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| 1 | Elevated blood pressure: Our family's fault?The genetics of essential hypertension显示文摘AIM: To provide an updated review on current genetic aspects possibly affecting essential hypertension(EH), and to further elucidate their role in EH. METHODS: We searched for genetic and epigenetic factors in major studies associated with EH between Jan 2008-Oct 2013 using PubMed. We limited our search to reviews that discussed mostly human studies, and were accessible through the university online re-source. We found 11 genome wide association studies(GWAS), as well as five methylation and three miRNA studies that fit our search criteria. A distinction was not made between genes with protective effects or nega-tive effects, as this article is only meant to be a sum-mary of genes associated with any aspect of EH.RESULTS: We found 130 genes from the studies that met our inclusion/exclusion criteria. Of note, genes withmultiple study references include: STK39, CYP17A1, MTHFR-NPPA, MTHFR-NPPB, ATP2B1, CSK, ZNF652, UMOD, CACNB2, PLEKHA7, SH2B3, TBX3-TBX5, ULK4, CSK-ULK3, CYP1A2, NT5C2, CYP171A, PLCD3, SH2B3, ATXN2, CACNB2, PLEKHA7, SH2B3, TBX3-TBX5, ULK4, and HFE. The following genes overlapped between the genetic studies and epigenetic studies: WNK4 and BDKRB2. Several of the identified genes were found to have functions associated with EH. Many epigenetic factors were also correlated with EH. Of the epigenetic factors, there were no articles discussing siRNA and its effects on EH that met the search criteria, thus the topic was not included in this review. Among the miRNA tar-gets found to be associated with EH, many of the genes involved were also identified in the GWAS studies.CONCLUSION: Genetic hypertension risk algorithms could be developed in the future but may be of limited benefit due to the multi-factorial nature of EH. With emerging technologies, like next-generation sequenc-ing, more direct causal relationships between genetic and epigenetic factors affecting EH will likely be discov-ered creating a tremendous potential for personalized medicine using pharmacogenomics. | Aniket Natekar Randi L Olds Meghann W Lau Kathleen Min Karra Imoto Thomas P Slavin | 2014 | World Journal of Cardiology2014，6，5： | 7 |
| 2 | Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB-231 to revert the TGF-β-induced epithelial–mesenchymal transition显示文摘Objective:Triple-negative breast cancer(TNBC)is highly metastatic,and there is an urgent unmet need to develop novel therapeutic strategies leading to the new drug discoveries against metastasis.The transforming growth factor-β(TGF-β)is known to promote the invasive and migratory potential of breast cancer cells through induction of epithelial–mesenchymal transition(EMT)via the ERK/NF-κB/Snail signaling pathway,leading to breast cancer metastasis.Targeting this pathway to revert the EMT would be an attractive,novel therapeutic strategy to halt breast cancer metastasis.Methods:Effects of enterolactone(EL)on the cell cycle and apoptosis were investigated using flow cytometry and a cleaved caspase-3 enzyme-linked immunosorbent assay(ELISA),respectively.Effects of TGF-βinduction and EL treatment on the functional malignancy of MDA-MB-231 breast cancer cells were investigated using migration and chemo-invasion assays.The effects of EL on EMT markers and the ERK/NF-κB/Snail signaling pathway after TGF-βinduction were studied using confocal microscopy,quantitative reverse transcription polymerase chain reaction(q RT-PCR),Western blot,and flow cytometry.Results:Herein,we report that EL exhibits a significant antimetastatic effect on MDA-MB-231 cells by almost reverting the TGF-β-induced EMT in vitro.EL downregulates the mesenchymal markers N-cadherin and vimentin,and upregulates the epithelial markers E-cadherin and occludin.It represses actin stress fiber formation via inhibition of mitogen-activated protein kinase p-38(MAPK-p38)and cluster of differentiation 44(CD44).EL also suppresses ERK-1/2,NF-κB,and Snail at the m RNA and protein levels.Conclusions:Briefly,EL was found to inhibit TGF-β-induced EMT by blocking the ERK/NF-κB/Snail signaling pathway,which is a promising target for breast cancer metastasis therapy. | Aniket V.Mali Asavari A.Joshi Mahabaleshwar V.Hegde Shivajirao S.Kadam | 2018 | Cancer Biology & Medicine2018，15，2： | 6 |
| 3 | Combustion performance studies of aluminum and boron based composite solid propellants in sub-atmospheric pressure regimes显示文摘The aim of present study is to investigate the burning rate,ignition delay,and flame characteristics of ammonium perchlorate(AP)-hydroxyl terminated poly-butadiene(HTPB)[AP/HTPB]based composite propellants(CSP's)in sub-atmospheric pressure regimes(13 kPae100 kPa).Several fuels and catalyzed were used to evaluate their effects on the combustion characteristics of AP based propellants in sub-atmospheric pressure regimes.In fuels,aluminum(Al)and boron(B)were selected as metallic and non-metallic fuel respectively.While in catalyst,butyl ferrocene(B.F.)and ferric oxide(F.O.)were selected as liquid and solid catalyst respectively.Apart from these,other ingredients that were used are di-octyl adipate(DOA),toluene di-isocyanate(TDI),and glycerol.The article throws some light on the burning rate and ignition delay properties for these new classes of prepared propellant samples.At subatmospheric pressures,all propellants are susceptible to irregular burning with the ejection of soot's,fumes,and unburned particles.F.O.based catalyzed propellants can sustain its combustion up to the lowest pressure. | Pratim Kumar Mayank Varshney Aniket Manash | 2019 | Propulsion and Power Research2019，8，4： | 3 |
| 4 | Fungal diversity notes 367-490:taxonomic and phylogenetic contributions to fungal taxa显示文摘This is a continuity of a series of taxonomic papers where materials are examined,described and novel combinations are proposed where necessary to improve our traditional species concepts and provide updates on their classification.In addition to extensive morphological descriptions and appropriate asexual and sexual connections,DNA sequence data are also analysed from concatenated datasets(rDNA,TEF-a,RBP2 and b-Tubulin)to infer phylogenetic relationships and substantiate systematic position of taxa within appropriate ranks.Wherever new species or combinations are being proposed,we apply an integrative approach(morphological and molecular data as well as ecological features wherever applicable).Notes on 125 fungal taxa are compiled in this paper,including eight new genera,101 new species,two new combinations,one neotype,four reference specimens,new host or distribution records for eight species and one alternative morphs.The new genera introduced in this paper are Alloarthopyrenia,Arundellina,Camarosporioides,Neomassaria,Neomassarina,Neotruncatella,Paracapsulospora and Pseudophaeosphaeria.The new species are Alfaria spartii,Alloarthopyrenia italica,Anthostomella ravenna,An.thailandica,Arthrinium paraphaeospermum,Arundellina typhae,Aspergillus koreanus,Asterina cynometrae,Bertiella ellipsoidea,Blastophorum aquaticum,Cainia globosa,Camarosporioides phragmitis,Ceramothyrium menglunense,Chaetosphaeronema achilleae,Chlamydotubeufia helicospora,Ciliochorella phanericola,Clavulinopsis aurantiaca,Colletotrichum insertae,Comoclathris italica,Coronophora myricoides,Cortinarius fulvescentoideus,Co.nymphatus,Co.pseudobulliardioides,Co.tenuifulvescens,Cunninghamella gigacellularis,Cyathus pyristriatus,Cytospora cotini,Dematiopleospora alliariae,De.cirsii,Diaporthe aseana,Di.garethjonesii,Distoseptispora multiseptata,Dis.tectonae,Dis.tectonigena,Dothiora buxi,Emericellopsis persica,Gloniopsis calami,Helicoma guttulatum,Helvella floriforma,H.oblongispora,Hermatomyces subiculosa,Juncaceicola italica,Lactarius dirkii,Lentithecium unicellulare,Le.voraginesporum,Leptosphaeria cirsii,Leptosphaeria irregularis,Leptospora galii,Le.thailandica,Lindgomyces pseudomadisonensis,Lophiotrema bambusae,Lo.fallopiae,Meliola citri-maximae,Minimelanolocus submersus,Montagnula cirsii,Mortierella fluviae,Muriphaeosphaeria ambrosiae,Neodidymelliopsis ranunculi,Neomassaria fabacearum,Neomassarina thailandica,Neomicrosphaeropsis cytisi,Neo.cytisinus,Neo.minima,Neopestalotiopsis cocoe¨s,Neopestalotiopsis musae,Neoroussoella lenispora,Neotorula submersa,Neotruncatella endophytica,Nodulosphaeria italica,Occultibambusa aquatica,Oc.chiangraiensis,Ophiocordyceps hemisphaerica,Op.lacrimoidis,Paracapsulospora metroxyli,Pestalotiopsis sequoiae,Peziza fruticosa,Pleurotrema thailandica,Poaceicola arundinis,Polyporus mangshanensis,Pseudocoleophoma typhicola,Pseudodictyosporium thailandica,Pseudophaeosphaeria rubi,Purpureocillium sodanum,Ramariopsis atlantica,Rhodocybe griseoaurantia,Rh.indica,Rh.luteobrunnea,Russula indoalba,Ru.pseudoamoenicolor,Sporidesmium aquaticivaginatum,Sp.olivaceoconidium,Sp.pyriformatum,Stagonospora forlicesenensis,Stagonosporopsis centaureae,Terriera thailandica,Tremateia arundicola,Tr.guiyangensis,Trichomerium bambusae,Tubeufia hyalospora,Tu.roseohelicospora and Wojnowicia italica.New combinations are given for Hermatomyces mirum and Pallidocercospora thailandica.A neotype is proposed for Cortinarius fulvescens.Reference specimens are given for Aquaphila albicans,Leptospora rubella,Platychora ulmi and Meliola pseudosasae,while new host or distribution records are provided for Diaporthe eres,Di.siamensis,Di.foeniculina,Dothiorella iranica,Do.sarmentorum,Do.vidmadera,Helvella tinta and Vaginatispora fuckelii,with full taxonomic details.An asexual state is also reported for the first time in Neoacanthostigma septoconstrictum.This paper contributes to a more comprehensive update and improved identification of many ascomycetes and basiodiomycetes. | Kevin D.Hyde Sinang Hongsanan Rajesh Jeewon D.Jayarama Bhat Eric H.C.McKenzie E.B.Gareth Jones Rungtiwa Phookamsak Hiran A.Ariyawansa Saranyaphat Boonmee Qi Zhao Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Supharat Banmai Putarak Chomnunti Bao-Kai Cui Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Nimali Ide Silva Asha J.Dissanayake Mingkwan Doilom Anusha H.Ekanayaka Tatiana Baptista Gibertoni Aristóteles Góes-Neto Shi-Ke Huang Subashini C.Jayasiri Ruvishika S.Jayawardena Sirinapa Konta Hyang Burm Lee Wen-Jing Li Chuan-Gen Lin Jian-Kui Liu Yong-Zhong Lu Zong-Long Luo Ishara S.Manawasinghe Patinjareveettil Manimohan Ausana Mapook Tuula Niskanen Chada Norphanphoun Moslem Papizadeh Rekhani H.Perera Chayanard Phukhamsakda Christian Richter AndréL.C.Mde A.Santiago E.Ricardo Drechsler-Santos Indunil C.Senanayake Kazuaki Tanaka T.M.D.S.Tennakoon Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Benjarong Thongbai Alfredo Vizzini Dhanushka N.Wanasinghe Nalin N.Wijayawardene Hai-Xia Wu Jing Yang Xiang-Yu Zeng Huang Zhang Jin-Feng Zhang Timur S.Bulgakov Erio Camporesi Ali H.Bahkali Mohammad A.Amoozegar Lidia Silva Araujo-Neta Joseph F.Ammirati Abhishek Baghela R.P.Bhatt Dimitar Bojantchev Bart Buyck Gladstone Alves da Silva Catarina Letícia Ferreira de Lima Rafael JoséVilela de Oliveira Carlos Alberto Fragoso de Souza Yu-Cheng Dai Bálint Dima Tham Thi Duong Enrico Ercole Fernando Mafalda-Freire Aniket Ghosh Akira Hashimoto Sutakorn Kamolhan Ji-Chuan Kang Samantha C.Karunarathna Paul M.Kirk Ilkka Kytovuori Angela Lantieri Kare Liimatainen Zuo-Yi Liu Xing-Zhong Liu Robert Lücking Gianfranco Medardi Peter E.Mortimer Thi Thuong Thuong Nguyen Itthayakorn Promputtha K.N.Anil Raj Mateus A.Reck Saisamorn Lumyong Seyed Abolhassan Shahzadeh-Fazeli Marc Stadler Mohammad Reza Soudi Hong-Yan Su Takumasa Takahashi Narumon Tangthirasunun Priyanka Uniyal Yong Wang Ting-Chi Wen Jian-Chu Xu Zhong-Kai Zhang Yong-Chang Zhao Jun-Liang Zhou Lin Zhu | 2016 | Fungal Diversity2016，，5： | 2 |
| 5 | Primary and secondary carbonaceous species in the atmosphere of Western Riverside County, California显示文摘 | Kwangsam Na Aniket A. Sawant Chen Song David R. Cocker | 2003 | Atmospheric Environment2003，，9： | 2 |
| 6 | Diagnostic assays developed for the control of foot-andmouth disease in India显示文摘Foot-and-mouth disease(FMD) is a highly contagious and economically devastating disease of livestock, primarily affecting cattle, buffalo and pigs. FMD virus serotypes O, A and Asia1 are prevalent in India and systematic efforts are on to control and eventually eradicate the disease from the country. FMD epidemiology is complex due to factors like co-circulation, extinction, emergence and re-emergence of genotypes/lineages within the three serotypes, animal movement, diverse farm practices and large number of susceptible livestock in the country. Systematic vaccination, prompt diagnosis, strict biosecurity measures, and regular monitoring of vaccinal immunity and surveillance of virus circulation are indispensible features for the effective implementation of the control measures. Availability of suitable companion diagnostic tests is very important in this endeavour. In this review, the diagnostic assays developed and validated in India and their contribution in FMD control programme is presented. | Gaurav Kumar Sharma Sonalika Mahajan Rakesh Matura Saravanan Subramaniam Rajeev Ranjan Jitendra Biswal Manoranjan Rout Jajati Keshari Mohapatra Bana Bihari Dash Aniket Sanyal Bramhadev Pattnaik | 2015 | World Journal of Virology2015，4，3： | 2 |
| 7 | Reconstruction of post-traumatic upper extremity soft tissue defects with pedicled flaps: An algorithmic approach to clinical decision making显示文摘Purpose:Pedicled flaps are still the workhorse flaps for reconstruction of upper limb soft tissue defects in many centers across the world. They are lifeboat options for coverage in vessel deplete wounds. In spite of their popularity existing algorithms are limited to a particular region of upper limb;a general algorithm involving entire upper limb which helps in clinical decision making is lacking. We attempt to propose one for the day to day clinical practice.Methods:A retrospective analysis of patients who underwent pedicled flaps for coverage of post-traumatic upper extremity (arm, elbow, forearm, wrist & hand) soft tissue defects within the period of January 2016 to October 2017 was performed. Patients were divided into groups according to the anatomical location of the defects. The flaps performed for different anatomical regions were enlisted. Demographic data and complications were recorded. An algorithm was proposed based on our experience, with a particular emphasis made to approach to clinical decision making.Results:Two hundred and twelve patients were included in the study. Mean age was 27.3 years (range: 1-80 years), 180 were male, and 32 were female. Overall flap success rate was 98%, the following complications were noted marginal flap necrosis requiring no additional procedure other than local wound care in 32 patients (15%), partial flap necrosis requiring flap advancement or extra flap in 15 patients (7%), surgical site infection in 11 patients (5%), flap dehiscence requiring re-suturing in 5 patients (2.4%), total flap necrosis 4 patients (2%).Conclusion:The proposed algorithm allows a reliable and consistent method for addressing diverse soft tissue defects in the upper limb with high success rate. | Ravikiran Naalla Shashank Chauhan Aniket Dave Maneesh Singhal | 2018 | Chinese Journal of Traumatology2018，21，6： | 2 |
| 8 | Primary and secondary carbonaceous species in the atmosphere of Western Riverside County, California显示文摘 | Kwangsam Na Aniket A. Sawant Chen Song David R. Cocker | 2003 | Atmospheric Environment2003，，9： | 2 |
| 9 | A context-aware scheme for privacy-preserving location-based services显示文摘 | Aniket Pingley Wei Yu Nan Zhang Xinwen Fu Wei Zhao | 2012 | Computer Networks2012，，11： | 1 |
| 10 | Emergence of a New Strain of Type O Foot-and-Mouth Disease Virus: Its Phylogenetic and Evolutionary Relationship with the PanAsia Pandemic Strain显示文摘 | Divakar Hemadri Chakradhar Tosh Aniket Sanyal Ramamurthy Venkataramanan | 2002 | Virus Genes Aug 2002 252002，，： | 1 |
| 11 | A link a- vailability-based QoS-aware routing protocol for mobile ad hoc sensor networks 显示文摘 | Ming Yu Aniket Malvankar Wei Su | 2007 | Computer Communica- tions2007，30，18： | 1 |
| 12 | A link a-vailability-based QoS-aware routing protocol for mobilead hoc sensor networks 显示文摘 | Ming Yu Aniket Malvankar Wei Su | 2007 | Computer communica-tions2007，30，18： | 1 |
| 13 | A Dynamic Clustering and Energy Efficient Routing Technique for Sensor Networks显示文摘 | Yu Ming Kin K Leung Aniket Malvankar | 2007 | IEEE Trans on Wireless Communications2007，6，8： | 1 |
| 14 | The quest for a globally comprehensible Russula language显示文摘Since 2007,the quality of Russula descriptions has improved and the use of molecular support for species delimitation and the number of published new species has increased.However,the description style is not consistent and has regional or author-specific patterns.Most recent publications still favour descriptions of spores compared to hymenium and pileipellis elements,and usually only the spore size is provided with statistical support.This study proposes standards for descriptions of the microscopic structure of Russula species(Russulaceae,Agaricomycetes).We present the description template,the template measurements table,the specific terminology and the essential chemical reagents.The proposed standards were tested by mycologists from 11 countries who met at the Russula Microscopy Workshop in Slovakia.Descriptions of 26 species from 9 countries and four continents were prepared,among them R.amarissima,R.castanopsidis,R.seperina and R.subtilis are re-described and 15 species are introduced as new:R.abietiphila,R.amerorecondita,R.aurantioflava,R.echidna,R.flavobrunnescens,R.fluvialis,R.fortunae,R.garyensis,R.gemmata,R.laevis,R.madrensis,R.olivaceohimalayensis,R.purpureogracilis,R.sancti-pauli and R.wielangtae.Seven descriptions for candidate new species are provided without a formal name assignment.Pairwise comparison of species described in this study with available similar descriptions of related species suggests that microscopic characters from all parts of the basidiomata can be equally important for species recognition and they deserve the same treatment including number of measurements and statistics.The majority of recent studies does not recognise differences between the pileus margin and centre,but more than one-third of the species described in this study show distinct differences between the pileus areas,emphasizing the importance to specify the origin of pileipellis observations.This study proved that there is frequently insufficient difference in the ITS barcode between closely related species and that it is necessary to use more genetic markers combined with ecological and geographical data. | Slavomır Adamcik Brian Looney Miroslav Cabon Sona Jancovicova Katarina Adamcikova Peter G.Avis Magdalena Barajas Rajendra P.Bhatt Adriana Corrales Kanad Das Felix Hampe Aniket Ghosh Genevieve Gates Ville Kalviainen Abdul Nasir Khalid Munazza Kiran Ruben De Lange Hyun Lee Young Woon Lim Alejandro Kong Cathrin Manz Clark Ovrebo Malka Saba Tero Taipale Annemieke Verbeken Komsit Wisitrassameewong Bart Buyck | 2019 | Fungal Diversity2019，，6： | 1 |
| 15 | 人工耳蜗植入中的耳蜗电图:发展、应用和未来方向显示文摘目的本研究的目的是全面概述耳蜗电图的电生理及其历史,讨论其在人工耳蜗植入中新近的应用,并探讨在这个不断深入领域中所开展的研究。耳蜗电图是一种记录内耳不同组分和外周蜗神经对声刺激反应产生电位的电生理技术。耳蜗电图可解析为:①耳蜗微音电位,②听神经音电位,③总和电位,④听神经复合动作电位。数十年来,随着技术上的不断改进,对记录电位的理解也在不断更新。耳蜗电图历来主要应用于梅尼埃病的诊断评估。然而,近十年来耳蜗电图的应用聚焦到人工耳蜗植入上。具有残余听力的患者在人工耳蜗植入后,联合电声刺激可以改善听力和言语。尽管术者在电极插入过程中尽量减轻组织损伤,但患者术后听力保存率各异。在植入耳蜗期间,当术者插入电极阵列时,实时耳蜗电图可以检测耳蜗局部区域诱发的频率特异性耳蜗微音电位。在耳蜗外记录耳蜗电图,记录电极可以放置于鼓岬、镫骨或鼓膜。耳蜗内耳蜗电图记录可以通过将记录电极插入耳蜗,或者使用人工耳蜗中的1个电极作为记录电极。术中耳蜗电图信号的丧失可能提示电极插入导致的耳蜗损伤,然而两者之间的关系尚存在争议。在人工耳蜗电极植入时监测耳蜗损伤有望改善听力保留结果、改良手术技术以及改进电极设计。 | Jason H.Barnes Linda X.Yin Aniket A.Saoji Matthew L.Carlson 王鹏军(译) 殷善开(审校) | 2021 | 中华耳鼻咽喉头颈外科杂志2021，56，9： | 1 |
| 16 | Silver nanoparticles as a new generation of antimicrobials 显示文摘 | Mahendra R Alka Y Aniket G | 2009 | Biotechnology Advances2009，27，1： | 1 |
| 17 | Design, Synthesis and Pharmacological Screening of Novel Antihypertensive Agents Using Hybrid Approach显示文摘 | Shashikant V. Bhandari Kailash G. Bothara Ajit A. Patil Trupti S. Chitre Aniket P. Sarkate Suraj T. Gore Sudarshan C. Dangre Chetan V. Khachane | 2008 | Bioorganic & Medicinal Chemistry2008，，1： | 1 |
| 18 | Deep vein thrombosis:Current status and nanotechnology advances显示文摘 | WADAJKAR ANIKET S SANTIMANO | 2013 | Biotechnology Advances:An International Review Journal2013，31，5： | 1 |
| 19 | Synthesis, Antifungal Activity, and Docking Study of Some New 1,2, 4-triazole Analogs 显示文摘 | Jaiprakash N S Deepak K L Aniket P S | 2011 | Chern Biol Drug Des2011，78，： | 1 |
| 20 | Dual-responsive polymer-coated iron oxide nanoparticles for drug delivery and imaging applications显示文摘 | Varsha Sundaresan Jyothi U. Menon Maham Rahimi Kytai T. Nguyen Aniket S. Wadajkar | 2014 | International Journal of Pharmaceutics . 2014 (1-2)2014，，1： | 1 |
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