|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors显示文摘Long non-coding RNAs(lncRNAs)are members of the non-protein coding RNA family longer than 200 nucleotides.They participate in the regulation of gene and protein expression influencing apoptosis,cell proliferation and immune responses,thereby playing a critical role in the development and progression of various cancers,including colorectal cancer(CRC).As CRC is one of the most frequently diagnosed malignancies worldwide with high mortality,its screening and early detection are crucial,so the identification of disease-specific biomarkers is necessary.LncRNAs are promising candidates as they are involved in carcinogenesis,and certain lncRNAs(e.g.,CCAT1,CRNDE,CRCAL1-4)show altered expression in adenomas,making them potential early diagnostic markers.In addition to being useful as tissue-specific markers,analysis of circulating lncRNAs(e.g.,CCAT1,CCAT2,BLACAT1,CRNDE,NEAT1,UCA1)in peripheral blood offers the possibility to establish minimally invasive,liquid biopsy-based diagnostic tests.This review article aims to describe the origin,structure,and functions of lncRNAs and to discuss their contribution to CRC development.Moreover,our purpose is to summarise lncRNAs showing altered expression levels during tumor formation in both colon tissue and plasma/serum samples and to demonstrate their clinical implications as diagnostic or prognostic biomarkers for CRC. | Orsolya Galamb Barbara K Barták Alexandra Kalmár Zsófia B Nagy Krisztina A Szigeti Zsolt Tulassay Peter Igaz Béla Molnár | 2019 | World Journal of Gastroenterology2019，25，34： | 18 |
| 2 | 评估清晨或夜晚服用降压药对24h动态血压的影响:清晨或夜间服用降压药的希腊英国联合研究显示文摘观察数据显示,临床血压水平与随后的主要不良心血管事件之间存在强烈的线性关系。然而,动态血压监测显示,夜间血压水平比24h或白天血压水平更能预测主要的不良心血管事件。此外,夜间与白天的血压比值和杓型状态也是心血管结局的重要独立预测因素。这些发现可能对抗高血压药物的最佳给药时间有影响,一些研究表明,夜晚服用降压药可能较白天服药减少心血管事件。 | Poulter NR Savopoulos C Anjum A Apostolopoulou M Chapman N Cross M Falaschetti E Fotiadis S James RM Kanellos I Szigeti M Thom S Sever P Thompson D Hatzitolios AI 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，10： | 7 |
| 3 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 4 | Why momentum width matters for atom interferometry with Bragg pulses显示文摘 | S S Szigeti J E Debs J J Hope N P Robins J D Close | 2012 | New Journal of Physics2012，，2： | 2 |
| 5 | Interface phenomena in processing of ceramic reinforced amorphous metal composites显示文摘 | G Kaptay P Barczy F Szigeti | 1996 | Journal of Non-Crystalline Solids1996，，2： | 1 |
| 6 | Delayed Cardioprotective Effects of Exercise in Dogs are Aminoguanidine Sensitive: Possible Involvement of Nitric Oxide显示文摘 | BABAI L SZIGETI Z PARRATT J R | 2002 | Clin Sci2002，102，： | 1 |
| 7 | Preliminary study of TIP47 as a possible new biomarker of cervical dysplasia and invasive carcinoma显示文摘 | Szigeti A Minik O Hocsak E | 2009 | Anticancer Res2009，29，2： | 1 |
| 8 | Management of posterior segment IOFBs显示文摘 | Szigeti Z | 2001 | Ophthalmology2001，08，3： | 1 |
| 9 | Centralizers in endomorphism rings显示文摘 | Drensky V Szigeti J van Wyk L | 2010 | J Algebra2010，324，12： | 1 |
| 10 | Nicotine interferes with purinergic signaling in smooth muscle cells isolated from uri- nary bladders of patients with lower urinary tract symptoms 显示文摘 | Jenes A Szigeti GP Ruzsnavszky F | 2013 | Gen Physiol Biophys2013，32，： | 1 |
| 11 | 显示文摘 | Janosi S Szigeti G Ratz F | 2001 | Vet Q2001，23，2： | 1 |
| 12 | Prenatal sonographic findings in 207 fetuses with trisomy 21显示文摘 | Papp C Bn Z Szigeti Z | 2007 | Eur J Obstet Gynecol Reprod Biol2007，133，2： | 1 |
| 13 | Management Of posterior segment IOFBs显示文摘 | Szigeti Z | 2001 | Ophthalmology2001，108，3： | 1 |
| 14 | Impact of iron supply on the kinetics of recovery of photosynthesis in Cd-stressed Poplar (Populus glauca) 显示文摘 | Solti A Gaspar L Szigeti Z | 2008 | Annals of botany2008，102，5： | 1 |
| 15 | Charcot-Marie-Tooth disease and related hereditary polyneuropathies: molecular diagnostics determine aspects of medical management 显示文摘 | Szigeti K Garcia CA Lupski JR | 2006 | Genet Med2006，8，2： | 1 |
| 16 | Influence of a Spirulina pla tens is biomass on the microflora of fermented ABT milks during storage (R 1)显示文摘 | VARGA L SZIGETI J KOVACS R | 2002 | J Dairy Science2002，85，5： | 1 |
| 17 | Arytenoid dislocation with lighted stylet intubation: case report and retrospective review 显示文摘 | Szigeti CL Baeuerle JJ Mongan PD | 1994 | Anesth Analg1994，78，1： | 1 |
| 18 | Characterization of a i -dependent current in human atrial and ventricular ventricular myocytes in the absence of Na^+ and K^+ 显示文摘 | Koster OF Szigeti GP Beuckelmann DJ | 1999 | Cardiovasc Res1999，41，： | 1 |
| 19 | Delayed cardioprotective effects of exercise in dogs are aminoguanidine sensitive:possible involvement of nitric oxide显示文摘 | Babai L Szigeti Z Parratt JR | 2002 | Clin Sci2002，102，4： | 1 |
| 20 | A new type polyvinyl alcohol by improved with urea and its ramification显示文摘 | Szigeti L Tanner R D | 1999 | Photopolymer Science Technology1999，12，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员