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| 1 | Management of gastric variceal bleeding:Role of endoscopy and endoscopic ultrasound显示文摘Gastric varices(GVs)are notorious to bleed massively and often difficult to manage with conventional techniques.This mini-review addresses endoscopic management principles for gastric variceal bleeding,including limitations of ligation and sclerotherapy and merits of endoscopic variceal obliteration.The article also discusses how emerging use of endoscopic ultrasound provides optimism of better diagnosis,improved classification,innovative management strategies and confirmatory tool for eradication of GVs. | Mohit Girotra Saikiran Raghavapuram Rtika R Abraham Mrinal Pahwa Archna R Pahwa Rayburn F Rego | 2014 | World Journal of Hepatology2014，6，3： | 6 |
| 2 | Could sport be part of pediatric obesity prevention and treatment? Expert conclusions from the 28th European Childhood Obesity Group Congress显示文摘The prevalence of pediatric obesity continues to increase worldwide,bringing with it various metabolic,functional,social,and psychological complications.1 Both the prevention and treatment of childhood obesity must be based on multidisciplinary approaches combining nutrition,physical activity(PA),and psychological support.2 As an essential element of these multicomponent strategies,regular physical activity has been acknowledged as having beneficial effects on children's and adolescents,body composition,physical fitness,and metabolic profile,as well as on their health-related quality of life,social and psychological health,and academic achievement.3,4 Given that only a relatively small proportion of children and adolescents meet the public health recommendations for PA,5 and given that weight loss exercise-based interventions suffer from a high attrition rate,there is a clear need for appropriate PAs. | Susanne Ring-Dimitriou Peter Krustrup Manuel J Coelho-E-Silva Jorge Mota Andera Seabra Carla Rego Artur Mazur Elpis Vlachopapadopoulou Margerita Caroli Marie-Laure Frelut Eva Erhardt Anders Forslund Ema Boyland Daniel Weghuber David Thivel | 2019 | Journal of Sport and Health Science2019，8，4： | 3 |
| 3 | The influence on gear surface properties using shot peening with a bimodal media size distribution显示文摘 | R.R. Rego J.O. Gomes A.M. Barros | 2013 | Journal of Materials Processing Tech2013，，12： | 3 |
| 4 | Saturable plasmonic metasurfaces for laser mode locking显示文摘Metamaterials are artificial materials made of subwavelength elementary cells that give rise to unexpected wave properties that do not exist naturally.However,these properties are generally achieved due to 3D patterning,which is hardly feasible at short wavelengths in the visible and near-infrared regions targeted by most photonic applications.To overcome this limitation,metasurfaces,which are the 2D counterparts of metamaterials,have emerged as promising platforms that are compatible with planar nanotechnologies and thus mass production,which platforms the properties of a metamaterial into a 2D sheet.In the linear regime,wavefront manipulation for lensing,holography,and polarization control has been achieved recently.Interest in metasurfaces operating in the nonlinear regime has also increased due to the ability of metasurfaces to efficiently convert incident light into harmonic frequencies with unusual polarization properties.However,to date,the nonlinear absorption of metasurfaces has been mostly ignored.Here,we demonstrate that plasmonic metasurfaces behave as saturable absorbers with modulation performances superior to the modulation performance of other 2D materials and exhibit unusual polarimetric nonlinear transfer functions.We quantify the link between saturable absorption,the plasmonic resonances of the unit cell and their distribution in a 2D metasurface,and finally provide a practical implementation by integrating the metasurfaces into a fiber laser cavity operating in pulsed regimes driven by the metasurface properties.As such,this work provides new perspectives on ultrathin nonlinear saturable absorbers for applications where tunable nonlinear transfer functions are needed,such as in ultrafast lasers or neuromorphic circuits. | Jiyong Wang Aurelien Coillet Olivier Demichel Zhiqiang Wang Davi Rego Alexandre Bouhelier Philippe Grelu Benoit Cluzel | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 5 | Intraepithelial Effector (CD3 + )/Regulatory (FoxP3 + ) T-Cell Ratio Predicts a Clinical Outcome of Human Colon Carcinoma显示文摘 | Frank A. Sinicrope Rafaela L. Rego Stephen M. Ansell Keith L. Knutson Nathan R. Foster Daniel J. Sargent | 2009 | Gastroenterology2009，，4： | 2 |
| 6 | NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2^(V617F)-positive myeloproliferative neoplasm cells显示文摘Recent data indicate that IGF1R/IRS signaling is a potential therapeutic target in BCR-ABL1-negative myeloproliferative neoplasms(MPN);in this pathway,IRS2 is involved in the malignant transformation induced by JAK2^(V617F),and upregulation of IGF1R signaling induces the MPN phenotype.NT157,a synthetic compound designed as an IGF1R-IRS1/2 inhibitor,has been shown to induce antineoplastic effects in solid tumors.Herein,we aimed to characterize the molecular and cellular effects of NT157 in JAK2^(V617F)positive MPN cell lines(HEL and SET2)and primary patient hematopoietic cells.In JAK2^(V617F)cell lines,NT157 decreased cell viability,clonogenicity,and cell proliferation,resulting in increases in apoptosis and cell cycle arrest in the G2/M phase(p<0.05).NT157 treatment inhibited IRS1/2,JAK2/STAT,and NFκB signaling,and it activated the AP-1 complex,downregulated four oncogenes(CCND1,MYB,WT1,and NFKB1),and upregulated three apoptotic-related genes(CDKN1A,FOS,and JUN)(p<0.05).NT157 induced genotoxic stress in a JAK2/STAT-independent manner.NT157 inhibited erythropoietin-independent colony formation in cells from polycythemia vera patients(p<0.05).These findings further elucidate the mechanism of NT157 action in a MPN context and suggest that targeting IRS1/2 proteins may represent a promising therapeutic strategy for MPN. | Bruna Alves Fenerich Jaqueline Cristina Fernandes Ana Paula Nunes Rodrigues Alves Juan Luiz Coelho-Silva Renata Scopim-Ribeiro Priscila Santos Scheucher Christopher A.Eide Cristina E.Tognon Brian J.Druker Eduardo Magalhães Rego João Agostinho Machado-Neto Fabiola Traina | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 2 |
| 7 | Use of ANSYS for Thermal Analysis in Mass Concrete显示文摘 | Nailde de Amorim Coelho Lineu Jose Pedroso Joao Henrique da Silva Rego Antonio Alberto Nepomuceno | 2014 | Journal of Civil Engineering and Architecture2014，8，7： | 2 |
| 8 | Response of sorghum to fertilizer phosphorus and its residual in a Vertisol 显示文摘 | Sahrawat K L Rego T J Burford J R | 1995 | Fertilizer Research1995，41，1： | 2 |
| 9 | Dose-dependent infection rates of parasites produce the Allee effect in epidemiology 显示文摘 | Regoes R R Ebcrt D Bonhoeffer S | 2002 | Proc R Soc Lond B2002，269，： | 1 |
| 10 | Microwave applications in materials joining 显示文摘 | Siores E Do Rego D | 1995 | Journal of Materials Processing Technology1995，48，14： | 1 |
| 11 | Customer satisfaction, cash flow, and shareholder value显示文摘 | GRUCA REGO | 2005 | Journal of Marketing2005，69，： | 1 |
| 12 | The Relationship Market Structure Efficiency from a Customer Satisfaction Perspective 显示文摘 | Lopo Leotte Rego | 1998 | Advances in Consumer Research1998，，： | 1 |
| 13 | Electrodeposition of black chromium spectral- ly selective coatings from a Cr(III) - ionic liquid solution显示文摘 | Sonia Eugenio Carmen Mireya Rangel Rui Vilar Ana Maria Botelho do Rego | 2011 | Thin Solid Films2011，519，2： | 1 |
| 14 | Multistart tabu search and diversificationstrategies for the quadratic assignment problem显示文摘 | Ames T Rego C Glover F | 2009 | IEEE Transactionson Systems Man and Cybernetics:Part A Systems and Humans2009，39，11： | 1 |
| 15 | Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene显示文摘 | Persson H Kvist A Rego N | 2011 | Cancer Res2011，71，1： | 1 |
| 16 | Micro-displacement or bending measurement using a long-period fibre grating in a self-referenced fibre optic intensity sensor显示文摘 | BAPTIST J SANTOS S REGO G | 2006 | Optics Communications2006，260，1： | 1 |
| 17 | 简述1511年至现代葡萄牙与暹逻的关系显示文摘我1979年居住于澳门的时候,由澳门政府官印局出版了一部名为<简述葡暹关系:1511-1900>的小册子,全书共28页.是根据存放在澳门历史档案馆的资料编成写的.全书分为五部份:(1)16世纪初的果亚:1510年;马六甲:1511年;澳门:1557年.(2)进一步接触:商人、传教士与17世纪时期暹逻王对澳门的借款.(3)葡人的衰落与18世纪接触的减少,贸易衰退.(4)19世纪旧有关系的复苏,不完全条约与葡人的厂房.(5)结语. | Antonio da Silra Rego 王国强 | 2002 | 海交史研究2002，，2： | 1 |
| 18 | Influence of la- paroscopy and laparotomy on gasometry, leukocytes and eytokines in a rat abdominal sepsis model 显示文摘 | Filho IA Sobfinho AAH do Rego ACM | 2006 | Acta Cirdrgica Brasileira2006，21，： | 1 |
| 19 | Diagnostic value of cytokines and C-reactive protein in the first 24 hours of neonatal sepsis显示文摘 | Laborada G Rego M Jain A | 2003 | Am J Perinatol2003，20，8： | 1 |
| 20 | Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegeneractive diseases 显示文摘 | Rego AC Olivera CR | 2003 | Neurochem Res2003，28，10： | 1 |
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