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| 1 | Transjugular intrahepatic portosystemic shunt in cirrhosis: An exhaustive critical update显示文摘More than five decades after it was originally conceptualized as rescue therapy for patients with intractable variceal bleeding,the transjugular intrahepatic portosystemic shunt(TIPS)procedure continues to remain a focus of intense clinical and biomedical research.By the impressive reduction in portal pressure achieved by this intervention,coupled with its minimally invasive nature,TIPS has gained increasing acceptance in the treatment of complications of portal hypertension.The early years of TIPS were plagued by poor long-term patency of the stents and increased incidence of hepatic encephalopathy.Moreover,the diversion of portal flow after placement of TIPS often resulted in derangement of hepatic functions,which was occasionally severe.While the incidence of shunt dysfunction has markedly reduced with the advent of covered stents,hepatic encephalopathy and instances of early liver failure continue to remain a significant issue after TIPS.It has emerged over the years that careful selection of patients and diligent post-procedural care is of paramount importance to optimize the outcome after TIPS.The past twenty years have seen multiple studies redefining the role of TIPS in the management of variceal bleeding and refractory ascites while exploring its application in other complications of cirrhosis like hepatic hydrothorax,portal hypertensive gastropathy,ectopic varices,hepatorenal and hepatopulmonary syndromes,non-tumoral portal vein thrombosis and chylous ascites.It has also been utilized to good effect before extrahepatic abdominal surgery to reduce perioperative morbidity and mortality.The current article aims to review the updated literature on the status of TIPS in the management of patients with liver cirrhosis. | Sasidharan Rajesh Tom George Cyriac Abby Philips Rizwan Ahamed Sandeep Kumbar Narain Mohan Meera Mohanan Philip Augustine | 2020 | World Journal of Gastroenterology2020，26，37： | 26 |
| 2 | Update on diagnosis and management of sepsis in cirrhosis: Current advances显示文摘Sepsis and septic shock are catastrophic disease entities that portend high mortality in patients with cirrhosis.In cirrhosis,hemodynamic perturbations,immune dysregulation,and persistent systemic inflammation with altered gut microbiota in the background of portal hypertension enhance the risk of infections and resistance to antimicrobials.Patients with cirrhosis develop recurrent lifethreatening infections that progress to multiple organ failure.The definition,pathophysiology,and treatment options for sepsis have been ever evolving.In this exhaustive review,we discuss novel advances in the understanding of sepsis,describe current and future biomarkers and scoring systems for sepsis,and delineate newer modalities and adjuvant therapies for the treatment of sepsis from existing literature to extrapolate the same concerning the management of sepsis in cirrhosis.We also provide insights into the role of gut microbiota in initiation and progression of sepsis and finally,propose a treatment algorithm for management of sepsis in patients with cirrhosis. | Cyriac Abby Philips Rizwan Ahamed Sasidharan Rajesh Tom George Meera Mohanan Philip Augustine | 2020 | World Journal of Hepatology2020，12，8： | 2 |
| 3 | Synthesis, spectroscopic characterization, and thermal decomposition kinetics of some lanthanide(III) nitrate complexes of 2-(N-o-hydroxyacetophenone) amino-3-carboxyethyl-4,5,6,7-tetrahydrobenzo[b]thiophene显示文摘Complexes of La(III), Ce(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Dy(III), Yb(III), and Lu(III) with 2-(N-o-hydroxyacetophenone)amino-3-carboxyethyl-4,5,6,7-tetrahydrobenzo[b]thiophene (HAAT) formed by the condensation of o-hydroxyacetophenone and 2-amino-3-carboxyethyl-4,5,6,7-tetrahydrobenzo[b]thiophene were synthesized and characterized on the basis of elemental analyses, molar conductance measurements, magnetic susceptibility data, UV-Visible, IR, and NMR spectral studies. The spectral data revealed that the ligand acted as a neutral tridentate coordinating to the metal ion through ONO donor sequence. A coordination number nine was proposed for the complexes. Thermal decomposition studies of the ligand and lanthanum(III) complex were carried out and kinetic parameters were calculated using Coats-Redfern equation. The decomposition reactions followed random nucleation mechanism with one nucleus on each particle. | K. Mohanan M. Thankamony B. Sindhu Kumari | 2008 | Journal of Rare Earths2008，26，4： | 2 |
| 4 | Vibration of thin rings of rectangular cross-section 显示文摘 | Charnley T Perrin R Mohanan V | 1989 | Sounds and Vibration1989，134，： | 1 |
| 5 | Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice显示文摘 | Yamamoto HA Mohanan PV | 2003 | Brain Res2003，964，1： | 1 |
| 6 | Hydrometallurgical processing of lead-bearing materials for the recovery of lead and silver as lead concentrate and lead metal显示文摘 | R Raghavan P.K Mohanan S.R Swarnkar | 2000 | Hydrometallurgy2000，，2： | 1 |
| 7 | Hydrometallurgical Processing of Lead-bearing Materials for the Recovery of Lead and Silver as Lead Concentrate and Lead Metal显示文摘 | Raghavan R Mohanan P K Swarnkar S R | 2000 | Hydrometallurgy2000，58，36： | 1 |
| 8 | Diseases of Casuarina equisetifolia in India显示文摘 | Mohanan C Sharma JK | 1993 | Commonw For Rev1993，72，： | 1 |
| 9 | Melatonin attenuates brain mitochondria DNA damage induced by potassium cyanide in vivo and in vitro显示文摘 | Yamamoto HA Mohanan PV | 2002 | Toxicology2002，179，： | 1 |
| 10 | Prevalence of duplex collecting systems in familial vesicoureteral reflux 显示文摘 | Hunziker M Mohanan N Menezes M | 2010 | Pediatr Surg lnt2010，26，1： | 1 |
| 11 | Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the urinary bladder 显示文摘 | CHANG s HYPOLITE JA MOHANAN S | 2009 | Lab Invest2009，89，7： | 1 |
| 12 | Ganglioside GT1B and melatonin in-hibit brain mitochondrial DNA damage and seizures induced bykainic acid in mice显示文摘 | Yamamoto HA Mohanan PV | 2003 | Brain research2003，964，1： | 1 |
| 13 | Ganglioside GTIB and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice显示文摘 | Yamamoto HA Mohanan PV | 2003 | Brain Res2003，964，1： | 1 |
| 14 | Spermatotoxicity of a protein isolated from the root of Achyranthes aspera : a comparative study with gossypol显示文摘 | Mohanan Nair Mohana Kumari Anuja Ramachandran Nair Saraswathy Amma Nithya Chellam Rajamanickam Indira Madambath | 2010 | Contraception2010，，4： | 1 |
| 15 | Constitutive Interferon-Inducible Protein 16-Inflammasome Activation during Epstein-Barr Virus Latency I, II, and III in B and Epithelial Cells显示文摘 | Mairaj Ahmed Ansari Vivek Vikram Singh Sujoy Dutta Mohanan Valiya Veettil Dipanjan Dutta Leela Chikoti Jie Lu David Everly Bala Chandran | 2013 | Journal of Virology2013，，15： | 1 |
| 16 | Hydrometallurgical processing of lead-bearing materials for the recovery of lead and silver as lead concentrate and lead metal显示文摘 | R Raghavan P.K Mohanan S.R Swarnkar | 2000 | Hydrometallurgy2000，，2： | 1 |
| 17 | Microwave characterization of BaCe2Ti5 O15 and Ba5Nb4O15 ceramic dielectric resonators using whispering gallery mode methord 显示文摘 | Ratheesh R Sebastian M T Mohanan P | 2000 | Materials Letters2000，45，： | 1 |
| 18 | 显示文摘 | Mohanan S Grob A Herr U | 2006 | J Appl Phys2006，99，08： | 1 |
| 19 | Melatonin attenuates brain mitoch- -ondria DNA damage induced by potassium cyanide in vivo and in vitro显示文摘 | Yamamoto HA Mohanan PV | 2002 | Toxicology2002，179，12： | 1 |
| 20 | IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection显示文摘 | Nagaraj Kerur Mohanan Valiya Veettil Neelam Sharma-Walia Virginie Bottero Sathish Sadagopan Pushpalatha Otageri Bala Chandran | 2011 | Cell Host & Microbe2011，，5： | 1 |
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