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| 1 | 经腹机器人辅助腹腔镜肾部分切除术治疗T2期肾肿瘤的国际多中心临床研究显示文摘目的通过国际多中心研究探讨临床T2期肾肿瘤行经腹机器人辅助腹腔镜肾部分切除术的安全性及有效性。方法回顾性分析2012年1月至2017年12月国际19家泌尿中心378例临床T2期肾肿瘤行经腹机器人肾部分切除术和经腹机器人根治性肾切除术患者的临床资料。根据手术方式不同,分为部分切除组和根治组。部分切除组159例,男118例,女41例;年龄(59.3±13.2)岁,体重指数(28.7±5.4) kg/m^2,术前GFR (77.3±22.1)ml/min;肿瘤位于左侧72例,右侧87例;肿瘤直径(83±16)mm;R.E.N.A.L.评分(8.6±2.2)分。根治组219例,男156例,女63例;年龄(62.0±12.9)岁,体重指数(28.7±6.1) kg/m^2,术前GFR (71.4±20.3)ml/min;肿瘤位于左侧112例,右侧105例,双侧2例;肿瘤直径(92±25)mm;R.E.N.A.L.评分(9.7±1.5)分。两组患者性别、体重指数、肿瘤位置的差异均无统计学意义(P〉0.05)。部分切除组患者年龄、肿瘤直径、R.E.N.A.L.评分均低于根治组(P〈0.05),术前GFR优于根治组(P=0.012)。比较两组围手术期资料、肿瘤病理类型、随访时间、复发时间及术后GFR等。结果378例手术均顺利完成。部分切除组手术时间中位值150 min(65-353 min),短于根治组[180 min(85-361 min),P〈0.001],术中出血量中位值150 ml(40-3 000 ml),多于根治组[100 ml (10-1 100 ml),P〈0.001]。术中并发症发生率部分切除组为5.7%(9/159),根治组为3.2%(7/219),两组差异无统计学意义(P=0.240)。部分切除组术后并发症发生率高于根治组[19.5%(31/159)与10.5%(23/219),P=0.014],但≥3级并发症发生率的差异无统计学意义[4.4%(7/159)与2.3%(5/219),P=0.246]。部分切除组无复发生存率高于根治组[91.4%(117/128)与81.9%(167/204),P=0.013]。部分切除组术后GFR降低值16.9 ml/min(10.4-84.7 ml/min)明显少于根治组29.0 ml/min(14.0-54.0 ml/min),肾部分切除术更利于术后肾功能的保护(P〈0.001)。结论临床T2期肾肿瘤行机器人肾部分切除术可获得有效的肿瘤控制率,同时可以更好地保护肾功能,可作为临床T2期肾肿瘤有效的手术方式。 | 过菲 张超 王富博 王林辉 杨庆 叶华茂 吕晨 肖成武 汪洋 Giuseppe Simone Ithaar Derweesh Andrea Minervini Daniel Eun Francesco Porpiglia Sisto Perdona James Porter Matteo Ferro Alexandre Mottrie Robert Uzzo Luigi Schips Wesley White Ken Jacobsohn Prokar Dasgupta Riccardo Autorino Clayton Lau Chandru Sundaram Umberto Capitanio 孙颖浩 杨波 | 2018 | 中华泌尿外科杂志2018，39，6： | 8 |
| 2 | VHL and HIF-1α: gene variations and prognosis in early-stage clear cell renal cell carcinoma显示文摘 | Francesca Lessi Chiara Maria Mazzanti Sara Tomei Claudio Cristofano Andrea Minervini Michele Menicagli Alessandro Apollo Lorenzo Masieri Paola Collecchi Riccardo Minervini Marco Carini Generoso Bevilacqua | 2014 | Medical Oncology2014，，3： | 2 |
| 3 | Simple Enucleation Versus Radical Nephrectomy in the Treatment of pT1a and pT1b Renal Cell Carcinoma显示文摘 | Andrea Minervini Sergio Serni Agostino Tuccio Giampaolo Siena Gianni Vittori Lorenzo Masieri Saverio Giancane Michele Lanciotti Saba Khorrami Alberto Lapini Marco Carini | 2012 | Annals of Surgical Oncology2012，，2： | 1 |
| 4 | Simple Enucleation is Equivalent to Traditional Partial Nephrectomy for Renal Cell Carcinoma: Results of a Nonrandomized, Retrospective, Comparative Study显示文摘 | Andrea Minervini Vincenzo Ficarra Francesco Rocco Alessandro Antonelli Roberto Bertini Giorgio Carmignani Sergio Cosciani Cunico Dario Fontana Nicola Longo Giuseppe Martorana Vincenzo Mirone Giuseppe Morgia Giacomo Novara Marco Roscigno Riccardo Schiavina | 2011 | The Journal of Urology2011，，5： | 1 |
| 5 | Histopathologic Analysis of Peritumoral Pseudocapsule and Surgical Margin Status after Tumor Enucleation for Renal Cell Carcinoma显示文摘 | Andrea Minervini Claudio di Cristofano Alberto Lapini Marco Marchi Federico Lanzi Gianluca Giubilei Nicola Tosi Agostino Tuccio Massimiliano Mancini Carlo della Rocca Sergio Serni Generoso Bevilacqua Marco Carini | 2008 | European Urology2008，，6： | 1 |
| 6 | PROGRESSION AND LONG-TERM SURVIVAL AFTER SIMPLE ENUCLEATION FOR THE ELECTIVE TREATMENT OF RENAL CELL CARCINOMA: EXPERIENCE IN 107 PATIENTS显示文摘 | ALBERTO LAPINI SERGIO SERNI ANDREA MINERVINI LORENZO MASIERI MARCO CARINI | 2005 | The Journal of Urology2005，，1： | 1 |
| 7 | Open versus laparoscopic partial nephrectomy for clinical T1a renal masses: a matched-pair comparison of 280 patients with TRIFECTA outcomes (RECORd Project)显示文摘 | Andrea Minervini Giampaolo Siena Alessandro Antonelli Giampaolo Bianchi Aldo Massimo Bocciardi Sergio Cosciani Cunico Vincenzo Ficarra Cristian Fiori Ferdinando Fusco Andrea Mari Giuseppe Martorana Mauro Medica Vincenzo Mirone Giuseppe Morgia Francesco Po | 2014 | World Journal of Urology2014，，1： | 1 |
| 8 | The use of pre-contoured plates in the treatment of C2–C3 fractures of the distal humerus: clinical experience显示文摘 | Andrea Celli Maria Teresa Donini Claudio Minervini | 2008 | La Chirurgia degli Organi di Movimento2008，，2： | 1 |
| 9 | VHL and HIF-1α: gene variations and prognosis in early-stage clear cell renal cell carcinoma显示文摘 | Francesca Lessi Chiara Maria Mazzanti Sara Tomei Claudio Cristofano Andrea Minervini Michele Menicagli Alessandro Apollo Lorenzo Masieri Paola Collecchi Riccardo Minervini Marco Carini Generoso Bevilacqua | 2014 | Medical Oncology2014，，3： | 1 |
| 10 | Robotic approach with neoadjuvant chemotherapy in adult Wilms’ tumor: A feasibility study report and a systematic review of the literature显示文摘Objective:The incidence of Wilms’tumor(WT)among adult individuals accounts for less than 1%of kidney cancer cases,with a prognosis usually less favorable when compared to younger individuals and an overall survival rate of 70%for the adult patients versus 90%for the pediatric cases.The diagnosis and treatment of WT are complex in the preoperative setting;neoadjuvant chemotherapy(NAC)or robotic surgery has rarely been described.This study aimed to review the literature of robotic surgery in WT and report the first adult WT management using both NAC and robotic strategy.Methods:We reported a case of WT managed in a multidisciplinary setting.Furthermore,according to Preferred Reporting Items for Systematic reviews and Meta-Analyses recommendations,a systematic review of the literature until August 2020 of WT treated with a robotic approach was carried out.Results:A 33-year-old female had a diagnosis of WT.She was scheduled to NAC,and according to the clinical and radiological response to a robotic radical nephrectomy with aortic lymph nodes dissection,she was managed with no intraoperative rupture,a favorable surgical outcome,and a follow-up of 25 months,which did not show any recurrence.The systematic review identified a total number of 230 cases of minimally invasive surgery reported in the literature for WT.Of these,approximately 15 patients were carried out using robotic surgery in adolescents while none in adults.Moreover,NAC has not been administered before minimally invasive surgery in adults up until now.Conclusion:WT is a rare condition in adults with only a few cases treated with either NAC or minimally invasive approach so far.The advantage of NAC followed by the robotic approach could lead to favorable outcomes in this complex scenario.Notwithstanding,additional cases of adult WT need to be identified and investigated to improve the oncological outcome. | Simone Sforza Valeria Emma Palmieri Maria Rosaria Raspollini Giandomenico Roviello Alberto Mantovani Umberto Basso Maria Carmen Affinita Alberto D’Angelo Lorenzo Antonuzzo Marco Carini Andrea Minervini Lorenzo Masieri | 2023 | Asian Journal of Urology2023，10，2： | 0 |
| 11 | Morbidity and psychological impact of prostate biopsy: the future calls for a change显示文摘当前 transrectal 指导超声的前列腺活体检视( TRUS-Bx )是最普通的 urological 过程之一,在经历 TRUS-Bx 的病人之中在欧洲和统一 States.1 每年与超过100万表现了,约三分之一个将收到前列腺癌症( PCa )的诊断,当三分之二在起始的活体检视上收到否定结果时。否定活体检视病人在 1 年维持12%的重复活体检视的估计的风险并且38%在 5 years.2 标准 TRUS-Bx 是可能的系统地错过重要肿瘤,特别地在 gland.3 的前面、顶端的部分,在下一十年的泌尿科医师的一个关键目的是增加过程的精确性并且避免不恰当的活体检视的使用。 | Andrea Minervini Gianni Vittori Giampaolo Siena Marco Carini | 2014 | Asian Journal of Andrology2014，16，3： | 0 |
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