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| 1 | Colonic ulcerations may predict steroid-refractory course in patients with ipilimumab-mediated enterocolitis显示文摘AIM To investigate management of patients who develop ipilimumab-mediated enterocolitis, including association of endoscopic findings with steroid-refractory symptoms and utility of infliximab as second-line therapy.METHODS We retrospectively reviewed all patients at our centerwith metastatic melanoma who were treated with ipilimumab between March 2011 and May 2014. All patients received a standard regimen of intravenous ipilimumab 3 mg/kg every 3 wk for four doses or until therapy was stopped due to toxicity or disease progression. Basic demographic and clinical data were collected on all patients. For patients who developed grade 2 or worse diarrhea(increase of 4 bowel movements per day), additional data were collected regarding details of gastrointestinal symptoms, endoscopic findings and treatment course. Descriptive statistics were used.RESULTS A total of 114 patients were treated with ipilimumab during the study period and all were included. Sixteen patients(14%) developed ≥ grade 2 diarrhea. All patients were treated with high-dose corticosteroids(1-2 mg/kg prednisone daily or equivalent). Nine of 16 patients(56%) had ongoing diarrhea despite highdose steroids. Steroid-refractory patients received one dose of intravenous infliximab at 5 mg/kg, and all but one had brisk resolution of diarrhea. Fourteen of the patients underwent either colonoscopy or sigmoidoscopy with variable endoscopic findings, ranging from mild erythema to colonic ulcers. Among 8 patients with ulcers demonstrated by sigmoidoscopy or colonoscopy, 7 patients(88%) developed steroidrefractory symptoms requiring infliximab. With a median follow-up of 264 d, no major adverse events associated with prednisone or infliximab were reported.CONCLUSION In patients with ipilimumab-mediated enterocolitis, the presence of colonic ulcers on endoscopy was associated with a steroid-refractory course. | Animesh Jain Evan J Lipson William H Sharfman Steven R Brant Mark G Lazarev | 2017 | World Journal of Gastroenterology2017，23，11： | 8 |
| 2 | Combustion synthesis of Ce^(3+), Eu^(3+) and Dy^(3+) activated NaCaPO_4 phosphors显示文摘The preparation of NaCaPO4 doped with rare earth (RE) ions Ce3+, Eu3+ and Dy3+ by combustion method was described. Under UV excitation (251 nm) of NaCaPO4:Ce3+ showsd emission (367 nm) in UV range. When NaCaPO4:Dy3+ phosphor was excited at 349 nm, the emission spectrum showed intense bands at 482 nm (blue) and 576 nm (yellow). In Eu activated NaCaPO4 phosphor, the emission spectrum showed a dominant peak at 594 nm (orange) while others were at 614 and 621 nm (red) when excited at 393 nm. The prepared phosphor was characterized by X-ray diffraction (XRD), scanning electron microscope (SEM) and photoluminescence (PL) measurement. Thus, the photoluminescence behavior of NaCaPO4:Ce3+ was strongly suggested for scintillator. Likewise, Eu3+ and Dy3+ activated NaCaPO4 phosphors were recommended for near-UV white light-emitting diodes (LEDs). | K N Shinde S J Dhoble Animesh Kumar | 2011 | Journal of Rare Earths2011，29，6： | 7 |
| 3 | Metabolic effects of obesity:A review显示文摘With the many recent advances in the biomedical world,vast changes are taking place in our growing knowledge of the physiological aspects of almost all the tissues and organs of the human body.One of the most prevalent topics of discussion is the question of obesity and its effect on the metabolic changes in the human body.The original classical role of adipose tissue as an energy storage organ has been greatly modified.We now know that it is an endocrine organ,producing adipokines like leptin,adiponectin,visfatin,resistin,apelin,etc,which modulate metabolic processes in the body.Since obesity is associated with an increase in the adipose tissue mass,these hormones may be expected to be produced in increased concentrations and may thus have a significant impact on the macronutrient metabolism.Further,these adipokines may interact with long term energy modulators like insulin.Even though the scientific community has started unravelling the mysteries of the close linkage between obesity,its hormones and their physiological effects,a lot still remains to be discovered.The present discussion makes an attempt to trace the basic modern day concepts of the role of obesity in various metabolic processes. | Parul Singla Animesh Bardoloi Anuj A Parkash | 2010 | World Journal of Diabetes2010，1，3： | 5 |
| 4 | An Experimental Method to Quantify Extractable Amino Acids in Soils from Southeast China显示文摘The extraction and comparison of soil amino acids using different extractants (deionized water, K2SO4 , Na2SO4 , NaCl, KCl) were reported. Results showed that 0.5 mol L-1 K2SO4 with a 5 times extraction was a better method to assess the concentration of extractable amino acids in soils. The total amino acids extracted from soil planted for tea were similar to the total inorganic nitrogen. While they extracted from vegetable soil and paddy soil were much lower than the total inorganic nitrogen. | CHEN Xian-you WU Liang-huan CAO Xiao-chuang Sarkar Animesh ZHU Yuan-hong | 2013 | Journal of Integrative Agriculture2013，12，4： | 4 |
| 5 | Comparative study between wear of uncoated and TiAIN-coated carbide tools in milling of Ti6AI4V显示文摘 | M. S. Uddin Binh Pham Ahmed Sarhan Animesh Basak Alokesh Pramanik | 2017 | Advances in Manufacturing2017，5，1： | 4 |
| 6 | Graphene-wrapped Ag3PO4/LaCO3OH heterostructures for water purification under visible light显示文摘We demonstrated a unique synthesis approach of graphene(GR)-wrapped Ag_3PO_4/LaCO_3OH(APO/LCO)heterostructures by an in-situ wet chemical method. FESEM analysis reveals the formation of rhombic dodecahedrons of APO decorated with LCO and later wrapped with GR flakes. Optical studies shows two absorption edges corresponding to the band gap energies of APO(2.41 eV) and LCO(4.1 eV). Considering the absorption edge of the heterostructures in the visible region, the photocatalytic activities of photocatalysts containing different APO/LCO mass ratios were evaluated by the degradation of MB. GR-decorated composite with 20% LCO(APO/LCO20/GR) exhibited the highest photocatalytic activity for MB degradation, with a rate constant, k of 0.541 min^(-1). The photocatalytic activity of APO/LCO20/GR more greatly enhanced than those of the individual constituents(APO, LCO, APO/LCO20). The enhanced photocatalytic activity of the heterostructure can be attributed to the co-catalytic effect of LCO as well as intriguing physicochemical properties of GR. To understand the enhanced photocatalytic activity of the heterostructures the photocatalytic reaction mechanism is proposed in detail. The recyclability of the APO/LCO/GR composite photocatalyst is further evaluated by reusing the catalyst in replicate photocatalytic experiments which shows consistent photocatalytic activity thereby confirms the stability and reusability of heterostructure photocatalyst. | Santosh S.Patil Mukund G.Mali Animesh Roy Mohaseen S.Tamboli Virendrakumar G.Deonikar Deepak R.Patil Milind V.Kulkarni Salem S.Al-Deyab Sam S.Yoon Sanjay S.Kolekar Bharat B.Kale | 2016 | Journal of Energy Chemistry2016，25，5： | 2 |
| 7 | Management of Complications Associated with Partially Covered Biliary Metal Stents显示文摘 | Henry Ho Anshu Mahajan Sonia Gosain Animesh Jain Andrew Brock Michele E. Rehan Kristi Ellen Vanessa M. Shami Michel Kahaleh | 2010 | Digestive Diseases and Sciences2010，，2： | 2 |
| 8 | 氧化铝(γ-Al2O3)和锶对Al-20Si合金显微组织和力学性能的影响(英文)显示文摘为得到细晶硅,向铸造Al-20Si合金中加入4%(质量分数,下同)γ-Al2O3和0.1%Sr。在铸造过程中,γ-Al2O3的作用是细化初晶硅,其添加量为0.5%~6%,而锶的作用是改性共晶硅,其添加量为0.05%~0.1%。结果表明,当添加4%γ-Al2O3时,初晶硅的平均尺寸为24μm。当添加0.1%Sr时,共晶硅的形状因子约为0.6,平均长度约为1.2μm。热分析发现γ-Al2O3可以作为潜在的异质形核点。而且,与在Al-20Si合金中同时添加P和Sr一样,同时添加γ-Al2O3和Sr不会污染γ-Al2O3颗粒和抑制他们的形核效率。与铸态Al-20Si合金相比,Al-20Si-4γ-Al2O3-0.1%Sr合金的极限抗拉强度提高了20%,伸长率提高了23%。抗拉强度的提高可归因于初晶硅的细化、共晶硅的改性,以及合金中由于共晶转变而析出的α(Al)。 | Mihira ACHARYA Animesh MANDAL | 2019 | Transactions of Nonferrous Metals Society of China2019，29，7： | 2 |
| 9 | Gene expression profile analysis by DNA microarrays:promise and pitfalls显示文摘 | King Hadley CBA Sinha Animesh A | 2001 | Proc Natl Acad Sci USA2001，98，： | 1 |
| 10 | Cytokine network in pemphi- gus vulgaris: an integrated viewpoint显示文摘 | Cerrene N Giordano Animesh A | 2012 | Autoimmunity2012，45，6： | 1 |
| 11 | Imaging in diagnosis and treatment of pulmonary tuberculosis显示文摘 | Animesh Ray | 2015 | Indian Journal of Radiology and Imaging2015，，4： | 1 |
| 12 | Intrusion Detection in Wireless Ad Hoc Networks显示文摘 | Amitabh M Ketan N Animesh P | 2004 | IEEE Wireless Communications2004，，02： | 1 |
| 13 | Reliability Estimation with Time Variant Loads and Resistances显示文摘 | ANIMESH DEY SANKARAN MAHADEVAN | 2000 | Journal of Structural Engineering2000，126，5： | 1 |
| 14 | Synthesis and optical characterization of nanocrystalline NiFe204 structures 显示文摘 | Srivastava M Animesh K Ojha S C | 2009 | J Alloys Compds2009，481，： | 1 |
| 15 | Reliability Estimation with Time-Variant Loads and Resistances显示文摘 | Animesh D and Sankaran M | 2000 | Journal of Structural Engineering ASCE2000，126，5： | 1 |
| 16 | Thresholds of hydrologic flow regime of a river and investigation of climate change impact—the case of the Lower Brahmaputra river Basin显示文摘 | Animesh K. Gain Heiko Apel Fabrice G. Renaud Carlo Giupponi | 2013 | Climatic Change (-)2013，，1： | 1 |
| 17 | Use of a wake-integral method for computational drag analysis显示文摘 | J Mark Janus Animesh Chatterjee | 1996 | AIAA Journal1996，34，1： | 1 |
| 18 | Pavement design with central plant hot-mix recycled asphalt mixes 显示文摘 | ARAVIND K ANIMESH Das | 2007 | Construction and Building Materials2007，21，： | 1 |
| 19 | Electr- onic nose for black tea quality evaluation by an incremental RBF network 显示文摘 | Bipan T Arun J Animesh M | 2009 | Sensors and Actuators B: Chemical2009，138，： | 1 |
| 20 | Nondestructive testing of asphalt pavements for structural condition evaluation: a state of the art显示文摘 | Amit G Animesh D | 2008 | Nondestructive Testing and Evaluation2008，23，2： | 1 |
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