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| 1 | Hypoalbuminemia in colorectal cancer prognosis:Nutritional marker or inflammatory surrogate?显示文摘Albumin is the single most abundant protein in the human serum. Its roles in physiology and pathology are diverse. Serum albumin levels have been classically thought to reflect the nutritional status of patients. This concept has been challenged in the last two decades as multiple factors, such as inflammation, appeared to affect albumin levels independent of nutrition. In general, cancer patients have a high prevalence of hypoalbuminemia. As such, the role of hypoalbuminemia in patients with colorectal cancer has received significant interest. We reviewed the English literature on the prognostic value of pretreatment albumin levels in colorectal cancer. We also consolidated the evidence that led to the current understanding of hypoalbuminemia as an inflammatory marker rather than as a nutritional one among patients with colorectal cancer. | Bassel Nazha Elias Moussaly Mazen Zaarour Chanudi Weerasinghe Basem Azab | 2015 | World Journal of Gastrointestinal Surgery2015,7,12: | 22 |
| 2 | Is toxoplasmosis a potential risk factor for liver cirrhosis?显示文摘Objective:To document Toxoplasma gondii(T.gondii) antibody status in patients with liver disease,blood samples were taken from 180 hepatic patients and 180 healthy controls.Methods:Toxoplasma IgG antibody was detected using enzyme-linked immunosorbent assay and histopathological assessment of liver biopsy METAVIR score was applied.Results:Anti-T.gondii IgG antibodies were found in 32.8%of patients and in 22.2%of controls(P=0.02).Toxoplasma seropositivity was significantly associated with lymphadenopathy,history of blood transfusion and reflex impairment in patients.Chronic hepatitis C virus(HCV)and chronic HCV-related cirrhosis groups compared to chronic HBV and chronic HBV-related cirrhosis groups expressed significantly higher prevalence of T.gondii seropositivity(odds ratio(OR) =4;95%confidence interval(CI):1.3-12.6;P=0.013,OR=4.8;95%CI:1.5-14.9;P=0.006,respectively).Within the chronic HCV group,T.gondii seropositivity significantly associated disease evolution as regards to METAVIR histopathological system for fibrosis and inflammation(OR=19.4;95%CI:2.3-165.2;P=0.0008,OR=0.29;95%CI:0.1-0.8;P=0.01,respectively).Albumin,international normalized ratio(INR) and platelets count were the laboratory parameters significantly altered in Toxoplasma-positrvc chronic HCV patients(P=0.00 l,0.03,0.04,respectively).Child-Pugh scoring for cirrhosis in chronic HCV group placed the majority of seropositive patient in class C with significant statistical difference compared to Child A reference group(OR= 0.08;95%67:0.01-0.5;P=0.003).Conclusions:Toxoplasma seropositivity was high in patients with cirrhosis and associated higher grades of inflammation and necrosis signifying disease evolution,suggesting that cirrhotic patients may thus form a risk group for toxoplasmosis. | Abeer Abd El-Rehim El-Henawy Ahmed Abdel-Razik Sahar Zakaria Dina Elhammady Niveen Saudy Manar Sobh Azab | 2015 | Asian Pacific Journal of Tropical Medicine2015,8,10: | 4 |
| 3 | High performance decoupled active and reactive power control for three-phase grid-tied inverters using model predictive control显示文摘Finite control set-model predictive control (FCS-MPC) is employed in this paper to control the operation of a three-phase grid-connected string inverter based on a direct PQ control scheme. The main objective is to achieve high-performance decoupled control of the active and reactive powers injected to the grid from distributed energy resources (DER).The FCS-MPC scheme instantaneously searches for and applies the optimum inverter switching state that can achieve certain goals, such as minimum deviation between reference and actual power;so that both power components (P and Q) are well controlled to their reference values.In addition, an effective method to attenuate undesired cross coupling between the P and Q control loops, which occurs only during transient operation, is investigated. The proposed method is based on the variation of the weight factors of the terms of the FCS-MPC cost function, so a higher weight factor is assigned to the cost function term that is exposed to greater disturbance. Empirical formulae of optimum weight factors as functions of the reference active and reactive power signals are proposed and mathematically derived. The investigated FCS-MPC control scheme is incorporated with the LVRT function to support the grid voltage in fulfilling and accomplishing the up-to-date grid codes. The LVRT algorithm is based on a modification of the references of active and reactive powers as functions of the instantaneous grid voltage such that suitable values of P and Q are injected to the grid during voltage sag.The performance of the elaborated FCS-MPC PQ scheme is studied under various operating scenarios, including steady-state and transient conditions. Results demonstrate the validity and effectiveness of the proposed scheme with regard to the achievement of high-performance operation and quick response of grid-tied inverters during normal and fault modes. | Mohamed Azab | 2021 | Protection and Control of Modern Power Systems2021,6,1: | 3 |
| 4 | Neuroinflammation and subarachnoid hemorrhage: a revised look at the literature显示文摘A key topic for aneurysmal subarachnoid hemorrhage is neuroinflammation.Neuroinflammation can predispose to aneurysm formation and rupture.Neuroinflammation can also result from the blood breakdown products after aneurysm rupture.Recent evidence has shown that perpetual neuroinflammation can contribute to vasospasm and hydrocephalus.Targeting neuroinflammation is a novel mechanism for preventing subsequent neurologic sequalae.In this review,we highlight the pathophysiology of aneurysm formation,the neuroinflammatory surge after rupture including the involved cytokines,and ultimately tie in the contributory clinical relevance.In the last sections,we look at the pre-clinical data and novel avenues for further discovery.This paper will be a useful resource to both the clinician and scientific investigator. | Sai Sriram Christopher Cutler Mohammed Azab Ramya Reddy Rodeania Peart Brandon Lucke-Wold | 2022 | Clinical Research Communications2022,5,3: | 2 |
| 5 | Laboratory-based surveillance of patients with bacterial meningitis in Egypt (1998 - 2004) 显示文摘 | Afifi S Wasfy M O Azab M A | 2007 | Eur J Clin Microbiol Infect Dis2007,26,5: | 1 |
| 6 | Usefulness of neutrophil to lymphocyte ratioin predicting short- and long-term mortality after non-ST-elevation myocardialinfarclion显示文摘 | Azab B Zaher M Weiserbs KF | 2010 | Am J Cardiol2010,106,4: | 1 |
| 7 | Mcl-1 for the therapy of cancer 显示文摘 | Quinn BA Dash R Azab B eta/ | 2011 | Expert Opin Investig Drugs2011,20,10: | 1 |
| 8 | Surgical management of anterior chamber epithelial cysts显示文摘 | Haller JA Stark WJ Azab A | | 0,,: | 1 |
| 9 | Usefulness of the neutrophil-tolymp- hocyte ratio in predicting short and long-term mortality in breast cancer patients 显示文摘 | Azab B Bhatt VR Phookan J | 2012 | Ann Surg Oncol2012,19,1: | 1 |
| 10 | Targeting breast cancer-initiating/stem cells with melanoma dif- ferentiation-associated gene-7/interleukin-24显示文摘 | BHUTIA S K DAS S K AZAB B | 2013 | Int J Cancer2013,133,: | 1 |
| 11 | MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma显示文摘 | Das SK Bhutia SK Azab B | 2013 | Cancer Res2013,73,2: | 1 |
| 12 | Accuracy of the Justy H Apex locator in determining working length in simulated horizontal and vertical fractures 显示文摘 | Azabal M Garcia-Otero D de la Macorra J C | 2004 | Int Endod J2004,37,3: | 1 |
| 13 | Usefulness of neutrophil to lymphocyte ratio in predicting short- and long-term mortality after aon-ST-elevation myocardial infarction 显示文摘 | Azab B Zaher M Weiserbs KF | 2010 | Am J Cardiol2010,106,4: | 1 |
| 14 | The prevalenceandriskfactors of urinary incontinence and its influence on the quality of life among egyptian women 显示文摘 | El- Azab AS Mohamed EM Sabra HI | 2007 | Neurourol Urodyn2007,26,6: | 1 |
| 15 | Usefulness of red cell distribution width in predicting all-cause long-term mortality after non-ST-elevation myocardial infarction显示文摘 | Azab B Torbey E Hatoum H | 2011 | Cardiology2011,119,2: | 1 |
| 16 | Cell trafficking of en- dothelial progenitor cells in tumor progression 显示文摘 | de la Puente P Muz B Azab F | 2013 | Chn Cancer Res2013,19,13: | 1 |
| 17 | Accuracy of the Justy Ⅱ Apex locator in determining working length in simulated horizontal and vertical fractures显示文摘 | Azabal M Garcia-Otero D de la Macorra JC | 2004 | Int Endod J2004,37,3: | 1 |
| 18 | Neutrophil - lymphocyte ra- tio as a predictor of adverse outcomes of acute pancreatitis 显示文摘 | Azab B Jaglall N Atallah JP | 2011 | Pancreatology2011,11,4: | 1 |
| 19 | Monotonic properties of unidirec-tional glass fiber (U)/random glass fiber (R)/epoxy hybrid com- posites显示文摘 | Selmy AI Elsesi AR Azab NA | 2011 | Mater Des2011,,32: | 1 |
| 20 | Partial ureteric obstruction : a study of Doppler ultrasonography and diuretic renography in different grade and duration 显示文摘 | Shokier A A Nijman R J Azab M | 1996 | Br J Urol1996,78,6: | 1 |