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| 1 | Developing a bacteriophage cocktail for biocontrol of potato bacterial wilt显示文摘Bacterial wilt is a devastating disease of potato and can cause an 80% production loss. To control wilt using bacteriophage therapy, we isolated and characterized twelve lytic bacteriophages from different water sources in Kenya and China. Based on the lytic curves of the phages with the pathogen Ralstonia solanacearum, one optimal bacteriophage cocktail, P1, containing six phage isolations was formulated and used for studying wilt prevention and treatment efficiency in potato plants growing in pots. The preliminary tests showed that the phage cocktail was very effective in preventing potato bacterial wilt by injection of the phages into the plants or decontamination of sterilized soil spiked with R. solanacearum. Eighty percent of potato plants could be protected from the bacterial wilt(caused by R. solanacearum reference strain GIM1.74 and field isolates), and the P1 cocktail could kill 98% of live bacteria spiked in the sterilized soil at one week after spraying.However, the treatment efficiencies of P1 depended on the timing of application of the phages, the susceptibility of the plants to the bacterial wilt, as well as the virulence of the bacteria infected,suggesting that it is important to apply the phage therapy as soon as possible once there are early signs of the bacterial wilt. These results provide the basis for the development of bacteriophagebased biocontrol of potato bacterial wilt as an alternative to the use of antibiotics. | Cuihua Wei Junli Liu Alice Nyarnbura Maina Francis B Mwaura Junping Yu Chenghui Yan Ruofang Zhang Hongping Wei | 2017 | Virologica Sinica2017，32，6： | 8 |
| 2 | 以食物为基础的膳食模式与慢性疾病预防显示文摘Matthias B Schulze及其同事讨论了目前已知的膳食模式与癌症、冠心病、卒中及2型糖尿病的关联,重点在仍不确定的领域和未来的研究方向。 | Matthias B Schulze Miguel A Martínez-González Teresa T Fung Alice H Lichtenstein Nita G Forouhi 陈夏燕(译) 王燕芳(译) 武阳丰(校) | 2021 | 英国医学杂志中文版2021，24，3： | 3 |
| 3 | Reverse transcription-PCR analysis of the regulation of the manganese peroxidase gene family显示文摘 | GETTEMY JM MA B ALIC M | 1998 | Appl Environ Microbiol1998，64，2： | 1 |
| 4 | Chemical characterization and ecotoxicity of three soil foaming agents used in mechanized tunneling显示文摘 | Diego B Eleonora L Alice P | 2015 | Journal of Hazardous Materials2015，296，： | 1 |
| 5 | Inhibition of nucleoside transport By new analogues of nitrobenzylthioinosine显示文摘 | Deghati P Y F Alice B | 2003 | Bioorganic and Medicinal Chemistry2003，11，6： | 1 |
| 6 | Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats显示文摘 | Simonides Warner S Mulcahey Michelle A Redout Everaldo M Muller Alice Zuidwijk Marian J Visser Theo J Wassen Frank W J S Crescenzi Alessandra da-Silva Wagner S Harney John Engel Felix B Obregon Maria-Jesús Larsen P Reed Bianco Antonio C Huan | 2008 | Journal of Clinical Investigation2008，，3： | 1 |
| 7 | The effect of cues on gait vari- ability-reducing the attentional cost of walking in people with Parkinson's disease 显示文摘 | Katherine B Lynn R Alice N | 2008 | Parkinsonism Relat Disord2008，14，4： | 1 |
| 8 | Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis显示文摘 | Alice T Shaw Beow Y Yeap Benjamin J Solomon Gregory J Riely Justin Gainor Jeffrey A Engelman Geoffrey I Shapiro Daniel B Costa Sai-Hong I Ou Mohit Butaney Ravi Salgia Robert G Maki Marileila Varella-Garcia Robert C Doebele Yung-Jue Bang Kimary Kulig Pauli | 2011 | Lancet Oncology2011，，11： | 1 |
| 9 | Molecular barcodes detect redundancy and contamination in hair pin-bisulfite PCR 显示文摘 | Brooks E M Reinhard J S Alice F B | 2004 | Nucleic Acids Research2004，32，17： | 1 |
| 10 | Population growth, critical density, and the chance of extinction显示文摘 | Dennis B Alice effects | 1989 | Nat Resour Modeling1989，3，： | 1 |
| 11 | Effect of protease-activated receptors on guineapig ileum contraction in vitro显示文摘 | Wan B Y Alic A Peh K H | 2003 | Inilamm Res2003，52，： | 1 |
| 12 | Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis显示文摘 | Alice T Shaw Beow Y Yeap Benjamin J Solomon Gregory J Riely Justin Gainor Jeffrey A Engelman Geoffrey I Shapiro Daniel B Costa Sai-Hong I Ou Mohit Butaney Ravi Salgia Robert G Maki Marileila Varella-Garcia Robert C Doebele Yung-Jue Bang Kimary Kulig Pauli | 2011 | Lancet Oncology2011，，11： | 1 |
| 13 | Use of nuclear mutants in the analysis of chloroplast development 显示文摘 | William C T Alice B Robert A M | 1987 | Dev Genet1987，8，： | 1 |
| 14 | Optimizing Polysilicon Thin-film Transistor Performance with Chemical-mechanical Polishing and Hydrogenation显示文摘 | Chan Alice B Y Nquyen | 1996 | IEEE Electron Device Letters1996，17，11： | 1 |
| 15 | Use of nuclear mutants in the analysis of chloroplast development显示文摘 | WILLIAM C T ALICE B ROBERT A M | 1987 | Development Genetics1987，8，： | 1 |
| 16 | Un- calibrated stroke volume variations are able to predict the hemodynamic effects of positive end-expiratory pressure in pa- tients with acute lung injury or acute res- piratory distress syndrome after liver transplantation 显示文摘 | Mattieu B Karine N Alice Q | 2009 | Anesthesiology2009，111，： | 1 |
| 17 | Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas 显示文摘 | Karen SA Alice B Nikolai BR | 2000 | Proc Natl Acad Sci2000，97，12： | 1 |
| 18 | Integration of growth and patterning during vascular tissue formation in Arabidopsis显示文摘 | BERT DE R MILAD A ALICE S B | 2014 | Science2014，345，6197： | 1 |
| 19 | Changes in microbial community structure following herbicide (glyphosate) additions to forest soils 显示文摘 | ALICE W R MATT D B CAROL J S | 2006 | Applied Soil Ecology2006，34，23： | 1 |
| 20 | Cochlear implantation in the elderly: surgical and hearing outcomes 显示文摘 | Alice B Silvia M Laura G | 2013 | BMC Surg2013，13，2： | 1 |
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