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5788篇 您的检索式:期刊名="Autoimmun"
    题名 作者 年代 出处 被引量
1Th17 and regulatory T cell balance in autoimmune and inflammatory diseases显示文摘Mélissa Noack Pierre Miossec 2013Autoimmunity Reviews2013,,:2
2Alopecia Areata: A tissue specific autoimmune disease of the hair follicle显示文摘Amos Gilhar Richard S. Kalish 2005Autoimmunity Reviews2005,,1:2
3lncRNAX-inactive-specific transcript is a potential biomarker related to changes in CD4+T cell levels in systemic lupus erythematosus显示文摘Background:Systemic lupus erythematosus(SLE)is a particularly heterogeneous autoimmune disease.This study was intended to clarify the correlations between X-inactive-specific transcript(XIST)expression and SLE clinical features and the contribution of XIST to SLE pathogenesis at the transcriptome level.Methods:XIST expression in 79 SLE patients,14 rheumatoid arthritis patients,and 23 healthy controls was determined by quantitative polymerase chain reaction.The Benjamini and Hochberg adjusted method and multivariate linear regression were applied to correct p-values and adjust confounding factors,respectively.Bioinformatic methods were used to explore the function and regulatory mechanism of XIST.Results:XIST was significantly elevated in peripheral blood mononuclear cells and CD4^(+)T cells from SLE patients compared with the levels in healthy controls and had potential diagnostic value for SLE.Notably,XIST expression was positively correlated with the SLE disease activity index and significantly reduced after effective treatment.Moreover,SLE patients with high XIST expression tended to have elevated levels of CD4^(+)T cells,but reduced levels of NK cells.Bioinformatic analyses suggested that XIST may regulate OLFM4 and CEACAM8 expression by acting as a spongy body for miR-20a,miR-92a,miR-106a,and miR-449a.Furthermore,CEACAM8 was significantly upregulated in CD4^(+)T cells from SLE patients and significantly positively correlated with XIST expression.Conclusions:lncRNA XIST,a potential diagnostic and therapeutic biomarker for SLE,is involved in the change of immune cell balance in the peripheral blood of SLE patients.Mechanistically,XIST may regulate the miR-17-92-CEACAM8 axis to achieve this in CD4^(+)T cells.Qi Cheng Xin Chen Jieying Xu Mo Chen Peiyu Zhang Huaxiang Wu Yan Du 2022Rheumatology & Autoimmunity2022,2,3:2
4Familial primary biliary cirrhosis in Hiroshima显示文摘Tsuji K Watamabe Y Vande J 1999J Autoimmun1999,13,:2
5Infectome: A platform to trace infectious triggers of autoimmunity显示文摘Dimitrios P. Bogdanos Daniel S. Smyk Pietro Invernizzi Eirini I. Rigopoulou Miri Blank Shideh Pouria Yehuda Shoenfeld 2013Autoimmunity Reviews2013,,7:2
6Inflammatory bowel disease: the role of environmental factors显示文摘Silvio Danese Miquel Sans Claudio Fiocchi 2004Autoimmunity Reviews2004,,5:2
7Epigenetic considerations and the clinical reevaluation of the overlap syndrome between primary biliary cirrhosis and autoimmune hepatitis显示文摘Qixia Wang Carlo Selmi Xinmin Zhou Dekai Qiu Zenshan Li Qi Miao Xiaoyu Chen Jianhong Wang Edward L. Krawitt M. Eric Gershwin Ying Han Xiong Ma 2012Journal of Autoimmunity2012,,:2
8Optimizing anti-TNF treatments in inflammatory bowel disease显示文摘Shomron Ben-Horin Uri Kopylov Yehuda Chowers 2013Autoimmunity Reviews2013,,:2
9Y chromosome loss in male patients with primary biliary cirrhosis显示文摘Ana Lleo Sabine Oertelt-Prigione Ilaria Bianchi Lisa Caliari Palma Finelli Monica Miozzo Roberta Lazzari Annarosa Floreani Francesca Donato Massimo Colombo M. Eric Gershwin Mauro Podda Pietro Invernizzi 2013Journal of Autoimmunity2013,,:2
10Commercial blot assays in the diagnosis of systemic rheumatic diseases显示文摘Anna Ghirardello Raffaele Bendo Maria Elisa Rampudda Nicola Bassi Sandra Zampieri Andrea Doria 2009Autoimmunity Reviews2009,,8:2
11Human FoxP3 + regulatory T cells in systemic autoimmune diseases显示文摘Makoto Miyara Guy Gorochov Michael Ehrenstein Lucile Musset Shimon Sakaguchi Zahir Amoura 2011Autoimmunity Reviews2011,,12:2
12Clinical features and prognosis of patients with idiopathic inflammatory myopathies and anti-Jo-1 antibodies 显示文摘Mielnik P Wiesik-Szewczyk E Olesinska M 2006Autoimmunity2006,39,3:1
13DNA methylation in T cells from idiopathic lupus and drag-induced lupus patients显示文摘Zhou Y Lu Q 2008Autoimmun Rev2008,7,5:1
14IPEX and FOXP3:clinical and research perspectives显示文摘Wildin RS Freitus A 2005J Autoimmunity2005,,:1
15Construction and characterization of a single-chain antibody fragment derived from thymus of a patient with myasthenia gravis 显示文摘Meng F Stassen M H Schillberg S 2002Autoimmunity2002,35,2:1
16Anti-heart autoantibodies in familial dilated cardiomyopathy显示文摘Caforio AL Vinci A nieeto S 2008Autoimmunity2008,41,6:1
17Profile and clinical significance of anti-nuclear envelope antibodies found in patients with primary biliary cirrhosis:a multicenter study显示文摘Miyachi K Hankins RW Matsushima H 2003J Autoimmun2003,20,:1
18Mechanisms ofT regulatory cell function显示文摘Askenasy N Kaminitz A Yarkoni S 2008Autoimmun Rev2008,79,5:1
19Anti-thy roid peroxidase antibodies in thyroid disorders and non thyroid autoimmune disease显示文摘 Hermaden M Semple GW 1991Autoimmunity1991,3,1:1
20One year in autoimmunity显示文摘Carlo S 2007Autoimmunity Reviews2007,7,1:1
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