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| 1 | 自发性脑出血诊疗指南--美国心脏协会/美国卒中协会的健康职业者指南显示文摘在世界范围内,自发性、非创伤性脑出血(intracranial hemorrhage,ICH)仍然是致死、致残的重要原因。虽然在临床研究及治疗指南的临床证据方面,ICH一直落后于缺血性卒中和动脉瘤性蛛网膜下腔出血,但在过去的10年内有了长足的增长。基于人群的研究发现,出血量较小的ICH患者几乎均能通过良好的内科治疗而存活[1],提示良好的内科治疗很可能直接影响ICH患者的残疾率。本指南的目的是,纳入最新临床研究的中期结果,并更新2010年版指南[2],向临床医师强调,其管理对ICH患者结局有着重要影响,并为临床管理提供相应的循证医学证据。为保证本指南的简洁和实用性,ICH的背景及流行病学均被省略,仅提供参考文献供查阅[1,3-4]。 | Hemphill JC Ⅲ Greenberg SM Anderson CS 文婉玲 于瀛 黄清海 | 2015 | 中国脑血管病杂志2015，12，9： | 85 |
| 2 | 缺血性脑卒中和出血性脑卒中患者发病前后血压的变化显示文摘《中国高血压防治指南2010》指出,急性脑卒中的血压处理缺乏足够的临床试验证据,参考建议如下:急性脑卒中溶栓前血压应控制在<185/110mm Hg(1mm Hg=0.133kPa)。对急性缺血性脑卒中发病24h内血压升高的患者应谨慎处理,收缩压≥180mm Hg或舒张压≥100mm Hg或伴有严重心功能不全、主动脉夹层、高血压脑病者,一般不予降压。降压的合理目标是24h内血压降低约15%。有高血压病史且正在服用降压药物者,如神经功能平稳,可于脑卒中发病后24h开始使用降压药物。因此,了解脑卒中患者发病前后的血压情况对临床治疗有重要的意义。Fischer等研究者探讨缺血性脑卒中和出血性脑卒中患者发病前后血压的变化情况。结果表明,缺血性脑卒中患者发病后首次测量的收缩压低于出血性脑卒中。与发病前比较,缺血性脑卒中发病后收缩压略升高(约10.6mm Hg),24h内轻度降低(约13.6mm Hg);而出血性脑卒中发病后,收缩压明显升高(约40.7mm Hg),24h内明显下降(约41.1mm Hg)。出血性脑卒中发病前几天及几周的平均收缩压逐渐增加,而缺血性脑卒中无明显变化。出血性脑卒中患者发病3h内的最高收缩压比发病前高50.0 mm Hg,而缺血性脑卒中则低5.2mm Hg。综上所述,与发病前比较,出血性脑卒中发病后收缩压升高,而缺血性脑卒中无明显变化。 | Fischer U Cooney MT Bull LM Silver LE Chalmers J Anderson CS Mehta Z Rothwell PM 林东杰 叶鹏 | 2014 | 中华高血压杂志2014，22，4： | 13 |
| 3 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 4 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 5 | Activeand passive smoking and the risk of subarachnoid hemorrhage: an international population-based casecontrol study显示文摘 | Anderson CS Feigin V Bennett D | 2004 | Stroke2004，35，： | 1 |
| 6 | Mirror reflectometer based on optical cavity decay time显示文摘 | Anderson D Z FrisehJ C Masser CS | 1984 | ApplOpt1984，23，8： | 1 |
| 7 | Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial显示文摘 | Anderson CS Huang Y Wang JG | 2008 | Lancet Neurol2008，7，5： | 1 |
| 8 | Heahhrelatedquality of life among long term survivors of stroke显示文摘 | Haekett ML DuncanJR Anderson CS | 2000 | Stroke2000，312，2： | 1 |
| 9 | Intensive blood pressure reduction in acute cerebral hemorrhage trial (INTERACT) : a ran- domised pilottrial显示文摘 | Anderson CS Huang Y Wang JG | 2008 | Lancet Neurol2008，7，： | 1 |
| 10 | Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial显示文摘 | Anderson CS Huang Y Wang JG | 2008 | Lancet Neuro12008，7，5： | 1 |
| 11 | Intensive blood pressure reduction in acute cerebral haemorrhage trial ( INTERACT ) : a randomised pilot trial 显示文摘 | Anderson CS Huang Y Wang JG | 2008 | Lancet Neurol2008，7，5： | 1 |
| 12 | Improved survival after stroke: Is admission to hospital the major explanation? Trend analyses of the Auckland Regional Community Stroke Studies 显示文摘 | Carter KN Anderson CS Hackett ML | 2007 | Cerebrovasc Dis2007，23，2： | 1 |
| 13 | Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars 显示文摘 | Cavanagh CS Chao S Wang BE Huang BE Stephen S Kiani S Forrest K Saintenac C Brown-Guedira GL Akhunova A See D Bai G Pumphrey M Tomar L Wong D Kong S Reynolds M da Silva ML Bockelman H Talbert L Anderson JA Dreisigacker S Baenziger S Carter A Korzun V Morrell PL Dubcovsky J Morell MK Sorrells ME Hayden MJ Akhunov E | 2013 | PNAS2013，110，： | 1 |
| 14 | Intensive blood pres- sure reduction in acute cerebral haemorrhage trial (IN- TERACT) :a randomised pilot trial显示文摘 | Anderson CS Huang Y Wang JG | 2008 | Lancet Neurol2008，7，5： | 1 |
| 15 | Metal binding and oxidation of amyloid-beta within isolated senile plaque cores:Raman microscopic evidence显示文摘 | Dong J Atwood CS Anderson VE | 2003 | Biochemistry2003，42，： | 1 |
| 16 | 显示文摘 | Huang CS Anderson ME Meister A | 1993 | J Biolchem1993，268，20： | 1 |
| 17 | Ascertaining the incidence of stroke experience from the Perth Community Stroke Study 1989 ~ 1990显示文摘 | Jamrozid KD Burvill PW | 1993 | Med J Aust1993，158，： | 1 |
| 18 | NGF depletion reduces ipsilateral trigeminal satellite cell reactions after inferior alveolar nerve injury in adult rats显示文摘 | Barthfeld CS Byers MR | 1998 | Neurol1998，150，2： | 1 |
| 19 | Medical management of acute intracerebral hemorrhage显示文摘 | Anderson CS | 2009 | Curr Opin Crit Care2009，15，2： | 1 |
| 20 | Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT) 显示文摘 | Anderson CS Huang Y Arima H | 2010 | Stroke2010，41，2： | 1 |
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