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| 1 | Evaluation of protective effect of cactus pear seed oil(Opuntia ficusincida L. MILL.) against alloxan-induced diabetes in mice显示文摘Objective: To evaluate the in vitro antioxidant power of cactus pear seed oil [Opuntia ficusincida L. MILL.(CPSO)] and its protective effect against chemically induced diabetes mellitus in mice. Methods: The in vitro antioxidant effect of CPSO was evaluated using 2,2-diphenyl-1-picrylhydrazyl(DPPH) scavenging assay. The preventive effect was conducted on Swiss albino mice treated with CPSO(2 m L/kg, per os), before and after a single intraperitoneal alloxan administration(100 mg/kg). Survival rate, body weight and fasting blood glucose were measured and histopathological analysis of pancreas was performed to evaluate alloxaninduced tissue injuries. Results: CPSO exhibited an antioxidant effect in DPPH scavenging assay. Moreover, the administration of CPSO(2 m L/kg) significantly attenuated alloxaninduced death and hyperglycemia(P<0.001) in treated mice. Morphometric study of pancreas revealed that CPSO significantly protected islets of langerhans against alloxan induced-tissue alterations. Conclusions: Based on theses results, CPSO can prevent alloxan-induced-diabetes by quenching free radicals produced by alloxan and inhibiting tissue injuries in pancreatic β-cells. | Berraaouan Ali Ziyyat Abderrahim Mekhfi Hassane Legssyer Abdelkhaleq Aziz Mohammed Bnouham Mohamed | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，7： | 6 |
| 2 | Micro RNAs and clinical implications in hepatocellular carcinoma显示文摘AIM To assess the role of some circulating miRNAs(miR-23a, miR-203, miR338, miR-34, and miR-16) as tumor markers for diagnosis of hepatocellular carcinoma(HCC).METHODS One hundred and seventy-one subjects were enrolled, 57 patients with HCC, 57 patients with liver cirrhosis(LC) and 57 healthy subjects as control group. Severity of liver disease was assessed by Child Pugh score. Tumor staging was done using Okuda staging system. Quantification of Micro RNA(miR-23a, miR-203, miR338, miR-34, and miR-16) was performed.RESULTS All studied miRNA showed significant difference between HCC and cirrhotic patients in comparison tohealthy control. miR-23a showed statistically significant difference between HCC and cirrhotic patients being higher in HCC group than cirrhotic. miR-23a is significantly higher in HCC patients with focal lesion size equal or more than 5cm, patients with multiple focal lesions and Okuda stage Ⅲ. At cutoff value ≥ 210, miR-23a showed accuracy 79.3% to diagnose HCC patients with sensitivity 89.47% and specificity about 64.91%. At cut off level ≥ 200 ng/mL, serum alpha fetoprotein had 73.68% sensitivity, 52.63% specificity, 43.75% PPV, 80% NPV for diagnosis of HCC.CONCLUSION MicroR NA 23a can be used as a screening test for early detection of HCC. Also, it is related to larger size of tumour, late Okuda staging and multiple hepatic focal lesions, so it might be a prognostic biomarker. | Amal Ahmed Mohamed Zainab A Ali-Eldin Tamer A Elbedewy Magdy El-Serafy Fatma A Ali-Eldin Hossameldin Abdel Aziz | 2017 | World Journal of Hepatology2017，9，23： | 4 |
| 3 | Media effects on the dynamics of a stochastic SIRI epidemic model with relapse and Lévy noise perturbation显示文摘In this paper, we study the dynamic properties of an SIRI epidemic model incorporating media coverage, and stochastically perturbed by a Lévy noise. We establish the existence of a unique global positive solution. We investigate the dynamic properties of the solution around both disease-free and endemic equilibria points of the deterministic model depending on the basic reproduction number under some noise excitation. Furthermore, we present some numerical simulations to support the theoretical results. | Badr-Eddine Berrhazi Mohamed El Fatini Roger Pettersson Aziz Laaribi | 2019 | International Journal of Biomathematics2019，12，3： | 4 |
| 4 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 5 | Short‐term evaluation of autologous transplantation of bone marrow–derived mesenchymal stem cells in patients with cirrhosis: Egyptian study显示文摘 | Mona A. Amin Dina Sabry Laila A. Rashed Wael M. Aref Mohamed Ahmed el‐Ghobary Marwa Salah Farhan Hany Ahmed Fouad Youssef Abdel‐Aziz Youssef | 2013 | Clin Transplant2013，，4： | 2 |
| 6 | 用于制备优质单壁碳纳米管管束的MgO负载Fe_3O_4纳米粒子的合成(英文)显示文摘采用沉淀方法制备了直径分布狭窄的均匀Fe3O4纳米颗粒。Fe3O4纳粒形体几近一致,平均粒径为10.33nm±2.99nm(平均粒径±标准偏差)。在超声作用下将MgO纳米颗粒分散在一定量Fe3O4纳米颗粒的水溶液中获得MgO负载Fe3O4的纳米颗粒。以甲烷为碳源,Fe3O4/MgO为催化剂,经化学气相沉积,在Fe3O4纳粒上制得了大量直径近乎均匀的单壁碳纳米管(SWCNTs)束。TEM显示:SWCNTs的平均直径1.22nm。热重分析显示:样品在400℃~600℃温度区间失重量约19%。拉曼光谱显示:SWCNTs的ID/IG的强度比为0.03,表明采用Fe3O4/MgO催化剂可制得高石墨化程度的单壁碳纳米管。 | Wei-Wen Liu Azizan Aziz Siang-Piao Chai Abdul Rahman Mohamed Ching-Thian Tye | 2011 | 新型炭材料2011，26，4： | 2 |
| 7 | Geo-political Approach: Leviathan and Gaza Marine Gas -Israel and Turkey Are Major Players in the Energy Market显示文摘 | Mohamed Aziz Abdel-Hassan | 2018 | Journal of US-China Public Administration2018，15，1： | 2 |
| 8 | Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression显示文摘BACKGROUND The histopathological findings on the failing kidney allograft in the modern era is not well studied. In this study, we present our experience working with kidney transplant recipients with graft failure within one year of the biopsy.AIM To report the histopathological characteristics of failed kidney allografts in the current era of immunosuppression based on the time after transplant, cause of the end-stage renal disease and induction immunosuppressive medications.METHODS In a single-center observational study, we characterized the histopathological findings of allograft biopsies in kidney transplant recipients with graft failure within one year after the biopsy.RESULTS We identified 329 patients with graft failure that met the selection criteria between January 1, 2006 and December 31, 2016. The three most common biopsy findings were interstitial fibrosis and tubular atrophy(IFTA, 53%), acute rejection (AR, 43%) and transplant glomerulopathy(TG, 33%). Similarly, the three most common causes of graft failure based on the primary diagnosis were AR(40%),TG(17%), and IFTA(13%). Most grafts failed within two years of post-transplant(36%). Subsequently, approximately 10%-15% of grafts failed every two years: >2-4 years(16%), > 4-6 years(13%), > 6-8 years(11%), > 8-10 years(9%) and > 10 years(16%). AR was the most common cause of graft failure in the first six years(48%), whereas TG was the most prevalent cause of graft failure after 6 years(32%) of transplant.CONCLUSION In the current era of immunosuppression, AR is still the most common cause of early graft failure, while TG is the most prevalent cause of late graft failure. | Sandesh Parajuli Fahad Aziz Neetika Garg Sarah E Panzer Emily Joachim Brenda Muth Maha Mohamed Justin Blazel Weixiong Zhong Brad C Astor Didier A Mandelbrot Arjang Djamali | 2019 | World Journal of Transplantation2019，9，6： | 2 |
| 9 | Hemisynthesis of all the O-monomethylated analogues of quercetin including the major metabolites, through selective pro-tection of phenolic functions 显示文摘 | Mohamed B Stephane L Aziz A | 2002 | Tetrahedron2002，58，10： | 1 |
| 10 | Hemisynthesis of all the O-monomethylated analogues of quercetin including the major metabolites, through selective protection of phenolic functions 显示文摘 | Mohamed B Stephane L Aziz A | 2002 | Tetrahedron2002，58，10： | 1 |
| 11 | Amblyopia screening for first and second-grade children in Jordan显示文摘AIM:To share the results of a national screening program for amblyopia in school children in the north of Jordan.METHODS:This is a prospective national screening study for amblyopia.The program rolls first and second-grade children(6 to 7 years old) in the north of Jordan.The eye examination included:best-corrected visual acuity,cover-uncover test,and cycloplegic retinoscopy.Monocular visual acuity was tested using an ETDRS visual acuity chart without correction.Moreover,children were tested with full cycloplegic refraction when the test criteria were met.Unilateral amblyopia was defined as a best-corrected visual acuity difference of 2 or more lines.In comparison,bilateral amblyopia was defined as a best-corrected visual acuity of 20/40 or worse in the best eye.RESULTS:The prevalence of amblyopia for the total sample tested(n=17 203) was 2.78%(n=479).The most common cause of amblyopia was hypermetropia(64.45%),followed by previous ocular surgeries(15.1%),myopia(10.43%),strabismus(9.39%),and congenital cataract(0.63%).CONCLUSION:This is the first and only study,identifing modifiable risk factors in Jordanian children with amblyopia.In their first couple of years of elementary education,many Jordanian children are affected by amblyopia and pass unnoticed.A more governmental effort is needed into screening programs to improve vision in the Jordanian population. | Khalil M.Al-Salem Mohammad S.Saleem Ismat Ereifej Hamzeh M.Alrawashdeh Rayed Falah Hussein Obeidat Asma Ali Abdlmohdi Raeda Zaki Al-Momani Layal Mohammed Hammad Omar Ahmad al-Habahbeh Yaqeen M.Assassfeh Laith Ramzi Najib Al-Qsous Ashraf Hatim Adeeb Nasraween Tariq A.Al Maaitah Deya'-Aldin Muneer Hasan Aqeel Ibtehal Eyadeh Awad Alabdulrazzg Abdullah Mahmoud Mohammad Murad Amany Jehad Faleh AL-Zurqan Enas Jamal Mohammad Jaradat Slsabela Emad Suliman Aldhoon Ala'a Majed Dmour Ahmad Talal Asassfeh Jeries Ayman Halaseh Abdel Aziz Ammar Daoud Waha Ayman Alkasasbeh Kholoud GH.Matar | 2022 | International Journal of Ophthalmology(English edition)2022，15，2： | 1 |
| 12 | A prospective randomized trial of sham, single-dose Stretta, and double-dose Stretta for the treatment of gastroesophageal reflux disease显示文摘 | Ayman M. Abdel Aziz Hisham R. El-Khayat Ahmed Sadek Samer G. Mattar Gail McNulty Pradermchai Kongkam Mohamed F. Guda Glen A. Lehman | 2010 | Surgical Endoscopy2010，，4： | 1 |
| 13 | Gemcitabine plus oxaliplatin in advanced hepatocellular carcinoma: A large multicenter AGEO study显示文摘 | Aziz Zaanan Nicolas Williet Mohamed Hebbar Tienhan Sandrine Dabakuyo Laetitia Fartoux Touraj Mansourbakht Olivier Dubreuil Olivier Rosmorduc Stéphane Cattan Franck Bonnetain Valérie Boige Julien Ta?eb | 2013 | Journal of Hepatology2013，，1： | 1 |
| 14 | Physico-chemical method for ammonia removal from synthetic waste water using limestone and GAC in batch and column studies显示文摘 | Sabir Hussain Hamidi Abdul Aziz Mohamed Hasnain Isa | | 0，，01： | 1 |
| 15 | Hepatoprotective effect of Opuntia dillenii seed oil on CCl_4 induced acute liver damage in rat显示文摘Objective:To investigate the hepatoprotective effect of Opuntia dillenii seed oil(ODSO)on CCl_4 provoked liver injury in rat.Methods:Animals were treated orally with ODSO at a concentration of 2 mL/kg,once daily for one week before the first intraperitoneal injection of CCl_4,and thereafter the administration of the oil was continued for 7 days until the introduction of the second injection of CCl_4.Fourteen hours after the last dose of CCl_4,rats were sacrificed,and the relative liver weight,weight gain,alkaline phosphatase,aspartate amino transferase,alanine aminotransferase,direct bilirubin,total bilirubin,triglycerides,total cholesterol,very low density lipoprotein,low density lipoprotein,high density lipoprotein,plasmatic glucose,urea,creatinine,acid uric and malondialdehyde were determined.Results:The significant increase was found in relative liver weight and plasma levels of alanine aminotransferase,aspartate amino transferase,alkaline phosphatase,total bilirubin,direct bilirubin,triglycerides,very low-density lipoprotein,urea,uric acid and malondialdehyde.Likewise,the significant decrease was indicated in the weight gain and the level of glucose plasmatic,and high-density lipoprotein levels in CCl_4 produced liver injury in rats were re-established to normal levels when treated with ODSO.While,no change was observed in the total cholesterol,low-density lipoprotein and creatinine in all animals.Conclusions:We conclude that the ODSO has a protective effect on CCl_4-mediated liver injury.Hence,we suggest its inclusion as a preventive control of liver disorders. | Mohamed Bouhrim Hayat Ouassou Mohamed Choukri Hassane Mekhfi Abderrahim Ziyyat Abdelkhaleq Legssyer Mohammed Aziz Mohamed Bnouham | 2018 | Asian Pacific Journal of Tropical Biomedicine2018，8，5： | 1 |
| 16 | Central corneal thickness in full‐term Saudi newborns显示文摘 | Adel A. Rushood Mohammed H. Zahrani Ammar Khamis Abdul‐Aziz A. Rushood | 2012 | Acta Ophthalmologica2012，，5： | 1 |
| 17 | Hemisynthesis of all the O-monomethylated analogues of quercetin including the major metabolites, through selective protection of phenolic functions 显示文摘 | Mohamed B Stephane L Aziz A | 2002 | Tetrahedron2002，58，10： | 1 |
| 18 | A statistical experiment design approach for optimizing biodegradation of weathered crude oil in coastal sediments显示文摘 | Leila Mohajeri Hamidi Abdul Aziz Mohamed Hasnain Isa | 2010 | Bioresource Technology2010，101，： | 1 |
| 19 | Sensory aroma from Maillard reaction of individual and combinations of amino acids with glucose in acidic conditions显示文摘 | WONG K H AZIZ S A MOHAMED S | 2008 | International Journal of Food Science and Technology2008，43，： | 1 |
| 20 | A prospective randomized trial of sham, single-dose Stretta, and double-dose Stretta for the treatment of gastroesophageal reflux disease显示文摘 | Ayman M. Abdel Aziz Hisham R. El-Khayat Ahmed Sadek Samer G. Mattar Gail McNulty Pradermchai Kongkam Mohamed F. Guda Glen A. Lehman | 2010 | Surgical Endoscopy2010，，4： | 1 |
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