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| 1 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 2 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 3 | Indigenous plants and weeds on the Makhathini flats as refuge hosts to maintain bollworm population susceptibility to transgenic cotton (Bollgard)显示文摘 | Green W M De Billot M C Joffe T van Staden L Bennett-Nel A Du Toit C L N and van der Westhuizen L | | 0，，： | 1 |
| 4 | Hydroxyethylstarch or saline in intensive care显示文摘 | MYBURGH J A FINFER S BILLOT L | 2013 | N Engl J Med2013，368，8： | 1 |
| 5 | Modiccation of peptidoglycan precursors is a commonfeature of the low-level vancomycin-resistant VANB-type Enterococcus D366 and of the naturally glycopeptide-resistant species Lactobacillus casei,Pediococcus pentosacues,Leuconostoc mesenteroides,and Enterococcus gallinarum显示文摘 | Billot KD Gutmann L Sable S | 1994 | J Bacteriol1994，176，： | 1 |
| 6 | Managing blood glucose in critically ill patients with or without diabetes显示文摘 | Finfer S Billot L | 2013 | Crit Care2013，17，2： | 1 |
| 7 | Outcomes of unrelated cord blood transplantation in pediatric recipients 显示文摘 | Styczynski J Cheung YK Garvin J Savage DG Billote GB Harrison L | 2004 | Bone Marrow Transplant2004，34，2： | 1 |
| 8 | The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors显示文摘 | Watson M Roulston A B61ec L Billot X Marcellus R Bdard D | 2009 | Mol Cell Biol2009，29，： | 1 |
| 9 | Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes显示文摘 | Patel A MacMahon S Chalmers J Neal B Billot L Woodward M | | 0，，： | 1 |
| 10 | Reproducibility and sensitivity to change of 5 methods for scoring hand radiographic damage in patients with rheumatoid arthritis显示文摘 | Guillemin F Billot L Boini S | 2005 | J Rheumatol2005，32，5： | 1 |
| 11 | No benefit of flat head positioning in early moderate-severe acute ischaemic stroke: a HeadPoST study subgroup analysis显示文摘background Although the Head Positioning in acute Stroke Trial(HeadPoST)showed no effect of the flat head position(FP;vs sitting up head position(SUP))on functional outcome,we hypothesised that it could still offer benefits if commenced early in those with acute ischaemic stroke(AIS)of at least moderate severity.Methods Subgroup analysis of HeadPoST in participants with National Institutes of Health Stroke Scale(NIHSS)scores≥7,≥10 and≥14,randomised to FP or SUP<4.5 hours of AIS onset on functional outcomes defined by a shift in scores on the modified Rankin scale(mRS)and death/disability(mRS scores 3-6),and any cardiovascular serious adverse event.Logistic regression analyses were undertaken adjusted for study design and baseline risk factors.results There was no significant differential treatment effect in patient subgroups defined by increasing baseline NIHSS scores:adjusted OR and 95%CI for ordinal shift and binary(3-6)mRS scores:for NIHSS≥7(n=867)0.92(0.67 to 1.25)and 0.74(0.52 to 1.04);NIHSS≥10(n=606)0.80(0.58 to 1.10)and 0.77(0.49 to 1.19);NIHSS≥14(n=378)0.82(0.54 to 1.24)and 1.22(0.69 to 2.14).Conclusions Early FP had no significant effect in patients with moderate-severe AIS. | Alejandro M Brunser Menglu Ouyang Hisatomi Arima Pablo M Lavados Thompson Robinson Paula Munoz-Venturelli Veronica V Olavarria Laurent Billot Marre L Hackett Lili Song Sandy Middleton Octavio Pontes-Neto Tsong-Hai Lee Caroline Watkins Craig S Anderson | 2020 | Stroke & Vascular Neurology2020，5，4： | 0 |
| 12 | 超低剂量四联疗法治疗高血压的成本效益显示文摘确定含有厄贝沙坦37.5 mg、氨氯地平1.25 mg、吲达帕胺0.625 mg和比索洛尔2.5 mg的四药联用与厄贝沙坦150 mg相比,对于未经治疗或接受单药治疗的高血压患者的成本效益和成本效用。方法:研究者对四联超低剂量治疗高血压试验进行内部试验和建模经济评估。分析是预先计划的,并在试验期间获取药物和卫生服务的使用情况。 | Atkins ER Chye A Lung T Nolde JM Billot L Burke M Chalmers J Figtree GA Hay P Hillis GS Jansen S Marschner S Neal B Nelson MR Reid CM Usherwood T Schlaich M Chow CK Rodgers A 刘青 (译) 练桂丽(审校) | 2023 | 中华高血压杂志2023，31，11： | 0 |
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