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| 1 | Low hypoxia inducible factor-1α(HIF-1α)expression in testicular germ cell tumors--a major reason for enhanced chemosensitivity?显示文摘The molecular basis for enhanced chemosensitivity of testicular germ cell tumors(GCT)has been an area of great interest,as it could potentially give us therapeutic leads in other resistant malignancies.Thus far,however,the increased sensitivity of GCT has been variously attributed to multiple factors—an inability to detoxify cisplatin,a lack of export pumps,an inability to repair the DNA damage,an intact apoptotic cascade and lack of p53 mutation;but a unifying underlying etiology leading to the aforementioned processes and having a translational implication has so far been elusive.Herein,we offer evidence to support a potential significant role for the previously demonstrated low hypoxia inducible factor-1α(HIF-1α)expression in mediating the general exquisite chemosensitivity of testicular GCT,through the aforementioned processes.This molecular mechanism based hypothesis could have a significant translational implication in platinum refractory GCT as well as other platinum resistant malignancies. | niraj shenoy roxana dronca fernando quevedo stephen a boorjian john cheville brian costello manish kohli thomas witzig lance pagliaro | 2017 | Chinese Journal of Cancer Research2017，29，4： | 4 |
| 2 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 3 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 4 | Review of 1027 Patients With Newly Diagnosed Multiple Myeloma显示文摘 | Robert A. Kyle Morie A. Gertz Thomas E. Witzig John A. Lust Martha Q. Lacy Angela Dispenzieri Rafael Fonseca S. Vincent Rajkumar Janice R. Offord Dirk R. Larson Matthew E. Plevak Terry M. Therneau Philip R. Greipp | 2003 | Mayo Clinic Proceedings2003，，1： | 2 |
| 5 | Induction of Apoptosis in Malignant B Cells by Phenylbutyrate or Phenylacetate in Combination with Chemotherapeutic Agents显示文摘 | THOMAS E WITZIG MICHAEL TIMM | 2000 | Clinical Cancer Res2000，6，： | 1 |
| 6 | Radioimmunotherapy for B-cell non-Hodgkin lymphoma显示文摘 | Thomas E Witzig | 2006 | Best Practice & Research Clinical Haematology2006，19，4： | 1 |
| 7 | Review of 1027 Patients With Newly Diagnosed Multiple Myeloma显示文摘 | Robert A. Kyle Morie A. Gertz Thomas E. Witzig John A. Lust Martha Q. Lacy Angela Dispenzieri Rafael Fonseca S. Vincent Rajkumar Janice R. Offord Dirk R. Larson Matthew E. Plevak Terry M. Therneau Philip R. Greipp | 2003 | Mayo Clinic Proceedings2003，，1： | 1 |
| 8 | Peripheral blood absolute lymphocyte/monocyte ratio during rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone treatment cycles predicts clinical outcomes in diffuse large B-cell lymphoma显示文摘 | Luis F. Porrata Kay M. Ristow Thomas M. Habermann Thomas E. Witzig Joseph P. Colgan David J. Inwards Stephen M. Ansell Ivana N. Micallef Patrick B. Johnston Grzegorz Nowakowski Carrie A. Thompson Svetomir N. Markovic | 2014 | Leukemia & Lymphoma2014，，12： | 1 |
| 9 | Single-Agent Lenalidomide in Patients With Mantle-Cell Lymphoma Who Relapsed or Progressed After or Were Refractory to Bortezomib: Phase II MCL-001 (EMERGE) Study显示文摘 | Andre Goy Rajni Sinha Michael E. Williams Sevgi Kalayoglu Besisik Johannes Drach Radhakrishnan Ramchandren Lei Zhang Sherri Cicero Tommy Fu Thomas E. Witzig | 2013 | Journal of Clinical Oncology2013，，： | 1 |
| 10 | Rituximab Therapy for Refractory Biliary Strictures in Immunoglobulin G4–Associated Cholangitis显示文摘 | Mark Topazian Thomas E. Witzig Thomas C. Smyrk Jose S. Pulido Michael J. Levy Patrick S. Kamath Suresh T. Chari | 2008 | Clinical Gastroenterology and Hepatology2008，，3： | 1 |
| 11 | Serum-free light chain—a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia显示文摘 | William Martin Roshini Abraham Tait Shanafelt Raynell J. Clark Nancy Bone Susan M. Geyer Jerry A. Katzmann Arthur Bradwell Neil E. Kay Thomas E. Witzig | 2006 | Translational Research2006，，4： | 1 |
| 12 | Trends and outcomes of modern staging of solitary plasmacytoma of bone显示文摘 | Rahma Warsame Morie A. Gertz Martha Q. Lacy Robert A. Kyle Francis Buadi David Dingli Philip R. Greipp Suzanne R. Hayman Shaji K. Kumar John A. Lust Stephen J. Russell Thomas E. Witzig Joseph Mikhael Nelson Leung Steven R. Zeldenrust S. Vincent Rajkumar A | 2012 | Am. J. Hematol2012，，7： | 1 |
| 13 | SYK Inhibition Modulates Distinct PI3K/AKT- Dependent Survival Pathways and Cholesterol Biosynthesis in Diffuse Large B Cell Lymphomas显示文摘 | Linfeng Chen Stefano Monti Przemyslaw Juszczynski Jing Ouyang Bjoern Chapuy Donna Neuberg John G. Doench Agata M. Bogusz Thomas M. Habermann Ahmet Dogan Thomas E. Witzig Jeffery L. Kutok Scott J. Rodig Todd Golub Margaret A. Shipp | 2013 | Cancer Cell2013，，： | 1 |
| 14 | Durable responses after ibritumomah tiuxetan radioimmunotherapy for CD+20 B-celllymphoma:long-term follow-up of a phase 1/2study显示文摘 | Leo l Arturo Molina Thomas Witzig | 2004 | Blood2004，103，12： | 1 |
| 15 | Prognostic Impact of Microsatellite Instability and DNA Ploidy in Human Colon Carcinoma Patients显示文摘 | Frank A. Sinicrope Rafaela L. Rego Kevin C. Halling Nathan Foster Daniel J. Sargent Betsy La Plant Amy J. French John A. Laurie Richard M. Goldberg Stephen N. Thibodeau Thomas E. Witzig | 2006 | Gastroenterology2006，，3： | 1 |
| 16 | Absolute monocyte/lymphocyte count prognostic score is independent of immunohistochemically determined cell of origin in predicting survival in diffuse large B-cell lymphoma显示文摘 | Luis F. Porrata Kay Ristow Thomas M. Habermann Nazan Ozsan Ahmet Dogan William Macon Joseph P. Colgan Thomas E. Witzig David J. Inwards Stephen M. Ansell Ivana N. Micallef Patrick B. Johnston Grzegorz S. Nowakowski Carrie Thompson Svetomir N. Markovic | 2012 | Leukemia & Lymphoma2012，，11： | 1 |
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