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| 1 | Protective effect of ascorbic acid on cyclophosphamide induced testicular gametogenic and androgenic disorders in male rats显示文摘Aim:To study the detrimental effects of cyclophosphamide on the testicular androgenic and gametogenic activities through endocrine inhibiton and/or induction of oxidative stress in male albino rats and to evaluate the protective effect of ascorbic acid.Methods:The testicular△^5,3β-hydroxysteroid dehydrogenase(HSD),17β-HSD,peroxidase and catalase activities along with the levels of malondialdehyde(MDA)and conjugated dienes in testicular tissue were measured for the evaluation of testicular oxidative stress.The plasma testosterone(T)level was measured by immunoassay7.Various germ cells at stage VⅡof spermatogenic cycle were quantified from testicular stained sections.Results:Cyclophosphamide treatment results in a significant inhibition in the testicular△^5,3β-HSDand17β-HSDactivities,a decrease in plasma T level and a diminution in the coumts of various gern cells,Moreover,this treatment was also associated with a significant inhibition of the peroxidase and catalase activities along with high levels of MDA and conjugated dienes in the testis.All these changes were reversed by ascorbic acid co-administration.Conclusion:Cyclophosphamide treatment at the dosage used caused testicular gametogenic and androgenic disor-ders as well as induced testicular oxidative stress that can be reversed by ascorbic acid co-administration. | Ujjal Baran Das Mousumi Mallick Jogendra Mohan Debnath Debidas Ghosh | 2002 | Asian Journal of Andrology2002，4，3： | 27 |
| 2 | Advances in fabrication of ceramic corundum abrasives based on sol–gel process显示文摘Corundum abrasives with good chemical stability can be fabricated into various free abrasives and bonded abrasive tools that are widely used in the precision machining of various parts.However,these abrasives cannot satisfy the machining requirements of difficult-to-machine materials with high hardness,high strength,and strong wearing resistance.Although superhard abrasives can machine the above-mentioned materials,their dressing and manufacturing costs are high.By contrast,ceramic corundum abrasives fabricated by sol–gel method is a costeffective product between conventional and superhard abrasives.Ceramic corundum abrasives exhibit self-sharpening and high toughness.In this review,the optimization methods of ceramic corundum abrasive properties are introduced from three aspects:precursor synthesis,particle shaping,and sintering.Firstly,the functional mechanism of seeds and additives on the microstructural and mechanical properties of abrasives is analyzed.Specifically,seeds can reduce the phase transition temperature and improve fracture toughness.The grain size and uniformly dense structure can be controlled by applying an appropriate amount of multicomponent additives.Then,the urgent need of engineering application and machinability of special shape ceramic corundum abrasives is reviewed,and three methods of abrasive shaping are summarized.The micromold replication technique is highly advanced and can be used to prepare functional abrasives.Additionally,the influence of a new sintering method,namely,two-step sintering technique,on the microstructural and mechanical performance of ceramic corundum abrasives is summarized.Finally,the challenge and developmental trend of the optimization of ceramic corundum abrasives are prospected. | Baoteng HUANG Changhe LI Yanbin ZHANG Wenfeng DING Min YANG Yuying YANG Han ZHAI Xuefeng XU Dazhong WANG Sujan DEBNATH Muhammad JAMIL Hao Nan Li Hafiz Muhammad ALI Munish Kumar GUPTA Zafar SAID | 2021 | Chinese Journal of Aeronautics2021，34，6： | 11 |
| 3 | Cryogenic minimum quantity lubrication machining: from mechanism to application显示文摘Cutting fluid plays a cooling-lubrication role in the cutting of metal materials.However,the substantial usage of cutting fluid in traditional flood machining seriously pollutes the environment and threatens the health of workers.Environmental machining technologies,such as dry cutting,minimum quantity lubrication(MQL),and cryogenic cooling technology,have been used as substitute for flood machining.However,the insufficient cooling capacity of MQL with normal-temperature compressed gas and the lack of lubricating performance of cryogenic cooling technology limit their industrial application.The technical bottleneck of mechanical-thermal damage of difficult-to-cut materials in aerospace and other fields can be solved by combining cryogenic medium and MQL.The latest progress of cryogenic minimum quantity lubrication(CMQL)technology is reviewed in this paper,and the key scientific issues in the research achievements of CMQL are clarified.First,the application forms and process characteristics of CMQL devices in turning,milling,and grinding are systematically summarized from traditional settings to innovative design.Second,the cooling-lubrication mechanism of CMQL and its influence mechanism on material hardness,cutting force,tool wear,and workpiece surface quality in cutting are extensively revealed.The effects of CMQL are systematically analyzed based on its mechanism and application form.Results show that the application effect of CMQL is better than that of cryogenic technology or MQL alone.Finally,the prospect,which provides basis and support for engineering application and development of CMQL technology,is introduced considering the limitations of CMQL. | Mingzheng LIU Changhe LI Yanbin ZHANG Qinglong AN Min YANG Teng GAO Cong MAO Bo LIU Huajun CAO Xuefeng XU Zafar SAID Sujan DEBNATH Muhammad JAMIL Hafz Muhammad ALI Shubham SHARMA | 2021 | Frontiers of Mechanical Engineering2021，16，4： | 8 |
| 4 | Milling Force Model for Aviation Aluminum Alloy: Academic Insight and Perspective Analysis显示文摘Aluminum alloy is the main structural material of aircraft,launch vehicle,spaceship,and space station and is processed by milling.However,tool wear and vibration are the bottlenecks in the milling process of aviation aluminum alloy.The machining accuracy and surface quality of aluminum alloy milling depend on the cutting parameters,material mechanical properties,machine tools,and other parameters.In particular,milling force is the crucial factor to determine material removal and workpiece surface integrity.However,establishing the prediction model of milling force is important and difficult because milling force is the result of multiparameter coupling of process system.The research progress of cutting force model is reviewed from three modeling methods:empirical model,finite element simulation,and instantaneous milling force model.The problems of cutting force modeling are also determined.In view of these problems,the future work direction is proposed in the following four aspects:(1)high-speed milling is adopted for the thin-walled structure of large aviation with large cutting depth,which easily produces high residual stress.The residual stress should be analyzed under this particular condition.(2)Multiple factors(e.g.,eccentric swing milling parameters,lubrication conditions,tools,tool and workpiece deformation,and size effect)should be considered comprehensively when modeling instantaneous milling forces,especially for micro milling and complex surface machining.(3)The database of milling force model,including the corresponding workpiece materials,working condition,cutting tools(geometric figures and coatings),and other parameters,should be established.(4)The effect of chatter on the prediction accuracy of milling force cannot be ignored in thin-walled workpiece milling.(5)The cutting force of aviation aluminum alloy milling under the condition of minimum quantity lubrication(mql)and nanofluid mql should be predicted. | Zhenjing Duan Changhe Li Wenfeng Ding Yanbin Zhang Min Yang Teng Gao Huajun Cao Xuefeng Xu Dazhong Wang Cong Mao Hao Nan Li Gupta Munish Kumar Zafar Said Sujan Debnath Muhammad Jamil Hafiz Muhammad Ali | 2021 | Chinese Journal of Mechanical Engineering2021，34，1： | 7 |
| 5 | In vitro antioxidant and anti-inflammatory activities of Korean blueberry(Vaccinium corymbosum L.) extracts显示文摘Objective:To investigate in vitro antioxidant and anti-inflammatory activities of Korean blueberry(Vaccinium corymbosum L.).Methods:Total phenolic and flavonoid contents of the Korean blueberry water and ethanol extracts were determined before determining the potential of the extracts as antioxidant.Antioxidant activity of the extracts was determined by following some well established methods for free radical scavenging such as 2,2-diphenyl-picrylhydrazyl hydrate,1,2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonicacid),free radical induced DNA damage,superoxide dismutaselike and catalase assay etc.Furthermore,1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan and nitric oxide assay were performed to determine the anti-inflammatory activity of the extracts.Results:Total phenolic contents were found(115.0±3.0) and(4.2±3.0) mg GAE/100 g fresh mass for both extracts,respectively and flavonoid contents were(1 942.8±7.0) and(1 292.1±6.0) mg CE/100 g fresh mass for water and ethonal extracts,respectively.Both the extracts displayed significant scavenging activity of some radicals such as 2,2-diphenyl-picrylhydrazyl hydrate(IC_(50) at 1.8 mg/mL and 2.05 mg/mL,respectively),l,2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonicacid)(IC_(50) at1.5 mg/mL and 1.6 mg/mL,respectively) and nitrite(IC_(50) at 1.7 mg/mL and 1.5 mg/mL,respectively)etc.The extracts were found to prevent inflammation as well by reducing nitric oxide production and cytotoxicity in cell.Conclusions:The findings suggest that the fresh Korean blueberry could be used as a source of natural antioxidants and anti-inflammatory agents. | Nadira Binte Samad Trishna Debnath Michael Ye Md.Abul Hasnat Beong Ou Lim | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，10： | 6 |
| 6 | All-silicon carrier accumulation modulator based on a lateral metal-oxide-semiconductor capacitor显示文摘In silicon photonics, the carrier depletion scheme has been the most commonly used mechanism for demonstrating high-speed electro-optic modulation. However, in terms of phase modulation efficiency, carrieraccumulation-based devices potentially offer almost an order of magnitude improvement over those based on carrier depletion. Previously reported accumulation modulator designs only considered vertical metal-oxidesemiconductor(MOS) capacitors, which imposes serious restrictions on the design flexibility and integratability with other photonic components. In this work, for the first time to our knowledge, we report experimental demonstration of an all-silicon accumulation phase modulator based on a lateral MOS capacitor. Using a Mach–Zehnder interferometer modulator with a 500-μm-long phase shifter, we demonstrate high-speed modulation up to 25 Gbit∕s with a modulation efficiency(V_πL_π) of 1.53 V·cm. | KAPIL DEBNATH DAVID J.THOMSON WEIWEI ZHANG ALI Z.KHOKHAR CALLUM LITTLEJOHNS JAMES BYERS LORENZO MASTRONARDI MUHAMMAD K.HUSAIN KOUTA IBUKURO FREOERIC Y.GARDES GRAHAM T,REED SHINICHI SAITO | 2018 | Photonics Research2018，6，5： | 6 |
| 7 | Autophagy and Tumorigenesis显示文摘 | Srirupa Roy Jayanta Debnath | 2010 | Seminars in Immunopathology2010，，4： | 3 |
| 8 | Comparative assessment of force,temperature,and wheel wear in sustainable grinding aerospace alloy using biolubricant显示文摘The substitution of biolubricant for mineral cutting fluids in aerospace material grinding is an inevitable development direction,under the requirements of the worldwide carbon emission strategy.However,serious tool wear and workpiece damage in difficult-to-machine material grinding challenges the availability of using biolubricants via minimum quantity lubrication.The primary cause for this condition is the unknown and complex influencing mechanisms of the biolubricant physicochemical properties on grindability.In this review,a comparative assessment of grindability is performed using titanium alloy,nickel-based alloy,and high-strength steel.Firstly,this work considers the physicochemical properties as the main factors,and the antifriction and heat dissipation behaviours of biolubricant in a high temperature and pressure interface are comprehensively analysed.Secondly,the comparative assessment of force,temperature,wheel wear and workpiece surface for titanium alloy,nickel-based alloy,and high-strength steel confirms that biolubricant is a potential replacement of traditional cutting fluids because of its improved lubrication and cooling performance.High-viscosity biolubricant and nano-enhancers with high thermal conductivity are recommended for titanium alloy to solve the burn puzzle of the workpiece.Biolubricant with high viscosity and high fatty acid saturation characteristics should be used to overcome the bottleneck of wheel wear and nickel-based alloy surface burn.The nano-enhancers with high hardness and spherical characteristics are better choices.Furthermore,a different option is available for high-strength steel grinding,which needs low-viscosity biolubricant to address the debris breaking difficulty and wheel clogging.Finally,the current challenges and potential methods are proposed to promote the application of biolubricant. | Xin CUI Changhe LI Yanbin ZHANG Wenfeng DING Qinglong AN Bo LIU Hao Nan LI Zafar SAID Shubham SHARMA Runze LI Sujan DEBNATH | 2023 | Frontiers of Mechanical Engineering2023，18，1： | 3 |
| 9 | ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death显示文摘 | Lilliana Radoshevich Lyndsay Murrow Nan Chen Estefania Fernandez Srirupa Roy Christopher Fung Jayanta Debnath | 2010 | Cell2010，，4： | 3 |
| 10 | Minimum quantity lubrication machining of aeronautical materials using carbon group nanolubricant: From mechanisms to application显示文摘It is an inevitable trend of sustainable manufacturing to replace flood and dry machining with minimum quantity lubrication(MQL)technology.Nevertheless,for aeronautical difficult-tomachine materials,MQL couldn’t meet the high demand of cooling and lubrication due to high heat generation during machining.Nano-biolubricants,especially non-toxic carbon group nano-enhancers(CGNs)are used,can solve this technical bottleneck.However,the machining mechanisms under lubrication of CGNs are unclear at complex interface between tool and workpiece,which characterized by high temperature,pressure,and speed,limited its application in factories and necessitates in-depth understanding.To fill this gap,this study concentrates on the comprehensive quantitative assessment of tribological characteristics based on force,tool wear,chip,and surface integrity in titanium alloy and nickel alloy machining and attempts to answer mechanisms systematically.First,to establish evaluation standard,the cutting mechanisms and performance improvement behavior covering antifriction,antiwear,tool failure,material removal,and surface formation of MQL were revealed.Second,the unique film formation and lubrication behaviors of CGNs in MQL turning,milling,and grinding are concluded.The influence law of molecular structure and micromorphology of CGNs was also answered and optimized options were recommended by considering diverse boundary conditions.Finally,in view of CGNs limitations in MQL,the future development direction is proposed,which needs to be improved in thermal stability of lubricant,activity of CGNs,controllable atomization and transportation methods,and intelligent formation of processing technology solutions. | Xin CUI Changhe LI Wenfeng Ding Yun CHEN Cong MAO Xuefeng XU Bo LIU Dazhong WANG Hao Nan LI Yanbin ZHANG Zafar SAID Sujan DEBNATH Muhammad JAMIL Hafiz Muhammad ALI Shubham SHARMA | 2022 | Chinese Journal of Aeronautics2022，35，11： | 3 |
| 11 | Inference on disk-jet connection of MAXI J1836–194 from spectral analysis with the TCAF solution显示文摘Galactic transient black hole candidate(BHC)MAXI J1836–194 was discovered on 2011 Aug30,by MAXI/GSC and Swift/BAT.The source activity during this outburst continued for^3 months before entering into the quiescent state.It again became active in March 2012 and continued for another^2 months.In this paper,3-25 keV RXTE/PCA spectra from the 2011 outburst and 0.5-10.0 keV Swift/XRT data during its 2012 outburst are analyzed with the two-component advective flow(TCAF)model based fits files in XSPEC.We calculate the X-ray contributions coming from jets/outflow using a newly developed method based on the deviation of the TCAF model normalization.We also study the correlation between observed radio and estimated jet X-ray fluxes.The correlation indices(b)are found to be 1.79 and 0.61,when the 7.45 GHz Very Large Array(VLA)radio flux is correlated with the total X-ray and jet X-ray fluxes in 3-25 keV range respectively.It has been found that the jet contributes in X-rays up to a maximum of 86%during its 2011 outburst.This makes the BHC MAXI J1836–194 strongly jet dominated during the initial rising phase. | Arghajit Jana Dipak Debnath Sandip KChakrabarti Debjit Chatterjee | 2020 | Research in Astronomy and Astrophysics2020，20，3： | 2 |
| 12 | Biological Stability of Water-Based Cutting Fluids:Progress and Application显示文摘The application of cutting fluid in the field of engineering manufacturing has a history of hundreds of years,and it plays a vital role in the processing efficiency and surface quality of parts.Among them,water-based cutting fluid accounts for more than 90%of the consumption of cutting fluid.However,long-term recycling of water-based cutting fluid could easily cause deterioration,and the breeding of bacteria could cause the cutting fluid to fail,increase manufacturing costs,and even endanger the health of workers.Traditional bactericides could improve the biological stability of cutting fluids,but they are toxic to the environment and do not conform to the development trend of low-carbon manufacturing.Low-carbon manufacturing is inevitable and the direction of sustainable manufacturing.The use of nanomaterials,transition metal complexes,and physical sterilization methods on the bacterial cell membrane and genetic material could effectively solve this problem.In this article,the mechanism of action of additives and microbial metabolites was first analyzed.Then,the denaturation mechanism of traditional bactericides on the target protein and the effect of sterilization efficiency were summarized.Further,the mechanism of nanomaterials disrupting cell membrane potential was discussed.The effects of lipophilicity and the atomic number of transition metal complexes on cell membrane penetration were also summarized,and the effects of ultraviolet rays and ozone on the destruction of bacterial genetic material were reviewed.In other words,the bactericidal performance,hazard,degradability,and economics of various sterilization methods were comprehensively evaluated,and the potential development direction of improving the biological stability of cutting fluid was proposed. | Lizhi Tang Yanbin Zhang Changhe Li Zongming Zhou Xiaolin Nie Yun Chen Huajun Cao Bo Liu Naiqing Zhang Zafar Said Sujan Debnath Muhammad Jamil Hafiz Muhammad Ali Shubham Sharma | 2022 | Chinese Journal of Mechanical Engineering2022，35，1： | 2 |
| 13 | In vitro anti- Helicobacter pylori activity of a flavonoid rich extract of Glycyrrhiza glabra and its probable mechanisms of action显示文摘 | Mannanthendil Kumaran Asha Debnath Debraj D’souza Prashanth Jothie Richard Edwin H.S. Srikanth Nithyanantham Muruganantham Shekhar Michael Dethe Bhaskar Anirban Balachandran Jaya Mundkinajeddu Deepak Amit Agarwal | 2012 | Journal of Ethnopharmacology2012，，： | 2 |
| 14 | An improved brain MR image binarization method as a preprocessing for abnormality detection and features extraction显示文摘这份报纸为特征抽取和大脑反常鉴定的预处理的使用建议大脑 binarization 的磁性的回声成像(MRI ) 的一个计算机化的方法。MRI binarization 的主要问题之一是大脑部分的许多象素不能是正确地 binarized 由于在在 MRI 的背景和前景之间的对比的广泛的黑背景或大变化。我们建议了决定阀值价值的使用意味着的 binarization,变化,标准差和熵由罐头克服大脑部件的 binarization 问题的非范围改进列在后面。建议 binarization 技术广泛地与许多 MRI 被测试并且与改进精确性和减少的错误产生好 binarization。比较关于另外的著名方法与这个创新方法在获得的结果之中被执行。 | Sudipta ROY Debnath BHATTACHARYYA Samir Kumar BANDYOPADHYAY Tai-Hoon KIM | 2017 | Frontiers of Computer Science2017，11，4： | 2 |
| 15 | 简易转速测量系统设计显示文摘介绍了一种基于定时器的转速测量系统的设计与开发。使用直流电动机的转轴来测量其转速,定时器IC 555用于不稳定模式。使用数字存储示波器(DSO)测量的定时器输出波形的频率几乎与转轴的转速成线性比例,而这个转速又与外部输入电压水平的变化成线性关系,由此得到了定时器输出波形频率与转速之间的线性关系。该系统的主要优点是线性输入-输出,体积小,便于携带且成本低。 | Akash Kumar Anindya Debnath Antar Banik Kabirul Islam Mondal Partha Pratim Biswas Rik Bhattacharyya T K Maiti | 2020 | Journal of Measurement Science and Instrumentation2020，11，2： | 2 |
| 16 | Influence of peach(Prunus persica Batsch)phenological stage on the short-term changes in oxidizable and labile pools of soil organic carbon and activities of carbon-cycle enzymes in the North-Western Himalayas显示文摘The labile organic carbon(C)and C-related enzymes are sensitive indicators capturing alterations of soil organic matter(SOM),even in a short-time scale.Although the effects of crop husbandry and land use change on these attributes have been well studied,there is no consensus about how plant phenology may impact them.This study aimed to determine the short-term effect o f six distinct phenological stages(PS-1:full bloom;PS-2:fruit set;PS-3:pit hardening;PS-4:physiological maturity;PS-5:60 d after physiological maturity;and PS-6:fall)o f peach on the changes in soil organic carbon(SOC)fractions of different oxidizability,labile C pools,and C-cycle enzyme activities in soils,for two consecutive years(2015 and 2016)in the North-Western Himalayas(NWH).Peach rhizosphere soils were sampled at the topsoil(0-15 cm)and subsoil(16-30 cm)layers,along with rhizosphere soils from adjacent perennial grasses,which served as a control.Values for most of the assessed parameters,including very labile C,labile C,microbial biomass C,permanganate oxidizable C,dissolved organic C,mineralizable C,amylase activity,and carboxymethyl-cellulase activity,were significantly(P<0.05)higher at PS-3 than at other phenological stages of peach.Conversely,a sudden decline in these soil variables was recorded at PS-5,followed by a slight buildup at PS-6,particularly in the topsoil of the peach orchard.Short-term changes in organic C fractions of different oxidizability,influenced by peach phenological stage,significantly(P<0.05)affected C management index,C pool index,and lability index.Both the C management index and lability index showed their highest values at PS-3 and their lowest values at PS-5,clearly indicating short-term accretion and depletion of SOC,in tandem with the peach phenological events.Principal component analysis suggested that a composite of soil indicators,including microbial biomass C,dissolved organic C,amylase,and invertase,could help detect short-term changes in SOC content.It is concluded that peach phenological events had a major impact on the short-term variations of the studied soil variables,which could be attributed to changes in the above-and belowground plant residues,as well as the extent of nutrients and water acquisition. | Sovan DEBNATH Brij Lai ATTRI Anil KUMAR Arun KISHOR Raj NARAYAN Kanchan SINHA Arpan BHOWMIK Anil SHARMA Desh Beer SINGH | 2020 | Pedosphere2020，30，5： | 2 |
| 17 | Circulatory and hepatic failure at admission predicts mortality of severe scrub typhus patients: A prospective cohort study显示文摘Objective:To study the spectrum and outcome of severe scrub typhus in adult patients and to predict the hospital mortality by organ failure on admission.Methods:This was a prospective observational cohort study conducted between July 2017 and October 2020 at the medical emergency centre of PGIMER,Chandigarh,India.One hundred and twenty-six patients aged≥13 years were diagnosed with scrub typhus.Severe disease was defined as the presence of organ failure based on the Sequential Organ Failure Assessment(SOFA)score on admission.Results:About two-thirds of the patients were from geographic regions outside the endemic sub-Himalayan belt.Fever(99.21%)and dyspnea(79.36%)were the most frequent complaints.Respiratory failure(81.75%)was the most common organ failure,followed by hepatic(52.38%),coagulative(47.62%),circulatory(33.33%),renal(21.43%),and cerebral dysfunction(13.49%).The median(Q1,Q3)SOFA score was 8(6,9),and 48.41%of the patients had a quick-SOFA score≥2.Organ supports with invasive ventilation(40.48%),vasopressors(36.51%),and renal replacement therapy(7.14%)were frequently required.The in-hospital mortality was 11.90% and was independently predicted by circulatory and hepatic failures on multivariate logistic regression(OR 11.12,95%CI 1.73-71.31 and OR 8.49,95%CI 1.18-61.41,respectively).Conclusions:Most patients had pulmonary dysfunction;circulatory or hepatic failure on admission strongly predicts death. | Ashok Kumar Pannu Atul Saroch Saurabh Chandrabhan Sharda Manoj Kumar Debnath Manisha Biswal Navneet Sharma | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，5： | 2 |
| 18 | Study of a static cruciform crack problem in an orthotropic elastic plane显示文摘 | Das S Debnath L | 2000 | Comp Math Applic2000，40，： | 1 |
| 19 | A new type of charge compensating mechanism in Ca5 (PO4)3F: Eu^3+ phosphor 显示文摘 | R Sahoo S K Bhattacharya R Debnath | 2003 | J Solid State Chemistry2003，175，2： | 1 |
| 20 | Regulation of tumor cell dor- mancy by tissue microenvironments and autophagy显示文摘 | Sosa MS Bragado P Debnath J | 2013 | Adv Exp Med Biol2013，734，： | 1 |
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