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| 1 | Imaging and interventions in hilar cholangiocarcinoma: A review显示文摘Hilar cholangiocarcinoma is a common malignant tumor of the biliary tree. It has poor prognosis with very low 5-year survival rates. Various imaging modalities are available for detection and staging of the hilar cholangiocarcinoma. Although ultrasonography is the initial investigation of choice, imaging with contrast enhanced computed tomography scan or magnetic resonance imaging is needed prior to management. Surgery is curative wherever possible. Radiological interventions play a role in operable patients in theform of biliary drainage and/or portal vein embolization. In inoperable cases, palliative interventions include biliary drainage, biliary stenting and intra-biliary palliative treatment techniques. Complete knowledge of application of various imaging modalities available and about the possible radiological interventions is important for a radiologist to play a critical role in appropriate management of such patients.We review the various imaging techniques and appearances of hilar cholangiocarcinoma and the possible radiological interventions. | Kumble Seetharama Madhusudhan Shivanand Gamanagatti Arun Kumar Gupta | 2015 | World Journal of Radiology2015，7，2： | 18 |
| 2 | Diffusion weighted imaging: Technique and applications显示文摘Diffusion weighted imaging(DWI) is a method of signal contrast generation based on the differences in Brownian motion. DWI is a method to evaluate the molecular function and micro-architecture of the human body. DWI signal contrast can be quantified by apparent diffusion coefficient maps and it acts as a tool for treatment respon-se evaluation and assessment of disease progression. Ability to detect and quantify the anisotropy of diffusion leads to a new paradigm called diffusion tensor imaging(DTI). DTI is a tool for assessment of the organs with highly organised fibre structure. DWI forms an integral part of modern state-of-art magnetic resonance imaging and is indispensable in neuroimaging and oncology. DWI is a field that has been undergoing rapid technical evolution and its applications are increasing every day. This review article provides insights in to the evolution of DWI as a new imaging paradigm and provides a summary of current role of DWI in various disease processes. | Vinit Baliyan Chandan J Das Raju Sharma Arun Kumar Gupta | 2016 | World Journal of Radiology2016，8，9： | 18 |
| 3 | Perfusion computed tomography in renal cell carcinoma显示文摘Various imaging modalities are available for the diagnosis, staging and response evaluation of patients with renal cell carcinoma(RCC). While contrast enhanced computed tomography(CT) is used as the standard of imaging for size, morphological evaluation and response assessment in RCC, a new functional imaging technique like perfusion CT(p CT), goes down to the molecular level and provides new perspectives in imaging of RCC. p CT depicts regional tumor perfusion and vascular permeability which are indirect parameters of tumor angiogenesis and thereby provides vital information regarding tumor microenvironment. Also response evaluation using p CT may predate the size criteria used in Response Evaluation Criteria in Solid Tumors, as changes in the perfusion occurs earlier following tissue kinase inhibitors before any actual change in size. This may potentially help in predicting prognosis, better selection of therapy and more accurate and better response evaluation in patients with RCC. This article describes the techniques and role of p CT in staging and response assessment in patients with RCCs. | Chandan J Das Usha Thingujam Ananya Panda Sanjay Sharma Arun Kumar Gupta | 2015 | World Journal of Radiology2015，7，7： | 8 |
| 4 | Radiological interventions in malignant biliary obstruction显示文摘Malignant biliary obstruction is commonly caused by gall bladder carcinoma, cholangiocarcinoma and metastatic nodes. Percutaneous interventions play an important role in managing these patients. Biliary drainage, which forms the major bulk of radiological interventions, can be pal iative in inoperable patients or pre-operative to improve liver function prior to surgery. Other interventions include cholecystostomy and radiofrequency ablation. We present here the indications, contraindications, technique and complications of the radiological interventions performed in patients with malignant biliary obstruction. | Kumble Seetharama Madhusudhan Shivanand Gamanagatti Deep Narayan Srivastava Arun Kumar Gupta | 2016 | World Journal of Radiology2016，8，5： | 2 |
| 5 | Pediatric vs adult pulmonary tuberculosis:A retrospective computed tomography study显示文摘AIM: To compare the manifestations of chest tuberculosis(TB) in pediatric and adult patients based on contrast enhanced computed tomography of chest.METHODS: This was a retrospective study consisting of 152 patients of chest TB including 48 children and 104 adults who had undergone contrast enhanced computed tomography of chest prior to treatment. The patterns and severity of parenchymal, mediastinal and pleural manifestations were analyzed and compared among different age groups.RESULTS: Parenchymal changes observed include consolidation, air space nodules, miliary TB, cavitation, bronchiectasis and fibrosis and these were noted in 60% of children, 71% of adolescents and 76.9% of adults. These changes were more common in right upper lobe in all age groups. There was no significant difference in the frequency of these changes(except nodules) in different age groups. Centrilobular nodules were seen less commonly in children less than 10 years(P = 0.028). Pleural effusion was noted in 28(18.42%) patients and pericardial effusion in 8(5.3%) patients. No significant difference in the serosal involvement is seen among children and adults. Mediastinal adenopathy was seen 70% of children, 76.3% adolescents and 76.9% of adults and paratracheal nodes were seen most frequently. Nodes had similar features(except matting) among all age groups. Matting of nodes was seen more commonly in children(P = 0.014). CONCLUSION: Pediatric chest tuberculosis can have severe parenchymal lesions and nodal involvement similar to adults. The destructive lung changes observed in children needs immediate attention in view of the longer life span they have and hence in formulating optimal treatment strategies. | Prasad Thotton Veedu Ashu Seith Bhalla Sreenivas Vishnubhatla Sushil Kumar Kabra Arundeep Arora Divya Singh Arun Kumar Gupta | 2013 | World Journal of Clinical Pediatrics2013，2，4： | 2 |
| 6 | Experience with hemoadsorption (CytoSorb~?) in the management of septic shock patients显示文摘BACKGROUND Cytokines and inflammatory mediators are the hallmarks of sepsis.Extracorporeal cytokine hemoadsorption devices are the newer clinical support system to overcome the cytokine storm during sepsis.AIM To retrospectively evaluate the clinical outcomes of patients admitted in intensive care unit with septic shock with different etiologies.METHODS The laboratory parameters including biomarkers such as procalcitonin,serum lactate and C-reactive protein;and the hemodynamic parameters;mean arterial pressure,vasopressor doses,sepsis scores,cytokine levels and other vital parameters were evaluated.We evaluated these outcomes among survivors and non-survivors.RESULTS Of 100 patients evaluated,40 patients survived.Post treatment,the vasopressors dosage remarkably decreased though it was not statistically different;34.15%(P=0.0816)for epinephrine,20.5%for norepinephrine(P=0.3099)and 51%(P=0.0678)for vasopressin.In the survivor group,a remarkable reduction of biomarkers levels;procalcitonin(65%,P=0.5859),C-reactive protein(27%,P=0.659),serum lactate(27%,P=0.0159)and bilirubin(43.11%;P=0.0565)were observed from baseline after CytoSorb^® therapy.A significant reduction in inflammatory markers;interleukin 6 and interleukin 10;(87%and 92%,P<0.0001)and in tumour necrosis factor(24%,P=0.0003)was also seen.Overall,28(28%)patients who were given CytoSorb^® therapy less than 48 h after onset of septic shock survived and the maximum duration of stay for 70%of these patients in intensive care unit was less than 15 d.CONCLUSION CytoSorb^® is a safe and well tolerated rescue therapy option in patients with septic shock.However,early(preferably within<48 h after onset of septic shock)initiation could result in better clinical outcomes.Further randomized trials are needed to define the potential benefits of this new treatment modality. | Yatin Mehta Chitra Mehta Ashish Kumar Joby Varghese George Aditi Gupta Saurabh Nanda Gourav Kochhar Arun Raizada | 2020 | World Journal of Critical Care Medicine2020，9，1： | 2 |
| 7 | A two gene – two promoter system for enhanced expression of a restorer gene (barstar) and development of improved fertility restorer lines for hybrid seed production in crop plants显示文摘 | Naveen Chandra Bisht Arun Jagannath Vibha Gupta Pradeep Kumar Burma Deepak Pental | 2004 | Molecular Breeding2004，，2： | 1 |
| 8 | Biodiversity in the barnyard millet ( Echinochloa frumentacea Link, Poaceae) germplasm in India显示文摘 | Arun Gupta Vinay Mahajan Mukesh Kumar H. S. Gupta | 2009 | Genetic Resources and Crop Evolution2009，，6： | 1 |
| 9 | Use of aluminum oxide nanoparticles in wood composites to enhance the heat transfer during hot-pressing显示文摘 | Anuj Kumar Arun Gupta K V Sharma | 2013 | Eur J Wood Prod2013，71，： | 1 |
| 10 | QSAR study of 5-arylidene-2,4-thiazolidinediones as aldose reductase inhibitors显示文摘 | Love Kumar Soni Arun Kumar Gupta S. G. Kaskhedikar | 2008 | Medicinal Chemistry Research (-)2008，，2： | 1 |
| 11 | Influence of cerium on the texture and ductility of magnesium extrusions显示文摘 | Raja K. Mishra Anil K. Gupta P. Rama Rao Anil K. Sachdev Arun M. Kumar Alan A. Luo | 2008 | Scripta Materialia2008，，： | 1 |
| 12 | Radiation-inducible silencing of uPA and uPAR in vitro and in vivo inmeningioma显示文摘 | Venkateswara Rao Gogineni Arun Kumar Nalla Reshu Gupta Bharathi Gorantla Meena Gujrati Dzung Dinh Jasti Rao | 2010 | International Journal of Oncology2010，，4： | 1 |
| 13 | Characterization and Identification of the Sources of Chromium, Zinc, Lead, Cadmium, Nickel, Manganese and Iron in Pm10 Particulates at the Two Sites of Kolkata, India显示文摘 | Kakoli Karar A. K. Gupta Animesh Kumar Arun Kanti Biswas | 2006 | Environmental Monitoring and Assessment (-)2006，，1： | 1 |
| 14 | Synthesis, characterization and application of lignin nanoparticles (LNPs)显示文摘 | GUPTA Arun Kumar MOHANTY Smita NAYAK S K | 2014 | Materials Focus2014，3，： | 1 |
| 15 | Clinical applications of susceptibility weighted MR imaging of the brain – a pictorial review显示文摘 | Bejoy Thomas Sivaraman Somasundaram Krishnamoorthy Thamburaj Chandrasekharan Kesavadas Arun Kumar Gupta Narendra K. Bodhey Tirur Raman Kapilamoorthy | 2008 | Neuroradiology2008，，2： | 1 |
| 16 | MR imaging appearance of insulinoma in an infant显示文摘 | Chandan Jyoti Das Jyotindu Debnath Arun Kumar Gupta Anup Kumar Das | 2007 | Pediatric Radiology2007，，6： | 1 |
| 17 | MRI in central nervous system infections: A simplified patterned approach显示文摘Recognition and characterization of central nervous system infections poses a formidable challenge to the neuro-radiologist.Imaging plays a vital role,the lesions typically being relatively inaccessible to tisue sampling.The results of an accurate diagnosis are endlessly re-warding,given the availability of excellent pharmaco-logical regimen.The availability of numerous magnetic resonance(MR)sequences which provide functional and molecular information is a powerful tool in the hands of the radiologist.However,the plethora of se-quences and the possibilities on each sequence is also intimidating,and often confusing as well as time con-suming.While a large number of reviews have already described in detail the possible imaging findings in each infection,we intend to classify infections based on their imaging characteristics.In this review we describe an algorithm for first classifying the imaging findings into patterns based on basic MR sequences(T1,T2 and enhancement pattern with Gadolinium),and then sub-classify them based on more advanced molecular and functional sequences(Diffusion,Perfusion,Susceptibili-ty imaging,MR Spectroscopy).This patterned approachis intended as a guide to radiologists in-training and in-practice for quickly narrowing their list of differentials when faced with a clinical challenge.The entire content of the article has also been summarised in the form of flow-charts for the purpose of quick reference. | Krithika Rangarajan Chandan J Das Atin Kumar Arun Kumar Gupta | 2014 | World Journal of Radiology2014，6，9： | 1 |
| 18 | The role of 18F-FDG PET/CT in evaluation of early response to neoadjuvant chemotherapy in patients with locally advanced breast cancer显示文摘 | Amandeep Kumar Rakesh Kumar Vathalaru Seenu Sidharatha Datta Gupta Madhavi Chawla Arun Malhotra Sada Nand Mehta | 2009 | European Radiology2009，，6： | 1 |
| 19 | Skeletal dysplasias: A radiographic approach and review of common non-lethal skeletal dysplasias显示文摘Skeletal dysplasias are not uncommon entities and a radiologist is likely to encounter a suspected case of dysplasia in his practice. The correct and early diagnosis of dysplasia is important for management of complications and for future genetic counselling. While there is an exhaustive classification system on dysplasias, it is important to be familiar with the radiological features of common dysplasias. In this article, we enumerate a radiographic approach to skeletal dysplasias, describe the essential as well as differentiating features of common non-lethal skeletal dysplasias and conclude by presenting working algorithms to either definitively diagnose a particular dysplasia or suggest the most likely differential diagnoses to the referring clinician and thus direct further workup of the patient. | Ananya Panda Shivanand Gamanagatti Manisha Jana Arun Kumar Gupta | 2014 | World Journal of Radiology2014，6，10： | 1 |
| 20 | Adult onset moyamoya disease:Institutional experience显示文摘 | Swati Dayanand Chinchure Hima Shriniwas Pendharkar Arun Kumar Gupta | 2011 | Neurology India2011，59，5： | 1 |
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