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| 1 | Meta‐analysis: the safety and efficacy of vaptans (tolvaptan, satavaptan and lixivaptan) in cirrhosis with ascites or hyponatraemia显示文摘 | E. Dahl L. L. Gluud N. Kimer A. Krag | 2012 | Aliment Pharmacol Ther2012，，7： | 3 |
| 2 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 3 | Allocation of patients with liver cirrhosis and organ failure to intensive care: Systematic review and a proposal for clinical practice显示文摘AIM: To propose an allocation system of patients with liver cirrhosis to intensive care unit(ICU), and developed a decision tool for clinical practice. METHODS: A systematic review of the literature was performed in Pub Med, MEDLINE and EMBASE databases. The search includes studies on hospitalized patients with cirrhosis and organ failure, or acute on chronic liver failure and/or intensive care therapy. RESULTS: The initial search identified 660 potentially relevant articles. Ultimately, five articles were selected; two cohort studies and three reviews were found eligible. The literature on this topic is scarce and no studies specifically address allocation of patients with liver cirrhosis to ICU. Throughout the literature, there is consensus that selection criteria for ICU admission should be developed and validated for this group of patients and multidisciplinary approach is mandatory. Based on current available data we developed an algorithm, to determine if a patient is candidate to intensive care if needed, based on three scoring systems: premorbid Child-Pugh Score, Model of End stage Liver Disease score and the liver specific Sequential Organ Failure Assessment score.CONCLUSION: There are no established systems for allocation of patients with liver cirrhosis to the ICU and no evidence-based recommendations can be made. | Katrine Prier Lindvig Ane Sogaard Teisner Jens Kjeldsen Thomas Strom Palle Toft Valentin Furhmann Aleksander Krag | 2015 | World Journal of Gastroenterology2015，21，29： | 3 |
| 4 | Biomechanical characteristics of the human anterior lens capsule in relation to age 显示文摘 | Krag S Olsen T Andreassent TA | 1997 | Invest Ophthalmol Vis Sci1997，38，： | 2 |
| 5 | 无创筛查酒精相关性肝纤维化的成本效果分析显示文摘【据《Hepatology》2019年10月报道】题:无创筛查酒精相关性肝纤维化的成本效果分析(作者Asphaug L等)酒精相关性肝病常常难以被发现,直到终末期出现肝功能失代偿表现时才被引起注意。该研究旨在分析针对进展期酒精相关性肝纤维化的经济、高效的无创筛查方法的成本效果。来自挪威的Asphaug等进行了一项现实世界数据的研究,作者从丹麦多中心招募了具有肝活检病理结果的大量饮酒者,评价一级诊疗中心采用的4种筛查策略:(1)传统的肝功能化验,如果结果阳性则进一步完善腹部超声;(2)肝纤维化血清学标志物:强化的肝纤维化(ELF)试验,如果结果阳性则进一步完善肝硬度(LSM)检查;(3)三级策略:在进行第2种策略前进行Forns索引(根据年龄、血小板计数、GGT、胆固醇水平得到的无创预测公式);(4)直接进行LSM检查。应用决策树和Markov联合模型进一步评价短期结果(每项准确诊断的成本)和长期结果[质量调整生命年(QALYs)]。 | 周胜云 段志辉 ASPHAUG L THIELE M KRAG A | 2020 | 临床肝胆病杂志2020，36，1： | 2 |
| 6 | Safety and efficacy of Profermin~to induce remission in ulcerative colitis显示文摘AIM:To test the efficacy and safety of Profermin in inducing remission in patients with active ulcerative colitis(UC).METHODS:The study included 39 patients with mild to moderate UC defined as a Simple Clinical Colitis Activity Index(SCCAI)>4 and<12(median:7.5),who were treated open-label with Profermintwice daily for 24 wk.Daily SCCAI was reported observer blinded via the Internet.RESULTS:In an intention to treat(ITT)analysis,the mean reduction in SCCAI score was 56.5%.Of the 39 patients,24(62%)reached the primary endpoint,which was proportion of patients with≥50%reduction in SCCAI.Our secondary endpoint,the proportion of patients in remission defined as SCCAI≤2.5,was in ITT analysis reached in 18 of the 39 patients(46%).In a repeated-measure regression analysis,the estimated mean reduction in score was 5.0 points(95%CI:4.1-5.9,P<0.001)and the estimated mean time taken to obtain half the reduction in score was 28 d(95%CI:26-30).There were no serious adverse events(AEs)or withdrawals due to AEs.Profermin was generally well tolerated.CONCLUSION:Profermin is safe and may be effective in inducing remission of active UC. | Aleksander Krag Hans Israelsen Bjrn von Ryberg Klaus K Andersen Flemming Bendtsen | 2012 | World Journal of Gastroenterology2012，18，15： | 2 |
| 7 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 8 | Combined effects of moderately elevated blood glucose and locally produced TGF-beta1 on glomerular morphology and renal collagen production 显示文摘 | Krag S Nyengaard JR Wogensen L | 2007 | Nephrol Dial Transplant2007，22，9： | 1 |
| 9 | Biomechanical characteristics of the human anterior lens capsule in relation to age 显示文摘 | Krag S Olsen T Andreassen T | 1997 | Invest Ophthalmol Vis Sci1997，38，： | 1 |
| 10 | Simulation-based study of the combined effect on cod-end size selection of turning meshes by 90° and reducing the number of meshes in the circumference for round fish显示文摘 | Herrmann B Priour D Krag L A | 2007 | Fish Res2007，84，2： | 1 |
| 11 | Effect of preload on load displacement curves of the lumbar spine显示文摘 | White AA Krag M Panjabi MM | 1977 | Orthop Clin North AM1977，8，1： | 1 |
| 12 | SentineJ lymph node- why study it:implications of the B- 32 study显示文摘 | Harlow SP Krag DN | 2001 | Semin Surg Oncol2001，20，3： | 1 |
| 13 | Diagnosing instability显示文摘 | Pope MM Krag MH | 1992 | Clin OrthoP Rel Res1992，278，： | 1 |
| 14 | The sentinel node in breast cancer: a multicenter validation study 显示文摘 | KRAG D WEAVER D ASHIKGA T | 1998 | N Engl J Med1998，339，： | 1 |
| 15 | Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe显示文摘 | Krag DN Weaver DL Alex JC | 1993 | Surg-Oncol1993，2，6： | 1 |
| 16 | Sentinel - lymph - node resection compared with conventional axillary -lymph - node dissection in clinically node - negative patients with breast cancer: overall survival findings from the NSABP B -32 ran- domised phase 3 trial显示文摘 | KRAG D N ANDERSON S J JULIAN T B | 2010 | Lancet Oncol2010，11，10： | 1 |
| 17 | Surgical resection and radio- localization of the sentinel lymph node in breast cancer using a gamma probe显示文摘 | Krag DN Weaver DL Alex JC | 1993 | Surgoncol1993，2，6： | 1 |
| 18 | The sentinel node in breast cancer-a muhicenter validation study 显示文摘 | Krag DN Weaver D Ashikaga T | 1998 | N Engl J Med1998，399，14： | 1 |
| 19 | The sentinel node in breast cancer, a multicenter calidation study 显示文摘 | Krag D Weager D Askikaga T | 1998 | N Engl J Med1998，339，14： | 1 |
| 20 | Circadian intraocular pressure variation with beta-blockers显示文摘 | Krag S Andersen HB Sorensen T | 1999 | Acta Ophthalmol Scand1999，77，5： | 1 |
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