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| 1 | Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。 | R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren | 2011 | Cell Research2011，21，10： | 6 |
| 2 | Validity and Reliability of Chinese Physical Activity Questionnaire for Children Aged 10-17 Years显示文摘Objective This study is aimed to report the development,the reliability and validity of the Chinese Children Physical Activity Questionnaire(CCPAQ)which was designed for the assessment of physical activity pattern in young population in China.Methods The CCPAQ was administered for two times in 119 children(mean age 13.1±2.4 years;boys 47%)to examine reliability by using intraclass correlation coefficients.Validity was determined in 106 participants by agreement with the CCPAQ measures and the objective method,the ActiGraph accelerometer.Data on physical activity patter n including time spe nt on d iff ere nt intensi ties and total physical activity,sedentary behavior as well as physical activity energy expenditure were used to assess the validity with Spearman's correlation coefficient and the Bland-Altman plots.Results The reliability coefficient of the CCPAQ ranged from 0.63-0.93(Intra-class correlation coefficient).Spearman's correlation coefficient for validity of time spent on total physical activity and sedentary behavior were all 0.32(P<0.001),and for physical activity energy expenditure was 0.58(P<0.001).Time spent on moderate-to-vigorous physical activity and light physical activity showed a relatively low correlation with the accelerometer(rho=0.20,P=0.040;rho=0.19,P=0.054).Conclusion The CCPAQ appears to be a promising and feasible method to assess physical activity pattern in Chinese children. | YANG Xi JAGO Russell ZHAI Yi YANG Zhen Yu WANG Yu Ying SI Xiang WANG Jun GAO Jian Fen CHEN Jing Ron YU Ying Jie ZHAO Wen Hua | 2019 | Biomedical and Environmental Sciences2019，32，9： | 6 |
| 3 | Analytical solution of thermal resistance of vapor chamber heat sink with and without pillar显示文摘 | Hsieh Shou Shing Lee Ron Yu | 2007 | Energy Conversion and Management2007，48，： | 1 |
| 4 | Characterization of the Weaklink of Wool Fibers显示文摘 | Yu Weidong Postle Ron Yan Haojing | 2003 | Journal of Applied Polymer Science2003，905，： | 1 |
| 5 | Compositional effects of nanocrystalline lithium zirconate on its CO2 capture properties显示文摘 | Ochoa-Fernandez Esther Ronning Magnus Yu Xiaofeng | 2008 | Industrial and Engineering Chemistry Research2008，47，2： | 1 |
| 6 | Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus 显示文摘 | Nierman WC Pain A Anderson MJ Wortman JR Kim HS Arroyo J Berriman M Abe K Archer DB Bermejo C Bennett J Bowyer P Chen D Collins M Coulsen R Davies R Dyer PS Farman M Fedorova N Fedorova N Feldblyum TV Fischer R Fosker N Fraser A Garcla JL Garcia MJ Goble A Goldman GH Gomi K Griffith- Jones S Gwilliam R Haas B Haas H Harris D Horiuchi H Huang J Humphray S Jim6nez J Keller N Khouri H Kitamoto K Kobayashi T Konzack S Kulkarni R Kumagai T Lafon A Latgo JP Li W Lord A Lu C Majoros WH May GS Miller BL Mohamoud Y Molina M Monod M Mouyna I Mulligan S Murphy L O'Neil S Paulsen I Pefialva MA Pertea M Price C Pritchard BL Quail MA Rabbinowitsch E Rawlins N Rajandream MA Reichard U Renauld H Robson GD Rodriguez de Cordoba S Rodriguez-Pefia JM Ronning CM Putter S Salzberg SL Sanchez M Sfnchez-Ferrero JC Saunders D Seeger K Squares R Squares S Takeuchi M Tekaia F Turner G Vazquez de Aldana CR Weidman J White O Woodward J Yu JH Fraser C Galagan JE Asai K Machida M Hall N Barrell B Denning DW | 2005 | Nature2005，438，7071： | 1 |
| 7 | Mutations in the Myosin VIIA Gene Cause a Wide Phenotypic Spectrum, Including Atypical Usher Syndrome显示文摘 | Xue-Zhong Liu Carolyn Hope James Walsh Valerie Newton Xiao Mei Ke Chuan Yu Liang Li Ron Xu Jiu Mu Zhou Dorothy Trump Karen P. Steel Sarah Bundey Steve D.M. Brown | 1998 | The American Journal of Human Genetics1998，，3： | 1 |
| 8 | Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences显示文摘 | Kaul M Yu H Ron Y | 1998 | Virology1998，249，1： | 1 |
| 9 | Cryopreservation of mature human oocytes by vitrification with ethylene glycol in straws显示文摘 | Shee Uan Chen Yin Ron Lie Kuang Han Chao Hsin Fen Lu Hong Nemg Ho Yu Shin Yang | 2000 | Fertility and sterility2000，74，4： | 1 |
| 10 | Can learning be virtually boosted? An investigation of online social networking impacts显示文摘 | Angela Yan Yu Stella Wen Tian Douglas Vogel Ron Chi-Wai Kwok | 2010 | Computers & Education2010，，4： | 1 |
| 11 | Can learning be virtually boosted? An investigation of online social networking impacts显示文摘 | Angela Yah Yu Stella Wen Tiart Douglas Vogel & Ron Chi-Wai Kwok | 2010 | Computers & Education2010，，55： | 1 |
| 12 | Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences显示文摘 | Kaul M Yu H Ron Y | 1998 | Virology1998，249，1： | 1 |
| 13 | Molecular dynamics and free energy studies on the wild-type and double mutant HIV-1 protease complexed with amprenavir and two amprenavir-related inhibitors: mechanism for binding and drug resistance 显示文摘 | Hou Tingjun Yu Ron | 2007 | Journal of Medicinal Chemistry2007，50，： | 1 |
| 14 | High rate of recombination throughout the human immunodeficiency virus type 1 genome 显示文摘 | Jetzt AE Yu H Klarmann GJ Ron Y Preston BD Dougherty JP | 2000 | J Virol2000，74，3： | 1 |
| 15 | Analysis and prediction of the tensile behaviour of wool fibre and bundles显示文摘 | Yu Weidong Ron Postle Yan Haojing | 2002 | Proceeding of the 3rd China International Wool Textile Conference2002，，9： | 1 |
| 16 | A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells显示文摘 | Maxim A. Vodyanik Junying Yu Xin Zhang Shulan Tian Ron Stewart James A. Thomson Igor I. Slukvin | 2010 | Cell Stem Cell2010，，： | 1 |
| 17 | Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences显示文摘 | Kaul M Yu H Ron Y | 1998 | Virology1998，249，1： | 1 |
| 18 | The nature of human immunodefieieney virus type 1 strand transfers 显示文摘 | Yu H Jetzt AE Ron Y | 1998 | J Biol Chem1998，273，28： | 1 |
| 19 | Science Missions Using CubeSats显示文摘As the role of missions and experiments carried out in outer space becomes more and more essential in our understanding of many earthly problems,such as resource management,environmental problems,and disaster management,as well as space science questions,thanks to their lower cost and faster development process CubeSats can benefit humanity and therefore,young scientists and engineers have been motivated to research and develop new CubeSat missions.Not very long after their inception,CubeSats have evolved to become accepted platforms for scientific and commercial applications.The last couple of years showed that they are a feasible tool for conducting scientific experiments,not only in the Earth orbit but also in the interplanetary space.For many countries,a CubeSat mission could prompt the community and young teams around the world to build the national capacity to launch and operate national space missions.This paper presents an overview of the key scientific and engineering gateways opened up to the younger scientific community by the advent and adaptation of new technology into CubeSat missions.The role of cooperation and the opportunities for capacity-building and education are also explored.Thus,the present article also aims to provide useful recommendations to scientists,early-career researchers,engineers,students,and anyone who intends to explore the potential and opportunities offered by CubeSats and CubeSats-based missions. | SEYEDABADI M E FALANGA M AZAM M BARESI N FLÉRON R JANTARACHOTE V JUAREZ ORTIZ V A JULCA YAYA J J LANGER M MANUTHASNA S MARTINOD N MUGHAL M R NOMAN M PARK J PIMNOO A PRAKS J REYNERI L SANNA A ŞIŞMAN TÇ SOME J ULAMBAYAR T YU Xiaozhou DONG Xiaolong BALDIS L | 2020 | 空间科学学报2020，40，4： | 0 |
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