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| 1 | Ammonia-oxidizing archaea and bacteria are structured by geography in biological soil crusts across North American arid lands显示文摘Introduction:Biological soil crusts(BSCs)can dominate surface cover in dry lands worldwide,playing an integral role in arid land biogeochemistry,particularly in N fertilization through fixation and cycling.Nitrification is a characteristic and universal N transformation in BSCs that becomes important for the export of N beyond the microscopic bounds of the crust itself.The contribution of ammonia-oxidizing bacteria(AOB)in BSCs has been shown,but the role and extent of the recently discovered ammonia-oxidizing archaea(AOA)have not.Methods:We sampled various types of crusts in four desert regions across the western United States and characterized the composition and size of ammonia-oxidizing communities using clone libraries and quantitative PCR targeting the amoA gene,which codes for the ammonia monooxygenase enzyme,universally present in ammonia-oxidizing microbes.Results:All archaeal amoA sequences retrieved from BSCs belonged to the Thaumarchaeota(Nitrososphaera associated Group I.1b).Sequences from the Sonoran Desert,Colorado Plateau,and Great Basin were indistinguishable from each other but distinct from those of the Chihuahuan Desert.Based on amoA gene abundances,archaeal and bacterial ammonia oxidizers were ubiquitous in our survey,but the ratios of archaeal to bacterial ammonia oxidizers shifted from bacterially dominated in northern,cooler deserts to archaeally dominated in southern,warmer deserts.Conclusions:Archaea are shown to be potentially important biogeochemical agents of biological soil crust N cycling.Conditions associated with different types of BSCs and biogeographical factors reveal a niche differentiation between AOA and AOB,possibly driven by temperature. | Yevgeniy Marusenko Scott T Bates Ian Anderson Shannon L Johnson Tanya Soule Ferran Garcia-Pichel | 2013 | Ecological Processes2013，2，1： | 4 |
| 2 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 3 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 4 | 低浓度胰岛素样生长因子Ⅱ可以预报正常体重2型糖尿病患者的体重增加显示文摘 | Heald AH Karvestedt L Anderson SG 菅鑫妍 | 2006 | 中国处方药2006，5，6： | 3 |
| 5 | Evaluation of C-reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction显示文摘 | Jeffrey L Anderson John F Carlquist Joseph B Muhlestein Benjamin D Horne Sidney P Elmer | 1998 | Journal of the American College of Cardiology1998，，1： | 2 |
| 6 | Protein kinase B kinases that mediate phosphatidy linositol 3,4,5-trisphosphate-dependent activation of protein kinase B显示文摘 | Stephens L Anderson K Stokoe D | | 0，，： | 2 |
| 7 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 8 | 梅毒IgA快速检测试剂诊断早期现症梅毒的应用性评估显示文摘目的评估Burnet研究所自制的IgA快速检测试剂(POC)对早期梅毒的诊断性能。方法利用性病中心参比实验室库存的455份血清标本进行梅毒IgA-POC应用性评估,标本根据梅毒螺旋体血球凝集试验(TPHA)、快速血浆反应素环状卡片试验(RPR)及IgM酶联免疫吸附试验(IgM-ELISA)结果分为未感染组、既往感染组和早期现症组。对3组标本进行IgA—POC盲样检测,评估其对现症梅毒的诊断能力。结果IgA—POC对早期现症组的诊断灵敏度为92.6%(147/163),对既往感染组的排除诊断特异性为72.22%(104/144);对未感染的排除诊断特异性为97.97%(145/148),总特异性为85.27%,达到了WHO对梅毒快速诊断试剂的最低要求。IgA—POC对早期现症梅毒诊断灵敏度高于IgM—ELISA(59.51%)(Z=6.88,P〈0.05),但其对既往感染的排除诊断特异性低于lgM-ELISA(98.61%)(Z=6.18,P〈0.05),两种方法对未感染的排除诊断特异性差异无统计学意义(Z=1.16,P=0.25)。结论IgA—POC对早期现症梅毒的发现能力较IgM—ELISA强,可以应用于早期现症梅毒的筛查。 | 韩燕 魏万惠 尹跃平 David Anderson 王红春 Mary L Garcia Huy Van 朱小宇 陈凯 陈祥生 | 2018 | 中华皮肤科杂志2018，51，5： | 2 |
| 9 | Epidemiological investigation of infectious hematopoietic necrosis virus in salt water net-pen reared Atlantic salmon in British Columbia, Canada显示文摘 | Sophie St-Hilaire Carl S Ribble Craig Stephen Eric Anderson Gael Kurath Michael L Kent | 2002 | Aquaculture2002，，1： | 2 |
| 10 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 11 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 12 | Murine model to study brain,behavior and immunity during hepatic encephalopathy显示文摘AIM:To propose an alternative model of hepatic encephalopathy(HE) in mice,resembling the human features of the disease.METHODS:Mice received two consecutive intraperitoneal injections of thioacetamide(TAA) at low dosage(300 mg/kg).Liver injury was assessed by serum transaminase levels(ALT) and liver histology(hematoxylin and eosin).Neutrophil infiltration was estimated by confocal liver intravital microscopy.Coagulopathy was evaluated using prolonged prothrombin and partial thromboplastin time.Hemodynamic parameters were measured through tail cuff.Ammonia levels were quantified in serum and brain samples.Electroencephalography(EEG) and psychomotor activity score were performed to show brain function.Brain edema was evaluated using magnetic resonance imaging.RESULTS:Mice submitted to the TAA regime developed massive liver injury,as shown by elevation of serum ALT levels and a high degree of liver necrosis.An intense hepatic neutrophil accumulation occurred in response to TAA-induced liver injury.This led to mice mortality and weight loss,which was associated with severe coagulopathy.Furthermore,TAA-treated mice presented with increased serum and cerebral levels of ammonia,in parallel with alterations in EEG spectrum and discrete brain edema,as shown by magnetic resonance imaging.In agreement with this,neuropsychomotor abnormalities ensued 36 h after TAA,fulfilling several HE features observed in humans.In this context of liver injury and neurological dysfunction,we observed lung inflammation and alterations in blood pressure and heart rate that were indicative of multiple organ dysfunction syndrome.CONCLUSION:In summary,we describe a new murine model of hepatic encephalopathy comprising multiple features of the disease in humans,which may provide new insights for treatment. | Lindisley Ferreira Gomides Pedro Elias Marques Bruno Engler Faleiros Rafaela Vaz Pereira Sylvia Stella Amaral Thais Reis Lage Gustavo Henrique Souza Resende Patricia Alves Maia Guidine Giselle Foureaux Fabíola Mara Ribeiro Fabiana Paiva Martins Marco Antonio Peliky Fontes Anderson José Ferreira Remo Castro Russo Mauro Martins Teixeira Márcio Flávio Moraes Antonio Lúcio Teixeira Gustavo Batista Menezes | 2014 | World Journal of Hepatology2014，6，4： | 2 |
| 13 | Reduced striatal volumes in Parkinson’s disease:a magnetic resonance imaging study显示文摘Background:The presence and extent of structural changes in the brain as a consequence of Parkinson’s disease(PD)is still poorly understood.Methods:High-resolution 3-tesla T1-weighted structural magnetic resonance images in sixty-five PD and 27 age-matched healthy control participants were examined.Putamen,caudate,and intracranial volumes were manually traced in the axial plane of 3D reconstructed images.Striatal nuclei volumes were normalized to intracranial volume for statistical comparison.Disease status was assessed using the Unified Parkinson’s Disease Rating Scale and Hoehn and Yahr scale.Cognitive status was assessed using global status tests and detailed neuropsychological testing.Results:Both caudate and putamen volumes were smaller in PD brains compared to controls after adjusting for age and gender.Caudate volumes were reduced by 11%(p=0.001)and putamen volumes by 8.1%(p=0.025).PD striatal volumes were not found to be significantly correlated with cognitive or motor decline.Conclusion:Small,but significant reductions in the volume of both the caudate and putamen occur in PD brains.These reductions are independent of the effects of age and gender,however the relation of these reductions to the functional loss of dopamine,which is characteristic of PD,remains unclear. | Toni L Pitcher Tracy R Melzer Michael R MacAskill Charlotte F Graham Leslie Livingston Ross J Keenan Richard Watts John C Dalrymple-Alford Tim J Anderson | 2012 | Translational Neurodegeneration2012，1，1： | 2 |
| 14 | Diet and fecal lipids following cholecystectomy in men显示文摘 | BRYDON W G ROSS M C L ANDERSON J R | 1982 | Digestion1982，25，： | 1 |
| 15 | GENI design principles 显示文摘 | Peterson L Anderson T Blumenthal D | 2006 | IEEE Computer2006，39，9： | 1 |
| 16 | Evaluation of constructed and natural soil macropores using X-ray computed tomography 显示文摘 | Peyton R L Gantzer C J | 1990 | Geoderma1990，46，： | 1 |
| 17 | Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological evidents for Chlamydia pneumoniae infection: The azithromycin in coronary artery disease elimination of myocardial infection with chlamydia (ACADEMIC) study显示文摘 | Muhlstein J B Carlquist J | 1999 | Circulation1999，99，： | 1 |
| 18 | Preliminary Statistical Analysis of Data from the Ontario Spectial Rope Tests on Mine-hoist Wire Ropes显示文摘 | Rice R C Anderson G L | 1984 | CIIVI Buttetin1984，77，871： | 1 |
| 19 | Gemaination as a determinant of seedling distributions among natural substrates in Picea engelmannii(Pinaceae)and Abies(Pimiceae)显示文摘 | WINTERTON A J | 1996 | Am J Bot1996，83，： | 1 |
| 20 | Gravitational Constraints on the Internal Structure of Ganymede显示文摘 | LAU E L SJOGREN W L, | 1996 | Nature1996，384，6609： | 1 |
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