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| 1 | Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle显示文摘The estimates of global incidence and prevalence of non-alcoholic fatty liver disease(NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major risk factors for NAFLD; interestingly, in the last years a growing body of evidence tended to support a novel mechanistic perspective, in which the liver is at the center of a complex interplay involving organs and systems, other than adipose tissue and glucose homeostasis. Bone and the skeletal muscle are fat- free tissues which appeared to be independently associated with NAFLD in several cross-sectional studies. The deterioration of bone mineral density and lean body mass, leading to osteoporosis and sarcopenia, respectively, are age-related processes. The prevalence of NAFLD also increases with age. Beyond physiological aging, the three conditions share some common underlying mechanisms, and their elucidations could be of paramount importance to design more effective treatment strategies for the management of NAFLD. In this review, we provide an overview on epidemiological data as well as on potential contributors to the connections of NAFLD with bone and skeletal muscle. | Eleonora Poggiogalle Lorenzo Maria Donini Andrea Lenzi Claudio Chiesa Lucia Pacifico | 2017 | World Journal of Gastroenterology2017，23，10： | 7 |
| 2 | Hepatic metastases from gastric cancer:A surgical perspective显示文摘Management of patients with hepatic metastases as the sole metastatic site at diagnosis of gastric cancer(synchronous setting) or detected during follow-up(metachronous) is controversial. The prevailing attitude in these cases is passive, leading to surgical palliation and, possibly, to chemotherapy. Authors focused this editorial in order to promote a more pragmatic attitude. They stress the importance of recognizing the good candidates to curative surgery of both gastric cancer and hepatic metastases(synchronous setting) or hepatic disease alone(metachronous disease) from those who will not benefit from surgical therapy. In fact, in adequately selected subgroup of patients surgery, especially if integrated in multimodal therapeutic strategies, may achieve unexpected 5-year survival rates, ranging from 10% to 40%. The critical revision of the literature suggests that some simple clinical criteria exist that may be effectively employed in patients selection. These are mainly related to the gastric cancer(factors T, N, G) and to the extent of hepatic involvement(factor H). Upon these criteria it is possible to adequately select about 50% of cases. In the remaining 50% of cases a critical discussion on a case-by-case basis is recommended, considering that among these patients some potential long-survivors exist, that survival is strictly influenced by the ablation of the tumor bulk and by multimodality treatments including chemotherapy and that in expert institutions this kind of surgery is performed with very low mortality and morbidity rates. | Guido Alberto Massimo Tiberio Franco Roviello Annibale Donini Giovanni de Manzoni | 2015 | World Journal of Gastroenterology2015，21，41： | 2 |
| 3 | Indirect calorimetry in obese female subjects: Factors influencing the resting metabolic rate显示文摘AIM: To evaluate selected factors influencing resting energy expenditure(REE) in obese female subjects.METHODS: Seventy seven 61 obese Caucasian women [mean age of 52.93 ± 13.45 years, and mean body mass index(BMI) of 41.78 ± 11.54 kg/m2] were enrolled; measurements of resting metabolic rate(RMR) by a ventilated, open-circuit system, indirect calorimeter were performed after an overnight fast. Body composition as well as medications, physical parameters, blood samples, disease pattern, and smoking were considered. RESULTS: RMR was significantly associated with body weight(r = 0.732, P < 0.001), body height(r = 0.401,P = 0.008), BMI(r = 0.504, P < 0.001), waist circumference(r = 0.602, P < 0.001), mid-upper arm circumference(r = 0.417, P = 0.006), mid-upper arm muscle circumference(r = 0.344, P = 0.028), total body water(r = 0.339, P = 0.035), body temperature(r = 0.409, P = 0.007), smoking(P = 0.031), serum T4 levels(r = 0.331, P = 0.036), obstructive sleep apnoea syndrome(OSAS; P = 0.023), impaired glucose tolerance(IGT; P = 0.017) and impaired glycaemic status, including hyperinsulinism, IGT and diabetes mellitus(P = 0.003).CONCLUSION: Future research should be prompted to optimize the procedure of indirect calorimetry to achieve clinical benefits in obese subjects. | Theresa Hagedorn Eleonora Poggiogalle Claudia Savina Cecilia Coletti Maddalena Paolini Luciano Scavone Barbara Neri Lorenzo Maria Donini | 2012 | World Journal of Experimental Medicine2012，2，3： | 2 |
| 4 | Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia显示文摘 | Roger A. Fielding Bruno Vellas William J. Evans Shalender Bhasin John E. Morley Anne B. Newman Gabor Abellan van Kan Sandrine Andrieu Juergen Bauer Denis Breuille Tommy Cederholm Julie Chandler Capucine De Meynard Lorenzo Donini Tamara Harris Aimo Kannt F | 2011 | Journal of the American Medical Directors Association2011，，4： | 2 |
| 5 | Malignant ascites: pathophysiology and treatment显示文摘 | Emanuel Cavazzoni Walter Bugiantella Luigina Graziosi Maria Silvia Franceschini Annibale Donini | 2013 | International Journal of Clinical Oncology2013，，1： | 2 |
| 6 | Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes:a new perspective for an old disease显示文摘 | PATRITI A FACCHIANO E DONINI A | 2004 | Ann Surg2004，240，2： | 1 |
| 7 | Temperament,character,and attachment patterns in borderline personality disorder显示文摘 | Fossati A Donati D Donini M Novella L Bagnato M Maffei C | 2001 | J Personal Disord2001，15，： | 1 |
| 8 | A microsatellite marker based linkage map of tobacco 显示文摘 | Bindler G Hoeven R Gunduz I Plieske J Ganal M Rossi L Gadani F Donini P | 2007 | Theor Appl Genet2007，114，： | 1 |
| 9 | Induction of Th1/Th17 immune response by Mycobacterium tuberculosis : role of dectin-1, Mannose Receptor, and DC-SIGN显示文摘 | Zenaro E Donini M Dusi S | 2009 | J Leukoc Biol2009，86，6： | 1 |
| 10 | Laparoscopie splenectomy in the management of hematological disease 显示文摘 | Terrosu G Donini A Silvestri F | 1995 | Haematologica1995，80，4： | 1 |
| 11 | Nutrition in the elderly: role of fiber 显示文摘 | Donini L M Savina C Cannella C | 2009 | Arch Gerontol Geriatr2009，417，1： | 1 |
| 12 | Elective transumbilical compared with standard laparoscopic cholecystectomy 显示文摘 | Bresadola F Pasqualucci A Donini A | 1999 | Eur J Surg1999，165，1： | 1 |
| 13 | Liberase HI enzyme versus colla-genase type P for porcine hepatocyte isolation 显示文摘 | Donini A Baccaranl U Lavaroni S | 2001 | Transplant Proc2001，33，12： | 1 |
| 14 | The use of pre- con- toured plates in the treatment of C2 - C3 fractures of the distal humerus: clinical experience 显示文摘 | Celli A Donini MT Minervini C | 2008 | Chir Organi Mov2008，91，2： | 1 |
| 15 | Effect of nutritional status on clinical outcome in a population of geriatric rehabilitation pa- tients显示文摘 | Donini LM De Bernardini L De Felice MR | 2004 | Aging Clin Exp Res2004，16，2： | 1 |
| 16 | A Randomized Study on 1-Week Versus 4-Week Prophylaxis for Venous Thromboembolism After Laparoscopic Surgery for Colorectal Cancer显示文摘 | Maria Cristina Vedovati Cecilia Becattini Fabio Rondelli Michela Boncompagni Giuseppe Camporese Ruben Balzarotti Enrico Mariani Otello Flamini Salvatore Pucciarelli Annibale Donini Giancarlo Agnelli | 2014 | Annals of Surgery2014，，： | 1 |
| 17 | Retrotransposon characterisation and fingerprinting of apple clones by S-SAP markers显示文摘 | VENTURI S DONDINI L DONINI P SANSAVINI S | 2005 | Theor Appl Genet2005，112，： | 1 |
| 18 | Combining mutations for the two homoeologous pairing suppressor genes Ph1 and Ph2 in common wheat and in hybrids with alien Triticeae显示文摘 | Ceoloni C Donini P | 1993 | Genome1993，36，2： | 1 |
| 19 | Strict reaction and substrate specificity of AGXT2L1,the human O-phosphoethanolamine phospho-lyase显示文摘 | Schiroli D Cirrincione S Donini S | 2013 | IUBMB Life2013，65，7： | 1 |
| 20 | Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease显示文摘 | Patriti A Facehiano E Donini A | 2004 | Ann Surg2004，240，2： | 1 |
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