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11篇 您的检索式:作者名="Anoop Gupta"
    题名 作者 年代 出处 被引量
1Plasma cathepsin L:A prognostic marker for pancreatic cancer显示文摘AIM:To assess the prognostic significance of cathepsin L,a cysteine protease that degrades the peri-tumoral tissue,in patients with pancreatic cancer.METHODS:Plasma samples from 127 pancreatic cancer patients were analyzed for cathepsin L levels by ELISA.Out of these patients,25 underwent surgeryand their paraffin-embedded tissue was analyzed for cathepsin L expression by immunohistochemistry.Survival of patients and clinicopathological parameters was correlated with cathepsin L expression in plasma and tissue using appropriate statistical analysis.RESULTS:The mean(±SD)cathepsin L in plasma samples of pancreatic cancer patients was 5.98±2.5ng/m L that was significantly higher compared to the levels in healthy controls(3.83±0.45)or chronic pancreatitis patients(3.97±1.06).Using ROC curve,a cut-off level of 5.0 ng/m L was decided for survival analysis.Elevated plasma levels of cathepsin L were found to be associated with poor prognosis(P=0.01)in multivariate analysis.The plasma levels of the protease decreased after surgery.Though no significant correlation was seen between plasma and tissue expression of this protease,a trend did emerge that high cathepsin L expression in tissue correlated with its high levels in plasma.CONCLUSION:Cathepsin L levels in plasma of pancreatic cancer patients may be used as a potential prognostic marker for the disease.Nidhi Singh Prasenjit Das Surabhi Gupta Vikas Sachdev Siddhartha Srivasatava Siddhartha Datta Gupta Ravindra Mohan Pandey Peush Sahni Shyam S Chauhan Anoop Saraya 2014World Journal of Gastroenterology2014,20,46:2
2Prognostic Significance of Extracellular Matrix Degrading Enzymes—Cathepsin L and Matrix Metalloproteases-2 [MMP-2] in Human Pancreatic Cancer显示文摘Nidhi Singh Prasenjit Das Siddhartha Datta Gupta Peush Sahni R. M. Pandey Surabhi Gupta Shyam S. Chauhan Anoop Saraya 2013Cancer Investigation2013,,7:2
3Cache-Coherent Distributed Shared Memory: Perspectives on Its Development and Future Challenges显示文摘John Hennessy Mark Heinrich Anoop Gupta 1999Proceedings of the IEEE1999,87,3:1
4Transgenic indica rice cv IR 50 overex pressing Vigna aconitifolia Δ (1) pyrroline -5 carboxylate synthetase cDNA shows tolerance to high salt显示文摘Anoop N Gupta A K 2003Journal of Plant Biochemistry and Biotechnology2003,12,:1
5Transgenic indica rice cv IR 50 over-expressiong Vigna aconitifolia Delta(1)-pyrroline 5 carboxylate synthetase eDNA shows tolerance to high salt显示文摘Anoop N Gupta A K 2003Journal of Plant Biochemistry and Biotechnology2003,12,2:1
6Correlation of regional cardiovascular disease mortality in India with lifestyle and nutritional factors显示文摘Rajeev Gupta Anoop Misra Prem Pais Priyanka Rastogi V.P. Gupta 2005International Journal of Cardiology2005,,3:1
7High Levels of Cell-Free Circulating Nucleic Acids in Pancreatic Cancer are Associated With Vascular Encasement, Metastasis and Poor Survival显示文摘Nidhi Singh Surabhi Gupta R. M. Pandey Shyam S. Chauhan Anoop Saraya 2015Cancer Investigation2015,,3:1
8Consensus statement on management of dyslipidemia in Indian subjects显示文摘K. Sarat Chandra Manish Bansal Tiny Nair S.S. Iyengar Rajeev Gupta Subhash C. Manchanda P.P. Mohanan V. Dayasagar Rao C.N. Manjunath J.P.S. Sawhney Nakul Sinha A.K. Pancholia Sundeep Mishra Ravi R. Kasliwal Saumitra Kumar Unni Krishnan Sanjay Kalra Anoop 2014Indian Heart Journal2014,,:1
9Maternal Mortality Ratio and predicators of maternal deaths in select desert districts in Rajasthan-a community-based survey and case-control study显示文摘Shiv D Gupta Anoop Khanna 0,,:1
10SPLASH:stanford parallel applications for shared memory显示文摘Pal Singh J Wolf-Dietrich Weber Anoop Gupta 1992Computer Architecture News1992,20,1:1
11Transgenic indica rice CV IR-50 over expressing vigna aconitifolia-pyrroline-5-carboxylatelate synthetase cDNA shows tolerance to high salt显示文摘Anoop N Gupta AK 2003J plant Biochem and Biotech2003,12,2:1
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