5篇
您的检索式：作者名="niraj shenoy"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Low hypoxia inducible factor-1α(HIF-1α)expression in testicular germ cell tumors--a major reason for enhanced chemosensitivity?显示文摘The molecular basis for enhanced chemosensitivity of testicular germ cell tumors(GCT)has been an area of great interest,as it could potentially give us therapeutic leads in other resistant malignancies.Thus far,however,the increased sensitivity of GCT has been variously attributed to multiple factors—an inability to detoxify cisplatin,a lack of export pumps,an inability to repair the DNA damage,an intact apoptotic cascade and lack of p53 mutation;but a unifying underlying etiology leading to the aforementioned processes and having a translational implication has so far been elusive.Herein,we offer evidence to support a potential significant role for the previously demonstrated low hypoxia inducible factor-1α(HIF-1α)expression in mediating the general exquisite chemosensitivity of testicular GCT,through the aforementioned processes.This molecular mechanism based hypothesis could have a significant translational implication in platinum refractory GCT as well as other platinum resistant malignancies. | niraj shenoy roxana dronca fernando quevedo stephen a boorjian john cheville brian costello manish kohli thomas witzig lance pagliaro | 2017 | Chinese Journal of Cancer Research2017，29，4： | 4 |
| 2 | Sirolimus Conversion in Liver Transplant Recipients With Renal Dysfunction: A Prospective, Randomized, Single-Center Trial显示文摘 | Surendra Shenoy Karen L. Hardinger Jeffrey Crippin Niraj Desai Kevin Korenblat Mauricio Lisker-Melman Jeffrey A. Lowell William Chapman | 2007 | Transplantation2007，，10： | 1 |
| 3 | Pre-Liver Transplantation Locoregional Adjuvant Therapy for Hepatocellular Carcinoma as a Strategy to Improve Longterm Survival显示文摘 | Ankit Bharat Daniel B. Brown Jeffrey S. Crippin Jennifer E. Gould Jeffrey A. Lowell Surendra Shenoy Niraj M. Desai William C. Chapman | 2006 | Journal of the American College of Surgeons2006，，4： | 1 |
| 4 | Pre-Liver Transplantation Locoregional Adjuvant Therapy for Hepatocellular Carcinoma as a Strategy to Improve Longterm Survival显示文摘 | Ankit Bharat Daniel B. Brown Jeffrey S. Crippin Jennifer E. Gould Jeffrey A. Lowell Surendra Shenoy Niraj M. Desai William C. Chapman | 2006 | Journal of the American College of Surgeons2006，，4： | 1 |
| 5 | Link between dysregulated hypoxia signaling and aberrant methylation in clear cell renal cell carcinoma?显示文摘Dysregulated pseudo-hypoxia(through its effects on cell survival,angiogenesis,metabolism,invasion)and epigenetic dysregulation[through widespread suppression of tumor suppressor genes involved in cell cycle,apoptosis,adhesion immune evasion,etc.(1)]are considered to be the two central driving pathogenic features in the progression of clear cell Renal Cell Carcinoma(cc RCC)(2,3).These | Niraj Shenoy | 2017 | Chinese Journal of Cancer Research2017，29，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员