ten studies were selected,which were found to be completely relevant to the current study.RESULTS The prevalence of diabetic foot ulcers among the population was evaluated,and the associated risk factors with its prevalence.Moreover,few studies also reported on the bacteria that are found to be most prevailing among diabetic patients.A narrative discussion was drawn through this analysis,which was used to highlight the specific area of research through selected studies,extraction of the significant information that matched with the topic of research,and analysis of problem through the findings of the selected articles.The results helped in assessing significant knowledge regarding the risk factors of diabetic foot ulcers and the role of antimicrobial resistant in its treatment.CONCLUSION The gram-negative bacteria were found to be the most common reason for diabetic foot ulcers.The study only included 10 studies that are not sufficient to produce generalized results,and no information was reported on the tests required to analyze antimicrobial susceptibility that can guide clinicians to propose better and sound treatment plans.It is evident that most study results depicted that the most common risk factors were found to be hypertension and neuropathy.Mohammad Zubair 2020World Journal of Diabetes2020,11,3:6
6Experimental and Numerical Investigation of the Effects of Passive Vortex Generators on Aludra UAV Performance显示文摘A study of the effects of passive vortex generators (VGs) on Aludra unmanned aerial vehicle (UAV) aerodynamic characteristics is presented. Both experimental and numerical works are carried out where an array of VGs is attached on Aludra UAV's wing. The flow measurements are made at various angles of attack by using 3-axis component balance system. In the numerical investigation, the Reynolds-averaged Navier-Stokes (RANS) code FLUENT 6.3TM is used in the simulations with fully structured mesh with Spalart-Allmaras (S-A) turbulence model and standard wall function. The comparison between the experimental and numerical results reveals a satisfactory agreement. The parametric study shows that higher maximum lift coefficient is achieved when the VGs are placed nearer to the separation point. In addition to this, shorter spanwise distance between the VGs also increases the maximum lift coefficient, rectangular and curve-edge VG performs better than triangular VG.Tan Kar ZHEN Muhammed ZUBAIR Kamarul Arifin AHMAD 2011Chinese Journal of Aeronautics2011,24,5:6
7Decorin treatment of spinal cord injury显示文摘The scarring response after a penetrant central nervous system injury results from the interaction between invading leptominingeal/pericyte-derived fibroblasts and endogenous reactive astrocytes about the wound margin. Extracellular matrix and scar-derived axon growth inhibitory molecules fill the lesion site providing both a physical and chemical barrier to regenerating axons. Dec orin, a small leucine-rich chondroitin-dermatan sulphate proteoglycan expressed by neurons and astrocytes in the central nervous system, is both anti-fibrotic and anti-inflammatory and attenuates the formation and partial dissolution of established and chronic scars. Here, we discuss the potential of using Decorin to antagonise scarring in the central nervous system.Maryam Esmaeili Martin Berry Ann Logan Zubair Ahmed 2014Neural Regeneration Research2014,9,18:5
8氧化锌纳米颗粒的形貌控制合成及其体外抗菌活性显示文摘在不使用任何表面活性剂或模板的情况下,采用可控沉淀法在水溶液中成功合成形貌均匀的分层花状和纳米棒状氧化锌(ZnO)。为了阐明纳米颗粒的生长机理,系统研究pH、反应时间和温度对纳米颗粒形貌的影响。采用SEM、FT-IR和XRD等表征手段对样品进行分析。XRD谱证实合成的粉末具有良好的结晶性。此外,对比研究合成的花状(ZnO-1)和纳米棒状(ZnO-2)的ZnO纳米颗粒与商业ZnO(ZnO-Com)颗粒的体外抗菌活性。结果表明,在实验条件下,ZnO-2比ZnO-1对受试菌具有更高的抗菌活性,而商业ZnO则没有抗菌活性。当ZnO-2的浓度从0.25升高到0.75μg/μL时,对变异链球菌的抑菌环从约30 mm扩大到33 mm,对大肠杆菌的抑菌环从约28mm增大到30mm。研究表明,合成的氧化锌纳米颗粒作为抗菌剂,可能在生物医学方面有效抑制某些致病菌。Naila ZUBAIR Khalida AKHTAR 2020Transactions of Nonferrous Metals Society of China2020,30,6:4
9Effect of seedling age and water depth on morphological and physiological aspects of transplanted rice under high temperature显示文摘To study the effect of high temperature, rice seedlings 20, 30, 40 and 50 d were kept at 5, 10, 15 and 20 cm water depth in a water pool. Meteorological findings indicated that water temperature varied up to 10 cm but became stable below this depth. Deep water inflicted higher tiller mortality, minimal increase in dry weight of aerial parts and leaf area, decrease in root length, and decrease in root dry weight especially at 20 cm water depth and produced an unbalanced T/R ratio (top versus root dry weight). However, deep water tended to increase plant length. These parameters, however, excel in shallow water. Older seedlings, with the exception of root dry weight, could not perform well compared to young seedlings in all physiological and morphological aspects. The study revealed that seedlings, particularly young ones, stand well in shallow water and can cope with high temperature.KHAKWANI Abdul Aziz SHIRAISHI Masaaki ZUBAIR Muhammad BALOCH Mohammad Safdar NAVEED Khalid AWAN Inayatullah 2005Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2005,6,5:4
10Gastric juice for the diagnosis of H pylori infection in patients on proton pump inhibitors显示文摘AIM: To determine the efficacy of gastric juice polymerase chain reaction (PCR) for the detection of H pylori infection in comparison with histology and gastric antral biopsy PCR in patients on a proton pump inhibitor (PPI). METHODS: Eighty-five consecutive patients with dyspeptic symptoms were enrolled. Gastric biopsies for histology, PCR and gastric juice were collected at endoscopy for PCR of the H pylori urease C gene (ure C). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, positive and negative likelihood ratio for PCR of gastric juice for the H pylori ure C gene was compared to histology and gastric antral biopsy H pylori ure C PCR in patients with and without PPI. RESULTS: Gastric juice PCR was positive in 66 (78%) patients. Histology showed H pylori associated gastritis in 57 (67%). Gastric biopsy PCR was positive in 72 (85%). In patients not taking PPI, the sensitivity, specificity, PPV, NPV, accuracy and positive and negative likelihood ratio for gastric juice PCR were 89%, 72%, 91%, 67%, 90%, 85%, 3.1 and 0.1 respectively. In patients on PPI these values were 86%, 100%%, 100%, 29%, 86%, 9.5 and 1.4, respectively. CONCLUSION: Gastric juice PCR for the diagnosis of H pylori infection has increased sensitivity compared to histology with PPI. The use of gastric juice PCR is recommended to confirm H pylori status in patients taking PPIs.Javed Yakoob Shahid Rasool Zaigham Abbas Wasim Jafri Shahab Abid Muhammad Islam Zubair Ahmad 2008World Journal of Gastroenterology2008,14,10:4
11Flexible impedance and capacitive tensile load sensor based on CNT composite显示文摘In this paper, the fabrication and investigation of flexible impedance and capacitive tensile load sensors based on carbon nanotube(CNT) composite are reported. On thin rubber substrates, CNTs are deposited from suspension in water and pressed at elevated temperature. It is found that the fabricated load cells are highly sensitive to the applied mechanical force with good repeatability. The increase in impedance of the cells is observed to be 2.0 times while the decrease in the capacitance is found to be 2.1 times as applied force increases up to 0.3 N. The average impedance and capacitive sensitivity of the cell are equal to 3.4 N^(-1) and 1.8 N^(-1), respectively. Experimental results are compared with the simulated values,and they show that they are in reasonable agreement with each other.Zubair Ahmad Kh S Karimov Farid Touati 2016Chinese Physics B2016,25,2:3
12Decorin treatment for reversing trabecular meshwork fibrosis in open-angle glaucoma显示文摘In this perspective,we discuss the use of an anti-fibrotic agent Decorin to treat established fibrosis associated with glaucoma originally published by Hill et al.(2015).Glaucoma describes a group of progressive optic neuropathies that have the potential to cause irreversible blindness,forLisa J Hill Zubair Ahmed Ann Logan 2016Neural Regeneration Research2016,11,6:3
13Optical spin-symmetry breaking for high-efficiency directional helicity-multiplexed metaholograms显示文摘Helicity-multiplexed metasurfaces based on symmetric spin–orbit interactions (SOIs) have practical limits because they cannot provide central-symmetric holographic imaging. Asymmetric SOIs can effectively address such limitations, with several exciting applications in various fields ranging from asymmetric data inscription in communications to dual side displays in smart mobile devices. Low-loss dielectric materials provide an excellent platform for realizing such exotic phenomena efficiently. In this paper, we demonstrate an asymmetric SOI-dependent transmission-type metasurface in the visible domain using hydrogenated amorphous silicon (a-Si:H) nanoresonators. The proposed design approach is equipped with an additional degree of freedom in designing bi-directional helicity-multiplexed metasurfaces by breaking the conventional limit imposed by the symmetric SOI in half employment of metasurfaces for one circular handedness. Two on-axis, distinct wavefronts are produced with high transmission efficiencies, demonstrating the concept of asymmetric wavefront generation in two antiparallel directions. Additionally, the CMOS compatibility of a-Si:H makes it a cost-effective alternative to gallium nitride (GaN) and titanium dioxide (TiO2) for visible light. The cost-effective fabrication and simplicity of the proposed design technique provide an excellent candidate for high-efficiency, multifunctional, and chip-integrated demonstration of various phenomena.Muhammad Ashar Naveed Muhammad Afnan Ansari Inki Kim Trevon Badloe Joohoon Kim Dong Kyo Oh Kashif Riaz Tauseef Tauqeer Usman Younis Murtaza Saleem Muhammad Sabieh Anwar Muhammad Zubair Muhammad Qasim Mehmood Junsuk Rho 2021Microsystems & Nanoengineering2021,7,2:3
14Wolbachia pipientis:A potential candidate for combating and eradicating dengue epidemics in Pakistan显示文摘Dengue virus syndrome is an emerging global health challenge which is endemic in tropical countries like Pakistan.In recent years dengue incidences have increased considerably in different areas of Pakistan with more sever impacts on urban and peri-urban populations.This review is an effort to highlight the changing epidemiology of dengue fever,role of Government of Pakistan in disease management and control using preventive and community based approaches in the region.Moreover,there is an emphasis on application of Wolbachia as novel,inexpeasive and environmentally benign candidate for control and eradication of dengue transmitting vectors.Uruj Tahir Umair Hassan Khan Muhammad Saad Zubair Bahar-e-Mustafa 2015Asian Pacific Journal of Tropical Medicine2015,8,12:2
15Magnetic nanoparticle-based cancer therapy显示文摘Nanoparticles(NPs) with easily modified surfaces have been playing an important role in biomedicine.As cancer is one of the major causes of death,tremendous efforts have been devoted to advance the methods of cancer diagnosis and therapy.Recently,magnetic nanoparticles(MNPs) that are responsive to a magnetic field have shown great promise in cancer therapy.Compared with traditional cancer therapy,magnetic field triggered therapeutic approaches can treat cancer in an unconventional but more effective and safer way.In this review,we will discuss the recent progress in cancer therapies based on MNPs,mainly including magnetic hyperthermia,magnetic specific targeting,magnetically controlled drug delivery,magnetofection,and magnetic switches for controlling cell fate.Some recently developed strategies such as magnetic resonance imaging(MRI) monitoring cancer therapy and magnetic tissue engineering are also addressed.余靓 黄冬雁 Muhammad Zubair Yousaf 侯仰龙 高松 2013Chinese Physics B2013,22,2:2
16Sensitivity enhancement of OD-and OD-CNT-based humidity sensors by high gravity thin film deposition technique显示文摘The humidity sensing properties of the thin films of an organic semiconductor material orange dye(OD)and its composite with CNTs deposited at high gravity conditions have been reported. Impedance, phase angle, capacitance and dissipation of the samples were measured at 1 kHz and room temperature conditions. The impedance decreases and capacitance increases with an increase in the humidity level. It was found that the sensitivity of the OD-based thin film samples deposited at high gravity condition is higher than the samples deposited at low gravity condition. The impedances and capacitance sensitivities of the of the samples deposited under high gravity condition are 6.1 times and 1.6 times higher than the films deposited under low gravity condition.Kh.S.Karimov Noshin Fatima Khaulah Sulaiman M.Mahroof Tahir Zubair Ahmad A.Mateen 2015Journal of Semiconductors2015,36,3:2
17The potential of solar-driven humidification–dehumidification desalination for small-scale decentralized water production显示文摘G. Prakash Narayan Mostafa H. Sharqawy Edward K. Summers John H. Lienhard Syed M. Zubair M.A. Antar 2009Renewable and Sustainable Energy Reviews2009,,4:2
18Advances in engineered Bacillus subtilis biofilms and spores, and their applications in bioremediation, biocatalysis, and biomaterials显示文摘Bacillus subtilis is a commonly used commercial specie with broad applications in the fields of bioengineering and biotechnology.B.subtilis is capable of producing both biofilms and spores.Biofilms are matrix-encased multicellular communities that comprise various components including exopolysaccharides,proteins,extracellular DNA,and poly-γ-glutamic acid.These biofilms resist environmental conditions such as oxidative stress and hence have applications in bioremediation technologies.Furthermore,biofilms and spores can be engineered through biotechnological techniques for environmentally-friendly and safe production of bio-products such as enzymes.The ability to withstand with harsh conditions and producing spores makes Bacillus a suitable candidate for surface display technology.In recent years,the spores of such specie are widely used as it is generally regarded as safe to use.Advances in synthetic biology have enabled the reprogramming of biofilms to improve their functions and enhance the production of value-added products.Globally,there is increased interest in the production of engineered biosensors,biocatalysts,and biomaterials.The elastic modulus and gel properties of B.subtilis biofilms have been utilized to develop living materials.This review outlines the formation of B.subtilis biofilms and spores.Biotechnological engineering processes and their increasing application in bioremediation and biocatalysis,as well as the future directions of B.subtilis biofilm engineering,are discussed.Furthermore,the ability of B.subtilis biofilms and spores to fabricate functional living materials with self-regenerating,self-regulating and environmentally responsive characteristics has been summarized.This review aims to resume advances in biological engineering of B.subtilis biofilms and spores and their applications.Muhammad Zubair Mohsin Rabia Omer Jiaofang Huang Ali Mohsin Meijin Guo Jiangchao Qian Yingping Zhuang 2021Synthetic and Systems Biotechnology2021,6,3:2
19Ultrafast low-pump fluence all-optical modulation based on graphene-metal hybrid metasurfaces显示文摘Graphene is an attractive material for all-optical modulation because of its ultrafast optical response and broad spectral coverage.However,all-optical graphene modulators reported so far require high pump fluence due to the ultrashort photo-carrier lifetime and limited absorption in graphene.We present modulator designs based on graphene-metal hybrid plasmonic metasurfaces with highly enhanced light-graphene interaction in the nanoscale hot spots at pump and probe(signal)wavelengths.Based on this design concept,we have demonstrated high-speed all-optical modulators at near and mid-infrared wavelengths(1.56μm and above 6μm)with significantly reduced pump fluence(1–2 orders of magnitude)and enhanced optical modulation.Ultrafast near-infrared pump-probe measurement results suggest that the modulators’response times are ultimately determined by graphene’s ultrafast photocarrier relaxation times on the picosecond scale.The proposed designs hold the promise to address the challenges in the realization of ultrafast all-optical modulators for mid-and far-infrared wavelengths.Ali Basiri Md Zubair Ebne Rafique Jing Bai Shinhyuk Choi Yu Yao 2022Light(Science & Applications)2022,11,5:2
20The Determinants of Chinese Outward Foreign Direct Investment:A Closer Look显示文摘Over the last fifteen years,China rapidly expanded its outward foreign direct investment (OFDI)through remarkable economic growth and the 'go global'policy.Chinese firms explored investment avenues especially in developing and emerging countries.As a result,China became the third largest contributor of OFDI.We examine the determinants of Chinese OFDI in 67 countries during the period lasting from 2006 to 2015 using the feasible generalized least square method.We find that the size of the economy,market opportunities,cost advantages due to low wage structure,ease of doing business, country risk,and geographical proximity are the prominent factors leading to changes in Chinese OFDI in developing and emerging economies.We find that China's investments in different developing and emerging countries are driven by a different set of factors and the determinants of Chinese OFDI vary in low and high per capita income countries.Muhammad Zubair Mumtaz Zachary Alexander Smith 2018Frontiers of Economics in China-Selected Publications from Chinese Universities2018,13,4:2
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